J. Jonkman

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Therapeutic consequences of drug interactions with theophylline pharmacokinetics.

J. Jonkman, 1986, The Journal of allergy and clinical immunology.

An automated analytical method for the determination of felbamate in human plasma by robotic sample preparation and reversed-phase high performance liquid chromatography.

J Hempenius, J H Jonkman, G Hendriks, 1994, Journal of pharmaceutical and biomedical analysis.

Chronopharmacokinetics of theophylline after sustained release and intravenous administration to adults

L. Balant, J. Jonkman, W. V. D. Boon, 2004, European Journal of Clinical Pharmacology.

'High throughput' solid-phase extraction technology and turbo ionspray LC-MS-MS applied to the determination of haloperidol in human plasma.

J. Wieling, J. Jonkman, J. Hempenius, 1999, Journal of pharmaceutical and biomedical analysis.

Protective effect of oral oxyphenonium bromide, terbutaline and theophylline against the bronchial obstructive effects of inhaled histamine, acetylcholine and propranolol

R. A. Zeeuw, H. Sluiter, H. Meurs, 2004, European Journal of Clinical Pharmacology.

Pharmacokinetic studies in healthy volunteers in the context of in vitro/in vivo correlations

B. Oosterhuis, J. H. G. Jonkman, J. Jonkman, 2011, European Journal of Drug Metabolism and Pharmacokinetics.

Pharmacokinetic Drug Interactions with Theophylline

R. Upton, J. Jonkman, J. Jonkman, 1984, Clinical pharmacokinetics.

Food Interactions with Sustained-Release Theophylline Preparations

J. Jonkman, 1989, Clinical pharmacokinetics.

Bioequivalence studies: single vs multiple dose.

V. Steinijans, H. Blume, J. Jonkman, 1989, International journal of clinical pharmacology, therapy, and toxicology.

Food reduces the rate but not the extent of the absorption of theophylline from an aqueous solution

L. Balant, J. Jonkman, W. V. D. Boon, 2004, European Journal of Clinical Pharmacology.

Chemometrics in bioanalytical sample preparation. A fractionated combined mixture and factorial design for the modelling of the recovery of five tricyclic amines from plasma after liquid-liquid extraction prior to high-performance liquid chromatography.

C. Duineveld, J. Wieling, P. Coenegracht, 1993, Journal of chromatography.

Minor effect of multiple dose omeprazole on the pharmacokinetics of digoxin after a single oral dose.

T. Andersson, J. Jonkman, J. Jonkman, 1991, British journal of clinical pharmacology.

No Influence of Single Intravenous Doses of Omeprazole on Theophylline Elimination Kinetics

T. Andersson, J. Jonkman, T. Andersson, 1992, Journal of clinical pharmacology.

The prevalence of CYP2D6 and CYP2C19 genotypes in a population of healthy Dutch volunteers

R. A. Zeeuw, J. Jonkman, J. Jonkman, 2001, European Journal of Clinical Pharmacology.

CYP2D6 and CYP2C19 activity in a large population of Dutch healthy volunteers: indications for oral contraceptive-related gender differences

R. A. Zeeuw, B. Wilffert, J. Wieling, 1999, European Journal of Clinical Pharmacology.

A combined single and multiple dose pharmacokinetic study of oral isosorbide‐5‐mononitrate in healthy volunteers

A. Wittebrood, A. D. de Jong, J. Bron, 1991, Biopharmaceutics & drug disposition.

A Pharmacokinetic and Pharmacodynamic Comparison of Metoprolol CR/ZOK with a Conventional Slow Release Preparation

J. Jonkman, B. Oosterhuis, F. Sollie, 1990, Journal of clinical pharmacology.

Food interactions with once-a-day theophylline preparations: a review.

J. Jonkman, 1987, Chronobiology international.

Theophylline-terbutaline, a steady state study on possible pharmacokinetic interactions with special reference to chronopharmacokinetic aspects.

O. D. de Noord, L. Borgström, J. Jonkman, 1988, British journal of clinical pharmacology.

The pharmacokinetics of theophylline and enprofylline in patients with liver cirrhosis and in patients with chronic renal disease

R. A. Zeeuw, P. Jong, C. Gips, 2004, European Journal of Clinical Pharmacology.

Abstracts of papers clinical pharmacological meeting

D. J. Veldhuisen, J. Remon, J. Ottervanger, 2005, Pharmacy World and Science.

Comparison of the urinary metabolite profile of caffeine in young and elderly males.

