Hong Wan

发表

High Throughput Screening of Drug‐Protein Binding in Drug Discovery

Fredrik Bergström, F. Bergström, Hong Wan, 2007 .

Stability, pKa and plasma protein binding of roscovitine.

M. Vita, L. Meurling, Moustapha Hassan, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Single run measurements of drug-protein binding by high-performance frontal analysis capillary electrophoresis and mass spectrometry.

W. Lindberg, Hong Wan, A. Ostlund, 2005, Rapid communications in mass spectrometry : RCM.

Enantiomeric separation of omeprazole and its metabolite 5-hydroxyomeprazole using non-aqueous capillary electrophoresis.

L. Blomberg, Hong Wan, N. Marlin, 2006, Journal of chromatography. A.

Rapid screening of pKa values of pharmaceuticals by pressure-assisted capillary electrophoresis combined with short-end injection.

Walter Lindberg, W. Lindberg, A. Holmén, 2002, Journal of chromatography. A.

High-throughput screening of protein binding by equilibrium dialysis combined with liquid chromatography and mass spectrometry.

Hong Wan, Mikael Rehngren, Hong Wan, 2006, Journal of chromatography. A.

Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.

Susanne Winiwarter, Ulf Bredberg, Margareta Hammarlund-Udenaes, 2009, Journal of medicinal chemistry.

Measurement of Unbound Drug Exposure in Brain: Modeling of pH Partitioning Explains Diverging Results between the Brain Slice and Brain Homogenate Methods

Ulf Bredberg, Margareta Hammarlund-Udenaes, Fredrik Bergström, 2011, Drug Metabolism and Disposition.

High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.

Anders Tunek, Fabrizio Giordanetto, Fredrik Bergström, 2007, Journal of medicinal chemistry.

High-throughput pKa screening and prediction amenable for ADME profiling

Johan Ulander, J. Ulander, Hong Wan, 2006, Expert opinion on drug metabolism & toxicology.

High-throughput screening of pKa values of pharmaceuticals by pressure-assisted capillary electrophoresis and mass spectrometry.

R. A. Thompson, Walter Lindberg, W. Lindberg, 2003, Rapid communications in mass spectrometry : RCM.

Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats.

A. Plowright, Tobias Noeske, V. Schnecke, 2011, Bioorganic & medicinal chemistry.

Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.

A. Holmén, Hong Wan, Anders G Holmén, 2009, Journal of medicinal chemistry.

High throughput screening of physicochemical properties and in vitro ADME profiling in drug discovery.

A. Holmén, Hong Wan, Anders G Holmén, 2009, Combinatorial chemistry & high throughput screening.