David J. Busch

发表

Orally active purine-based inhibitors of the heat shock protein 90.

S. Kasibhatla, A. Kamal, J. Sensintaffar, 2006, Journal of medicinal chemistry.

7'-substituted benzothiazolothio- and pyridinothiazolothio-purines as potent heat shock protein 90 inhibitors.

S. Kasibhatla, Y. Ran, A. Kamal, 2006, Journal of medicinal chemistry.

Designing lipids for selective partitioning into liquid ordered membrane domains.

G. Bachand, D. Sasaki, C. Hayden, 2015, Soft matter.

A Role for an Hsp70 Nucleotide Exchange Factor in the Regulation of Synaptic Vesicle Endocytosis

Luis E Gimenez, Paul A. Oliphint, R. Sousa, 2013, The Journal of Neuroscience.

The impact of physiological crowding on the diffusivity of membrane bound proteins.

Pengyu Y. Ren, David R. Bell, David J. Busch, 2016, Soft matter.

Intrinsically disordered proteins drive membrane curvature

M. Sherman, C. Hayden, E. Lafer, 2015, Nature Communications.

Synthesis and biological evaluation of a new class of geldanamycin derivatives as potent inhibitors of Hsp90.

A. Kamal, Lia Thao, Lin Zhang, 2004, Journal of medicinal chemistry.

Rationally designed high-affinity 2-amino-6-halopurine heat shock protein 90 inhibitors that exhibit potent antitumor activity.

S. Kasibhatla, Y. Ran, L. Fritz, 2007, Journal of medicinal chemistry.

BIIB021 is a small molecule inhibitor of the heat shock protein, Hsp90, that shows potent anti-tumor activity in preclinical models

S. Kasibhatla, Hong Zhang, A. Kamal, 2007 .

Identification of RNA Content of CHO-derived Extracellular Vesicles from a Production Process.

Z. Du, Amit Kumar, Yixiao Zhang, 2022, Journal of biotechnology.

Increased synapsin expression and neurite sprouting in lamprey brain after spinal cord injury

Paul A. Oliphint, B. Lau, Naila O. Alieva, 2011, Experimental Neurology.

Hsc70 Ameliorates the Vesicle Recycling Defects Caused by Excess α-Synuclein at Synapses

R. Sousa, J. Morgan, E. Lafer, 2019, eNeuro.

Connectosomes for Direct Molecular Delivery to the Cellular Cytoplasm.

H. Smyth, Avinash K. Gadok, S. Ferrati, 2016, Journal of the American Chemical Society.

Reducing synuclein accumulation improves neuronal survival after spinal cord injury

G. Bitan, T. Schrader, J. Morgan, 2016, Experimental Neurology.

Synuclein accumulation is associated with cell‐specific neuronal death after spinal cord injury

J. Morgan, David J. Busch, 2012, The Journal of comparative neurology.

Acute increase of α-synuclein inhibits synaptic vesicle recycling evoked during intense stimulation

W. Woods, Paul A. Oliphint, J. George, 2014, Molecular biology of the cell.

Multifunctional Transmembrane Protein Ligands for Cell-Specific Targeting of Plasma Membrane-Derived Vesicles.

David J. Busch, J. Stachowiak, Chi Zhao, 2016, Small.

BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90

S. Kasibhatla, Hong Zhang, R. Scannevin, 2009, Molecular Cancer Therapeutics.

Molecular tension in syndecan-1 is regulated by extracellular mechanical cues and fluidic shear stress.

Peter L. Voyvodic, Victoria P. Le, A. Baker, 2021, Biomaterials.

Mechanical Tension in Syndecan-1 is Regulated by Extracellular Mechanical Cues and Fluidic Shear Stress

Peter L. Voyvodic, Victoria P. Le, A. Baker, 2020, bioRxiv.

Entropic Control of Receptor Recycling Using Engineered Ligands.

Samuel A. Mihelic, M. Behar, C. Hayden, 2018, Biophysical journal.

Reducing synuclein accumulation improves neuronal survival after spinal cord injury

G. Bitan, T. Schrader, J. Morgan, 2016, Experimental Neurology.