D. Ajjala

发表

Absorption, Distribution, Metabolism, Excretion (ADME), Drug-drug interaction potential and Prediction of Human Pharmacokinetics of SUVN-G3031, a Novel Histamine 3 Receptor (H3R) inverse agonist in Clinical development for the treatment of Narcolepsy.

Abdul Rasheed Mohammed, R. Nirogi, G. Bhyrapuneni, 2020, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

LC-MS/MS method for quantification of 3,4-dihydroxyphenylglycol, a norepinephrine metabolite in plasma and brain regions.

Abdul Rasheed Mohammed, R. Nirogi, N. Padala, 2019, Bioanalysis.

A definite measure of occupancy exposures, seeking with non-radiolabeled in vivo 5-HT2A receptor occupancy and in vitro free fractions

R. Nirogi, G. Bhyrapuneni, N. Muddana, 2018, Journal of receptor and signal transduction research.

Assessment of sigma-1 receptor occupancy in mice with non-radiolabelled FTC-146 as a tracer

Abdul Rasheed Mohammed, R. Nirogi, G. Bhyrapuneni, 2018, Journal of receptor and signal transduction research.

Simultaneous in-vivo receptor occupancy assays for serotonin 1A, 2A, and dopamine 2 receptors with the use of non-radiolabelled tracers: Proposed method in screening antipsychotics.

R. Nirogi, G. Bhyrapuneni, D. Ajjala, 2017, Journal of pharmacological and toxicological methods.

In‐vivo rat striatal 5‐HT4 receptor occupancy using non‐radiolabelled SB207145

R. Nirogi, V. Kandikere, M. Rasheed, 2013, The Journal of pharmacy and pharmacology.

Rat thalamic α₄β₂ neuronal nicotinic acetylcholine receptor occupancy assay using LC-MS/MS.

R. Nirogi, V. Kandikere, R. Saralaya, 2012, Journal of pharmacological and toxicological methods.

Skin sample preparation by collagenase digestion for diclofenac quantification using LC-MS/MS after topical application.

R. Nirogi, G. Bhyrapuneni, N. Muddana, 2016, Bioanalysis.

LC-MS/MS method for the determination of pitolisant: application to rat pharmacokinetic and brain penetration studies.

R. Nirogi, V. Kandikere, G. Bhyrapuneni, 2013, Biomedical chromatography : BMC.

Approach to reduce the non-specific binding in microdialysis

R. Nirogi, V. Kandikere, R. Saralaya, 2012, Journal of Neuroscience Methods.

Liquid chromatography tandem mass spectrometry method for the quantification of sarpogrelate, a selective 5-HT(₂A) receptor antagonist, in plasma: application to a pre-clinical pharmacokinetic study.

R. Nirogi, K. Mudigonda, V. Kandikere, 2010, Biomedical chromatography : BMC.

Inhibition of cytochrome P450 enzymes by saturated and unsaturated fatty acids in human liver microsomes, characterization of enzyme kinetics in the presence of bovine serum albumin (0.1 and 1.0% w/v) and in vitro – in vivo extrapolation of hepatic clearance

R. Nirogi, R. Ponnamaneni, G. Bhyrapuneni, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

LC-MS/MS method for the quantification of SUVN-G3031, a novel H3 receptor inverse agonist for narcolepsy treatment.

R. Nirogi, A. Shinde, D. Ajjala, 2020, Bioanalysis.

Liquid chromatography tandem mass spectrometry method for the quantification of rimonabant, a CB1 receptor antagonist, in human plasma.

R. Nirogi, K. Mudigonda, V. Kandikere, 2008, Biomedical chromatography : BMC.

A simple and rapid HPLC/UV method for the simultaneous quantification of theophylline and etofylline in human plasma.

R. Nirogi, K. Mudigonda, V. Kandikere, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Development and validation of sensitive LC–MS/MS method for the quantification of SUVN‐502 and its metabolite and its application for first in human pharmacokinetic study

R. Nirogi, N. Padala, D. Ajjala, 2017, Journal of pharmaceutical and biomedical analysis.

Quantification of pramipexole in human plasma by liquid chromatography tandem mass spectrometry using tamsulosin as internal standard.

S. Maurya, R. Nirogi, K. Mudigonda, 2007, Biomedical chromatography : BMC.

Methoxsalen as an in vitro phenotyping tool in comparison with 1-aminobenzotriazole

R. Nirogi, R. Ponnamaneni, Arunkumar Manoharan, 2019, Xenobiotica; the fate of foreign compounds in biological systems.

Sensitive liquid chromatography tandem mass spectrometry method for the quantification of Quetiapine in plasma.

K. Mukkanti, R. Nirogi, K. Mudigonda, 2008, Biomedical chromatography : BMC.

Dried blood spot analysis of an iron chelator--deferasirox and its potential application to therapeutic drug monitoring.

R. Nirogi, V. Kandikere, S. Srikakolapu, 2012, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

LC-MS/MS method for the quantification of aldose reductase inhibitor-epalrestat and application to pharmacokinetic study.

R. Nirogi, V. Kandikere, G. Bhyrapuneni, 2013, Journal of pharmaceutical and biomedical analysis.

Abstracts of Papers Presented at the 2008 Pittsburgh Conference

Ming Gu, Balaji Viswanathan, Scott Ramos, 2009, Journal of automated methods & management in chemistry.

Quantification of Oxcarbazepine and Its Active Metabolite 10-Hydroxycarbazepine in Human Plasma by High-performance Liquid Chromatography

R. Nirogi, K. Mudigonda, V. Kandikere, 2006, Arzneimittelforschung.

Chemical inhibitors of CYP450 enzymes in liver microsomes: combining selectivity and unbound fractions to guide selection of appropriate concentration in phenotyping assays

Ramakrishna Nirogi, R. Nirogi, R. Ponnamaneni, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

LC-MS/MS method for the quantification of almotriptan in dialysates: application to rat brain and blood microdialysis study.

R. Nirogi, V. Kandikere, S. Srikakolapu, 2013, Journal of pharmaceutical and biomedical analysis.

Incurred sample reanalysis of fingolimod and fingolimod phosphate in blood: stability evaluation and application to a rat pharmacokinetic study.

R. Nirogi, N. Padala, D. Ajjala, 2017, Bioanalysis.

Liquid chromatography tandem mass spectrometry method for the quantification of amisulpride with LLOQ of 100 pg/mL using 100 microL of plasma.

K. Mukkanti, R. Nirogi, K. Mudigonda, 2008, Biomedical chromatography : BMC.

HPLC quantification of the HIV-1 protease inhibitor saquinavir in brain and testis of mice.

R. Nirogi, K. Mudigonda, V. Kandikere, 2006, Biomedical chromatography : BMC.

SUVN-502, POTENT AND PURE 5-HT6 RECEPTOR ANTAGONIST: PROOF-OF-CONCEPT STUDY DESIGN IN MODERATE ALZHEIMER’S DISEASE PATIENTS

R. Nirogi, K. Mudigonda, A. Shinde, 2016, Alzheimer's & Dementia.

Simultaneous extraction of acetylsalicylic acid and salicylic acid from human plasma and simultaneous estimation by liquid chromatography and atmospheric pressure chemical ionization/tandem mass spectrometry detection

R. Nirogi, K. Mudigonda, V. Kandikere, 2011, Arzneimittelforschung.