J. Blanchard, D. Tang-Liu, J. Jonkman, 1985, British journal of clinical pharmacology.

Measurement of excretion characteristics of theophylline and its major metabolites

S. Riegelman, R. Upton, J. Jonkman, 2004, European Journal of Clinical Pharmacology.

The influence of caffeine on the steady‐state pharmacokinetics of theophylline

V. Steinijans, J. Jonkman, R. Sauter, 1991, Clinical pharmacology and therapeutics.

Effects of alpha-interferon on theophylline pharmacokinetics and metabolism.

O. D. de Noord, K. Nicholson, M. Eckert, 1989, British journal of clinical pharmacology.

Pharmacokinetics of sustained release theophylline in low and high multidose regimens.

J. Jonkman, G. Koëter, R. D. de Zeeuw, 1981, British journal of clinical pharmacology.

Effect of theophylline and enprofylline on bronchial hyperresponsiveness.

T. W. van der Mark, J. Kraan, M. Boorsma, 1989, Thorax.

Dosing time and sex-related differences in the pharmacokinetics of cefodizime and in the circadian cortisol rhythm.

A. Reinberg, F. Lévi, F. Dammacco, 1988, Chronobiologia.

Comparison of the in vitro dissolution properties and in vivo steady-state pharmacokinetics of two sustained-release theophylline preparations

J. Jonkman, W. V. D. Boon, G. Grasmeijer, 1988, Pharmaceutisch Weekblad.

Rapid and selective theophylline serum and saliva assay by means of high pressure liquid chromatography

R. A. Zeeuw, J. Jonkman, R. Schoenmaker, 1980, Pharmaceutisch Weekblad.

Abstracts of Dutch doctoral theses

R. A. Zeeuw, G. J. Jong, M. J. M. Zeeland, 2005, Pharmaceutisch Weekblad.

High-throughput solid-phase extraction for the determination of cimetidine in human plasma.

F. Maris, J. Wieling, J. Jonkman, 1998, Journal of chromatography. B, Biomedical sciences and applications.

SELECTION OF ROBUST COMBINATIONS OF EXTRACTION LIQUID COMPOSITION AND INTERNAL STANDARD - MONTE-CARLO SIMULATION OF IMPROVEMENT OF ASSAY-METHODS WITH LIQUID-LIQUID-EXTRACTION PRIOR TO HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

J. Wieling, P. Coenegracht, J. Jonkman, 1992 .

High-performance liquid chromatographic determination of reproterol in plasma using on-line trace enrichment and amperometric detection with a rotating working electrode.

R. Hageman, J. Jonkman, R. D. de Zeeuw, 1983, Journal of chromatography.

Hepatic disposition and biliary excretion of the organic cations thiazinamium and thiazinamium sulfoxide in rats.

J. Jonkman, K. Neef, D. K. Meijer, 1978, Journal of pharmaceutical sciences.

Mephenytoin as a probe for CYP2C19 phenotyping:effect of sample storage, intra-individual reproducibility and occurrence of adverse events.

D. Touw, J. Wieling, J. Jonkman, 2001, British journal of clinical pharmacology.

Pharmacokinetics of [14C]-labelled losigamone and enantiomers after oral administration to healthy subjects

J. Wieling, J. Jonkman, P. Peeters, 2010, European Journal of Drug Metabolism and Pharmacokinetics.

Determination of pilocarpine, isopilocarpine, pilocarpic acid and isopilocarpic acid in human plasma and urine by high-performance liquid chromatography with tandem mass spectrometric detection.

N. C. van de Merbel, A. Tinke, J. Jonkman, 1998, Journal of chromatography. B, Biomedical sciences and applications.

Omeprazole: pharmacology, pharmacokinetics and interactions.

J. Jonkman, B. Oosterhuis, 1989, Digestion.

Creation of four consecutive instantaneous steady-state plasma concentration plateaus of theophylline and enprofylline by repeated infusions with exponentially decreasing delivery rates

O. E. Noord, L. Borgström, J. Kraan, 2004, European Journal of Clinical Pharmacology.

Determination of oxyphenonium bromide in plasma and urine by means of ion-pair extraction, derivatization and gas chromatography-electron-capture detection.

