N. Pouli

发表

NMR study of 5‐substituted pyrazolo[3,4‐c]pyridine derivatives

E. Mikros, R. Marek, Orestis Tsikouris, 2008, Magnetic resonance in chemistry : MRC.

Synthesis and free radical scavenging activity of some new spiropyranocoumarins.

I. Andreadou, P. Marakos, N. Pouli, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and Tautomerism of Substituted Pyrazolo[4,3‐c]pyrazoles

S. Kadam, R. Marek, J. Toušek, 2013 .

Synthesis and tautomerism study of 7-substituted pyrazolo[3,4-c]pyridines

E. Mikros, J. Marek, R. Marek, 2006 .

Preparation and cytotoxic activity of some new rhodomycin derivatives bearing modifications in the sugar moiety.

A. Skaltsounis, J. Florent, P. Marakos, 2002, The Journal of antibiotics.

Novel pyrazolopyridine derivatives as potential angiogenesis inhibitors: Synthesis, biological evaluation and transcriptome-based mechanistic analysis.

A. Chatziioannou, F. Kolisis, O. Papadodima, 2016, European journal of medicinal chemistry.

Design and synthesis of new pyranoxanthenones bearing a nitro group or an aminosubstituted side chain on the pyran ring. Evaluation of their growth inhibitory activity in breast cancer cells.

N. Karamanos, G. Tzanakakis, P. Marakos, 2007, European journal of medicinal chemistry.

1-Ethyl-1H-3-nitrobenzopyrano[4,3,2-cd]isoindole: a novel heterocyclic ring system bearing an unusually labile deuterium-exchangeable aromatic proton

E. Mikros, P. Marakos, N. Pouli, 2006 .

Synthesis and Pharmacological Evaluation of Novel Adenine-Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents.

A. Papapetropoulos, I. Andreadou, P. Efentakis, 2016, Journal of medicinal chemistry.

Dual A1/A3 Adenosine Receptor Antagonists: Binding Kinetics and Structure-Activity Relationship Studies Using Mutagenesis and Alchemical Binding Free Energy Calculations.

G. Ladds, A. Kolocouris, Kerry Barkan, 2022, Journal of medicinal chemistry.

Discovery of a High Affinity Adenosine A1/A3 Receptor Antagonist with a Novel 7-Amino-pyrazolo[3,4-d]pyridazine Scaffold

G. Ladds, A. Kolocouris, Kerry Barkan, 2022, ACS medicinal chemistry letters.

Synthesis of some new spiropyranoquinolines and evaluation of their free radical scavenging activity.

I. Andreadou, P. Marakos, N. Pouli, 2009, Chemical & pharmaceutical bulletin.

Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation

R. Tenta, N. Lougiakis, P. Marakos, 2021, Molecules.

Synthesis of novel xanthone and acridone carboxamides with potent antiproliferative activities

T. Efferth, D. Stravopodis, Aikaterini F. Giannopoulou, 2020 .

Antiproliferative and proapoptotic activities of pyranoxanthenones, pyranothioxanthenones and their pyrazole-fused derivatives in HL-60 cells.

A. Skaltsounis, P. Marakos, N. Pouli, 2006, Anticancer research.

Design, synthesis, and biological evaluation of new raloxifene analogues of improved antagonist activity and endometrial safety.

M. Alexis, D. Mitsiou, G. Lambrinidis, 2020, Bioorganic chemistry.

Design, synthesis and anti-HBV activity evaluation of new substituted imidazo[4,5-b]pyridines.

N. Lougiakis, P. Marakos, N. Pouli, 2020, Bioorganic chemistry.

Synthesis and antiviral activity evaluation of some new 6-substituted 3-(1-adamantyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles.

E. De Clercq, C. Pannecouque, M. Witvrouw, 2002, Farmaco.

Design, synthesis and antiproliferative activity of some new azapyranoxanthenone aminoderivatives.

