D. Valensin

发表

Copper, zinc and iron in neurodegenerative diseases (Alzheimer's, Parkinson's and prion diseases)

Marek Luczkowski, H. Kozłowski, Daniela Valensin, 2012 .

Molecular insights to the bioactive form of BV02, a reference inhibitor of 14-3-3σ protein-protein interactions.

G. Vignaroli, M. Botta, M. Mori, 2016, Bioorganic & medicinal chemistry letters.

1H NMR studies of copper binding by histidine‐containing peptides

N. D’Amelio, D. Valensin, G. Valensin, 2003 .

Differences in the binding of copper(I) to α- and β-synuclein.

L. Bubacco, S. Mangani, L. Casella, 2015, Inorganic chemistry.

Reactivity of copper-α-synuclein peptide complexes relevant to Parkinson's disease.

E. Monzani, L. Casella, Stefania Nicolis, 2015, Metallomics : integrated biometal science.

Interaction of angiotensin II with the C-terminal 300-320 fragment of the rat angiotensin II receptor AT1a monitored by NMR.

N. D’Amelio, P. Neri, N. Gaggelli, 2003, Biopolymers.

The role of methylation in the copper(ii) coordination properties of a His-containing decapeptide.

R. Delgado, O. Iranzo, P. Mateus, 2019, Dalton transactions.

Impact of the peptide sequence on the coordination abilities of albumin-like tripeptides towards Cu2+, Ni2+ and Zn2+ ions. Potential albumin-like peptide chelators

P. Młynarz, J. Zabrocki, H. Kozłowski, 2002 .

NMR studies of the Zn2+ interactions with rat and human beta-amyloid (1-28) peptides in water-micelle environment.

E. Jankowska, H. Kozłowski, E. Wieczerzak, 2008, The journal of physical chemistry. B.

Insights into the homocoupling reaction of 4-methylamino benzoic acid mediated by Trametes versicolor laccase.

R. Basosi, R. Pogni, M. C. Baratto, 2011, Molecular bioSystems.

Structural studies in solution and in the solid state on the zinc chelate of 2-hydroxy-(4-methylthio)butanoic acid, an effective mineral supplement in animal feeding

R. Basosi, M. Parisi, A. Sinicropi, 2009 .

Binding and Reactivity of Copper to R1 and R3 Fragments of tau Protein.

M. Tegoni, E. Monzani, L. Casella, 2019, Inorganic chemistry.

A novel method for the efficient synthesis of methyl 2-oxo-2-arylacetates and its application to the preparation of fungicidal methyl (E)-O-methyloximino-2-arylacetates and their (Z)-stereoisomers

L. Mannina, R. Rossi, A. Carpita, 1999 .

Metal specificity of the Ni(II) and Zn(II) binding sites of the N-terminal and G-domain of E. coli HypB.

H. Kozłowski, M. Rowińska-Żyrek, D. Valensin, 2021, Dalton transactions.

Chiral peptide nucleic acids having thymine and adenine in their side chain as specific ligands for NiII and CuII

S. Ołdziej, H. Kozłowski, M. Taddei, 2000 .

Cu(II) ion interaction with teicoplanin-vancomycin's analog.

N. Gaggelli, M. Jeżowska‐Bojczuk, D. Valensin, 2010, Journal of inorganic biochemistry.

Unusual binding ability of vancomycin towards Cu2+ ions.

M. Światek, M. Jeżowska‐Bojczuk, D. Valensin, 2005, Dalton transactions.

How copper ions and membrane environment influence the structure of the human and chicken tandem repeats domain?

H. Kozłowski, D. Valensin, A. Hecel, 2019, Journal of inorganic biochemistry.

The complex-formation behaviour of His residues in the fifth Cu2+ binding site of human prion protein: a close look

H. Kozłowski, R. Guerrini, D. Bacco, 2009 .

Dermcidin, an anionic antimicrobial peptide: influence of lipid charge, pH and Zn2+ on its interaction with a biomimetic membrane.