J. Jonkman, R. D. de Zeeuw, N. Orie, 1977, Journal of chromatography.

Greatly enhanced bioavailability of theophylline on postprandial administration of a sustained release tablet

J. H. G. Jonkman, J. Jonkman, M. Lagas, 2004, European Journal of Clinical Pharmacology.

Non-reproducible serum concentration-time profiles after intake of a new sustained-release theophylline tablet

J. Jonkman, R. Schoenmaker, W. Berg, 1982 .

A new in vitro dissolution test for controlled-release theophylline tablets

R. A. Zeeuw, J. Jonkman, R. Schoenmaker, 1981 .

BIOAVAILABILITY AFTER RECTAL ADMINISTRATION OF THIAZINAMIUM METHYLSULFATE IN DIFFERENT VEHICULES

J. Jonkman, J. Wijsbeek, R. Dezeeuw, 1979 .

Fatale theofylline-intoxicaties na foutieve intraveneuze dosering

J. Jonkman, G. Koëter, 1980, Pharmaceutisch Weekblad.

A rapid thin layer chromatographic procedure to identify poor and extensive oxidative drug metabolizers in man using dextromethorphan.

J. Jonkman, J. Franke, R. D. de Zeeuw, 1992, Die Pharmazie.

Determination of Debrisoquine and 4-Hydroxydebrisoquine in Human Urine by High Performance Liquid Chromatography and Fluorescence Detection

J. Jonkman, J. Hempenius, C. Mensink, 1990 .

Subject Index, Vol. 44, Supplement 1, 1989

S. Meuwissen, P. Snel, A. Depla, 1989 .

Percutaneous absorption, metabolic profiling, and excretion of the penetration enhancer azone after multiple dosing of an azone-containing triamcinolone acetonide cream in humans.

B. Drenth, J. Wiechers, J. Jonkman, 1990, Journal of pharmaceutical sciences.

A study comparing biopharmaceutic characteristics of four once daily controlled release diltiazem preparations

G. Bianchetti, P. Dogterom, J. Jonkman, 1998, Fundamental & clinical pharmacology.

Determination of ibuprofen in human plasma by solid phase extraction and reversed-phase high-performance liquid chromatography.

J. Jonkman, J. Hempenius, R. Schoenmaker, 1985, Journal of Pharmaceutical and Biomedical Analysis.

UNALTERED IBUPROFEN-INDUCED FAECAL BLOOD LOSS UPON COADMINISTRATION OF MOCLOBEMIDE

J. Dingemanse, M. Schmitt, J. Jonkman, 1992, Drug metabolism and drug interactions.

Whole body distribution of the quaternary ammonium compound thiazinamium (N-methylpromethazine) and promethazine in monkey and mice.

J. Jonkman, H. Westenberg, N. V. Rijntjes, 1983, Arzneimittel-Forschung.

Food and a sustained release theophylline tablet on chronic dosing: bioavailability, peak-trough and trough-trough differences

J. Jonkman, M. Lagas, 1985, Pharmaceutisch Weekblad.

Studies on the Delivery Mechanisms of Theophylline from a Sustained Release Tablet

J. Jonkman, M. Lagas, 1986 .

Determination of amoxycillin in plasma by ion pair column extraction and reversed-phase ion pair high-performance liquid chromatography.

J. Jonkman, J. Hempenius, R. Schoenmaker, 1985, Journal of pharmaceutical and biomedical analysis.

Pharmacokinetic and pharmacodynamic comparison of a new controlled-release formulation of metoprolol with a traditional slow-release formulation

J. Jonkman, B. Oosterhuis, F. Kerkhof, 2004, European Journal of Clinical Pharmacology.

Lack of influence of co-trimoxazole on theophylline pharmacokinetics.

J. Jonkman, J. Hempenius, R. Schoenmaker, 1985, Journal of pharmaceutical sciences.

Clinical pharmacokinetics of theophylline during co-treatment with cefaclor.

J. Jonkman, J. Hempenius, R. Schoenmaker, 1986, International journal of clinical pharmacology, therapy, and toxicology.

Disposition and clinical pharmacokinetics of microcrystalline theophylline

R. A. Zeeuw, J. Jonkman, N. Orie, 1980, European Journal of Clinical Pharmacology.

Disposition and clinical pharmacokinetics of theophylline after administration of a new sustained release tablet

R. A. Zeeuw, J. Jonkman, R. Schoenmaker, 2004, European Journal of Clinical Pharmacology.

Correlation of serum and saliva theophylline concentrations after administration of a sustained release preparation

R. A. Zeeuw, J. Jonkman, G. Koëter, 2004, European Journal of Clinical Pharmacology.

NO EFFECT OF FOOD ON SINGLE DOSE BIOAVAILABILITY OF SUSTAINED-RELEASE THEOPHYLLINE (SABIDAL) - A COMPARISON BETWEEN SABIDAL AND CHOLINE THEOPHYLLINATE SOLUTION

L. Balant, J. Jonkman, W. V. D. Boon, 1985 .

Influence of sample preparation and storage on theophylline concentrations in biological fluids

J. Jonkman, J. Franke, R. Schoenmaker, 1982 .

ABSOLUTE BIOAVAILABILITY OF MICROCRYSTALLINE THEOPHYLLINE

J. Jonkman, R. Schoenmaker, N. Orie, 1979 .

Multi-dose comparative study of microcrystalline theophylline and choline theophyllinate

J. Jonkman, N. Orie, W. Berg, 1979 .

Circadian variation in theophylline 'trough' serum concentrations [letter]

M. Smolensky, P. Scott, J. Jonkman, 1985 .

Circadian variation in theophylline 'trough' serum concentrations.

