M. Stier

发表

Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors.

N. Powell, M. J. Ryan, E. Zhang, 2007, Bioorganic & medicinal chemistry letters.

In Vitro and In Vivo Activities of PD 0305970 and PD 0326448, New Bacterial Gyrase/Topoisomerase Inhibitors with Potent Antibacterial Activities versus Multidrug-Resistant Gram-Positive and Fastidious Organism Groups

S. Gracheck, M. Huband, E. Ellsworth, 2007, Antimicrobial Agents and Chemotherapy.

Synthesis and antibacterial activity of the C-7 side chain of 3-aminoquinazolinediones.

H. D. Showalter, M. Huband, M. Shapiro, 2008, Bioorganic & medicinal chemistry letters.

A new class of anti-HIV-1 agents targeted toward the nucleocapsid protein NCp7: the 2,2'-dithiobisbenzamides.

J. Domagala, D. Hupe, R. Schultz, 1997, Bioorganic & medicinal chemistry.

Synthesis of monofluorinated 1-(naphthalen-1-yl)piperazines

A. D. White, Douglas S. Johnson, M. Stier, 2007 .

The preparation of optically active α-amino 4H-[1,2,4]oxadiazol-5-ones from optically active α-amino acids

T. Belliotti, M. Stier, Matthew R. Johnson, 2009 .

2,2′-dithiobisbenzamides derived from α-, β- and γ-amino acids possessing anti-HIV activities: synthesis and structure–activity relationship

D. P. Mack, W. J. Turner, J. Domagala, 1998 .

Synthesis of fluorinated 1,8-naphthyridinone derivatives

A. D. White, Tingsheng Li, Douglas S. Johnson, 2007 .

The synthesis and biological evaluation of novel series of nitrile-containing fluoroquinolones as antibacterial agents.

W. Denny, S. Hagen, J. Smaill, 2007, Bioorganic & medicinal chemistry letters.

A facile synthesis of substituted 3-amino-1H-quinazoline-2,4-diones

J. Rubin, H. D. Showalter, Rajeshwar Singh, 2005 .

3-aminoquinazolinediones as a new class of antibacterial agents demonstrating excellent antibacterial activity against wild-type and multidrug resistant organisms.

J. Domagala, H. D. Showalter, J. Bronstein, 2006, Journal of medicinal chemistry.

Synthesis and structural-activity relationships of 3-hydroxyquinazoline-2,4-dione antibacterial agents.

J. Domagala, H. D. Showalter, S. Gracheck, 2004, Bioorganic & medicinal chemistry letters.

Renin inhibitors containing isosteric replacements of the amide bond connecting the P3 and P2 sites.

E. Lunney, E. Nicolaides, M. Stier, 1990, Journal of medicinal chemistry.

Synthesis and Antibacterial Activity of New Quinolones Containing a 7‐( 3‐(1‐Amino‐1‐methylethyl)‐1‐pyrrolidinyl) Moiety. Gram‐Positive Agents with Excellent Oral Activity and Low Side‐Effect Potential.

S. Hagen, J. Domagala, S. Gracheck, 1994 .

A new class of analogues of the bifunctional radiosensitizer alpha-(1-aziridinylmethyl)-2-nitro-1H-imidazole-1-ethanol (RSU 1069): the cycloalkylaziridines.

W. Leopold, J. Sebolt-Leopold, M. Suto, 1991, Journal of medicinal chemistry.

Structure-activity relationships of 3-aminoquinazolinediones, a new class of bacterial type-2 topoisomerase (DNA gyrase and topo IV) inhibitors.

J. Domagala, H. D. Showalter, S. Gracheck, 2007, Bioorganic & medicinal chemistry letters.

Synthesis of 4‐(R)‐Naphthalene‐2‐yloxy‐1‐(1‐Phenyl‐(S)‐Ethyl)‐Pyrrolidin‐3‐(R)‐ol and 4‐(S)‐Naphthalen‐2‐yloxy‐1‐(1‐Phenyl‐(S)‐Ethyl)‐Pyrrolidin‐3‐(S)‐ol: Versatile Chiral Intermediates for Synthesis

D. Holsworth, M. Stier, S. Maiti, 2004 .

Synthesis and antibacterial activity of new quinolones containing a 7-[3-(1-amino-1-methylethyl)-1-pyrrolidinyl] moiety. Gram-positive agents with excellent oral activity and low side-effect potential.

S. Hagen, J. Domagala, S. Gracheck, 1994, Journal of medicinal chemistry.

Synthesis and evaluation of alpha-[[(2-haloethyl)amino]methyl]-2- nitro-1H-imidazole-1-ethanols as prodrugs of alpha-[(1-aziridinyl)methyl]-2- nitro-1H-imidazole-1-ethanol (RSU-1069) and its analogues which are radiosensitizers and bioreductively activated cytotoxins.

G. Adams, I. Stratford, M. Threadgill, 1990, Journal of medicinal chemistry.

Stereoselective Michael additions of nitromethane yielding 3R(1S N-substituted aminoethyl)pyrrolidines

M. Suto, M. Stier, J. S. Plummer, 1993 .

Evidence for the presence of N-acetyl transferase in rat retina.

W. Lovenberg, L. Miller, M. Stier, 1980, Comparative biochemistry and physiology. C: Comparative pharmacology.

Synthesis of 3,4‐dihydro‐1(2H)‐isoquinolinonesxs

H. D. Showalter, A. Sercel, M. Stier, 2001 .

Convenient Preparation of Optically Pure 3‐Aryloxy‐pyrrolidines

J. Schwarz, M. Stier, S. Maiti, 2008 .

Synthesis of 3,4‐Dihydro‐1(2H)‐isoquinolinones.

H. D. Showalter, A. Sercel, M. Stier, 2001 .

Erratum: Synthesis of 3,4-dihydro-1(2H)-isoquinolinones (Journal of Heterocyclic Chemistry (2000) 38 (961))

H. D. Showalter, A. Sercel, M. Stier, 2001 .

Pharmacologic/pharmacokinetic evaluation of emesis induced by analogs of RSU 1069 and its control by antiemetic agents.

K. Beningo, T. Heffner, W. Elliott, 1992, International journal of radiation oncology, biology, physics.

Dual-function radiosensitizers. Alpha-[[(2-bromoethyl)amino]methyl]-2-nitro-1H-imidazole-1-ethanol and related compounds: preparation via an aziridine equivalent.

M. Suto, M. Stier, L. M. Werbel, 1991, Journal of Medicinal Chemistry.

(1R,2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production.

Danielle E. Dettling, T. R. Johnson, Mostofa A Hena, 2007, Bioorganic & medicinal chemistry letters.

Synthesis of the novel antibacterial 6,8-dihydroxy-7-propyl-9H-pyrrolo[1,2-b][1,3]-benzoxazin-9-one

J. Domagala, Rajeshwar Singh, R. Micetich, 2000 .

N-tert-Butoxycarbonyl-L-Leucinal

M. Stier, O. P. Goel, S. Kesten, 2003 .

CARDIOVASCULAR AGENTS : RENIN INHIBITORS AND FACTOR Xa INHIBITORS

R. Subedi, D. Holsworth, M. Stier, 2007 .