L. Becucci, R. Guidelli, M. Innocenti, 2014, Soft matter.

Copper(I/II), α/β‐Synuclein and Amyloid‐β: Menage à Trois?

L. Casella, P. Faller, C. Hureau, 2015, Chembiochem : a European journal of chemical biology.

Specific metal ion binding sites in unstructured regions of proteins

H. Kozłowski, M. Rowińska-Żyrek, M. Remelli, 2013 .

Copper Binding to the Neurotoxic Peptide PrP106–126: Thermodynamic and Structural Studies

F. Mancini, H. Kozłowski, R. Guerrini, 2004, Chembiochem : a European journal of chemical biology.

Probing the role of metal ions on reversible peptide–protein interactions by NMR

F. Mancini, N. D’Amelio, N. Gaggelli, 2004 .

Remote His50 Acts as a Coordination Switch in the High-Affinity N-Terminal Centered Copper(II) Site of α-Synuclein.

L. Casella, P. Faller, C. Hureau, 2015, Inorganic chemistry.

The structure of the Ce(III)-angiotensin II complex as obtained from NMR data and molecular dynamics calculations.

F. Mancini, N. D’Amelio, N. Gaggelli, 2003, Journal of inorganic biochemistry.

DOES hemopressin bind metal ions in vivo?

S. Salvadori, H. Kozłowski, R. Guerrini, 2016, Dalton transactions.

Zn(II) ions bind very efficiently to tandem repeat region of "prion related protein" (PrP-rel-2) of zebra-fish. MS and potentiometric evidence.

E. Jankowska, H. Kozłowski, Z. Szewczuk, 2008, Dalton transactions.

Synthesis and structural characterization of a novel phenoxazinone dye by use of a fungal laccase

R. Basosi, R. Pogni, M. Taddei, 2010 .

Competition between histamine-like and poly-imidazole coordination sites for Cu(2+) and Zn(2+) ions in zebra-fish peptide of prion-like protein.

H. Kozłowski, W. Kamysz, D. Valensin, 2010, Dalton transactions.

NMR studies on Cu(II)-peptide complexes: exchange kinetics and determination of structures in solution.

H. Kozłowski, D. Valensin, G. Valensin, 2005, Molecular bioSystems.

Identification of a novel high affinity copper binding site in the APP(145-155) fragment of amyloid precursor protein.

F. Mancini, H. Kozłowski, D. Valensin, 2004, Dalton transactions.

A community-built calibration system: The case study of quantification of metabolites in grape juice by qNMR spectroscopy.

Panteleimon G. Takis, L. Goldoni, M. Assfalg, 2020, Talanta.

Fibrils of α-Synuclein Abolish the Affinity of Cu2+-Binding Site to His50 and Induce Hopping of Cu2+ Ions in the Termini.

L. Bubacco, Y. Miller, S. Mangani, 2019, Inorganic chemistry.

Interaction of the human prion PrP(106-126) sequence with copper(II), manganese(II), and zinc(II): NMR and EPR studies.

R. Pogni, H. Kozłowski, M. Remelli, 2005, Journal of the American Chemical Society.

The dimeric and tetrameric octarepeat fragments of prion protein behave differently to its monomeric unit.

F. Mancini, H. Kozłowski, K. Rolka, 2004, Dalton transactions.

Synthesis, structural characterization and LCA analysis of a novel phenoxazinone dye by use of a fungal laccase

R. Basosi, R. Pogni, A. Jarosz-Wilkołazka, 2010 .

{Ru(CO)x}-core complexes with selected azoles: Synthesis, X-ray structure, spectroscopy, DFT analysis and evaluation of cytotoxic activity against human cancer cells

M. Jakupec, B. Keppler, L. Messori, 2014 .

A New Stereocontrolled Synthesis of Dihydroxerulin, a Potent Noncytotoxic Inhibitor of the Biosynthesis of Cholesterol

L. Mannina, R. Rossi, F. Bellina, 2000 .

Copper homeostasis and neurodegenerative disorders (Alzheimer's, prion, and Parkinson's diseases and amyotrophic lateral sclerosis).

