P. Bhatia

发表

5‐Lipoxygenase Inhibitors: Synthesis and Structure‐Activity Relationships of a Series of 1‐Aryl‐2H,4H‐tetrahydro‐1,2,4‐triazin‐3‐ ones.

P. Young, B. Gunn, J. Bouska, 1997 .

Correlation between brain/plasma ratios and efficacy in neuropathic pain models of selective metabotropic glutamate receptor 1 antagonists.

Jill M. Wetter, J. Brioni, S. Baker, 2006, Bioorganic & medicinal chemistry letters.

Characterization of A-93178, an Iminoxy-Quinoline

J. Bouska, G. Carter, K. Hulkower, 1997 .

(R)-(+)-N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl- 2-propynyl]-N-hydroxyurea (ABT-761), a second-generation 5-lipoxygenase inhibitor.

J. Bouska, G. Carter, P. Bhatia, 1995, Journal of medicinal chemistry.

Synthesis of indolylalkoxyiminoalkylcarboxylates as leukotriene biosynthesis inhibitors.

J. Bouska, K. Hulkower, R. Harris, 1997, Bioorganic & medicinal chemistry.

Fatty acid amide hydrolase inhibitors display broad selectivity and inhibit multiple carboxylesterases as off-targets

J. Brioni, A. Saraf, J. Rogers, 2007, Neuropharmacology.

Synthesis and evaluation of 3-aryl piperidine analogs as potent and efficacious dopamine D4 receptor agonists.

M. Nakane, J. Brioni, R. Moreland, 2005, Bioorganic & medicinal chemistry.

Structure-activity relationships of the pyridazinone series of 5-lipoxygenase inhibitors

R. D. Dyer, P. Young, D. Albert, 1992 .

Structure-activity relationship of triazafluorenone derivatives as potent and selective mGluR1 antagonists.

Meena Patel, M. Nakane, J. Brioni, 2005, Journal of medicinal chemistry.

Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells. 1. Selective inhibition of ICAM-1 and E-selectin expression.

L. Kifle, C. McCarty, K. Marsh, 2001, Journal of medicinal chemistry.

Design of inhibitors of leukotriene biosynthesis and their therapeutic potential

J. Bouska, G. Carter, R. Harris, 1998 .

Structure-activity relationships of N-hydroxyurea 5-lipoxygenase inhibitors.

R. Maki, P. Young, J. Summers, 1997, Journal of medicinal chemistry.

Catechol O-methyltransferase. 12. Affinity labeling the active site with the oxidation products of 5,6-dihydroxyindole.

R. Borchardt, P. Bhatia, 1982, Journal of medicinal chemistry.

Symmetrical bis(heteroarylmethoxyphenyl)alkylcarboxylic acids as inhibitors of leukotriene biosynthesis.

J. Bouska, G. Carter, K. Hulkower, 2000, Journal of medicinal chemistry.

Comparison of glyceraldehyde-3-phosphate dehydrogenase and 28S-ribosomal RNA gene expression as RNA loading controls for northern blot analysis of cell lines of varying malignant potential.

W. Taylor, J. Wright, A. Greenberg, 1994, Analytical biochemistry.

Dopamine D4 receptor signaling in the rat paraventricular hypothalamic nucleus: Evidence of natural coupling involving immediate early gene induction and mitogen activated protein kinase phosphorylation

S. Otte, J. Brioni, M. Decker, 2006, Neuropharmacology.

5-Lipoxygenase inhibitors: synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones.

P. Young, B. Gunn, J. Bouska, 1996, Journal of medicinal chemistry.

Discovery of 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole (ABT-724), a dopaminergic agent with a novel mode of action for the potential treatment of erectile dysfunction.

D. Donnelly-roberts, J. Sullivan, M. Nakane, 2004, Journal of medicinal chemistry.

Dopamine D4 ligands and models of receptor activation: 2-(4-pyridin-2-ylpiperazin-1-ylmethyl)-1H-benzimidazole and related heteroarylmethylarylpiperazines exhibit a substituent effect responsible for additional efficacy tuning.

D. Donnelly-roberts, J. Sullivan, M. Nakane, 2004, Journal of medicinal chemistry.

A-1048400 is a novel, orally active, state-dependent neuronal calcium channel blocker that produces dose-dependent antinociception without altering hemodynamic function in rats.

A. Swensen, T. Neelands, T. Vortherms, 2012, Biochemical pharmacology.

Heteroarylmethoxyphenylalkoxyiminoalkylcarboxylic acids as leukotriene biosynthesis inhibitors.

J. Bouska, G. Carter, K. Hulkower, 2000, Journal of medicinal chemistry.

Synthesis and structure-activity studies on N-[5-(1H-imidazol-4-yl)-5,6,7,8-tetrahydro-1-naphthalenyl]methanesulfonamide, an imidazole-containing alpha(1A)-adrenoceptor agonist.

J. Sullivan, M. Nakane, J. Kuk, 2004, Journal of medicinal chemistry.