S. Danckwardt

发表

Emerging Roles of RNA 3′-end Cleavage and Polyadenylation in Pathogenesis, Diagnosis and Therapy of Human Disorders

J. Nourse, S. Spada, S. Danckwardt, 2020, Biomolecules.

A novel rationale for targeting FXI: Insights from the hemostatic miRNA targetome for emerging anticoagulant strategies.

J. Nourse, S. Danckwardt, 2020, Pharmacology & therapeutics.

A novel rationale for targeting FXI: Insights from the hemostastic miRNA targetome for emerging anticoagulant strategies

J. Nourse, S. Danckwardt, 2018, bioRxiv.

Large‐scale identification of functional microRNA targeting reveals cooperative regulation of the hemostatic system

K. Lackner, S. Hüttelmaier, J. Nourse, 2018, Journal of thrombosis and haemostasis : JTH.

Relation between platelet coagulant and vascular function, sex-specific analysis in adult survivors of childhood cancer compared to a population-based sample

P. Wild, H. ten Cate, J. Prochaska, 2019, Scientific Reports.

Glucagon‐like peptide‐1 receptor signalling reduces microvascular thrombosis, nitro‐oxidative stress and platelet activation in endotoxaemic mice

T. Münzel, S. Strand, A. Daiber, 2017, British journal of pharmacology.

PCF11 links alternative polyadenylation to formation and spontaneous regression of neuroblastoma

F. Westermann, H. Binder, B. Tian, 2018, bioRxiv.

Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma

F. Westermann, H. Binder, B. Tian, 2018, Nature Communications.

Cluster of differentiation 44 promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin

B. Bartosch, M. Giovannini, P. Herrlich, 2020, International journal of cancer.

No Evidence for Classic Thrombotic Microangiopathy in COVID-19

B. Lämmle, P. Galle, K. Lackner, 2021, Journal of clinical medicine.

3′ End Processing of the Prothrombin mRNA in Thrombophilia

M. Hentze, N. Gehring, A. Kulozik, 2006, Acta Haematologica.

TREND-DB—a transcriptome-wide atlas of the dynamic landscape of alternative polyadenylation

S. Danckwardt, Denise Scherzinger, F. Marini, 2020, bioRxiv.

The Bidirectional Link Between RNA Cleavage and Polyadenylation and Genome Stability: Recent Insights From a Systematic Screen

B. Luke, S. Danckwardt, S. Spada, 2022, Frontiers in Genetics.

Macrophage protease-activated receptor 2 regulates fetal liver erythropoiesis in mice.

W. Ruf, H. Weiler, S. Reyda, 2018, Blood advances.

The prothrombin 20209 C→T mutation in Jewish‐Moroccan Caucasians: molecular analysis of gain‐of‐function of 3′ end processing

M. Hentze, A. Kulozik, S. Danckwardt, 2006, Journal of thrombosis and haemostasis : JTH.

Dermal CD207-Negative Migratory Dendritic Cells Are Fully Competent to Prime Protective, Skin Homing Cytotoxic T-Lymphocyte Responses.

H. Schild, B. Clausen, T. Bopp, 2019, The Journal of investigative dermatology.

Pathophysiological Role and Diagnostic Potential of R-Loops in Cancer and Beyond

S. Danckwardt, Essak S. Khan, 2022, Genes.

Arginase-1 Deletion in Erythrocytes Promotes Vascular Calcification via Enhanced GSNOR (S-Nitrosoglutathione Reductase) Expression and NO Signaling in Smooth Muscle Cells

T. Münzel, P. Wenzel, S. Konstantinides, 2022, Arteriosclerosis, thrombosis, and vascular biology.

Abnormally spliced beta-globin mRNAs: a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay.