H. Kozłowski, Daniela Valensin, D. Valensin, 2006, Chemical reviews.

Copper chelators: chemical properties and bio-medical applications.

M. Tegoni, M. Remelli, D. Valensin, 2014, Current medicinal chemistry.

Structural analysis of copper(I) interaction with amyloid β peptide.

H. Kozłowski, D. Valensin, A. Hecel, 2019, Journal of inorganic biochemistry.

Metal ion mediated transition from random coil to β-sheet and aggregation of Bri2-23, a natural inhibitor of Aβ aggregation.

L. Hemmingsen, D. Valensin, Riccardo De Ricco, 2015, Metallomics : integrated biometal science.

The extracellular loop of IRT1 ZIP protein--the chosen one for zinc?

H. Kozłowski, D. Valensin, S. Potocki, 2013, Journal of inorganic biochemistry.

The zinc-binding fragment of HypA from Helicobacter pylori: a tempting site also for nickel ions.

H. Kozłowski, M. Rowińska-Żyrek, D. Valensin, 2013, Dalton transactions.

The unusual stabilization of the Ni2+ and Cu2+ complexes with NSFRY.

S. Ołdziej, H. Kozłowski, M. Remelli, 2013, Dalton transactions.

Coordination of Ni2+ and Cu2+ to metal ion binding domains of E. coli SlyD protein.

H. Kozłowski, M. Rowińska-Żyrek, W. Kamysz, 2012, Journal of inorganic biochemistry.

Metal binding ability of cysteine-rich peptide domain of ZIP13 Zn2+ ions transporter.

H. Kozłowski, M. Rowińska-Żyrek, D. Valensin, 2011, Inorganic chemistry.

The role of His-50 of α-synuclein in binding Cu(II): pH dependence, speciation, thermodynamics and structure.

M. C. Baratto, H. Kozłowski, M. Remelli, 2011, Metallomics : integrated biometal science.

The C terminus of HspA--a potential target for native Ni(II) and Bi(III) anti-ulcer drugs.

H. Kozłowski, M. Rowińska-Żyrek, W. Kamysz, 2010, Dalton transactions.

Copper binding to chicken and human prion protein amylodogenic regions: differences and similarities revealed by Ni2+ as a diamagnetic probe.

H. Kozłowski, W. Kamysz, Karolina Gajda, 2010, Journal of inorganic biochemistry.

Specific interactions of Bi(III) with the Cys-Xaa-Cys unit of a peptide sequence.

H. Kozłowski, M. Rowińska-Żyrek, Z. Grzonka, 2009, Dalton transactions.

Copper(II) coordination outside the tandem repeat region of an unstructured domain of chicken prion protein.

H. Kozłowski, W. Barańska-Rybak, D. Bacco, 2009, Molecular bioSystems.

Binding of Ni2+ and Cu2+ ions to peptides with a Cys-His motif.

H. Kozłowski, W. Kamysz, D. Valensin, 2008, Dalton transactions.

CuII binding sites located at His-96 and His-111 of the human prion protein: thermodynamic and spectroscopic studies on model peptides.

H. Kozłowski, W. Kamysz, R. Guerrini, 2008, Dalton transactions.

The His-His sequence of the antimicrobial peptide demegen P-113 makes it very attractive ligand for Cu2+.

H. Kozłowski, W. Kamysz, D. Valensin, 2008, Journal of inorganic biochemistry.

Structural and dynamic characterization of copper(II) binding of the human prion protein outside the octarepeat region.

