Giulio Casi

发表

Antibody-drug conjugates: Current status and future perspectives.

Rémy Gébleux, Giulio Casi, 2016, Pharmacology & therapeutics.

Spacer length shapes drug release and therapeutic efficacy of traceless disulfide-linked ADCs targeting the tumor neovasculature

I. Jelesarov, D. Neri, G. Bernardes, 2013 .

Fucose-specific conjugation of hydrazide derivatives to a vascular-targeting monoclonal antibody in IgG format.

D. Neri, G. Bernardes, Giulio Casi, 2012, Chemical communications.

A chemically-defined trifunctional antibody-cytokine-drug conjugate with potent anti- tumor activity Running Title: An antibody-cytokine-drug conjugate with anti-tumor activity

D. Neri, T. List, Giulio Casi, 2014 .

Large Molecule Therapeutics A Chemically De fi ned Trifunctional Antibody – Cytokine – Drug Conjugate with Potent Antitumor Activity

D. Neri, T. List, Giulio Casi, 2014 .

A Chemically Defined Trifunctional Antibody–Cytokine–Drug Conjugate with Potent Antitumor Activity

D. Neri, T. List, Giulio Casi, 2014, Molecular Cancer Therapeutics.

Noninternalizing targeted cytotoxics for cancer therapy.

D. Neri, Giulio Casi, 2015, Molecular pharmaceutics.

Intramolecular addition of cysteine thiyl radicals to phenylalanine in peptides: formation of cyclohexadienyl type radicals.

W. Koppenol, C. Schöneich, T. Nauser, 2005, Chemical communications.

Site-specific chemical modification of antibody fragments using traceless cleavable linkers

D. Neri, G. Bernardes, Giulio Casi, 2013, Nature Protocols.

A traceless vascular-targeting antibody-drug conjugate for cancer therapy.

J. Scheuermann, D. Neri, G. Bernardes, 2012, Angewandte Chemie.

Antibody-Based Delivery of IL2 and Cytotoxics Eradicates Tumors in Immunocompetent Mice

D. Neri, Katrin L. Gutbrodt, Giulio Casi, 2014, Molecular Cancer Therapeutics.

Large Molecule Therapeutics Antibody-Based Delivery of IL 2 and Cytotoxics Eradicates Tumors in Immunocompetent Mice

D. Neri, Katrin L. Gutbrodt, Giulio Casi, 2014 .

3,6-dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome c release via Bax channel modulation.

B. Antonsson, Agnès Bombrun, S. Halazy, 2003, Journal of medicinal chemistry.

Curative properties of noninternalizing antibody-drug conjugates based on maytansinoids.

D. Neri, G. Bernardes, Nikolaus Krall, 2014, Cancer research.

Based on Maytansinoids Drug Conjugates − Curative Properties of Noninternalizing Antibody

D. Neri, G. Bernardes, Nikolaus Krall, 2014 .

N-Alkylation of 1H-indoles and 9H-carbazoles with alcohols

Agnès Bombrun, Giulio Casi, 2002 .

Selenoglutaredoxin as a Glutathione Peroxidase Mimic

D. Hilvert, G. Roelfes, Giulio Casi, 2008, Chembiochem : a European journal of chemical biology.

Preparation of the β3‐Homoselenocysteine Derivatives Fmoc‐β3hSec(PMB)‐OH and Boc‐β3hSec(PMB)‐OH for Solution and Solid‐Phase‐Peptide Synthesis and Selenoligation

D. Hilvert, D. Seebach, Giulio Casi, 2007 .

Convergent protein synthesis.

D. Hilvert, Giulio Casi, 2003, Current opinion in structural biology.

Reversible intramolecular hydrogen transfer between cysteine thiyl radicals and glycine and alanine in model peptides: absolute rate constants derived from pulse radiolysis and laser flash photolysis.

W. Koppenol, C. Schöneich, T. Nauser, 2008, The journal of physical chemistry. B.

Reinvestigation of a Selenopeptide with Purportedly High Glutathione Peroxidase Activity*

D. Hilvert, Giulio Casi, 2007, Journal of Biological Chemistry.

Small targeted cytotoxics from DNA-encoded chemical libraries.

Florent Samain, Giulio Casi, 2015, Current opinion in chemical biology.

Antibody-Drug Conjugates and Small Molecule-Drug Conjugates: Opportunities and Challenges for the Development of Selective Anticancer Cytotoxic Agents.

D. Neri, Giulio Casi, 2015, Journal of medicinal chemistry.

Site-specific traceless coupling of potent cytotoxic drugs to recombinant antibodies for pharmacodelivery.

Dario Neri, Jörg Scheuermann, J. Scheuermann, 2012, Journal of the American Chemical Society.

Antibody Format and Drug Release Rate Determine the Therapeutic Activity of Noninternalizing Antibody–Drug Conjugates

S. Wulhfard, D. Neri, Rémy Gébleux, 2015, Molecular Cancer Therapeutics.

Antibody-drug conjugates: basic concepts, examples and future perspectives.

D. Neri, Giulio Casi, 2012, Journal of controlled release : official journal of the Controlled Release Society.

A traceless vascular-targeting antibody-drug conjugate for cancer therapy.

D. Neri, G. Bernardes, Giulio Casi, 2012, Angewandte Chemie.

Curative properties of noninternalizing antibody-drug conjugates based on maytansinoids.

D. Neri, G. Bernardes, Giulio Casi, 2014, Cancer research.