M. Hentze, G. Neu-Yilik, A. Kulozik, 2002, Blood.

Abnormally spliced b-globin mRNAs : a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay

M. Hentze, G. Neu-Yilik, A. Kulozik, 2002 .

Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells

H. Schild, O. Kretz, A. Macpherson, 2020, Cell.

Downregulation of Notch signaling by γ-secretase inhibition can abrogate chemotherapy-induced apoptosis in T-ALL cell lines

M. Muckenthaler, A. Kulozik, S. Breit, 2009, Annals of Hematology.

Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyond

M. Hentze, A. Kulozik, S. Danckwardt, 2013, Journal of Molecular Medicine.

Transcriptome 3′end organization by PCF11 links alternative polyadenylation to formation and neuronal differentiation of neuroblastoma

F. Westermann, H. Binder, B. Tian, 2018, Nature Communications.

International Journal of Molecular Sciences the Importance of Thrombin in Cerebral Injury and Disease

K. Prokai-Tatrai, O. Kempski, Viola Lorenz, 2022 .

TRENDseq-A highly multiplexed high throughput RNA 3' end sequencing for mapping alternative polyadenylation.

S. Danckwardt, A. Ogorodnikov, 2021, Methods in enzymology.

Processing and transcriptome expansion at the mRNA 3′ end in health and disease: finding the right end

S. Danckwardt, A. Ogorodnikov, Yulia Kargapolova, 2016, Pflügers Archiv - European Journal of Physiology.

3′ end mRNA processing: molecular mechanisms and implications for health and disease

M. Hentze, A. Kulozik, Andreas E Kulozik, 2008, The EMBO journal.

Focus Quality Control 3 0 end mRNA processing: molecular mechanisms and implications for health and disease

Matthias W. Hentze, M. Hentze, A. Kulozik, 2008 .

p38 MAPK controls prothrombin expression by regulated RNA 3' end processing.

M. Hentze, P. Schirmacher, M. Wilm, 2011, Molecular cell.

A non-invasive diagnostic assay for rapid detection and characterization of aberrant mRNA-splicing by nonsense mediated decay inhibition.

K. Lackner, H. Rossmann, E. Mengel, 2020, Molecular genetics and metabolism.

sCLIP—an integrated platform to study RNA–protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs

Michal Levin, K. Lackner, Yulia Kargapolova, 2017, Nucleic acids research.

Splicing factors stimulate polyadenylation via USEs at non‐canonical 3′ end formation signals

P. Bork, M. Hentze, K. U. Foerstner, 2007, The EMBO journal.

The prothrombin 3'end formation signal reveals a unique architecture that is sensitive to thrombophilic gain-of-function mutations.

M. Hentze, G. Neu-Yilik, A. Kulozik, 2004, Blood.

Non-invasive imaging of gene expression and protein secretion dynamics in living mice: identification of ectopic prothrombin expression as driver of thrombosis in cancer

K. Lackner, S. Tokalov, J. Nourse, 2021, bioRxiv.

Pathologies at the nexus of blood coagulation and inflammation: thrombin in hemostasis, cancer, and beyond

M. Hentze, A. Kulozik, S. Danckwardt, 2013, Journal of Molecular Medicine.

Post-transcriptional control of haemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disorders

D. Trégouët, S. Danckwardt, E. Castoldi, 2023, Cardiovascular research.

Processing and transcriptome expansion at the mRNA 3′ end in health and disease: finding the right end

S. Danckwardt, A. Ogorodnikov, Yulia Kargapolova, 2016, Pflügers Archiv - European Journal of Physiology.

More on: functional analysis of two prothrombin 3′‐UTR variants: the C20209T variant, mainly found among African‐Americans, and the C20209A variant

A. Kulozik, S. Danckwardt, K. Hartmann, 2006 .

The prothrombin 3’end formation signal reveals a unique architecture that is sensitive to thrombophilic gain-of-function mutations

M. Hentze, G. Neu-Yilik, A. Kulozik, 2004 .

"MicroRNAs as prognostic biomarkers for (cancer-associated) venous thromboembolism?": comment.

J. Nourse, S. Danckwardt, 2023, Journal of thrombosis and haemostasis : JTH.

transcripts sensitive and insensitive to nonsense-mediated mRNA decay -globin mRNAs: a single point mutation generates β Abnormally spliced

M. Hentze, G. Neu-Yilik, A. Kulozik, 2013 .

Macrophage protease-activated receptor 2 regulates fetal liver erythropoiesis in mice.

H. Weiler, S. Reyda, S. Danckwardt, 2020, Blood advances.

3′ end mRNA processing: molecular mechanisms and implications for health and disease

M. Hentze, A. Kulozik, S. Danckwardt, 2008, The EMBO journal.