G. Walkup

发表

Correction for Interference by Test Samples in High-Throughput Assays

T. Keating, Thomas A Keating, A. Shapiro, 2009, Journal of biomolecular screening.

Pyrrolamide DNA Gyrase Inhibitors: Fragment-Based Nuclear Magnetic Resonance Screening To Identify Antibacterial Agents

Ning Gao, Haihong Ni, Oluyinka Green, 2011, Antimicrobial Agents and Chemotherapy.

Peptidyl chemosensors incorporating a FRET mechanism for detection of Ni(II).

B. Imperiali, G. Walkup, D. Pearce, 1998, Bioorganic & Medicinal Chemistry Letters.

Rapid Tuberculosis Diagnosis Using Reporter Enzyme Fluorescence (REF)

E. Graviss, Suprateek Kundu, J. Cirillo, 2019 .

Selection and molecular characterization of ceftazidime/avibactam-resistant mutants in Pseudomonas aeruginosa strains containing derepressed AmpC.

R. Alm, R. Mclaughlin, James D. Whiteaker, 2015, The Journal of antimicrobial chemotherapy.

ESKAPEing the labyrinth of antibacterial discovery

Dean G. Brown, R. Tommasi, J. Manchester, 2015, Nature Reviews Drug Discovery.

ESKAPEing the labyrinth of antibacterial discovery

Dean G. Brown, R. Tommasi, J. Manchester, 2015, Nature Reviews Drug Discovery.

Corrigendum: Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases

M. Gowravaram, G. Basarab, V. Galullo, 2015, Scientific reports.

Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases

M. Gowravaram, G. Basarab, V. Galullo, 2015, Scientific Reports.

A New Cell-Permeable Fluorescent Probe for Zn2+

Roger Y. Tsien, Stephen J. Lippard, R. Tsien, 2000 .

Fluorescent sensors for Zn(2+) based on a fluorescein platform: synthesis, properties and intracellular distribution.

R. Tsien, S. Lippard, S. Burdette, 2001, Journal of the American Chemical Society.

Exploiting Polypeptide Motifs for the Design of Selective Cu(II) Ion Chemosensors

B. Imperiali, G. Walkup, A. Torrado, 1998 .

Stereoselective Synthesis of Fluorescent α-Amino Acids Containing Oxine (8-Hydroxyquinoline) and Their Peptide Incorporation in Chemosensors for Divalent Zinc

B. Imperiali, G. Walkup, 1998 .

Secreted Gaussia princeps Luciferase as a Reporter of Escherichia coli Replication in a Mouse Tissue Cage Model of Infection

S. McLeod, S. Fisher, Mingyu Liu, 2014, PloS one.

Avibactam is a covalent, reversible, non–β-lactam β-lactamase inhibitor

D. Ehmann, P. Ross, S. Fisher, 2012, Proceedings of the National Academy of Sciences.

Kinetics of Avibactam Inhibition against Class A, C, and D β-Lactamases

D. Ehmann, P. Ross, S. Fisher, 2013, The Journal of Biological Chemistry.

Mode Of Inhibition of a novel DNA gyrase inhibitor with activity against Neisseria gonorrhoeae Inhibition of Neisseria gonorrhoeae type II Topoisomerases by the Novel Spiropyrimidinetrione AZD 0914 * #

D. Ehmann, P. Doig, S. D. Mills, 2015 .

Discovery of Inhibitors of 4′-Phosphopantetheine Adenylyltransferase (PPAT) To Validate PPAT as a Target for Antibacterial Therapy

H. Ni, M. Johnstone, S. Lahiri, 2013, Antimicrobial Agents and Chemotherapy.

Translating slow-binding inhibition kinetics into cellular and in vivo effects.

Peter J Tonge, Virna J A Schuck, Zhiping You, 2015, Nature chemical biology.

Unnatural Amino Acids for the Design of Functional Proteins: Biomimetic Catalysis Using Coenzyme Amino Acids

B. Imperiali, G. Walkup, L. Wang, 1997 .

Corrigendum: Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases

M. Gowravaram, G. Basarab, V. Galullo, 2015, Scientific Reports.

Novel Bacterial NAD+-Dependent DNA Ligase Inhibitors with Broad-Spectrum Activity and Antibacterial Efficacy In Vivo

Kenneth D. Johnson, Wei Yang, A. Eakin, 2010, Antimicrobial Agents and Chemotherapy.

Structure guided understanding of NAD+ recognition in bacterial DNA ligases.

S. D. Mills, S. Lahiri, G. Walkup, 2012, ACS chemical biology.

In Vivo Activity and Antibacterial Efficacy Ligase Inhibitors with Broad-Spectrum

Kenneth D. Johnson, A. Eakin, S. D. Mills, 2013 .

A High-Throughput Fluorescence Resonance Energy Transfer-Based Assay for DNA Ligase

A. Eakin, A. Shapiro, G. Walkup, 2011, Journal of biomolecular screening.

Novel Bacterial NAD +-dependent DNA Ligase Inhibitors with 3 Broad Spectrum Activity and Antibacterial Efficacy In Vivo 4 5 6 Running title : Novel Bacterial NAD +-dependent DNA Ligase Inhibitors 7 8 9

Kenneth D. Johnson, Wei Yang, A. Eakin, 2010 .

Design and Evaluation of a Peptidyl Fluorescent Chemosensor for Divalent Zinc

B. Imperiali, G. Walkup, 1996 .

Rapid Tuberculosis Diagnosis Using Reporter Enzyme Fluorescence

E. Graviss, Suprateek Kundu, J. Cirillo, 2019, Journal of Clinical Microbiology.

New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications.

Robert E Campbell, Brent R. Martin, Roger Y Tsien, 2002, Journal of the American Chemical Society.

Inhibition of Neisseria gonorrhoeae Type II Topoisomerases by the Novel Spiropyrimidinetrione AZD0914*

D. Ehmann, G. Basarab, P. Doig, 2015, The Journal of Biological Chemistry.

Evaluation of pKa Estimation Methods on 211 Druglike Compounds

John Manchester, Grant Walkup, Olga Rivin, 2010, J. Chem. Inf. Model..

Stereoselective Synthesis of Fluorescent α‐Amino Acids Containing Oxine (8‐Hydroxyquinoline) and Their Peptide Incorporation in Chemosensors for Divalent Zinc.

B. Imperiali, G. Walkup, 1999 .

Peptide platforms for metal ion sensing

Barbara Imperiali, Dierdre A. Pearce, Jean-Ernest Sohna Sohna, 1999, Optics East.

New directions using reporter enzyme fluorescence (REF) as a tuberculosis diagnostic platform.

J. Cirillo, P. Sule, G. Walkup, 2016, Tuberculosis.

Avibactam is a covalent, reversible, non–β-lactam β-lactamase inhibitor

D. Ehmann, P. Ross, S. Fisher, 2012, Proceedings of the National Academy of Sciences.

A High-Throughput Absorbance-Based Assay for Methionine Produced by Methionine Aminopeptidase Using S-Adenosyl-L-Methionine Synthetase

James D. Whiteaker, A. Shapiro, G. Walkup, 2011, Journal of biomolecular screening.