P. Belin

发表

Aminoacyl-tRNA-Utilizing Enzymes in Natural Product Biosynthesis.

M. Moutiez, P. Belin, M. Gondry, 2017, Chemical reviews.

Flexizyme-aminoacylated shortened tRNAs demonstrate that only the aminoacylated acceptor arms of the two tRNA substrates are required for cyclodipeptide synthase activity

O. Cinquin, J. Cintrat, J. Seguin, 2020, Nucleic acids research.

The nonribosomal synthesis of diketopiperazines in tRNA-dependent cyclodipeptide synthase pathways.

J. Seguin, S. Lautru, J. Pernodet, 2012, Natural product reports.

Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases

Y. Mechulam, E. Schmitt, J. Seguin, 2014, Nature Communications.

Cyclodipeptide synthases: a promising biotechnological tool for the synthesis of diverse 2,5-diketopiperazines.

M. Moutiez, P. Belin, M. Gondry, 2020, Natural product reports.

In vivo characterization of the activities of novel cyclodipeptide oxidases: new tools for increasing chemical diversity of bioproduced 2,5-diketopiperazines in Escherichia coli

O. Lequin, L. Mathéron, M. Moutiez, 2020, Microbial Cell Factories.

A Comprehensive Overview of the Cyclodipeptide Synthase Family Enriched with the Characterization of 32 New Enzymes

J. Seguin, J. Pernodet, M. Moutiez, 2018, Front. Microbiol..

Cyclodipeptide synthases are a family of tRNA-dependent peptide bond-forming enzymes.

R. Amouroux, S. Lautru, J. Pernodet, 2009, Nature chemical biology.

Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121

O. Lequin, M. Le Du, P. Belin, 2013, The Journal of Biological Chemistry.

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis

O. Lequin, J. Charbonnier, J. Pernodet, 2009, Proceedings of the National Academy of Sciences.

Defective export in Escherichia coli caused by DsbA'-PhoA hybrid proteins whose DsbA' domain cannot fold into a conformation resistant to periplasmic proteases

P. Belin, P. Boquet, A. Guigueno, 1997, Journal of bacteriology.

Reprogramming Escherichia coli for the production of prenylated indole diketopiperazine alkaloids

O. Lequin, M. Moutiez, Isabelle Correia, 2019, Scientific Reports.

Human mismatch repair protein MSH6 contains a PWWP domain that targets double stranded DNA.

S. Zinn-Justin, B. Gilquin, I. Callebaut, 2008, Biochemistry.

Specificity determinants for the two tRNA substrates of the cyclodipeptide synthase AlbC from Streptomyces noursei

J. Seguin, M. Arthur, M. Moutiez, 2014, Nucleic acids research.

Analysis of 51 cyclodipeptide synthases reveals the basis for substrate specificity.

J. Seguin, J. Pernodet, M. Moutiez, 2015, Nature chemical biology.

The Escherichia coli dsbA gene is partly transcribed from the promoter of a weakly expressed upstream gene.

P. Belin, P. Boquet, 1994, Microbiology.

Oversynthesis of a New Escherichia coliSmall RNA Suppresses Export Toxicity of DsbA′-PhoA Unfoldable Periplasmic Proteins

P. Belin, P. Boquet, J. Dassa, 2001, Journal of bacteriology.

Dual expression system suitable for high-throughput fluorescence-based screening and production of soluble proteins.

S. Zinn-Justin, A. Ménez, J. Charbonnier, 2005, Journal of proteome research.

BgK, a disulfide-containing sea anemone toxin blocking K+ channels, can be produced in Escherichia coli cytoplasm as a functional tagged protein.

G. Mourier, A. Ménez, J. Boulain, 2004, Protein expression and purification.

A pleîotropic acid phosphatase-deficient mutant of Escherichia coli shows premature termination in the dsbA gene. Use of dsbA :: phoA furions to localize a structurally important domain in DsbA

P. Belin, P. Boquet, E. Quéméneur, 2004, Molecular and General Genetics MGG.

Incorporation of Non-canonical Amino Acids into 2,5-Diketopiperazines by Cyclodipeptide Synthases.

O. Lequin, J. Seguin, M. Moutiez, 2018, Angewandte Chemie.

Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis

J. Charbonnier, J. Seguin, J. Pernodet, 2011, Nucleic acids research.

Nonribosomal peptide synthesis in animals: the cyclodipeptide synthase of Nematostella.

J. Charbonnier, J. Seguin, J. Pernodet, 2011, Chemistry & biology.

Study of bicyclomycin biosynthesis in Streptomyces cinnamoneus by genetic and biochemical approaches

Matthieu Coupet, O. Lequin, J. Seguin, 2019, Scientific Reports.

On the role of the cis‐proline residue in the active site of DsbA

E. Stura, J. Charbonnier, M. Moutiez, 2008, Protein science : a publication of the Protein Society.

Incorporation of Non-canonical Amino Acids into 2,5-Diketopiperazines by Cyclodipeptide Synthases.

O. Lequin, J. Seguin, M. Moutiez, 2018, Angewandte Chemie.

Structural basis for partition of the cyclodipeptide synthases into two subfamilies.

Y. Mechulam, E. Schmitt, J. Seguin, 2018, Journal of structural biology.

Human mismatch repair protein MSH6 contains a PWWP domain that targets double stranded DNA.

S. Zinn-Justin, B. Gilquin, I. Callebaut, 2008, Biochemistry.

Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis

O. Lequin, J. Charbonnier, J. Pernodet, 2009, Proceedings of the National Academy of Sciences.

Expanding the diversity of diketopiperazines biosynthesized by cyclodipeptide synthases

J. Seguin, M. Moutiez, P. Belin, 2014 .

Toxicity-based selection of Escherichia coli mutants for functional recombinant protein production: application to an antibody fragment.

A. Ménez, E. Lajeunesse, J. Boulain, 2004, Protein engineering, design & selection : PEDS.