D. V. Vander Velde

发表

The effect of conformation of the acyloxyalkoxy-based cyclic prodrugs of opioid peptides on their membrane permeability.

R. Borchardt, S. Jois, A. Bak, 1999, The journal of peptide research : official journal of the American Peptide Society.

Effect of conformation on the rate of deamidation of vancomycin in aqueous solutions.

S. Jois, V. Stella, T. Siahaan, 2000, Journal of pharmaceutical sciences.

The effect of conformation on the membrane permeation of coumarinic acid- and phenylpropionic acid-based cyclic prodrugs of opioid peptides.

R. Borchardt, S. Jois, T. Siahaan, 1999, The journal of peptide research : official journal of the American Peptide Society.

Synthesis and conformational studies of dipeptides constrained by disubstituted 3-(aminoethoxy)propionic acid linkers.

J. Aubé, D. V. Vander Velde, D. S. Reddy, 2004, The Journal of organic chemistry.

Characterization of the solution conformations of leuprolide acetate.

M. Manning, D. V. Vander Velde, J. Meyer, 2002, The journal of peptide research : official journal of the American Peptide Society.

Cyclodextrin-catalyzed deacetylation of spironolactone is pH and cyclodextrin dependent.

V. Stella, P. Jarho, D. V. Vander Velde, 2000, Journal of pharmaceutical sciences.

The Effect of β-Turn Structure on the Passive Diffusion of Peptides Across Caco-2 Cell Monolayers

R. Borchardt, G. Knipp, T. Siahaan, 1997, Pharmaceutical Research.

Comprehensive study of sansalvamide A derivatives and their structure-activity relationships against drug-resistant colon cancer cell lines.

K. Mcguire, G. Lushington, K. Otrubova, 2008, Journal of medicinal chemistry.

Site-specifically traced drug release and biodistribution of a paclitaxel-antibody conjugate toward improvement of the linker structure.

A. Safavy, M. Carpenter, G. Georg, 2004, Bioconjugate chemistry.

Diastereomeric phosphonate ester adducts of chymotrypsin: 31P-NMR measurements.

D. V. Vander Velde, I. M. Kovach, L. McKay, 1993, Chirality.

Optimum doses of deuterium oxide and sodium bromide for the determination of total body water and extracellular fluid.

D. V. Vander Velde, P. R. Schloerb, L. Thomas, 1991, Journal of pharmaceutical and biomedical analysis.

The effect of beta-turn structure on the passive diffusion of peptides across Caco-2 cell monolayers.

R. Borchardt, G. Knipp, T. Siahaan, 1997, Pharmaceutical research.

Stability of the Thrombolytic Protein Fibrolase: Effect of Temperature and pH on Activity and Conformation

J. W. Mitchell, M. Manning, D. V. Vander Velde, 1991, Pharmaceutical Research.

Clinical pharmacology of deoxyspergualin in patients with advanced cancer.

H. Scher, C. Riley, A. Jakubowski, 1991, Cancer research.

Conformational study of cyclo(1,5)-Ac-Pen-Arg-Gly-Asp-Cys-NH2 in water by NMR and molecular dynamics.

T. Siahaan, D. V. Vander Velde, S. Chakrabarti, 1992, Biochemical and biophysical research communications.

The effect of the aromatic rings of taxol on biological activity and solution conformation: synthesis and evaluation of saturated taxol and taxotere analogues.

R. Himes, G. Georg, D. V. Vander Velde, 1994, Journal of medicinal chemistry.

Solution behavior of a novel type 1 interferon, interferon-tau.

Danny K. Chou, D. Katayama, R. Nayar, 2005, Journal of pharmaceutical sciences.

Effect of Zinc Binding on the Structure and Stability of Fibrolase, a Fibrinolytic Protein from Snake Venom

J. W. Mitchell, M. Manning, D. V. Vander Velde, 1992, Pharmaceutical Research.

Fibrolase. A fibrinolytic protein from snake venom.

M. Manning, D. V. Vander Velde, D. Pretzer, 1993, Pharmaceutical biotechnology.

Synthesis, Conformational Analysis, and Biological Evaluation of Heteroaromatic Taxanes.

R. Himes, M. Hepperle, G. Georg, 1996, The Journal of organic chemistry.

Characterization of the complexation of fluoroquinolone antimicrobials with metal ions by nuclear magnetic resonance spectroscopy.

C. Riley, F. Takusagawa, D. V. Vander Velde, 1993, Journal of Pharmaceutical and Biomedical Analysis.

Reaction discovery using microfluidic-based multidimensional screening of polycyclic iminium ethers.

John R. Goodell, J. Aubé, J. Porco, 2010, The Journal of organic chemistry.

Synthesis and conformation of Gly-Gly dipeptides constrained with phenylalanine-like aminocaproic acid linkers.

J. Aubé, D. V. Vander Velde, J Aubé, 2000, Organic letters.

Synthesis and conformational analysis of a coumarinic acid-based cyclic prodrug of an opioid peptide with modified sensitivity to esterase-catalyzed bioconversion.

R. Borchardt, H. Ouyang, T. Siahaan, 2002, The journal of peptide research : official journal of the American Peptide Society.

Conformationally restricted paclitaxel analogues: macrocyclic mimics of the "hydrophobic collapse" conformation.

R. Himes, G. Georg, Z. J. Wu, 1999, Bioorganic & medicinal chemistry letters.

The oxetane conformational lock of paclitaxel: structural analysis of D-secopaclitaxel.

M. Hepperle, G. Georg, D. V. Vander Velde, 1999, Bioorganic & medicinal chemistry letters.

Synthesis and NMR-driven conformational analysis of taxol analogues conformationally constrained on the C13 side chain.