R. Pogni, H. Kozłowski, R. Guerrini, 2007, Chemistry.

Is the monomeric prion octapeptide repeat PHGGGWGQ a specific ligand for Cu2+ ions?

H. Kozłowski, K. Rolka, D. Valensin, 2002 .

Co-ordination ability towards CuII of the 29-amino acid residue trypsin inhibitor of squash and two of its analogues

J. Otlewski, P. Młynarz, H. Kozłowski, 2001 .

Copper, iron, and zinc ions homeostasis and their role in neurodegenerative disorders (metal uptake, transport, distribution and regulation)

H. Kozłowski, D. Valensin, G. Valensin, 2009 .

Specificity in the Cu2+ interactions with prion protein fragments and related His-rich peptides from mammals to fishes

P. Stańczak, H. Kozłowski, D. Valensin, 2008 .

Copper(I) Forms a Redox-Stable 1:2 Complex with α-Synuclein N-Terminal Peptide in a Membrane-Like Environment.

E. Monzani, L. Casella, S. Dell'Acqua, 2016, Inorganic chemistry.

The effect of a membrane-mimicking environment on the interactions of Cu2+ with an amyloidogenic fragment of chicken prion protein.

H. Kozłowski, D. Valensin, A. Hecel, 2017, Dalton transactions.

Cu(II) ion coordination to the pentadecapeptide model of the SPARC copper-binding site

P. Młynarz, H. Kozłowski, W. Kamysz, 2002 .

NMR metabolomic investigation of astrocytes interacted with Aβ₄₂ or its complexes with either copper(II) or zinc(II).

Altea Rocchi, R. Barbucci, H. Kozłowski, 2012, Journal of inorganic biochemistry.

Structural characterization of Cu2+, Ni2+ and Zn2+ binding sites of model peptides associated with neurodegenerative diseases

D. Valensin, Caterina Migliorini, Marek Luczkowski, 2012 .

1H and 13C-NMR and molecular dynamics studies of cyclosporin a interacting with magnesium(II) or cerium(III) in acetonitrile. Conformational changes and cis-trans conversion of peptide bonds.

Elena Molteni, Francesca Bernardi, Daniela Valensin, 2006, Biophysical journal.

1H and 13C NMR study of the complex formed by copper(II) with the nucleoside antibiotic sinefungin.

M. Jeżowska‐Bojczuk, D. Valensin, G. Valensin, 2007, Journal of inorganic biochemistry.

Dynamic Interplay between Copper Toxicity and Mitochondrial Dysfunction in Alzheimer’s Disease

C. Pozzi, D. Valensin, G. Tassone, 2021, Life.

Metal compounds as inhibitors of β-amyloid aggregation. Perspectives for an innovative metallotherapeutics on Alzheimer's disease

L. Messori, D. Valensin, C. Gabbiani, 2012 .

Structural features of the Cu(II) complex with the rat Abeta(1-28) fragment.

H. Kozłowski, Z. Grzonka, D. Valensin, 2008, Chemical communications.

Influence of membrane environments and copper ions on the structural features of amyloidogenic proteins correlated to neurodegeneration

D. Valensin, A. Hecel, R. D. Ricco, 2016 .

Structure, Function, Involvement in Diseases and Targeting of 14-3-3 Proteins: An Update.

Maurizio Botta, Mattia Mori, Ylenia Cau, 2017, Current medicinal chemistry.

Specific binding modes of Cu(I) and Ag(I) with neurotoxic domain of the human prion protein.

H. Kozłowski, D. Valensin, A. Hecel, 2016, Journal of inorganic biochemistry.

Copper-induced structural propensities of the amyloidogenic region of human prion protein

H. Kozłowski, A. Sinicropi, D. Valensin, 2014, JBIC Journal of Biological Inorganic Chemistry.

Impact of SDS surfactant on the interactions of Cu(2+) ions with the amyloidogenic region of human prion protein.