D. Kletsas, H. Pratsinis, P. Marakos, 2006, European journal of medicinal chemistry.

Design, synthesis, and evaluation of the antiproliferative activity of a series of novel fused xanthenone aminoderivatives in human breast cancer cells.

G. Tzanakakis, P. Marakos, N. Pouli, 2007, Journal of medicinal chemistry.

Design, synthesis, and antiproliferative activity of some new pyrazole-fused amino derivatives of the pyranoxanthenone, pyranothioxanthenone, and pyranoacridone ring systems: a new class of cytotoxic agents.

A. Skaltsounis, H. Pratsinis, P. Magiatis, 2002, Journal of medicinal chemistry.

The synthesis of 4-deazaformycin A.

P. Marakos, N. Pouli, L. Townsend, 2003, The Journal of organic chemistry.

Design, Synthesis and Antiproliferative Activity of Some New Azapyranoxanthenone Amino Derivatives.

D. Kletsas, H. Pratsinis, P. Marakos, 2006 .

New bioactive 5-arylcarboximidamidopyrazolo[3,4-c]pyridines: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships.

D. Kletsas, H. Pratsinis, N. Lougiakis, 2021, European journal of medicinal chemistry.

Design, synthesis, and cytotoxic activity evaluation of new linear pyranoxanthone aminoderivatives

D. Kletsas, H. Pratsinis, P. Marakos, 2011 .

Synthesis and cytotoxic activity of some new azapyranoxanthenone aminoderivatives.

D. Kletsas, H. Pratsinis, P. Marakos, 2003, Bioorganic & medicinal chemistry.

Design and synthesis of some new pyranoxanthenone aminoderivatives with cytotoxic activity.

A. Skaltsounis, H. Pratsinis, P. Marakos, 2002, Bioorganic & medicinal chemistry letters.

Design and synthesis of some new pyranoxanthenones with cytotoxic activity

A. Skaltsounis, D. Caignard, P. Marakos, 2001 .

Synthesis and Conformational Analysis of Some New Pyrano[2,3-c]xanthen-7-one and Pyrano[3,2-b]xanthen-6-one Derivatives with Cytotoxic Activity

A. Skaltsounis, D. Caignard, P. Marakos, 2000 .

Fused xanthone derivatives as antiproliferative agents.

P. Marakos, N. Pouli, Nicole Pouli, 2009, Anti-cancer agents in medicinal chemistry.

Synthesis antimicrobial and antifungal activity of some new 3 substituted derivatives of 4-(2,4-dichlorophenyl)-5-adamantyl-1H-1,2,4-triazole.

P. Marakos, N. Pouli, S. Papakonstantinou-Garoufalias, 2002, Farmaco.

Design and synthesis of novel 7-aminosubstituted pyrido[2,3-b]pyrazines exhibiting anti-breast cancer activity.

V. Psycharis, C. Raptopoulou, O. Argyros, 2017, European journal of medicinal chemistry.

Structural characteristics of some mercaptoacetic acid hydrazides

E. Mikros, P. Marakos, N. Pouli, 2003 .

Design and synthesis of purine analogues as highly specific ligands for FcyB, a ubiquitous fungal nucleobase transporter.

G. Lambrinidis, D. Benaki, E. Mikros, 2016, Bioorganic & medicinal chemistry.

Design and synthesis of novel amino-substituted xanthenones and benzo[b]xanthenones: Evaluation of their antiproliferative activity and their ability to overcome multidrug resistance toward MES-SA/D × 5 cells

D. Kletsas, A. Skaltsounis, H. Pratsinis, 2006 .

Interactions of a series of novel spiropyranocoumarin derivatives with reactive oxygen species

I. Andreadou, E. Mikros, P. Marakos, 2003, The Journal of pharmacy and pharmacology.

Synthesis, conformational analysis and free radical scavenging activity of some new spiropyranoquinolinones.