M. Smolensky, P. Scott, J. Jonkman, 1985, British journal of clinical pharmacology.

Disposition of thiazinamium in humans after administration as an ion pair

R. A. Zeeuw, J. Jonkman, J. Wijsbeek, 1979, Pharmaceutisch weekblad.

Hepatic first-pass effect of thiazinamium methylsulfate (N-methylpromethazine methylsulfate) in dogs.

J. Jonkman, H. Westenberg, E. van der Kleyn, 1981, Journal of pharmaceutical sciences.

First-pass effect after rectal administration of thiazinamium methylsulfate.

J. Jonkman, J. Wijsbeek, R. D. de Zeeuw, 1979, Journal of pharmaceutical sciences.

Determination of thiazinamium sulphoxide in urine by means of amberlite XAD-2 column chromatography and thin-layer densitometry.

J. Jonkman, J. Wijsbeek, R. D. de Zeeuw, 1976, Journal of chromatography.

Stability of theophylline in serum, plasma, and saliva stored at different temperatures.

J. Jonkman, J. Franke, R. D. de Zeeuw, 1981, Clinical chemistry.

Development of a laboratory robotic system for automated bioanalytical methods--I. The determination of theophylline in human plasma: a comparison between the robotized and manual method.

O. D. de Noord, J. Wieling, P. Coenegracht, 1990, Journal of pharmaceutical and biomedical analysis.

Rational experimental design for bioanalytical methods validation. Illustration using an assay method for total captopril in plasma.

J. Wieling, J Hempenius, J Wieling, 1996, Journal of chromatography. A.

Absorption, metabolism and excretion of a single oral dose of 14C-repaglinide during repaglinide multiple dosing

J. V. van Lier, J. Jonkman, J. Jonkman, 1999, European Journal of Clinical Pharmacology.

Clinical pharmacokinetic comparison of two indometacin containing suppositories with different vehicula.

J. Jonkman, R. Schoenmaker, A. Holtkamp, 1984, Arzneimittel-Forschung.

Single dose absorption profiles and bioavailability of two different salbutamol tablets.

J. Jonkman, H. M. Freie, W. J. van der Boon, 1986, Arzneimittel-Forschung.

Evaluation of analytical and clinical performance of a dual-probe phenotyping method for CYP2D6 polymorphism and CYP3A4 activity screening.

J. Wieling, J. Jonkman, J. Jonkman, 2000, Therapeutic drug monitoring.

Plasma indomethacin assay by reversedphase ion pair high pressure liquid chromatography

J. Jonkman, W. V. D. Boon, R. Schoenmaker, 1983, Pharmaceutisch Weekblad.

Clinical pharmacokinetics of amoxycillin and theophylline during cotreatment with both medicaments.

J. Jonkman, J. Hempenius, R. Schoenmaker, 1985, Chemotherapy.

Lack of effect of amoxicillin on theophylline pharmacokinetics.

J. Jonkman, J. Hempenius, R. Schoenmaker, 1985, British Journal of Clinical Pharmacology.

No Effect of Influenza Vaccination on Theophylline Pharmacokinetics as Studied by Ultraviolet Spectrophotometry, HPLC, and EMIT Assay Methods

J. Jonkman, B. Oosterhuis, R. D. de Zeeuw, 1988, Therapeutic drug monitoring.

LC phases improve, but not all assays do: Metformin bioanalysis revisited

J. Jonkman, B. Oosterhuis, G. Wilkens, 1998 .

Pharmacokinetics and pharmacodynamics of thiazinamium in asthmatic patients

N. Holford, P. Clements, J. Jonkman, 2004, European Journal of Clinical Pharmacology.

Clopidogrel, a novel antiplatelet agent, and digoxin: absence of pharmacodynamic and pharmacokinetic interaction.

J. Necciari, J. Dickinson, J. Jonkman, 1999, Seminars in thrombosis and hemostasis.