H. Kozłowski, D. Valensin, A. Hecel, 2015, Dalton transactions.

The specificity of interaction of Zn(2+), Ni(2+) and Cu(2+) ions with the histidine-rich domain of the TjZNT1 ZIP family transporter.

H. Kozłowski, D. Valensin, S. Potocki, 2014, Dalton transactions.

Exploring the reactions of β-amyloid (Aβ) peptide 1-28 with Al(III) and Fe(III) ions.

L. Messori, H. Kozłowski, G. La Penna, 2011, Inorganic chemistry.

Chemically stable inhibitors of 14-3-3 protein–protein interactions derived from BV02

A. Angelucci, M. Botta, M. Mori, 2019, Journal of enzyme inhibition and medicinal chemistry.

Copper(I)-α-synuclein interaction: structural description of two independent and competing metal binding sites.

L. Bubacco, E. Monzani, L. Casella, 2013, Inorganic chemistry.

Coordination and redox properties of copper interaction with α-synuclein.

L. Casella, H. Kozłowski, S. Dell'Acqua, 2016, Journal of inorganic biochemistry.

NMR investigations of metal interactions with unstructured soluble protein domains

H. Kozłowski, D. Valensin, S. Potocki, 2014 .

Thermodynamic and spectroscopic investigation on the role of Met residues in Cu(II) binding to the non-octarepeat site of the human prion protein.

H. Kozłowski, R. Guerrini, M. Remelli, 2012, Metallomics : integrated biometal science.

Novel Perspective on Alzheimer’s Disease Treatment: Rosmarinic Acid Molecular Interplay with Copper(II) and Amyloid β

S. Lamponi, D. Valensin, A. Hecel, 2020, Life.

Metal Complexes of Two Specific Regions of ZnuA, a Periplasmic Zinc(II) Transporter from Escherichia coli

H. Kozłowski, M. Rowińska-Żyrek, D. Valensin, 2020, Inorganic chemistry.

Glutathione and phytochelatins jointly allow intracellular and extracellular detoxification of cadmium in the liverwort Marchantia polymorpha

C. Varotto, A. Saba, A. Andreucci, 2023, Environmental and Experimental Botany.

Copper Binding and Redox Activity of α-Synuclein in Membrane-Like Environment

L. Bubacco, S. Mangani, E. Monzani, 2023, Biomolecules.

Interaction of ferulic acid derivatives with human erythrocytes monitored by pulse field gradient NMR diffusion and NMR relaxation studies.

N. Gaggelli, D. Valensin, C. Anselmi, 2005, Chemistry and physics of lipids.

Heteronuclear and homonuclear Cu2+ and Zn2+ complexes with multihistidine peptides based on zebrafish prion-like protein.

E. Jankowska, A. Szymańska, H. Kozłowski, 2009, Inorganic chemistry.

A Comparative Study between Lycorine and Galantamine Abilities to Interact with AMYLOID β and Reduce In Vitro Neurotoxicity

S. Lamponi, D. Valensin, A. Kola, 2023, International journal of molecular sciences.

Structural features of the Zn(2+) complex with the single repeat region of "prion related protein" (PrP-rel-2) of zebrafish zPrP63-70 fragment.

H. Kozłowski, D. Valensin, G. Valensin, 2009, Dalton transactions.

A Deep Learning Approach to Analyze NMR Spectra of SH-SY5Y Cells for Alzheimer’s Disease Diagnosis

M. Bianchini, F. Scarselli, D. Valensin, 2023, Mathematics.

Metal complexation mechanisms of polyphenols associated to Alzheimer's Disease.

D. Valensin, D. Dudek, A. Kola, 2021, Current medicinal chemistry.

Synthesis, X-ray structure analysis and density functional study of an unusual anhydrous 5,6-dimethylbenzo-1,3-imidazolium(H3) chloride

G. Tamasi, R. Cini, D. Valensin, 2015 .

Contents of Volumes in the Metal Ions in Life Sciences Series

Jennifer C. Lee, T. Bayer, H. Gray, 2019, Metal Ions in Bio-Imaging Techniques.