I. Andreadou, E. Mikros, P. Marakos, 2003, Chemical & pharmaceutical bulletin.

Synthesis and cytotoxic activity of a new potent daunomycinone derivative.

A. Skaltsounis, H. Pratsinis, P. Marakos, 2002, Bioorganic & medicinal chemistry letters.

Structure-activity relationships in fungal nucleobases transporters as dissected by the inhibitory effects of novel purine analogues.

G. Lambrinidis, E. Mikros, G. Diallinas, 2018, European journal of medicinal chemistry.

Design and synthesis of new C-nucleosides as potential adenosine deaminase inhibitors

E. Mikros, T. Nomikos, V. Myrianthopoulos, 2010 .

Synthesis of New Imidazopyridine Nucleoside Derivatives Designed as Maribavir Analogues

G. Andrei, R. Snoeck, N. Lougiakis, 2020, Molecules.

Robust, universal biomarker assay to detect senescent cells in biological specimens

Dimitris Kletsas, Jiri Bartek, Manuel Serrano, 2016, Aging cell.

Screening of Heteroaromatic Scaffolds against Cystathionine Beta-Synthase Enables Identification of Substituted Pyrazolo[3,4-c]Pyridines as Potent and Selective Orthosteric Inhibitors

C. Vorgias, A. Papapetropoulos, E. Mikros, 2020, Molecules.

Design, synthesis and antiproliferative activity of novel aminosubstituted benzothiopyranoisoindoles.

I. Trougakos, O. Tsitsilonis, P. Marakos, 2011, Bioorganic & medicinal chemistry letters.

Novel nucleoside analogues targeting HCV replication through an NS5A‐dependent inhibition mechanism

R. Bartenschlager, Vanesa Madan, P. Marakos, 2017, Chemical biology & drug design.

Design and synthesis of new substituted pyrazolopyridines with potent antiproliferative activity.

A. Skaltsounis, R. Tenta, P. Marakos, 2020, Medicinal chemistry (Shariqah (United Arab Emirates)).

Design, synthesis and cell growth inhibitory activity of a series of novel aminosubstituted xantheno[1,2-d]imidazoles in breast cancer cells.

G. Tzanakakis, P. Marakos, N. Pouli, 2008, Bioorganic & medicinal chemistry.

Synthesis and antiproliferative activity of some novel benzo-fused imidazo[1,8]naphthyridinones.

O. Tsitsilonis, P. Samara, P. Marakos, 2015, Bioorganic & medicinal chemistry letters.

Design, synthesis, and antiproliferative activity of some novel aminosubstituted xanthenones, able to overcome multidrug resistance toward MES-SA/Dx5 cells.

D. Kletsas, A. Skaltsounis, H. Pratsinis, 2005, Bioorganic & medicinal chemistry letters.

Design, synthesis and biological evaluation of novel substituted purine isosters as EGFR kinase inhibitors, with promising pharmacokinetic profile and in vivo efficacy.

E. Mikros, V. Myrianthopoulos, T. Karampelas, 2019, European journal of medicinal chemistry.

Design, Synthesis, and Antiproliferative Activity of Some New Pyrazole‐Fused Amino Derivatives of the Pyranoxanthenone, Pyranothioxanthenone, and Pyranoacridone Ring Systems: A New Class of Cytotoxic Agents.

A. Skaltsounis, H. Pratsinis, P. Magiatis, 2002 .

Synthesis of 7-aminopyrazolo[3,4-c]pyridine as A probe for the preparation of compounds of pharmacological interest

P. Marakos, N. Pouli, L. Townsend, 2002 .

Synthesis and antiproliferative activity of substituted benzopyranoisoindoles: a new class of cytotoxic compounds.

D. Kletsas, H. Pratsinis, P. Marakos, 2006, Bioorganic & Medicinal Chemistry Letters.

Synthesis and antiviral activity evaluation of some novel acyclic C-nucleosides.

J. Balzarini, P. Marakos, N. Pouli, 2008, Chemical & pharmaceutical bulletin.