M. R. Wiley

D-Phe-Pro-p-Amidinobenzylamine: A potent and highly selective thrombin inhibitor

N. Chirgadze, D. Clawson, N. D. Jones, 1996 .

A Highly Selective Hydantoin Inhibitor of Aggrecanase-1 and Aggrecanase-2 with a Low Projected Human Dose.

K. Thirunavukkarasu, D. Mudra, M. Chambers, 2017, Journal of medicinal chemistry.

A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs.

K. Duffin, S. Chandrasekhar, K. Thirunavukkarasu, 2010, Osteoarthritis and cartilage.

Identification of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 that are efficacious in both chemical and surgical models of osteoarthritis.

K. Thirunavukkarasu, V. Klimkowski, M. Chambers, 2014, Journal of medicinal chemistry.

Use of Osmotic Pumps to Establish the Pharmacokinetic-Pharmacodynamic Relationship and Define Desirable Human Performance Characteristics for Aggrecanase Inhibitors.

K. Thirunavukkarasu, D. Mudra, M. Chambers, 2016, Journal of medicinal chemistry.

Development of a novel clinical biomarker assay to detect and quantify aggrecanase-generated aggrecan fragments in human synovial fluid, serum and urine.

K. Duffin, K. Thirunavukkarasu, C. Swearingen, 2010, Osteoarthritis and cartilage.

Enhanced Protein C Activation and Inhibition of Fibrinogen Cleavage by a Thrombin Modulator

B. Grinnell, M. R. Wiley, D. T. Berg, 1996, Science.