P. Pathuri

发表

Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function

Andrew J. Woodhead, Gianni Chessari, Brent Graham, 2012, Nature chemical biology.

Selecting the Right Targets for Fragment‐Based Drug Discovery

T. G. Davies, Glyn Williams, H. Jhoti, 2016 .

Structural Biology and Anticancer Drug Design

H. Willems, H. Jhoti, D. Tisi, 2014 .

Expression, purification, crystallization and preliminary X-ray diffraction analysis of alpha-11 giardin from Giardia lamblia.

H. Luecke, P. Pathuri, E. Nguyen, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal structure of metastasis-associated protein S100A4 in the active calcium-bound form.

H. Luecke, L. Vogeley, P. Pathuri, 2008, Journal of molecular biology.

Discovery of ASTX029, A Clinical Candidate Which Modulates the Phosphorylation and Catalytic Activity of ERK1/2.

C. Murray, V. Berdini, L. Fazal, 2021, Journal of medicinal chemistry.

Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2.

C. Murray, V. Berdini, J. Castro, 2018, Journal of medicinal chemistry.

Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives.

F. Holding, V. Berdini, M. Tortorici, 2016, ACS chemical biology.

Fragment-based discovery of 6-azaindazoles as inhibitors of bacterial DNA ligase.

Paul N. Mortenson, E. Chiarparin, T. Heightman, 2014, ACS medicinal chemistry letters.

Apo and Calcium-Bound Crystal Structures of Cytoskeletal Protein Alpha-14 Giardin (Annexin E1) from the Intestinal Protozoan Parasite Giardia lamblia

H. Luecke, G. Ozorowski, S. Svärd, 2009 .

Apo and calcium-bound crystal structures of Alpha-11 giardin, an unusual annexin from Giardia lamblia.

H. Luecke, S. Svärd, P. Pathuri, 2007, Journal of molecular biology.

Fragment-to-Lead Medicinal Chemistry Publications in 2022.

I. D. de Esch, D. Erlanson, Andrew J Woodhead, 2024, Journal of medicinal chemistry.