A. Makoff

发表

Increased RNA editing in EAAT2 pre-mRNA from amyotrophic lateral sclerosis patients: Involvement of a cryptic polyadenylation site

R. Flomen, A. Makoff, Rachel Flomen, 2011, Neuroscience Letters.

Genetics of epilepsy: epilepsy research foundation workshop report.

J. H. Cross, Michael R. Johnson, I. Scheffer, 2007, Epileptic disorders : international epilepsy journal with videotape.

Dishevelled Regulates the Metabolism of Amyloid Precursor Protein via Protein Kinase C/Mitogen-Activated Protein Kinase and c-Jun Terminal Kinase

S. Lovestone, P. Soden, T. Golde, 2001, The Journal of Neuroscience.

Idiopathic Generalized Epilepsy with Absences: Syndrome Classification

L. Nashef, A. Valentín, L. Fisniku, 2007, Epilepsia.

The –1438A/G polymorphism in the 5-hydroxytryptamine type 2A receptor gene affects promoter activity

R. Kerwin, M. Arranz, U. D'Souza, 2004, Biological Psychiatry.

Antidepressant fluoxetine enhances glucocorticoid receptor function in vitro by modulating membrane steroid transporters

R. Kerwin, C. Pariante, R. Kim, 2003, British journal of pharmacology.

The Antidepressant Clomipramine Regulates Cortisol Intracellular Concentrations and Glucocorticoid Receptor Expression in Fibroblasts and Rat Primary Neurones

R. Kerwin, C. Pariante, S. Lovestone, 2003, Neuropsychopharmacology.

Expression of Tetanus Toxin Fragment C in E. coli: Its Purification and Potential Use as a Vaccine

N. Fairweather, A. Smallwood, A. Makoff, 1989, Nature Biotechnology.

No Association of Single Nucleotide Polymorphisms in the μ‐Opioid Receptor Subunit Gene with Idiopathic Generalized Epilepsy

L. Nashef, A. Valentín, L. Fisniku, 2006, Epilepsia.

Analysis of rare copy number variation in absence epilepsies

R. Rosch, L. Nashef, A. Valentín, 2016, Neurology: Genetics.

The histamine 1 and histamine 2 receptor genes - candidates for schizophrenia and clozapine drug response

R. Kerwin, M. Arranz, D. Mancama, 2000 .

Failure to respond to treatment with typical antipsychotics is not associated with CYP2D6 ultrarapid hydroxylation.

R. Murray, D. Collier, P. Sham, 1999, British journal of clinical pharmacology.

Dissociation of an enzyme complex from Neurospora crassa. Evidence for a protease.

A. Radford, A. Makoff, 1977, Biochimica et biophysica acta.

Oral vaccination of mice against tetanus by use of a live attenuated Salmonella carrier

N. Fairweather, G. Dougan, D. Maskell, 1990, Infection and immunity.

Use of the nirB Promoter to Direct the Stable Expression of Heterologous Antigens in Salmonella Oral Vaccine Strains: Development of a Single–Dose Oral Tetanus Vaccine

I. Charles, N. Fairweather, G. Dougan, 1992, Bio/Technology.

Genetics and biochemistry of carbamoyl phosphate biosynthesis and its utilization in the pyrimidine biosynthetic pathway

A. Radford, A. Makoff, 1978, Microbiological reviews.

The location of the feedback-specific region within thePyrimidine-3 locus ofNeurospora crassa

A. Radford, A. Makoff, 1976, Molecular and General Genetics MGG.

Synthesis of tetanus toxin fragment C in insect cells by use of a baculovirus expression system

I. Charles, N. Fairweather, A. Makoff, 1991, Infection and immunity.

Synthesis ofTetanus ToxinFragment C inInsect Cells byUseofa Baculovirus Expression System

A. Makoff, 1991 .

Recombinant Bordetella pertussis pertactin (P69) from the yeast Pichia pastoris: high-level production and immunological properties.

I G Charles, I. Charles, N. Fairweather, 1991, Vaccine.

High level heterologous expression in E. coli using the anaerobically-activated nirB promoter.

I. Charles, J. G. Doyle, A. Makoff, 1991, Nucleic acids research.

A possible model for the structure of the Neurospora carbamoyl phosphate synthase-aspartate carbamoyl transferase complex enzyme

A. Radford, F. Buxton, A. Makoff, 1978, Molecular and General Genetics MGG.

4. Genetic association studies of idiopathic generalized epilepsy

L. Nashef, P. Asherson, B. Chioza, 2000 .

Breakdown of pulse-labeled ribonucleic acid and polysomes in Bacillus megaterium: actions of streptolydigin, echinomycin, and triostins.

