A. Bhargava

发表

Natural products are biologically validated starting points in structural space for compound library development: solid-phase synthesis of dysidiolide-derived phosphatase inhibitors.

H. Waldmann, O. Müller, Dirk Brohm, 2002, Angewandte Chemie.

Solid-phase synthesis of dysidiolide-derived protein phosphatase inhibitors.

H. Waldmann, O. Müller, Dirk Brohm, 2002, Journal of the American Chemical Society.

Inhibition of Hypoxia‐Induced Gene Transcription by Substituted Pyrazolyl Oxadiazoles: Initial Lead Generation and Structure–Activity Relationships

K. Thierauch, P. Ellinghaus, Susanne Greschat-Schade, 2014, ChemMedChem.

Cytogenetic studies in 77 patients with chronic lymphocytic leukemia: correlations with clinical, immunologic, and phenotypic data.

E. Henderson, J. Minowada, H. Ozer, 1984, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

1-Phenyl-5-pyrazolyl ureas: potent and selective p38 kinase inhibitors.

J. S. Johnson, T. Turner, S. Wilhelm, 2000, Bioorganic & medicinal chemistry letters.

The serum- and glucocorticoid-induced kinase is a physiological mediator of aldosterone action.

D. Pearce, J. Funder, M. Fullerton, 2001, Endocrinology.

SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport.

P. Barbry, A. C. Maiyar, G. Firestone, 2001, American journal of physiology. Renal physiology.

Microsoft Word-Manuscript.docx

K. Rajagopalan, Yanan He, Yihong Chen, 2015 .

Clonal chromosome abnormalities in patients with Waldenström's and CLL-associated macroglobulinemia: significance of trisomy 12.

E. Henderson, A. Sandberg, H. Ozer, 1983, Blood.

p38 kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas.

J. S. Johnson, S. Wilhelm, W. Scott, 2001, Bioorganic & Medicinal Chemistry Letters.

1-Phenyl-5-pyrazolyl ureas: potent and selective p38 kinase inhibitors.

J. S. Johnson, T. Turner, S. Wilhelm, 2000, Bioorganic & medicinal chemistry letters.

Monocytes from patients with osteoarthritis display increased osteoclastogenesis and bone resorption: the In Vitro Osteoclast Differentiation in Arthritis study.

S. M. Sims, Lukasz Kurgan, S. Dixon, 2013, Arthritis and rheumatism.

Evaluation of whole blood catalase estimation for diagnosis of malignancy

A. Bhargava, R. Bedwani, J. Fitzpatrick, 1981, Journal of surgical oncology.

Role of SGK in mineralocorticoid-regulated sodium transport.

O. Meijer, D. Pearce, S. Y. Chen, 2000, Kidney international.

Epithelial sodium channel regulated by aldosterone-induced protein sgk.

O. Meijer, G. Firestone, Jian Wang, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Topology, glycosylation and conformational changes in the membrane domain of the vacuolar H+‐ATPase a subunit

Yeqi Yao, M. Manolson, N. Kartner, 2013, Journal of cellular biochemistry.

c-Jun NH2-terminal kinase-2 mediates osmotic stress-induced tight junction disruption in the intestinal epithelium.

R. Rao, A. Bhargava, T. Suzuki, 2010, American journal of physiology. Gastrointestinal and liver physiology.

Regorafenib (BAY 73-4506): Antitumor and antimetastatic activities in preclinical models of colorectal cancer

A. Rosenthal, Robert Schmieder, D. Zopf, 2014, International journal of cancer.

Abstract 2337: Regorafenib (BAY 73-4506): Anti-metastatic activity in a mouse model of colorectal cancer

Robert Schmieder, D. Zopf, S. Wilhelm, 2012 .

Mammalian Diaphanous-Related Formin 1 Regulates GSK3β-Dependent Microtubule Dynamics Required for T Cell Migratory Polarization

K. Siminovitch, Wen Gao, A. Alberts, 2013, PloS one.

Phosphorylation-induced Conformational Ensemble Switching in an Intrinsically Disordered Cancer/Testis Antigen*

K. Rajagopalan, Yanan He, Yihong Chen, 2015, The Journal of Biological Chemistry.

Clinical significance of monoclonal proteins in chronic lymphocytic leukemia.

K. Foon, Z. Bernstein, A. Bhargava, 1992, Leukemia.

Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity

Luciane T. Kagohara, A. Grishaev, Yanan He, 2017, Proceedings of the National Academy of Sciences.

Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor.

S. Wilhelm, W. Scott, J. Pirro, 2002, Bioorganic & medicinal chemistry letters.

Discovery of a new class of p38 kinase inhibitors.

J. S. Johnson, S. Wilhelm, W. Scott, 2000, Bioorganic & medicinal chemistry letters.

Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation.

S. Homma, F. Sera, Wei Wu, 2017, Bioorganic & medicinal chemistry.

Registered report: Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

H. Mack, M. Anant, A. Bhargava, 2016, eLife.

Registered report: RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

S. Pelech, N. Maherali, J. Kerwin, 2016, eLife.

Osteopetrosis Mutation R444L Causes Endoplasmic Reticulum Retention and Misprocessing of Vacuolar H+-ATPase a3 Subunit*

M. Glogauer, M. Manolson, N. Kartner, 2012, The Journal of Biological Chemistry.

Subunit a 3-ATPase + Misprocessing of Vacuolar H Endoplasmic Reticulum Retention and Osteopetrosis Mutation R 444 L Causes Molecular Bases of Disease :

M. Glogauer, M. Manolson, N. Kartner, 2012 .

Pharmacologic activity and pharmacokinetics of metabolites of regorafenib in preclinical models

I. Fichtner, D. Zopf, K. Thierauch, 2016, Cancer medicine.

Discovery and parallel synthesis of a new class of cathepsin K inhibitors.

J. Dumas, J. Chen, H. Hatoum-Mokdad, 2001, Bioorganic & Medicinal Chemistry Letters.

Osteopetrosis Mutation R444L Causes Endoplasmic Reticulum Retention and Misprocessing of Vacuolar H+-ATPase a3 Subunit*

M. Glogauer, M. Manolson, N. Kartner, 2012, The Journal of Biological Chemistry.