C. Alvey

发表

Novel Application of the Two‐Period Microtracer Approach to Determine Absolute Oral Bioavailability and Fraction Absorbed of Ertugliflozin

D. Papadopoulos, A. Vaz, V. Sahasrabudhe, 2018, Clinical and translational science.

Safety and Pharmacology of a Single Intravenous Dose of Ponezumab in Subjects With Mild-to-Moderate Alzheimer Disease: A Phase I, Randomized, Placebo-Controlled, Double-Blind, Dose-Escalation Study

Qinying Zhao, M. Borrie, K. Bales, 2013, Clinical neuropharmacology.

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Domagrozumab (PF‐06252616), an Antimyostatin Monoclonal Antibody, in Healthy Subjects

C. Morris, S. Sherlock, S. Arkin, 2018, Clinical pharmacology in drug development.

Pharmacokinetics of Pregabalin in Subjects with Various Degrees of Renal Function

A. Sedman, E. Posvar, E. Randinitis, 2003, Journal of clinical pharmacology.

Influence of mild and moderate hepatic impairment on axitinib pharmacokinetics

R. Labadie, T. Marbury, Y. Pithavala, 2010, Investigational New Drugs.

Safety and Pharmacology of Ponezumab (PF-04360365) After a Single 10-Minute Intravenous Infusion in Subjects With Mild to Moderate Alzheimer Disease

Qinying Zhao, M. Bednar, A. Burstein, 2013, Clinical neuropharmacology.

Meta‐Analysis of Steady‐State Pharmacokinetics of Troglitazone and Its Metabolites

E. Randinitis, C. Loi, J. Koup, 1997, Journal of clinical pharmacology.

A phase I, open-label, mass balance study of [14C] dacomitinib (PF-00299804) in healthy male volunteers

G. Ni, C. Loi, C. Alvey, 2013, Cancer Chemotherapy and Pharmacology.

Extended‐Release Once‐Daily Formulation of Tofacitinib: Evaluation of Pharmacokinetics Compared With Immediate‐Release Tofacitinib and Impact of Food

J. Kushner, T. Stock, C. Alvey, 2016, Journal of clinical pharmacology.

Safety, tolerability, and pharmacokinetics of pregabalin in children with refractory partial seizures: A phase 1, randomized controlled study

E. Zegarac, J. Pellock, C. Alvey, 2014, Epilepsia.

Evaluation of a Janus kinase 1 inhibitor, PF‐04965842, in healthy subjects: A phase 1, randomized, placebo‐controlled, dose‐escalation study

S. Tarabar, E. Peeva, C. Banfield, 2018, British journal of clinical pharmacology.

Evaluation of the Effect of Tofacitinib on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Volunteers

Haihong Shi, S. Krishnaswami, C. Alvey, 2016, Clinical pharmacology in drug development.

Evaluation of the effect of fluconazole and ketoconazole on the pharmacokinetics of tofacitinib in healthy adult subjects

G. Chan, R. Labadie, G. Ni, 2014, Clinical pharmacology in drug development.

Lack of effect of tofacitinib (CP-690,550) on the pharmacokinetics of the CYP3A4 substrate midazolam in healthy volunteers: confirmation of in vitro data.

R. Walsky, M. Dowty, S. Krishnaswami, 2012, British journal of clinical pharmacology.

Single‐ and multiple‐dose pharmacokinetics of tofacitinib in healthy Chinese volunteers

Haihong Shi, S. Krishnaswami, C. Alvey, 2015, Clinical pharmacology in drug development.

Pharmacokinetics and pharmacodynamics of ponezumab (PF-04360365) following a single-dose intravenous infusion in patients with mild to moderate Alzheimer's disease

Qinying Zhao, M. Bednar, A. Burstein, 2010, Alzheimer's & Dementia.

Pharmacokinetics and Pharmacodynamics of Figitumumab, a Monoclonal Antibody Targeting the Insulin‐Like Growth Factor 1 Receptor, in Healthy Participants

D. Yin, A. Bello, C. Alvey, 2013, Journal of clinical pharmacology.

The Pharmacokinetics of Pregabalin in Breast Milk, Plasma, and Urine of Healthy Postpartum Women

A. Płotka, J. Scavone, C. Alvey, 2016, Journal of human lactation : official journal of International Lactation Consultant Association.

Pregabalin Drug Interaction Studies: Lack of Effect on the Pharmacokinetics of Carbamazepine, Phenytoin, Lamotrigine, and Valproate in Patients with Partial Epilepsy

M. Brodie, E. Posvar, E. Randinitis, 2005, Epilepsia.

Drug Interactions with Clinafloxacin

A. Sedman, E. Randinitis, N. Bron, 2001, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics (PK) of crizotinib (PF-02341066) in patients with advanced non-small cell lung cancer (NSCLC) and other solid tumors.

