C. Noble

发表

Ligand-Bound Structures of the Dengue Virus Protease Reveal the Active Conformation

P. Shi, C. Noble, C. Seh, 2011, Journal of Virology.

Structural biology of dengue virus enzymes: towards rational design of therapeutics.

P. Shi, C. Noble, 2012, Antiviral research.

Quinolone-DNA Interaction: Sequence-Dependent Binding to Single-Stranded DNA Reflects the Interaction within the Gyrase-DNA Complex

A. Maxwell, C. Noble, Faye M. Barnard, 2003, Antimicrobial Agents and Chemotherapy.

RNA polymerase II CTD phosphopeptides compete with RNA for the interaction with Pcf11.

I. Taylor, A. Ramos, C. Noble, 2006, RNA.

Structural Basis of Mycobacterial Inhibition by Cyclomarin A

Srinivasa P. S. Rao, D. Vasudevan, C. Noble, 2013, The Journal of Biological Chemistry.

The natural product cyclomarin kills Mycobacterium tuberculosis by targeting the ClpC1 subunit of the caseinolytic protease.

P. Niyomrattanakit, D. Jeffery, M. Riwanto, 2011, Angewandte Chemie.

Bcl-xL and UVRAG Cause a Monomer-Dimer Switch in Beclin1*

Haiwei Song, E. Manser, C. Noble, 2008, Journal of Biological Chemistry.

Non-homologous end joining: the missing link

C. Noble, 2002 .

A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis

G. Bonamy, F. Blasco, B. Striepen, 2017, Nature.

MLN51 Stimulates the RNA-Helicase Activity of eIF4AIII

Haiwei Song, C. Noble, 2007, PloS one.

Difficulties and advancements in developing drugs for the treatment of dengue fever

P. Shi, C. Noble, 2013 .

A Conserved Pocket in the Dengue Virus Polymerase Identified through Fragment-based Screening*

Paul W Smith, P. Shi, S. Lim, 2016, The Journal of Biological Chemistry.

Crystal structure of dengue virus methyltransferase without S-adenosyl-L-methionine

P. Shi, Hongping Dong, C. Noble, 2014, Antiviral Research.

Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies

Yen-Liang Chen, P. Shi, J. Lescar, 2020, Journal of Virology.

Structure activity relationships of 4-hydroxy-2-pyridones: A novel class of antituberculosis agents.

Paul W Smith, S. Peukert, N. Ma, 2015, European journal of medicinal chemistry.

Strategies for development of Dengue virus inhibitors.

Yen-Liang Chen, P. Shi, W. Schul, 2010, Antiviral research.

The effects of metal ions on the structure and stability of the DNA gyrase B protein.

M. Palumbo, A. Maxwell, C. Sissi, 2005, Journal of molecular biology.

Ten years of dengue drug discovery: progress and prospects.

David Beer, Hongping Dong, Shahul Nilar, 2013, Antiviral research.

Small Molecule Inhibitors That Selectively Block Dengue Virus Methyltransferase*

Gang Wang, Hongping Dong, Thomas H. Keller, 2010, The Journal of Biological Chemistry.

The dengue virus NS5 protein as a target for drug discovery.

P. Shi, S. Lim, C. Noble, 2015, Antiviral research.

Solution and crystal structures of mRNA exporter Dbp5p and its interaction with nucleotides.

Daiwen Yang, Jing-Song Fan, Haiwei Song, 2009, Journal of molecular biology.

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling

Hongping Dong, Rishi Arora, Xuping Xie, 2016, PLoS pathogens.

Conformational Flexibility of the Dengue Virus RNA-Dependent RNA Polymerase Revealed by a Complex with an Inhibitor

Pei-Yong Shi, Yen-Liang Chen, P. Shi, 2013, Journal of Virology.

Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design.

Paul W Smith, P. Shi, R. Rao, 2016, Journal of medicinal chemistry.

Key features of the interaction between Pcf11 CID and RNA polymerase II CTD

Geoff Kelly, Andres Ramos, I. Taylor, 2005, Nature Structural &Molecular Biology.

Structure of a nucleotide-bound Clp1-Pcf11 polyadenylation factor

I. Taylor, B. Beuth, C. Noble, 2006, Nucleic acids research.

Rna14-Rna15 assembly mediates the RNA-binding capability of Saccharomyces cerevisiae cleavage factor IA.

I. Taylor, P. Walker, L. Calder, 2004, Nucleic acids research.

Chromatin remodelling: it's a tracking business

C. Noble, 2002 .

Discovery of Potent Non-nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from Fragment Screening and Structure-Guided Design.

P. Shi, S. Lim, S. Nilar, 2018, Advances in experimental medicine and biology.

The role of GyrB in the DNA cleavage-religation reaction of DNA gyrase: a proposed two metal-ion mechanism.

A. Maxwell, C. Noble, 2002, Journal of molecular biology.

Direct inhibitors of InhA are active against Mycobacterium tuberculosis

Paul W Smith, K. Kuhen, P. Tonge, 2015, Science Translational Medicine.

Crystal Structure of the Dengue Virus Methyltransferase Bound to a 5′-Capped Octameric RNA

P. Shi, J. Lescar, C. Bodenreider, 2010, PloS one.

NMR Analysis of a Novel Enzymatically Active Unlinked Dengue NS2B-NS3 Protease Complex*

Rong Li, P. Shi, S. Gayen, 2013, The Journal of Biological Chemistry.

A cocrystal structure of dengue capsid protein in complex of inhibitor

Xuping Xie, P. Shi, K. Choi, 2020, Proceedings of the National Academy of Sciences.

Generation and characterization of mouse monoclonal antibodies against NS4B protein of dengue virus.

Xuping Xie, P. Shi, J. Lescar, 2014, Virology.

Ten years of dengue drug discovery: progress and prospects.

Paul W Smith, Yen-Liang Chen, P. Shi, 2013, Antiviral research.

Strategies for development of Dengue virus inhibitors.

Yen-Liang Chen, P. Shi, W. Schul, 2010, Antiviral research.