Jing-Mei Yuan

发表

Biphenyl/diphenyl ether renin inhibitors: filling the S1 pocket of renin via the S3 pocket.

R. Bentley, C. Doe, Suresh B. Singh, 2011, Bioorganic & medicinal chemistry letters.

Structure-based design of β-site APP cleaving enzyme 1 (BACE1) inhibitors for the treatment of Alzheimer's disease.

Shankar Venkatraman, S. Venkatraman, Suresh B. Singh, 2013, Journal of medicinal chemistry.

Synthesis of a Novel Series of Amino Acid Prodrugs Based on Thienopyridine Scaffolds and Evaluation of Their Antiplatelet Activity

Xuemin Zheng, Yuquan Li, Fancui Meng, 2018, Molecules.

Defluorinative C(sp3)-P Bond Construction for the Synthesis of Phosphorylation gem-Difluoroalkenes under Catalyst- and Oxidant-Free Conditions.

Yanmin Huang, Jing-Mei Yuan, Jun Huang, 2019, Chemistry, an Asian journal.

1-amino-4-benzylphthalazines as orally bioavailable smoothened antagonists with antitumor activity.

J. Williams, S. Peukert, R. Guo, 2009, Journal of medicinal chemistry.

Design, Synthesis, and Evaluation of New Sugar-Substituted Imidazole Derivatives as Selective c-MYC Transcription Repressors Targeting the Promoter G-Quadruplex.

Ding Li, Shuo-Bin Chen, Zhishu Huang, 2022, Journal of medicinal chemistry.

Synthesis and evaluation of anthranilamide-based derivatives as FXa inhibitors

Changjiang Huang, Ligong Chen, Fancui Meng, 2017, Oncotarget.

Arylamino containing hydroxamic acids as potent urease inhibitors for the treatment of Helicobacter pylori infection.

Shen-Zhen Ren, Hui Chen, Weiwei Ni, 2018, European journal of medicinal chemistry.

Fragment-Based Lead Generation of 5-Phenyl-1H-pyrazole-3-carboxamide Derivatives as Leads for Potent Factor Xia Inhibitors

Yongnan Xu, Xuemin Zheng, Changjiang Huang, 2018, Molecules.

Novel Anthranilamide-Based FXa Inhibitors: Drug Design, Synthesis and Biological Evaluation

Yongnan Xu, Changjiang Huang, Fancui Meng, 2016, Molecules.

Several Non-salt and Solid Thienopyridine Derivatives as Oral P2Y12 Receptor Inhibitors with Good Stability.

Wei Liu, Changjiang Huang, Yuquan Li, 2022, Bioorganic & medicinal chemistry letters.

Auricularia polytricha and Flammulina velutipes reduce liver injury in DSS-induced Inflammatory Bowel Disease by improving inflammation, oxidative stress, and apoptosis through the regulation of TLR4/NF-κB signaling pathways.

Yuting Li, Jing-Mei Yuan, Cong Zhao, 2022, The Journal of nutritional biochemistry.

Cryptolepine and aromathecin based mimics as potent G-quadruplex-binding, DNA-cleavage and anticancer agents: Design, synthesis and DNA targeting-induced apoptosis.

Xin Wei, Jing-Mei Yuan, Gui-Fa Su, 2019, European journal of medicinal chemistry.

2-Styryl-4-aminoquinazoline derivatives as potent DNA-cleavage, p53-activation and in vivo effective anticancer agents.

Xin Wei, Jing-Mei Yuan, Gui-Fa Su, 2019, European journal of medicinal chemistry.

Distinct novel quinazolinone exhibits selective inhibition in MGC-803 cancer cells by dictating mutant p53 function.

Jing-Mei Yuan, Gui-Fa Su, Guo-Hai Zhang, 2015, European journal of medicinal chemistry.

Phthalazino[1,2-b]quinazolinones as p53 Activators: Cell Cycle Arrest, Apoptotic Response and Bak-Bcl-xl Complex Reorganization in Bladder Cancer Cells.

Yan Peng, Jing-Mei Yuan, Gui-Fa Su, 2017, Journal of medicinal chemistry.

Identification of 3-(benzazol-2-yl)quinoxaline derivatives as potent anticancer compounds: Privileged structure-based design, synthesis, and bioactive evaluation in vitro and in vivo.

Jing-Mei Yuan, Gui-Fa Su, Guo-Hai Zhang, 2019, European journal of medicinal chemistry.

Characterizing the interaction modes of PAR4 receptor with agonist and antagonist by molecular simulation approach

Weiren Xu, Fancui Meng, Lida Tang, 2019, Journal of Theoretical and Computational Chemistry.

Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility.

Wei Zhao, Joan Guo, David A Claremon, 2011, ACS medicinal chemistry letters.

Effects of cholesterol on chlorzoxazone translocation across POPC bilayer

Fancui Meng, Jing-Mei Yuan, 2021, Journal of Molecular Modeling.

Synthesis and antitumor evaluation of 2,3-diarylbenzofuran derivatives on HeLa cells.

Jing-Mei Yuan, Gui-Fa Su, Cheng-Xue Pan, 2017, Bioorganic & medicinal chemistry letters.