M. Coinçon

发表

Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1

Jennifer L. Martin, C. Morton, M. Scanlon, 2017, PloS one.

Visualizing drug inhibitor binding interactions using microcrystal electron diffraction

S. Z. Fisher, Z. Fisher, X. Zou, 2020, bioRxiv.

Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases

J. Sygusch, M. Coinçon, B. Jacques, 2018, The Journal of Biological Chemistry.

Visualizing drug binding interactions using microcrystal electron diffraction

S. Z. Fisher, X. Zou, M. Clabbers, 2020, Communications Biology.

Dissecting the proton transport pathway in electrogenic Na+/H+ antiporters

P. Uzdavinys, C. von Ballmoos, M. Coinçon, 2017, Proceedings of the National Academy of Sciences.

Peptides Designed To Spatially Depict the Epstein-Barr Virus Major Virion Glycoprotein gp350 Neutralization Epitope Elicit Antibodies That Block Virus-Neutralizing Antibody 72A1 Interaction with the Native gp350 Molecule

J. Sygusch, V. Leblond, M. Coinçon, 2015, Journal of Virology.

Selective irreversible inhibition of fructose 1,6-bisphosphate aldolase from Trypanosoma brucei.

N. Chabot, P. Michels, J. Sygusch, 2006, Journal of medicinal chemistry.

Hydroxynaphthaldehyde phosphate derivatives as potent covalent Schiff base inhibitors of fructose-1,6-bisphosphate aldolase.

J. Sygusch, C. Blonski, M. Coinçon, 2005, Biochemistry.

Structure and mechanism of the mammalian fructose transporter GLUT5

S. Iwata, N. Nomura, Takuya Kobayashi, 2015, Nature.

Aldolase is essential for energy production and bridging adhesin-actin cytoskeletal interactions during parasite invasion of host cells.

L. Sibley, J. Sygusch, M. Coinçon, 2009, Cell host & microbe.

Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters

David L. Dotson, A. Cameron, P. Uzdavinys, 2016, Nature Structural &Molecular Biology.

Integrating mass spectrometry with MD simulations reveals the role of lipids in Na+/H+ antiporters

E. Marklund, C. Robinson, J. Benesch, 2017, Nature Communications.

Structural basis for the delivery of activated sialic acid into Golgi for sialyation

A. Gulati, M. Coinçon, E. Nji, 2019, bioRxiv.

Glycolytic and Non-glycolytic Functions of Mycobacterium tuberculosis Fructose-1,6-bisphosphate Aldolase, an Essential Enzyme Produced by Replicating and Non-replicating Bacilli*

Jurgen Sygusch, Sabine Ehrt, Dirk Schnappinger, 2011, The Journal of Biological Chemistry.

Identification of the binding site of Brucella VirB8 interaction inhibitors.

C. Baron, Mark A. Smith, J. Sygusch, 2012, Chemistry & biology.

Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility

Jennifer L. Martin, C. Morton, M. Scanlon, 2015, Acta crystallographica. Section D, Biological crystallography.

Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases.

Jurgen Sygusch, Mary Jackson, J. Sygusch, 2010, Journal of medicinal chemistry.

Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics.

J. Sygusch, B. Gicquel, M. Jackson, 2008, Chemistry.

Crystal Structure of Reaction Intermediates in Pyruvate Class II Aldolase

Jurgen Sygusch, J. Sygusch, S. Seah, 2012, The Journal of Biological Chemistry.

Structural basis for the delivery of activated sialic acid into Golgi for sialyation

M. Coinçon, E. Nji, A. A. Qureshi, 2019, Nature Structural & Molecular Biology.

Visualizing drug binding interactions using microcrystal electron diffraction

M. Clabbers, Hongyi Xu, S. Z. Fisher, 2020, Communications Biology.

Establishing mammalian GLUT kinetics and lipid composition influences in a reconstituted-liposome system

Jens Carlsson, M. Landreh, D. Drew, 2023, Nature communications.