K. Morgenstern

发表

Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide

M. Murcko, P. Caron, C. Rice, 1996, Cell.

Complementary DNA cloning and kinetic characterization of a novel intracellular serine proteinase inhibitor: mechanism of action with trypsin and factor Xa as model proteinases.

W. Kisiel, F. Grant, C. Sprecher, 1994, Biochemistry.

Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.

P. Gallant, A. Oliveira-dos-Santos, J. Newcomb, 2008, Journal of medicinal chemistry.

Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity.

P. Gallant, A. Oliveira-dos-Santos, J. Newcomb, 2008, Journal of medicinal chemistry.

Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.

Xin Huang, David Powers, Daniela Metz, 2006, Journal of medicinal chemistry.

Density‐dependent regulation of cell surface γ‐glutamyl transpeptidase in cultured glial cells

K. Morgenstern, L. D. De Bault, O. Hanson-Painton, 1992 .

Cell surface γ-glutamyl transpeptidase in live cultures

K. Morgenstern, O. Hanson-Painton, L. E. Bault, 1991 .

Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding.

J P Griffith, M. Murcko, P. Caron, 1998, Structure.

Sphingosine Kinase Activity Is Not Required for Tumor Cell Viability

K. Rex, A. Coxon, N. Walker, 2013, PloS one.

Screening for lysine-specific demethylase-1 inhibitors using a label-free high-throughput mass spectrometry assay.

A. Cheng, A. Long, Hao Chen, 2011, Analytical biochemistry.

Polynucleotide modulation of the protease, nucleoside triphosphatase, and helicase activities of a hepatitis C virus NS3-NS4A complex isolated from transfected COS cells

C. Lin, K. Hsiao, M. Su, 1997, Journal of virology.

Crystal structure of an inactive Akt2 kinase domain.

Xin Huang, P. Rose, Yan Gu, 2003, Structure.

Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors.

L. Toledo, J. Newcomb, D. Stover, 2000, Structure.

Molecular Cloning, Expression, and Partial Characterization of Two Novel Members of the Ovalbumin Family of Serine Proteinase Inhibitors (*)

W. Kisiel, S. Mathewes, D. Foster, 1995, The Journal of Biological Chemistry.

Structure guided design of a series of sphingosine kinase (SphK) inhibitors.

Holger Wesche, Frank Kayser, Alan C Cheng, 2013, Bioorganic & medicinal chemistry letters.

Regulation of protein kinase C activity in cerebral microvessels.

P. Grammas, P. Moore, K. Morgenstern, 1995, Molecular and chemical neuropathology.

Mechanistic role of an NS4A peptide cofactor with the truncated NS3 protease of hepatitis C virus: elucidation of the NS4A stimulatory effect via kinetic analysis and inhibitor mapping.

S. Raybuck, D. Livingston, S. Harbeson, 1997, Biochemistry.

Protein kinase C in rat cerebral microvessels.

D. Cooper, P. Grammas, K. Morgenstern, 1993, Molecular and chemical neuropathology.

Identification and Characterization of the Cytoplasmic Antiproteinase (CAP) in Human Platelets

K. Morgenstern, R. Schleef, M. Riewald, 1996, The Journal of Biological Chemistry.

Isolation and characterization of an intracellular serine proteinase inhibitor from a monkey kidney epithelial cell line.

W. Kisiel, J. Baker, A. Pastuszyn, 1993, The Journal of biological chemistry.

Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity.

P. Gallant, M. Morrison, D. Elbaum, 2006, Journal of medicinal chemistry.