K. Wilner, A. Bello, C. Li, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Effects of fesoterodine on the pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers.

B. Malhotra, K. Gandelman, C. Alvey, 2011, British journal of clinical pharmacology.

Lack of an Effect of Standard and Supratherapeutic Doses of Linezolid on QTc Interval Prolongation

R. Labadie, B. Damle, C. Alvey, 2011, Antimicrobial Agents and Chemotherapy.

Pregabalin Controlled-Release Pharmacokinetics in Healthy Volunteers: Analysis of Four Multiple-Dose Randomized Clinical Pharmacology Studies

A. Płotka, J. Scavone, C. Alvey, 2014, Clinical Drug Investigation.

Clinical experience with moroctocog alfa (AF‐CC) in younger paediatric patients with severe haemophilia A: Two open‐label studies

J. Korth-Bradley, K. Kavaklı, J. Fuiman, 2018, Haemophilia : the official journal of the World Federation of Hemophilia.

Confirmation of longer FIX activity half-life with prolonged sample collection after single doses of nonacog alfa in patients with haemophilia B

R. Labadie, J. Korth-Bradley, R. Wu, 2017, Thrombosis and Haemostasis.

Effects of the moderate CYP3A4 inhibitor, fluconazole, on the pharmacokinetics of fesoterodine in healthy subjects.

M. Dickins, B. Malhotra, K. Gandelman, 2011, British journal of clinical pharmacology.

Pharmacokinetics and Bioequivalence Comparison of 600 mg Single-Dose Linezolid Oral Suspension and Tablet Formulation in Healthy Chinese Subjects

Qiang Wang, C. Alvey, Huifen Faye Wang, 2014 .

Steady‐State Pharmacokinetics and Dose Proportionality of Troglitazone and Its Metabolites

A. Sedman, E. Randinitis, C. Loi, 1999, Journal of clinical pharmacology.

Distribution, Metabolism, and Excretion of Gedatolisib in Healthy Male Volunteers After a Single Intravenous Infusion

B. Houk, L. Kirkovsky, Kyle T. Matschke, 2018, Clinical pharmacology in drug development.

Assessment of the Drug Interaction Potential of Ertugliflozin With Sitagliptin, Metformin, Glimepiride, or Simvastatin in Healthy Subjects

V. Sahasrabudhe, Haihong Shi, Yali Liang, 2018, Clinical pharmacology in drug development.

Clinical Pharmacokinetics of Pregabalin in Healthy Volunteers

B. Corrigan, E. Posvar, R. Boyd, 2010, Journal of clinical pharmacology.

Metabolic disposition of pregabalin in healthy volunteers

B. Corrigan, E. Posvar, W. Pool, 2001 .

Pharmacokinetics of Pregabalin Controlled-Release in Healthy Volunteers: Effect of Food in Five Single-Dose, Randomized, Clinical Pharmacology Studies

A. Płotka, J. Scavone, C. Alvey, 2014, Clinical Drug Investigation.

Effect of the Gastrointestinal Prokinetic Agent Erythromycin on the Pharmacokinetics of Pregabalin Controlled-Release in Healthy Individuals: A Phase I, Randomized Crossover Trial

A. Płotka, J. Scavone, C. Alvey, 2015, Clinical Drug Investigation.

Pharmacokinetic and safety profile of tofacitinib in children with polyarticular course juvenile idiopathic arthritis: results of a phase 1, open-label, multicenter study

A. Martini, C. Mebus, H. Brunner, 2017, Pediatric Rheumatology.

Safety and pharmacokinetics following a single 10-minute intravenous infusion of the anti-amyloid mAb ponezumab (PF-04360365) in patients with mild to moderate Alzheimer's disease

Qinying Zhao, M. Bednar, A. Burstein, 2010, Alzheimer's & Dementia.

The effect of mild and moderate hepatic impairment on the pharmacokinetics of tofacitinib, an orally active Janus kinase inhibitor

G. Chan, N. Lawendy, S. Krishnaswami, 2014, Clinical pharmacology in drug development.

Evaluation of the potential interaction between tofacitinib and drugs that undergo renal tubular secretion using metformin, an in vivo marker of renal organic cation transporter 2

M. Dowty, Haihong Shi, S. Krishnaswami, 2014, Clinical pharmacology in drug development.

Development and validation of a Level A in-vitro in-vivo correlation for tofacitinib modified-release tablets using extrudable core system osmotic delivery technology.

J. Kushner, T. Stock, C. Alvey, 2019, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Effect of Gemfibrozil and Fenofibrate on the Pharmacokinetics of Atorvastatin

L. Whitfield, C. Alvey, D. Hartman, 2011, Journal of clinical pharmacology.