E. Williams

发表

Inhibitors of the tyrosine kinase EphB4. Part 2: structure-based discovery and optimisation of 3,5-bis substituted anilinopyrimidines.

Jon Read, Andrew G. Leach, Andrew G Leach, 2008, Bioorganic & medicinal chemistry letters.

Expedient synthesis of biologically important sulfonylmethyl pyrimidines

L. Hassall, E. Williams, T. McGuire, 2014 .

Calcium influx into neurons can solely account for cell contact- dependent neurite outgrowth stimulated by transfected L1

F. Walsh, P. Doherty, E. Williams, 1992, The Journal of cell biology.

Cell proliferation, migration and CAM-dependent neurite outgrowth as developmental in vitro endpoints for screening teratogenic potential: Application to valproic acid and related analogues of varying potency.

V. Berezin, E. Bock, A. Schousboe, 1998, Toxicology in vitro : an international journal published in association with BIBRA.

The Production of Arachidonic Acid Can Account for Calcium Channel Activation in the Second Messenger Pathway Underlying Neurite Outgrowth Stimulated by NCAM, N‐Cadherin, and L1

F. Walsh, P. Doherty, E. Williams, 1994, Journal of neurochemistry.

Facile synthesis of 7-amino anilinoquinazolines via direct amination of the quinazoline core

J. Kettle, E. Williams, C. Harris, 2005 .

Evidence for and against a Pivotal Role of PI 3-Kinase in a Neuronal Cell Survival Pathway

P. Doherty, E. Williams, 1999, Molecular and Cellular Neuroscience.

Inhibitors of epidermal growth factor receptor tyrosine kinase: Novel C-5 substituted anilinoquinazolines designed to target the ribose pocket.

Andrew G. Leach, Paul D. Johnson, R. Morgentin, 2006, Bioorganic & medicinal chemistry letters.

Inhibitors of epidermal growth factor receptor tyrosine kinase: Novel C-5 substituted anilinoquinazolines designed to target the ribose pocket.

Paul D. Johnson, R. Morgentin, R. Bradbury, 2006, Bioorganic & medicinal chemistry letters.

Highly Regioselective Buchwald—Hartwig Amination at C-2 of 2,4-Dichloropyridine Enabling a Novel Approach to 2,4-Bisanilinopyridine (BAPyd) Libraries.

E. Williams, 2013 .

Synthesis of a 5-alkoxypyrido[4,3-d]pyrimidin-4(3H)-one derivative via a regioselective Meisenheimer N-oxide rearrangement

P. Kenny, Paul G. Mwashimba, J. Kettle, 2004 .

Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines.

Jon Read, Andrew G. Leach, Andrew G Leach, 2008, Bioorganic & medicinal chemistry letters.

Tyrosine kinase inhibitors can differentially inhibit integrin- dependent and CAM-stimulated neurite outgrowth

F. Walsh, P. Doherty, E. Williams, 1994, The Journal of cell biology.

Inhibition of FGF-stimulated phosphatidylinositol hydrolysis and neurite outgrowth by a cell-membrane permeable phosphopeptide

A. Prochiantz, F. Walsh, P. Doherty, 1996, Current Biology.

A Ca2+/Calmodulin Kinase Inhibitor, KN-62, Inhibits Neurite Outgrowth Stimulated by CAMs and FGF

F. Walsh, P. Doherty, E. Williams, 1995, Molecular and Cellular Neuroscience.

Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin

F. Walsh, P. Doherty, E. Williams, 1994, Neuron.

Neutral 5-substituted 4-anilinoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase.

James S. Scott, B. Barlaam, R. Bradbury, 2007, Bioorganic & medicinal chemistry letters.

Identification of an N-cadherin Motif That Can Interact with the Fibroblast Growth Factor Receptor and Is Required for Axonal Growth*

S. Skaper, F. Walsh, P. Doherty, 2001, The Journal of Biological Chemistry.

Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain

Gareth Williams, Vincenzo Di Marzo, Tiziana Bisogno, 2003, The Journal of cell biology.

Inhibitors of epidermal growth factor receptor tyrosine kinase: optimisation of potency and in vivo pharmacokinetics.

