J. Masucci

发表

Applied Pharmacokinetics in Drug Development

D. Ritchie, Zhengyin Yan, G. Leo, 2003 .

1,2,3,4-Tetrahydroquinoline-containing αvβ3 integrin antagonists with enhanced oral bioavailability

G. Leo, Dana L. Johnson, R. Kawahama, 2004 .

Small Molecule Formulation Screening Strategies in Drug Discovery

Zhengyin Yan, G. Caldwell, J. Masucci, 2014 .

Discovery of PEGylated 6-Benzhydryl-4-amino-quinazolines as Peripherally Restricted CB1R Inverse Agonists.

M. Macielag, W. Murray, K. Demarest, 2020, ACS medicinal chemistry letters.

General Guidelines for Setting Up an In Vitro LC/MS/MS Assay

G. Caldwell, J. Masucci, 2014 .

The use of the suicide CYP450 inhibitor ABT for distinguishing absorption and metabolism processes in in-vivo pharmacokinetic screens

D. Ritchie, G. Caldwell, J. Masucci, 2012, European Journal of Drug Metabolism and Pharmacokinetics.

Metabolism and excretion of the antiepileptic/antimigraine drug, topiramate in animals and humans

G. Leo, W. Wu, G. Caldwell, 2005, European Journal of Drug Metabolism and Pharmacokinetics.

Distribution and metabolism of the antipsychotic agent mazapertine succinate in rats.

G. Leo, G. Caldwell, A. Reitz, 2006, Journal of pharmaceutical and biomedical analysis.

Evaluation of the immobilized artificial membrane phosphatidylcholine. Drug discovery column for high-performance liquid chromatographic screening of drug-membrane interactions.

G. Caldwell, J. Masucci, M. Evangelisto, 1998, Journal of chromatography. A.

Cone voltage induced in-source dissociation of glucuronides in electrospray and implications in biological analyses.

Zhengyin Yan, G. Caldwell, J. Masucci, 2003, Rapid communications in mass spectrometry : RCM.

Discovery of PEGylated 6-Benzhydryl-4-amino-quinazolines as Peripherally Restricted CB1R Inverse Agonists.

M. Macielag, W. Murray, K. Demarest, 2020, ACS medicinal chemistry letters.

DMD # 9274 1 N-Glucuronidation of the PDGF Receptor Tyrosine Kinase Inhibitor 6 , 7-( Dimethoxy-2 , 4-dihydroindeno [ 1 , 2-c ] pyrazol-3-yl )-( 3-fluoro-phenyl )-amine by Human UDP-Glucuronosyltransferases

C. Ho, G. Leo, D. Johnson, 2006 .

N-GLUCURONIDATION OF THE PLATELET-DERIVED GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITOR 6,7-(DIMETHOXY-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)-(3-FLUORO-PHENYL)-AMINE BY HUMAN UDP-GLUCURONOSYLTRANSFERASES

C. Ho, G. Leo, D. Johnson, 2006, Drug Metabolism and Disposition.

Using capillary electrophoresis/frontal analysis to screen drugs interacting with human serum proteins

G. Caldwell, J. Masucci, P. McDonnell, 1998, Electrophoresis.

Comparison of the retention behavior of beta-blockers using immobilized artificial membrane chromatography and lysophospholipid micellar electrokinetic chromatography.

J. Foley, G. Caldwell, J. Masucci, 1998, Journal of chromatography. A.

Rapidly distinguishing reversible and irreversible CYP450 inhibitors by using fluorometric kinetic analyses

G. Caldwell, J. Masucci, Z. Yan, 2002, European Journal of Drug Metabolism and Pharmacokinetics.

Using affinity capillary electrophoresis to study the interaction of the extracellular binding domain of erythropoietin receptor with peptides.

L. Jolliffe, D. Johnson, G. Caldwell, 1999, Journal of biochemical and biophysical methods.

Synthesis and biological evaluation of novel pyridazinone-based alpha4 integrin receptor antagonists.

