D. Steinhuebel

发表

Convergent Kilo-Scale Synthesis of a Potent Renin Inhibitor for the Treatment of Hypertension

E. Corley, Louis-Charles Campeau, D. Gauvreau, 2011 .

Practical Synthesis of A Macrocyclic HCV Protease Inhibitor: A High-Yielding Macrolactam Formation

Paul N. Devine, D. Tellers, D. Zewge, 2014 .

Direct asymmetric reductive amination.

Takao Saito, Yong-kui Sun, D. Steinhuebel, 2009, Journal of the American Chemical Society.

Asymmetric Synthesis of a Glucagon Receptor Antagonist via Friedel–Crafts Alkylation of Indole with Chiral α-Phenyl Benzyl Cation

Jeremy P. Scott, L. Tan, R. Ball, 2012 .

Rapid construction of imidazopyridines from ortho-haloaminopyridines

D. Steinhuebel, Chaomin Li, Andrew J. Goodman, 2016 .

1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia.

J. Demartino, E. Sherer, P. Váchal, 2012, Journal of medicinal chemistry.

Synthesis of N-arylated sultams: palladium- and copper-catalyzed cross coupling of aryl halides with 1,4-butane and 1,3-propanesultams

M. Palucki, D. Steinhuebel, D. Askin, 2004 .

First Generation Process for the Preparation of the DPP-IV Inhibitor Sitagliptin

Edward J. J. Grabowski, Spencer D. Dreher, J. Armstrong, 2005 .

Synthesis and Characterization of (Aminotroponiminato)titanium(IV) Dialkyl Complexes: Control of Reactivity by Ligand Design

S. Lippard, D. Steinhuebel, 1999 .

Synthesis of Unsymmetrical Vicinal Diols Using Titanium Aminotroponiminate Alkyl Complexes

S. Lippard, D. Steinhuebel, 1999 .

Stereoselective organozinc addition reactions to 1,2-dihydropyrans for the assembly of complex pyran structures.

J. Du Bois, D. Steinhuebel, James J. Fleming, 2002, Organic letters.

Enol tosylates as viable partners in Pd-catalyzed cross-coupling reactions.

I. Davies, M. Palucki, D. Steinhuebel, 2005, The Journal of organic chemistry.

Stereoselective Enol Tosylation: Preparation of Trisubstituted α,β-Unsaturated Esters

I. Davies, D. Steinhuebel, J. Baxter, 2005 .

Discovery of 5-Amino-N-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Inhibitors of IRAK4.

T. Fischmann, M. Altman, Ruojing Yang, 2015, ACS medicinal chemistry letters.

Synthetic and Structural Studies of Titanium Aminotroponiminate Complexes.

S. Lippard, D. Steinhuebel, 1999, Inorganic chemistry.

Synthesis, characterization, and reactivity of organometallic Zr(IV) carboxylate complexes

S. Lippard, D. Steinhuebel, P. Fuhrmann, 1998 .

Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer.

Andrew M Haidle, Matthew L. Maddess, J. Cumming, 2022, Journal of medicinal chemistry.

A kinase-cGAS cascade to synthesize a therapeutic STING activator

Steven P. Miller, Paul N. Devine, Matthew L. Maddess, 2022, Nature.

Process Development and Scale-Up of a Protease Inhibitor for the Treatment of HIV Featuring the Preparation of a Neopentyl Grignard Reagent and Development of a One-Pot Curtius Reaction

W. Lew, Q. Wang, M. A. Ischay, 2022, Organic Process Research & Development.

One-step synthesis of alpha-chloro acetophenones from acid chlorides and aryl precursors.

I. Davies, M. Palucki, D. Steinhuebel, 2007, Organic letters.

Discovery of MK-4688: an Efficient Inhibitor of the HDM2-p53 Protein-Protein Interaction.

G. Scapin, M. Altman, X. Fradera, 2021, Journal of medicinal chemistry.

A practical synthesis of renin inhibitor MK-1597 (ACT-178882) via catalytic enantioselective hydrogenation and epimerization of piperidine intermediate.

Stefan Abele, E. Corley, A. Roy, 2011, The Journal of organic chemistry.

Asymmetric hydrogenation of protected allylic amines.

I. Davies, Yong-kui Sun, M. Palucki, 2010, Organic letters.

1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia.

E. Sherer, K. Chapman, M. Wyvratt, 2012, Journal of medicinal chemistry.