H. Sellner

发表

The discovery of novel potent trans-3,4-disubstituted pyrrolidine inhibitors of the human aspartic protease renin from in silico three-dimensional (3D) pharmacophore searches.

E. Jacoby, N. Ostermann, U. Hassiepen, 2013, Journal of medicinal chemistry.

Dendritic styryl TADDOLs as novel polymer cross‐linkers: First application in an enantioselective Et2Zn addition mediated by a polymer‐incorporated titanate. Preliminary communication

D. Seebach, H. Sellner, P. Rheiner, 1997 .

Dendritically Cross-Linking Chiral Ligands: High Stability of a Polystyrene-Bound Ti-TADDOLate Catalyst with Diffusion Control.

D. Seebach, H. Sellner, 1999, Angewandte Chemie.

trans-(3S,4S)-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part I: prime site exploration using an amino linker.

N. Ostermann, E. Francotte, C. Ehrhardt, 2015, Bioorganic & medicinal chemistry letters.

Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors.

F. Sirockin, E. Valeur, C. Wiesmann, 2018, Bioorganic & medicinal chemistry letters.

Preparation of dendritic and non-dendritic styryl-substituted Salens for cross-linking suspension copolymerization with styrene and multiple use of the corresponding Mn and Cr complexes in enantioselective epoxidations and hetero-Diels-Alder reactions.

D. Seebach, J. Karjalainen, H. Sellner, 2001, Chemistry.

Manganese distribution in polystyrene beads prepared by copolymerization with cross-linking dendritic salens using laser ablation inductively coupled plasma mass spectrometry

D. Seebach, D. Günther, K. Hametner, 2003 .

Complement factor B is critical for sub-RPE deposit accumulation in a model of Doyne honeycomb retinal dystrophy with features of age-related macular degeneration

T. Dryja, T. Rejtar, B. Jaffee, 2022, Human molecular genetics.

Excursions of Synthetic Organic Chemists to the World of Oligomers and Polymers

D. Seebach, M. Rueping, A. Beck, 2001, CHIMIA.

Preparation of Polystyrene Beads with Dendritically Embedded TADDOL and Use in Enantioselective Lewis Acid Catalysis

D. Seebach, H. Sellner, P. Rheiner, 2002 .

Synthesis, and Helix or Hairpin-Turn Secondary Structures of ‘Mixed’ α/β-Peptides Consisting of Residues with Proteinogenic Side Chains and of 2-Amino-2-methylpropanoic Acid (Aib)

B. Jaun, D. Seebach, R. Mathad, 2006 .

Synthesis, and Helix or Hairpin-Turn Secondary Structures of “Mixed” α/β-Peptides Consisting of Residues with Proteinogenic Side Chains and of 2-Amino-2-methylpropanoic Acid (Aib).

B. Jaun, D. Seebach, R. Mathad, 2006 .

Discovery of 4-((2S,4S)-4-Ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases.

Thomas M. Smith, N. Gradoux, Jian Ding, 2020, Journal of medicinal chemistry.

Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer

M. Yaffe, S. Holland, S. Ram, 2021, Cancer Immunology Research.

Small-molecule factor B inhibitor for the treatment of complement-mediated diseases

Thomas M. Smith, F. Sirockin, B. Gerhartz, 2019, Proceedings of the National Academy of Sciences.

The First Class of Small Molecules Potently Disrupting the YAP‐TEAD Interaction by Direct Competition

P. Furet, P. Chène, T. Schmelzle, 2022, ChemMedChem.

Dendritic Styryl TADDOLs as Novel Polymer Cross‐Linkers: First Application in an Enantioselective Et2Zn Addition Mediated by a Polymer‐Incorporated Titanate

D. Seebach, H. Sellner, P. Rheiner, 1998 .

Abstract LB319: IAG933, a selective and orally efficacious YAP1/WWTR1(TAZ)-panTEAD protein-protein interaction inhibitor with pre-clinical activity in monotherapy and combinations

P. Furet, F. Hofmann, Laurent Sansregret, 2023, Cancer Research.

Optimization of a Class of Dihydrobenzofurane Analogs toward Orally Efficacious YAP‐TEAD Protein‐Protein Interaction Inhibitors

P. Furet, P. Chène, T. Schmelzle, 2023, ChemMedChem.