M. Waring, A. Makoff, 1974, Molecular pharmacology.

Expression of a novel splice variant of human mGluR1 in the cerebellum

P. Emson, A. Makoff, T. Phillips, 1997, Neuroreport.

Properties of methyl acetimidate and its use as a protein-modifying reagent.

A. Malcolm, A. Makoff, 1981, The Biochemical journal.

Comparison of the amino acid sequence of the major immunogen from three serotypes of foot and mouth disease virus.

J. Boothroyd, D. Rowlands, A. Makoff, 1982, Nucleic acids research.

The copy number variant involving part of the α7 nicotinic receptor gene contains a polymorphic inversion

R. Murray, A. Davies, C. L. Cascia, 2008, European Journal of Human Genetics.

Association between the α1a calcium channel gene CACNA1A and idiopathic generalized epilepsy

L. Nashef, P. Asherson, B. Chioza, 2001, Neurology.

Association between the 2-bp deletion polymorphism in the duplicated version of the alpha7 nicotinic receptor gene and P50 sensory gating

E. Bramon, R. Murray, M. Walshe, 2012, European Journal of Human Genetics.

Evaluation of the positional candidate gene CHRNA7 at the juvenile myoclonic epilepsy locus (EJM2) on chromosome 15q13–14

D. Curtis, C. Panayiotopoulos, A. Arzimanoglou, 2002, Epilepsy Research.

Detailed analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromes

R. Flomen, A. Makoff, 2007, Genome Biology.

Risk Factors in Sudden Death in Epilepsy (SUDEP): The Quest for Mechanisms

L. Nashef, Lina Nashef, A. Makoff, 2007, Epilepsia.

Is haplotype tagging the panacea to association mapping studies?

P. Sham, P. Asherson, A. Jawaid, 2004, European Journal of Human Genetics.

Haplotype and linkage disequilibrium analysis to characterise a region in the calcium channel gene CACNA1A associated with idiopathic generalised epilepsy

P. Sham, L. Nashef, P. Asherson, 2002, European Journal of Human Genetics.

Molecular characterization and localization of human metabotropic glutamate receptor type 3.

P. Emson, A. Makoff, K. Harrington, 1996, Brain research. Molecular brain research.

Molecular characterization and localization of human metabotropic glutamate receptor type 3.

P. Emson, A. Makoff, K. Harrington, 1996, Brain research. Molecular brain research.

Two cases of sudden unexpected death in epilepsy in a GEFS+ family with an SCN1A mutation

P. Schwartz, A. Al-Chalabi, L. Nashef, 2008, Epilepsia.

Haplotype Association Analysis of Discrete and Continuous Traits Using Mixture of Regression Models

P. Sham, D. Curtis, F. Rijsdijk, 2004, Behavior genetics.

CHRFAM7A copy number and 2-bp deletion polymorphisms and antisaccade performance.

D. Collier, V. Kumari, U. Ettinger, 2009, The international journal of neuropsychopharmacology.

Association between the alpha(1a) calcium channel gene CACNA1A and idiopathic generalized epilepsy.

P. Sham, L. Nashef, P. Asherson, 2001, Neurology.

Expression of tetanus toxin fragment C in yeast: gene synthesis is required to eliminate fortuitous polyadenylation sites in AT-rich DNA.

N. Fairweather, M. Romanos, A. Makoff, 1991, Nucleic acids research.

Linkage and association analysis of CACNG 3 in childhood absence epilepsy

P. McKeigue, J. Aicardi, A. Heils, 2008 .

Linkage and association analysis of CACNG3 in childhood absence epilepsy

P. McKeigue, J. Aicardi, A. Heils, 2007, European Journal of Human Genetics.

CACNA1A and P/Q-type calcium channels in epilepsy

L. Nashef, B. Chioza, A. Makoff, 2002, The Lancet.

Dopamine D4 Receptors

D. Collier, R. Kerwin, A. Makoff, 1997 .

Association study of dopamine receptor gene polymorphisms with drug-induced hallucinations in patients with idiopathic Parkinson's disease.

K. Aitchison, M. Arranz, R. Grünewald, 2000, Pharmacogenetics.

Polymorphisms in the genes for mGluR types 7 and 8: association studies with schizophrenia

R. Kerwin, M. Arranz, J. Munro, 2001, Schizophrenia Research.

Evidence that the N-methyl-D-aspartate subunit 1 receptor gene (GRIN1) confers susceptibility to bipolar disorder

R. Kerwin, E. Mundo, J. Kennedy, 2003, Molecular Psychiatry.

Do antidepressants regulate how cortisol affects the brain?

