M. Breinig

发表

Targeting heat shock protein 90 with non‐quinone inhibitors: A novel chemotherapeutic approach in human hepatocellular carcinoma

P. Schirmacher, G. Chiosis, B. Goeppert, 2009, Hepatology.

CRISPR library designer (CLD): software for multispecies design of single guide RNA libraries

Jan Winter, Florian Heigwer, Michael Boutros, 2016, Genome Biology.

Expression and therapeutic relevance of heat-shock protein 90 in pancreatic endocrine tumors.

P. Schirmacher, J. Werner, H. Scherübl, 2012, Endocrine-related cancer.

Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation

R. Spang, M. Boutros, R. Offringa, 2022, Journal for ImmunoTherapy of Cancer.

Expression Pattern and Functional Relevance of Epidermal Growth Factor Receptor and Cyclooxygenase-2: Novel Chemotherapeutic Targets in Pancreatic Endocrine Tumors?

H. Friess, P. Schirmacher, J. Kleeff, 2009, The American Journal of Gastroenterology.

The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance

M. Boutros, S. Diederichs, Maïwen Caudron-Herger, 2017, Nucleic acids research.

A high-throughput RNAi screen for detection of immune-checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytes

M. Boutros, R. König, R. Offringa, 2015, EMBO molecular medicine.

Splicing stimulates siRNA formation at Drosophila DNA double-strand breaks

M. Boutros, H. Blum, S. Krebs, 2017, PLoS genetics.

Multiplexed orthogonal genome editing and transcriptional activation by Cas12a

Marco Breinig, Anabel Y Schweitzer, Darjus F. Tschaharganeh, 2018, Nature Methods.

Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures

Emma M Schatoff, Darjus F. Tschaharganeh, A. Ferrando, 2020, Cell reports.

Down‐regulation of tumor suppressor a kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms

C. Plass, A. Warth, P. Schirmacher, 2010, Hepatology.

A chemical–genetic interaction map of small molecules using high‐throughput imaging in cancer cells

Wolfgang Huber, Michael Boutros, Marco Breinig, 2015, Molecular systems biology.

Expression and mutational status of PDGFR in thymic tumours.

H. Dienemann, P. Schirmacher, P. Schnabel, 2009, Anticancer research.

Heat Shock Protein 90-Sheltered Overexpression of Insulin-Like Growth Factor 1 Receptor Contributes to Malignancy of Thymic Epithelial Tumors

G. Giaccone, H. Dienemann, P. Schirmacher, 2011, Clinical Cancer Research.

Optimized base editors enable efficient editing in cells, organoids and mice

Emma M Schatoff, Francisco J. Sánchez-Rivera, Darjus F. Tschaharganeh, 2018, Nature Biotechnology.

An optimized toolkit for precision base editing

Teng Han, Alyna Katti, Miguel Foronda, 2018, bioRxiv.

Differential expression of E‐prostanoid receptors in human hepatocellular carcinoma

P. Schirmacher, R. Rieker, M. Breinig, 2008, International journal of cancer.

E-TALEN: a web tool to design TALENs for genome engineering

Oliver Pelz, Florian Heigwer, Michael Boutros, 2013, Nucleic acids research.

Her2 overexpression is a rare event in anorectal melanoma

P. Schirmacher, S. Aulmann, T. Zahel, 2010, Melanoma research.

caRpools: an R package for exploratory data analysis and documentation of pooled CRISPR/Cas9 screens

Oliver Pelz, Jan Winter, Florian Heigwer, 2016, Bioinform..

Establishment, characterization and drug sensitivity testing in primary cultures of human thymoma and thymic carcinoma

H. Dienemann, P. Schirmacher, P. Lichter, 2008, International journal of cancer.

Cyclooxygenase-2 (COX-2)--a therapeutic target in liver cancer?

P. Schirmacher, M. Breinig, M. Kern, 2007, Current pharmaceutical design.

GenomeCRISPR - a database for high-throughput CRISPR/Cas9 screens

Jan Winter, Florian Heigwer, Michael Boutros, 2016, Nucleic Acids Res..

Phosphatidylinositol 4-kinase III alpha governs cytoskeletal organization for invasiveness of liver cancer cells

Darjus F. Tschaharganeh, R. Bartenschlager, V. Lohmann, 2023, bioRxiv.

Multiplexed orthogonal genome editing and transcriptional activation by Cas12a

Darjus F. Tschaharganeh, M. Breinig, Steffie Revia, 2018, Nature Methods.

Targeting heat shock protein 90 with non‐quinone inhibitors: A novel chemotherapeutic approach in human hepatocellular carcinoma

P. Schirmacher, G. Chiosis, B. Goeppert, 2009, Hepatology.

[Significance of cyclooxygenase-2 as a chemotherapeutic target in hepatocellular carcinoma].

P. Schirmacher, M. Breinig, M. A. Kern, 2007, Verhandlungen der Deutschen Gesellschaft fur Pathologie.