Bioinorganic Chemistry of Micronutrients Related to Alzheimer’s and Parkinson’s Diseases

D. Valensin, A. Kola, Federico Nencioni, 2023, Molecules.

Fine tuning the structure of the Cu2+ complex with the prion protein chicken repeat by proline isomerization.

P. Stańczak, H. Kozłowski, Z. Grzonka, 2005, Chemical communications.

Semenogelins Armed in Zn(II) and Cu(II): May Bioinorganic Chemistry Help Nature to Cope with Enterococcus faecalis?

M. Rowińska-Żyrek, D. Valensin, D. Dudek, 2023, Inorganic chemistry.

fac-{Ru(CO)(3)}(2+) selectively targets the histidine residues of the beta-amyloid peptide 1-28. Implications for new Alzheimer's disease treatments based on ruthenium complexes.

L. Messori, H. Kozłowski, G. Tamasi, 2010, Inorganic chemistry.

Bioinorganic chemistry of Parkinson's disease: structural determinants for the copper-mediated amyloid formation of alpha-synuclein.

P. Carloni, C. Griesinger, A. Magistrato, 2010, Inorganic chemistry.

Exploring the reactions of β-amyloid (Aβ) peptide 1-28 with Al(III) and Fe(III) ions.

L. Messori, H. Kozłowski, G. La Penna, 2011, Inorganic chemistry.

A Combined NMR and UV–Vis Approach to Evaluate Radical Scavenging Activity of Rosmarinic Acid and Other Polyphenols

M. C. Baratto, D. Valensin, A. Kola, 2023, Molecules.

Histidine-Rich C-Terminal Tail of Mycobacterial GroEL1 and Its Copper Complex—The Impact of Point Mutations

M. Capdevila, Ò. Palacios, D. Valensin, 2023, Inorganic chemistry.

Copper Forms a PPII Helix-Like Structure with the Catalytic Domains of Bacterial Zinc Metalloproteases

D. Valensin, S. Potocki, A. Kola, 2023, Inorganic chemistry.

The role of His-50 of α-synuclein in binding Cu(II): pH dependence, speciation, thermodynamics and structure.

M. C. Baratto, H. Kozłowski, M. Remelli, 2011, Metallomics : integrated biometal science.

Copper Homeostasis and Neurodegenerative Disorders (Alzheimer′s, Prion, and Parkinson′s Diseases and Amyotrophic Lateral Sclerosis)

H. Kozłowski, D. Valensin, G. Valensin, 2006 .

Copper(I)-α-synuclein interaction: structural description of two independent and competing metal binding sites.

L. Bubacco, E. Monzani, L. Casella, 2013, Inorganic chemistry.

Reactivity of copper-α-synuclein peptide complexes relevant to Parkinson's disease.

E. Monzani, L. Casella, Stefania Nicolis, 2015, Metallomics : integrated biometal science.

Differences in the binding of copper(I) to α- and β-synuclein.

L. Bubacco, S. Mangani, L. Casella, 2015, Inorganic chemistry.

Conformation propensities of des-acyl-ghrelin as probed by CD and NMR

D. Valensin, G. Valensin, E. Gaggelli, 2013, Peptides.

Exploration of Lycorine and Copper(II)’s Association with the N-Terminal Domain of Amyloid β

D. Valensin, A. Kola, Ginevra Vigni, 2023, Inorganics.

NMR-Based Structural Insights on Folic Acid and Its Interactions with Copper(II) Ions

D. Valensin, A. Kola, 2024, Inorganics.

Zn(II)-alloferon complexes - Similar sequence, different coordination modes, no antibacterial activity.

M. Rowińska-Żyrek, D. Valensin, D. Dudek, 2020, Journal of inorganic biochemistry.