R. Kerwin, C. Pariante, S. Lovestone, 2004, Psychoneuroendocrinology.

Identification of a class of lysines within the non-specific DNA-binding site of RNA polymerase core enzyme from Escherichia coli.

A. Malcolm, A. Makoff, 2005, European journal of biochemistry.

Glutamine utilization in both the arginine-specific and pyrimidine-specific carbamoyl phosphate synthase enzymes of Neurospora crassa

A. Radford, A. Makoff, 1976, Molecular and General Genetics MGG.

No association found between polymorphisms in genes encoding mGluR7 and mGluR8 and idiopathic generalised epilepsy in a case control study

L. Nashef, B. Chioza, A. Makoff, 2000, Epilepsy Research.

Immunohistochemical localisation of mGluR7 protein in the rodent and human cerebellar cortex using subtype specific antibodies.

P. Emson, R. Faull, S. Rees, 1998, Brain research. Molecular brain research.

Human metabotropic glutamate receptor type 7: molecular cloning and mRNA distribution in the CNS.

P. Emson, A. Makoff, K. Harrington, 1996, Brain research. Molecular brain research.

Association of μ-opioid receptor subunit gene and idiopathic generalized epilepsy

L. Nashef, P. Asherson, B. Chioza, 2002 .

Common inversion polymorphisms and rare microdeletions at 15q13.3

R. Flomen, A. Makoff, 2009, European Journal of Human Genetics.

RNA editing of the 5-HT2C receptor is reduced in schizophrenia

Paul J. Harrison, R. Kerwin, A. Makoff, 2001, Molecular Psychiatry.

Molecular characterization and localization of human metabotropic glutamate receptor type 4.

P. Emson, A. Makoff, K. Harrington, 1996, Brain research. Molecular brain research.

Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene.

P. Sham, R. Kerwin, R. Flomen, 2004, Nucleic acids research.

Enhanced expression of recombinant proteins in insect cells using a baculovirus vector containing a bacterial leader sequence.

I. Charles, D. Gewert, M. Page, 1992, Nucleic acids research.

High level heterologous expression in E. coli using mutant forms of the lac promoter.

A. Makoff, M. Oxer, 1991, Nucleic acids research.

Cloning and sequence analysis of the glucoamylase gene of Neurospora crassa

J. H. Parish, A. Radford, A. Makoff, 1993, Current Genetics.

Expression of tetanus toxin fragment C in E. coli: high level expression by removing rare codons.

N. Fairweather, M. Romanos, A. Makoff, 1989, Nucleic acids research.

Protective Surface Antigen P69 of Bordetella pertussis: Its Characterization and Very High Level Expression in Escherichia coli

I. Charles, N. Fairweather, A. Makoff, 1990, Bio/Technology.

Molecular cloning of human GABABR1 and its tissue distribution.

A. Makoff, 1999, Brain research. Molecular brain research.

Heterologous expression in Escherichia coli : effects of alterations in the sequence 5′ to the initiation codon

A. Smallwood, A. Makoff, 1988 .

Polymorphism analysis of JRK/JH8, the human homologue of mouse jerky, and description of a rare mutation in a case of CAE evolving to JME

P. Froguel, L. Nashef, P. Asherson, 2001, Epilepsy Research.

Association study of CHRFAM7A copy number and 2bp deletion polymorphisms with schizophrenia and bipolar affective disorder

D. Collier, G. Breen, D. St. Clair, 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Antidepressants enhance glucocorticoid receptor function in vitro by modulating the membrane steroid transporters

R. Kerwin, C. Pariante, S. Lovestone, 2001, British journal of pharmacology.

The use of two-cistron constructions in improving the expression of a heterologous gene in E. coli.

A. Smallwood, A. Makoff, 1990, Nucleic acids research.

Do antidepressants regulate how cortisol affects the brain?

R. Kerwin, C. Pariante, S. Lovestone, 2004, Psychoneuroendocrinology.

Localization of mGluR4 protein in the rat cerebral cortex and hippocampus

P. Emson, A. Makoff, Susan Brown, 1997, Neuroreport.

Suggestive evidence for association of two potassium channel genes with different idiopathic generalised epilepsy syndromes

L. Nashef, B. Chioza, A. Osei-Lah, 2002, Epilepsy Research.

5th International Congress of Neuroendocrinology

R. Kerwin, C. Pariante, S. Lovestone, 2002 .

Analysis of rare copy number variation in absence epilepsies

R. Rosch, D. Pal, A. Makoff, 2016 .

Characterization of the aspartate carbamoyltransferase fragment generated by protease action on the pyrimidine-3 gene product of Neurospora crassa.

A. Makoff, 1977, Biochimica et biophysica acta.