C. Bardelle

发表

Inhibitors of the tyrosine kinase EphB4. Part 2: structure-based discovery and optimisation of 3,5-bis substituted anilinopyrimidines.

Jon Read, Andrew G. Leach, Andrew G Leach, 2008, Bioorganic & medicinal chemistry letters.

Structural and functional characterization of Factor VIII-delta II, a new recombinant Factor VIII lacking most of the B-domain.

M. Fontaine‐Aupart, J. Yon, S. Krishnan, 1991, The Biochemical journal.

High Throughput Screen for Inhibitors of Rac1 GTPase by Flow Cytometry

Mark B. Carter, David C Murray, Zhaoping Liu, 2017, Multidimensional Flow Cytometry Techniques for Novel Highly Informative Assays.

Discovery of a Potent and Selective ATAD2 Bromodomain Inhibitor with Antiproliferative Activity in Breast Cancer Models.

Nichola L. Davies, A. Rabow, S. Guichard, 2022, Journal of medicinal chemistry.

ATM Kinase Inhibitors: HTS Cellular Imaging Assay Using Cellomics™ ArrayScan VTI Platform.

J. Boros, C. Bardelle, 2017, Methods in molecular biology.

Membrane binding kinetics of factor VIII indicate a complex binding process.

B. Furie, G. E. Gilbert, B. Furie, 1993, The Journal of biological chemistry.

Phosphodiesterase 4 conformers: preparation of recombinant enzymes and assay for inhibitors.

T. Saeki, M. Ito, K. Nomoto, 1999, Analytical biochemistry.

High-throughput methods to detect dimerization of Bcl-2 family proteins.

J. Whitfield, K. Harada, C. Bardelle, 2003, Analytical biochemistry.

Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines.

Jon Read, Andrew G. Leach, Andrew G Leach, 2008, Bioorganic & medicinal chemistry letters.

Inhibitors of the Tyrosine Kinase EphB4. Part 3. Identification of Non-benzodioxole-Based Kinase Inhibitors.

D. Cross, B. Barlaam, R. Ducray, 2011 .

Development of a High-Content High-Throughput Screening Assay for the Discovery of ATM Signaling Inhibitors

Catherine Bardelle, J. Boros, C. Bardelle, 2012, Journal of biomolecular screening.

The discovery of benzanilides as c-Met receptor tyrosine kinase inhibitors by a directed screening approach.

Andrew G. Leach, J. Major, D. Buttar, 2011, Bioorganic & medicinal chemistry letters.

Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides

Paul Harper, Louise Ford, John Archer, 2019, Nature Communications.

Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series.

D. Cross, B. Barlaam, R. Ducray, 2011, Bioorganic & medicinal chemistry letters.

Inhibitors of the tyrosine kinase EphB4. Part 3: identification of non-benzodioxole-based kinase inhibitors.

D. Cross, B. Barlaam, R. Ducray, 2010, Bioorganic & medicinal chemistry letters.

Application of High-Throughput Flow Cytometry in Early Drug Discovery: An AstraZeneca Perspective

Mei Ding, Roger Clark, Catherine Bardelle, 2018, SLAS discovery : advancing life sciences R & D.

Development of a High-Throughput Cytometric Screen to Identify Anti-Wolbachia Compounds: The Power of Public–Private Partnership

B. Slatko, David C Murray, M. Wigglesworth, 2019, SLAS discovery : advancing life sciences R & D.

Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesis.

Mark Cockerill, J. Debreczeni, S. Guichard, 2015, Journal of medicinal chemistry.

Drug discovery for epigenetics targets.

N. Selmi, R. Sheppard, G. Holdgate, 2021, Drug Discovery Today.

High-throughput flow cytometry for drug discovery: principles, applications, and case studies.

David C Murray, C. Bardelle, Karin Kaspersson, 2017, Drug discovery today.

Validation of miniaturized one-step reverse transcription qPCR assays for high-throughput screening and comparison to a reporter gene methodology.

M. Wigglesworth, Kirsty Rich, C. Bardelle, 2015, Assay and drug development technologies.