D. Hlasta, B. Maryanoff, C. Schneider, 2006, Journal of medicinal chemistry.

Liquid chromatographic and tandem mass spectrometric assay for evaluation of in vivo inhibition of rat brain monoamine oxidases (MAO) A and B following a single dose of MAO inhibitors: application of biomarkers in drug discovery.

G. Caldwell, J. Masucci, W. Hageman, 2004, Analytical biochemistry.

Mass spectrometric determination of a novel modification of the N-terminus of histidine-tagged proteins expressed in bacteria.

Zhengyin Yan, G. Caldwell, A. August, 1999, Biochemical and biophysical research communications.

Investigation of vesicle electrokinetic chromatography as an in vitro assay for the estimation of intestinal permeability of pharmaceutical drug candidates

J. Foley, J. Masucci, R. Pascoe, 2006, Electrophoresis.

Frontiers in Drug Design and Discovery

Alberto Diaspro, Alessandra Gliozzi, Mark R. Riley, 2006 .

Structure elucidation of mercury(II) compounds by positive chemical ionization mass spectrometry

G. Caldwell, A. Reitz, J. Masucci, 1987 .

Evaluation of the excretion, and metabolism of the cardiotonic agent bemoradan in male rats and female beagle dogs

W. Wu, G. Caldwell, J. Masucci, 2001, European Journal of Drug Metabolism and Pharmacokinetics.

Evaluation of the effect of oxygen exposure on human liver microsomal metabolism of mitomycin C in the presence of glutathione using liquid chromatography-quadrupole time of flight mass spectrometry.

G. Caldwell, J. Masucci, Wensheng Lang, 2005, Analytical biochemistry.

In vitro identification of metabolic pathways and cytochrome P450 enzymes involved in the metabolism of etoperidone

Zhengyin Yan, W. Wu, G. Caldwell, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

The new pre-preclinical paradigm: compound optimization in early and late phase drug discovery.

D. Ritchie, Zhengyin Yan, G. Caldwell, 2001, Current topics in medicinal chemistry.

Negative ion chemical ionization mass spectrometry—binding of molecules to bromide and iodide anions

M. Ikonomou, G. Caldwell, J. Masucci, 1989 .

In vivo microdialysis and liquid chromatography/thermospray mass spectrometry of the novel anticonvulsant 2,3:4,5-bis-O-(1-methylethylidene)-beta-D-fructopyranose sulfamate (topiramate) in rat brain fluid.

R. Shank, G. Caldwell, J. Masucci, 1998, Journal of mass spectrometry : JMS.

Electron ionization mass spectra of novel 2,3:4,5-bis-O-(1-methylethylidene)-β―D-fructopyranose derivatives and related sugar sulfamates

S. Nortey, G. Caldwell, K. Sorgi, 1989 .

Low-resolution accurate mass measurement in self-chemical ionization mass spectrometry

G. Caldwell, J. Masucci, R. Inners, 1988 .

Production of antibacterial substances by macroalgae of the New York/New Jersey coast, USA

J. Masucci, L. H. Lee, Bonnie Lustigman, 1992, Bulletin of environmental contamination and toxicology.

Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site.

A. Gibbs, D. McComsey, B. Maryanoff, 2011, ACS medicinal chemistry letters.

Identification of two new suprofen metabolites in human urine.

W. Wu, J. Masucci, 1994, Journal of pharmaceutical and biomedical analysis.

Excretion and metabolism of the antihypertensive agent, RWJ-26240 (McN-5691) in dogs.

W. Wu, G. Caldwell, J. Carson, 1998, Drug metabolism and disposition: the biological fate of chemicals.

Prebiotic Colloidal Oat Supports the Growth of Cutaneous Commensal Bacteria Including S. epidermidis and Enhances the Production of Lactic Acid

G. Leo, J. Masucci, N. Tierney, 2021, Clinical, cosmetic and investigational dermatology.

Assessing Amino Acid Concentration Changes as a Result of Drug Dosing and Cytochrome P450 and Non-cytochrome P450-Mediated Metabolism

G. Caldwell, Kerem Bingol, J. Masucci, 2021, Methods in Pharmacology and Toxicology.

Inter-laboratory reproducibility of an untargeted metabolomics GC–MS assay for analysis of human plasma

Gary W. Caldwell, Yanping Lin, Ying Li, 2020, Scientific Reports.