J. Kendrew, R. Bradbury, P. Ballard, 2006, Bioorganic & medicinal chemistry letters.

The COX‐2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brain

Gareth Williams, Rafael J. Yáñez-Muñoz, Gareth Williams, 2010, British journal of pharmacology.

Dimeric Versions of Two Short N-cadherin Binding Motifs (HAVDI and INPISG) Function as N-cadherin Agonists*

Gareth Williams, Gareth Williams, P. Doherty, 2002, The Journal of Biological Chemistry.

INP, a Novel N-cadherin Antagonist Targeted to the Amino Acids That Flank the HAV Motif

O. Blaschuk, Gareth Williams, P. Doherty, 2000, Molecular and Cellular Neuroscience.

A Novel Family of Cyclic Peptide Antagonists Suggests That N-cadherin Specificity Is Determined by Amino Acids That Flank the HAV Motif*

O. Blaschuk, P. Doherty, E. Williams, 2000, The Journal of Biological Chemistry.

Expression of a Dominant Negative FGF Receptor Inhibits Axonal Growth and FGF Receptor Phosphorylation Stimulated by CAMs

F. Walsh, P. Doherty, E. Williams, 1997, Neuron.

Discovery of AZD3147: a potent, selective dual inhibitor of mTORC1 and mTORC2.

C. A. Roberts, J. Culshaw, G. Currie, 2015, Journal of medicinal chemistry.

Selective inhibition of fibroblast growth factor (FGF)-stimulated mitogenesis by a FGF receptor-1-derived phosphopeptide.

P. Doherty, D. Dunican, E. Williams, 2001, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Selective Inhibition of Growth Factor-stimulated Mitogenesis by a Cell-permeable Grb2-binding Peptide*

F. Walsh, P. Doherty, D. Dunican, 1997, The Journal of Biological Chemistry.

The molecular basis of the cooperation between EGF, FGF and eCB receptors in the regulation of neural stem cell function

Gareth Williams, P. Doherty, D. Chambers, 2013, Molecular and Cellular Neuroscience.

A soluble chimeric form of the L1 glycoprotein stimulates neurite outgrowth

F. Walsh, P. Doherty, E. Williams, 1995, Neuron.

CAMs and Axonal Growth: A Critical Evaluation of the Role of Calcium and the MAPK Cascade

Gareth Williams, P. Doherty, E. Williams, 2000, Molecular and Cellular Neuroscience.

Neurite Outgrowth Stimulated by the Tyrosine Kinase Inhibitor Herbimycin A Requires Activation of Tyrosine Kinases and Protein Kinase C

F. Walsh, P. Doherty, E. Williams, 1994, Journal of neurochemistry.

The FGF receptor uses the endocannabinoid signaling system to couple to an axonal growth response

F. Walsh, P. Doherty, E. Williams, 2003, The Journal of cell biology.

A dimeric version of the short N-cadherin binding motif HAVDI promotes neuronal cell survival by activating an N-cadherin/fibroblast growth factor receptor signalling cascade

Gareth Williams, L. Facci, S. Skaper, 2004, Molecular and Cellular Neuroscience.

Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF.

F. Walsh, P. Doherty, E. Williams, 1994, Development.

Identification of pyrazolo-pyrimidinones as GHS-R1a antagonists and inverse agonists for the treatment of obesity

Nathaniel G. Martin, Robert D. M. Davies, P. Macfaul, 2013 .

Stimulation of mitogenesis by a cell-permeable PI 3-kinase binding peptide.

P. Doherty, D. Dunican, D. Derossi, 1998, Biochemical and biophysical research communications.

Ganglioside Inhibition of Neurite Outgrowth Requires Nogo Receptor Function

M. Pangalos, D. Joseph-McCarthy, Gareth Williams, 2008, Journal of Biological Chemistry.

Overcoming the Inhibitors of Myelin with a Novel Neurotrophin Strategy*

M. Pangalos, Gareth Williams, F. Walsh, 2005, Journal of Biological Chemistry.

FGF inhibits neurite outgrowth over monolayers of astrocytes and fibroblasts expressing transfected cell adhesion molecules.

F. Walsh, P. Doherty, E. Williams, 1995, Journal of cell science.

The FGF receptor uses the endocannabinoid signaling system to couple to an axonal growth response

F. Walsh, P. Doherty, E. Williams, 2003, The Journal of cell biology.