Ji-Hu Zhang

发表

Mass spectrometric techniques for label-free high-throughput screening in drug discovery.

V. Kaushik, T. Roddy, B. Hubbard, 2007, Analytical chemistry.

Matrix-Based Activity Pattern Classification as a Novel Method for the Characterization of Enzyme Inhibitors Derived from High-Throughput Screening

Scott A. Busby, D. Auld, S. Busby, 2016, Journal of biomolecular screening.

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.

Sarah L. Williams, W. Sellers, F. Lombardo, 2016, Journal of medicinal chemistry.

Assay Development and Screening of Human DGAT1 Inhibitors with an LC/MS-Based Assay

D. Bojanic, W. A. Hill, T. Roddy, 2010, Journal of biomolecular screening.

Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED

P. Atadja, E. Li, D. Bussiere, 2017, PloS one.

Small-molecule WNK inhibition regulates cardiovascular and renal function.

Y. Yagi, P. Hoffmann, Mitsunori Kato, 2016, Nature chemical biology.

Development of a homogeneous, fluorescence resonance energy transfer-based in vitro recruitment assay for peroxisome proliferator-activated receptor delta via selection of active LXXLL coactivator peptides.

Katherine A. Drake, R. Harrison, Ji-Hu Zhang, 2002, Analytical biochemistry.

3,5-diarylazoles as novel and selective inhibitors of protein kinase D.

I. Enyedy, T. McKinsey, N. Pagratis, 2011, Bioorganic & medicinal chemistry letters.

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.

Sarah L. Williams, W. Sellers, Z. Deng, 2020, Journal of medicinal chemistry.

Identification of orally available naphthyridine protein kinase D inhibitors.

I. Enyedy, T. McKinsey, Margaret R Pancost, 2010, Journal of medicinal chemistry.

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

Ping Zhu, Gang Liu, Peter Fekkes, 2016, Nature.

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

Thomas D. Y. Chung, Kevin R. Oldenburg, Ji-Hu Zhang, 1999, Journal of biomolecular screening.

Further Comparison of Primary Hit Identification by Different Assay Technologies and Effects of Assay Measurement Variability

Ji-Hu Zhang, Xiang Wu, Xiang Wu, 2005, Journal of biomolecular screening.

Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation

P. Atadja, E. Li, S. Chuai, 2012, Proceedings of the National Academy of Sciences.

Ligand and coactivator recruitment preferences of peroxisome proliferator activated receptor α

B. Selling, R. Wynn, P. Young, 2002, The Journal of Steroid Biochemistry and Molecular Biology.

A sensitive, homogeneous, and high-throughput assay for lysine-specific histone demethylases at the H3K4 site.

W. A. Hill, D. Auld, Z. Kang, 2012, Assay and drug development technologies.

Assay Miniaturization for Ultra-High Throughput Screening of Combinatorial and Discrete Compound Libraries: A 9600-Well (0.2 Microliter) Assay System

Thomas D.Y. Chung, Kevin R. Oldenburg, Ji-Hu Zhang, 1998 .

Assay Miniaturization: Developing Technologies and Assay Formats

I. Kariv, T. Chung, K. Oldenburg, 2001 .

Discovery and Characterization of Allosteric WNK Kinase Inhibitors.

Z. Deng, Y. Yagi, Mitsunori Kato, 2016, ACS chemical biology.

Compound Set Enrichment: A Novel Approach to Analysis of Primary HTS Data

Peter Ertl, Ansgar Schuffenhauer, Christian N. Parker, 2010, J. Chem. Inf. Model..

Evaluation of Division-Arrested Cells for Cell-Based High-Throughput Screening and Profiling

Ji-Hu Zhang, Mary Ellen Digan, Chantevy Pou, 2005, Journal of biomolecular screening.

Application of Titration-Based Screening for the Rapid Pilot Testing of High-Throughput Assays

Ji-Hu Zhang, Scott Bowes, Zhao B Kang, 2014, Journal of biomolecular screening.

Confirmation of primary active substances from high throughput screening of chemical and biological populations: a statistical approach and practical considerations.

J H Zhang, T. Chung, K. Oldenburg, 2000, Journal of combinatorial chemistry.

A high-throughput homogeneous assay for reverse transcriptase using generic reagents and time-resolved fluorescence detection.

K. Oldenburg, Ji-Hu Zhang, S. Nguyen, 2000, Analytical biochemistry.

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.

Sarah L. Williams, W. Sellers, F. Lombardo, 2016, Journal of medicinal chemistry.

Compound Set Enrichment: A Novel Approach to Analysis of Primary HTS Data

P. Raman, A. Schuffenhauer, P. Ertl, 2010, J. Chem. Inf. Model..