In vitro permeability of eight beta-blockers through Caco-2 monolayers utilizing liquid chromatography/electrospray ionization mass spectrometry.

G. Caldwell, J. Gunnet, K. Demarest, 1998, Journal of mass spectrometry : JMS.

Application of dicyandiamide as a matrix additive in fast atom bombardment mass spectrometry

G. Caldwell, A. Reitz, J. Masucci, 1990 .

Cleaved SLPI, a novel biomarker of chymase activity

M. D'Andrea, M. Olson, S. Belkowski, 2008, Biological chemistry.

Structural basis for elastolytic substrate specificity in rodent alpha-chymases.

J. Spurlino, X. Yao, L. Kuo, 2008, The Journal of biological chemistry.

The IC50 Concept Revisited

Zhengyin Yan, G. Caldwell, J. Masucci, 2012 .

Structural Basis for Elastolytic Substrate Specificity in Rodent α-Chymases*

J. Spurlino, X. Yao, L. Kuo, 2008, Journal of Biological Chemistry.

Inter-laboratory reproducibility of an untargeted metabolomics GC–MS assay for analysis of human plasma

G. Caldwell, J. Masucci, Yanping Lin, 2020, Scientific Reports.

The IC(50) concept revisited.

Zhengyin Yan, G. Caldwell, J. Masucci, 2012, Current topics in medicinal chemistry.

Biotransformation of Geldanamycin and 17-Allylamino-17-Demethoxygeldanamycin by Human Liver Microsomes: Reductive versus Oxidative Metabolism and Implications

G. Leo, G. Caldwell, J. Masucci, 2007, Drug Metabolism and Disposition.

Simultaneously Assessing Concentration Changes in 17 Biochemical Pathways as a Result of Drug Dosing and Cytochrome P450 and Non-cytochrome P450-Mediated Metabolism: A Quasi-Untargeted Metabolomics LC/MS Assay

G. Caldwell, Kerem Bingol, J. Masucci, 2021, Methods in Pharmacology and Toxicology.

Dihydroquinone ansamycins: toward resolving the conflict between low in vitro affinity and high cellular potency of geldanamycin derivatives.

J. Marugan, H. Koblish, I. Deckman, 2006, Biochemistry.

Allometric scaling of pharmacokinetic parameters in drug discovery: Can human CL, Vss and t1/2 be predicted fromin-vivo rat data?

Gary W. Caldwell, Zhengyin Yan, G. Caldwell, 2004, European Journal of Drug Metabolism and Pharmacokinetics.

A simple method to improve spectral quality in matrix-assisted laser desorption/ionization-time-of-flight-mass spectrometric analysis by using Micro Mate labeling tape as a sample support.

G. Caldwell, J. Masucci, W. Jones, 2000, Analytical biochemistry.

Biotransformation of an antihypertensive arylalkylamine analogue in the rat.

W. Wu, G. Caldwell, J. Masucci, 1998, Xenobiotica; the fate of foreign compounds in biological systems.

Identification of four plasma metabolites of Etoperidone in dogs.

W. Wu, J. Rodgers, J. Masucci, 1995, Journal of pharmaceutical and biomedical analysis.

Evaluation of the absorption, excretion and metabolism of [14 C] etoperidone in man

W. Wu, G. Caldwell, J. Masucci, 2001, Xenobiotica; the fate of foreign compounds in biological systems.

Indirect thin-layer chromatography-fast atom bombardment and chemical ionization mass spectrometry determination of carbohydrates utilizing simple and rapid microtransfer techniques

G. Caldwell, J. Masucci, W. Jones, 1990 .

Techniques for Gas Chromatography/Mass Spectrometry

G. Caldwell, J. Masucci, 2004 .