H. Tran

发表

Altered splicing of Tau in DM1 is different from the foetal splicing process

L. Buée, N. Sergeant, M. Caillet-Boudin, 2009, FEBS letters.

Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons

B. Miller, L. Petrucelli, W. Seeley, 2013, Acta Neuropathologica.

ASO5-1 C9ORF72 Manuscript – 05Feb2021 POTENT MIXED BACKBONE ANTISENSE OLIGONUCLEOTIDE SAFELY SUPPRESSES EXPRESSION OF MUTANT C9ORF72 TRANSCRIPTS AND POLYDIPEPTIDES: FIRST IN HUMAN PILOT STUDY

Robert H. Brown, R. Bowser, D. Fabris, 2021 .

Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide

Robert H. Brown, R. Bowser, D. Fabris, 2021, Nature Medicine.

Potent Mixed Backbone Antisense Oligonucleotide Safety Suppressed Expression of Mutant C9ORF72 Transcripts and Polypeptides: First in Human Pilot Study

Robert H. Brown, R. Bowser, D. Fabris, 2021 .

Erratum to: Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons

L. Petrucelli, W. Seeley, A. Boxer, 2014, Acta Neuropathologica.

Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models

Robert H. Brown, K. Longo, J. Dodart, 2021, Nature Communications.

A Drosophila model of ALS reveals a partial loss of function of causative human PFN1 mutants

J. Landers, C. Fallini, Fen-Biao Gao, 2017, Human molecular genetics.

Excessive release of inorganic polyphosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons

Robert H. Brown, D. A. Bosco, F. González-Nilo, 2022, Neuron.

Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALS

Z. Weng, L. Petrucelli, Jill E. Moore, 2015, Neuron.

Brain pathology in myotonic dystrophy: when tauopathy meets spliceopathy and RNAopathy

L. Buée, N. Sergeant, F. Fernández-Gómez, 2013, Front. Mol. Neurosci..

Myotonic Dystrophy: an RNA Toxic Gain of Function Tauopathy?

L. Buée, N. Sergeant, D. Blum, 2019, Advances in experimental medicine and biology.

Mis-splicing of Tau exon 10 in myotonic dystrophy type 1 is reproduced by overexpression of CELF2 but not by MBNL1 silencing.

L. Buée, V. Deramecourt, N. Sergeant, 2011, Biochimica et biophysica acta.

Reversal of RNA toxicity in myotonic dystrophy via a decoy RNA-binding protein with high affinity for expanded CUG repeats

A. Sureau, L. Buée, J. Marie, 2022, Nature Biomedical Engineering.

Analysis of Exonic Regions Involved in Nuclear Localization, Splicing Activity, and Dimerization of Muscleblind-like-1 Isoforms*

L. Buée, D. Furling, N. Sergeant, 2011, The Journal of Biological Chemistry.

Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice

H. Horvitz, Robert H. Brown, L. Petrucelli, 2015, Neuron.

Consensus brain-derived protein, extraction protocol for the study of human and murine brain proteome using both 2D-DIGE and mini 2DE immunoblotting.

L. Buée, V. Deramecourt, N. Sergeant, 2014, Journal of visualized experiments : JoVE.

Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons

L. Petrucelli, A. Karydas, Dejun Yang, 2016, Neuron.

Reversal of RNA toxicity in myotonic dystrophy via a decoy RNA-binding protein with high affinity for expanded CUG repeats

A. Sureau, J. Marie, D. Furling, 2022, Nature Biomedical Engineering.

Overexpression of MBNL1 fetal isoforms and modified splicing of Tau in the DM1 brain: Two individual consequences of CUG trinucleotide repeats

T. Cooper, A. Delacourte, L. Buée, 2008, Experimental Neurology.