J. Snyder, R. Himes, G. Appendino, 2001, Journal of medicinal chemistry.

Dactylocyclines, novel tetracycline derivatives produced by a Dactylosporangium sp. III. Absolute stereochemistry of the dactylocyclines.

L. Mitscher, A. Tymiak, D. V. Vander Velde, 1992, The Journal of antibiotics.

A tandem Prins/Schmidt reaction approach to marine alkaloids: formal and total syntheses of lepadiformines A and C.

J. Aubé, D. V. Vander Velde, C. Katz, 2010, Organic letters.

Improved preparation and structural conformation of the fluorescence labelling reagents 1,2-diamino-4,5-dimethoxybenzene and 3,4-dihydro-6,7-dimethoxy-4-methyl-3-oxo-quinoxaline-2-carbonyl chloride.

C. Riley, J. Stobaugh, D. V. Vander Velde, 1990, Journal of pharmaceutical and biomedical analysis.

Novel d-seco paclitaxel analogues: synthesis, biological evaluation, and model testing.

J. Snyder, R. Himes, G. Georg, 2001, The Journal of organic chemistry.

Alectosarmentin, a new antimicrobial dibenzofuranoid lactol from the lichen, Alectoria sarmentosa.

L. Mitscher, D. V. Vander Velde, S. Drake, 1994, Journal of natural products.

Wallifoliol, a taxol congener with a novel carbon skeleton, from Himalayan Taxus wallichiana.

L. Mitscher, D. V. Vander Velde, S. R. Gollapudi, 1994, Journal of natural products.

Conformation of ATP and ADP bound to N10-formyltetrahydrofolate synthetase determined by TRNOE NMR spectroscopy.

R. Himes, D. V. Vander Velde, S. Song, 1994, Biochemistry.

Effect of stereochemistry on the transport of Aca-linked beta-turn peptidomimetics across a human intestinal cell line.

R. Borchardt, K. Tamura, D. V. Vander Velde, 1997, Bioorganic & medicinal chemistry.

A 19F NMR study of lomefloxacin in human erythrocytes and its interaction with hemoglobin.

M. Priston, C. Riley, D. V. Vander Velde, 1995, Journal of pharmaceutical and biomedical analysis.

Two-, three-, and four-dimensional nuclear magnetic resonance spectroscopy of protein pharmaceuticals.

M. Manning, J. Matsuura, D. V. Vander Velde, 1995, Pharmaceutical biotechnology.

A novel lumazine synthase inhibitor derived from oxidation of 1,3,6,8-tetrahydroxy-2,7-naphthyridine to a tetraazaperylenehexaone derivative.

A. Bacher, M. Fischer, G. Georg, 2007, The Journal of organic chemistry.

Hydrocotylosides I-VII, new oleanane saponins from hydrocotylesibthorpioides.

T. Miyase, H. Noguchi, Y. Sasaki, 2004, Journal of natural products.

Paclitaxel analogues from Taxus x media cv. Hicksii.

P. Orsini, G. Appendino, B. Gabetta, 1999, Journal of natural products.

Effect of Restricted Conformational Flexibility on the Permeation of Model Hexapeptides Across Caco-2 Cell Monolayers

R. Borchardt, G. Pauletti, T. Siahaan, 1997, Pharmaceutical Research.

Delta-sleep-inducing peptide: solution conformational studies of a membrane-permeable peptide.

M C Manning, R T Borchardt, R. Borchardt, 1994, Biochemistry.

Effect of buffer species on the thermally induced aggregation of interferon-tau.

C. Henry, M. Manning, Danny K. Chou, 2006, Journal of Pharmacy and Science.

Reactivity toward deamidation of asparagine residues in beta-turn structures.

R. Borchardt, R. Schowen, E. Topp, 2000, The journal of peptide research : official journal of the American Peptide Society.

Structure-activity studies of antitumor taxanes: synthesis of novel C-13 side chain homologated taxol and taxotere analogs.

G. Georg, J. Zygmunt, A. Datta, 1994, Journal of Medicinal Chemistry.

Transport characteristics of peptides and peptidomimetics: II. Hydroxyethylamine bioisostere-containing peptidomimetics as substrates for the oligopeptide transporter and P-glycoprotein in the intestinal mucosa.

S. L. Winslow, R. Borchardt, D. V. Vander Velde, 2001, The journal of peptide research : official journal of the American Peptide Society.

Identification of Inosine as an Endogenous Modulator for the Benzodiazepine Binding Site of the GABAA Receptors

Jang-Yen Wu, D. V. Vander Velde, R. G. Carlson, 1998, Journal of Biomedical Science.

Identification of inosine as an endogenous modulator for the benzodiazepine binding site of the GABAA receptors.

D. V. Vander Velde, R. G. Carlson, M. Yarom, 1998, Journal of biomedical science.

Synthetic studies with 13-deoxybaccatin III.

D. V. Vander Velde, Y. M. Ahn, Gunda Ingrid Georg, 2002, Journal of Organic Chemistry.

Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides.

R. Borchardt, B. Liederer, T. Siahaan, 2006, Journal of medicinal chemistry.

18Oxygen incorporation into inorganic phosphate in the reaction catalyzed byN 5,10‐methenyltetrahydrofolate synthetase

R. Himes, D. V. Vander Velde, K. Kounga, 1995, FEBS letters.

The Effect of Conformation on Membrane Permeability of an Acyloxyalkoxy-linked Cyclic Prodrug of a Model Hexapeptide

R. Borchardt, S. Jois, T. Siahaan, 1996, Pharmaceutical Research.