P. Ala

发表

Structural Insights into the Design of Nonpeptidic Isothiazolidinone-containing Inhibitors of Protein-tyrosine Phosphatase 1B*

Richard Wynn, Mary Becker-Pasha, R. Wynn, 2006, Journal of Biological Chemistry.

Structural Basis for Inhibition of Protein-tyrosine Phosphatase 1B by Isothiazolidinone Heterocyclic Phosphonate Mimetics*

Michael Bower, Richard Wynn, Ronald Klabe, 2006, Journal of Biological Chemistry.

Structural basis for inhibition of protein-tyrosine phosphatase 1B by isothiazolidinone heterocyclic phosphonate mimetics.

Zelda R. Wasserman, Paul J. Ala, Ronald M. Klabe, 2006 .

Isothiazolidinone heterocycles as inhibitors of protein tyrosine phosphatases: synthesis and structure-activity relationships of a peptide scaffold.

M. Bower, R. Wynn, Phillip C. C. Liu, 2006, Bioorganic & medicinal chemistry.

Antifreeze protein produced endogenously in winter rye leaves.

B. Moffatt, M. Griffith, Daniel S. C. Yang, 1992, Plant physiology.

Resistance to HIV protease inhibitors: a comparison of enzyme inhibition and antiviral potency.

L. Bacheler, J. Meek, R. Klabe, 1998, Biochemistry.

Benzothiazole benzimidazole (S)-isothiazolidinone derivatives as protein tyrosine phosphatase-1B inhibitors.

R. Wynn, Wenyu Zhu, Phillip C. C. Liu, 2007, Bioorganic & medicinal chemistry letters.

Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics.

Karl Blom, Michael Bower, James Pruitt, 2005, Journal of medicinal chemistry.

Potent benzimidazole sulfonamide protein tyrosine phosphatase 1B inhibitors containing the heterocyclic (S)-isothiazolidinone phosphotyrosine mimetic.

M. Bower, R. Wynn, Wenyu Zhu, 2006, Journal of medicinal chemistry.

The mechanism of protein crystal growth from lipid layers.

R. Kornberg, S. Darst, A. Bochkarev, 1995, Journal of molecular biology.

Molecular Recognition of Cyclic Urea HIV-1 Protease Inhibitors*

Chong-Hwan Chang, PatrickY.-S. Lam, P. Jadhav, 1998, The Journal of Biological Chemistry.

Counteracting HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with XV638 and SD146, cyclic urea amides with broad specificities.

P. Lam, P. Jadhav, C. Chang, 1998, Biochemistry.

Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors.

P. Lam, C. Hodge, C. Chang, 1997, Biochemistry.

Cyclic urea amides: HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIV.

P. Jadhav, L. Bacheler, C. Chang, 1997, Journal of medicinal chemistry.

PCAM: a multi-user facility-based protein crystallization apparatus for microgravity

John M. Rosenberg, Jean-Paul Declercq, Daniel C. Carter, 1999 .

Isothiazolidinone inhibitors of PTP1B containing imidazoles and imidazolines.

M. Bower, R. Wynn, R. Klabe, 2008, Bioorganic & medicinal chemistry letters.

The Role of Ice-Binding Proteins in Frost Tolerance of Winter Rye

M. Griffith, Daniel S. C. Yang, P. Ala, 2018 .

Single crystals of a type III antifreeze polypeptide from ocean pout.

F. Sicheri, C. Hew, Y. Xue, 1994, Journal of Molecular Biology.

The molecular basis of HIV-1 protease drug resistance

Chong-Hwan Chang, B. Korant, J. Duke, 1996 .

Molecular basis of HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with cyclic urea inhibitors.

Chong-Hwan Chang, R. Klabe, P. Ala, 1997, Biochemistry.