A. Katsumi

发表

Type 1 von Willebrand disease mutation Cys1149Arg causes intracellular retention and degradation of heterodimers: a possible general mechanism for dominant mutations of oligomeric proteins.

J. Eikenboom, J. Sadler, E. Tuley, 2001, Blood.

Anemia in older adults as a geriatric syndrome: A review

T. Matsushita, S. Tamura, A. Katsumi, 2021, Geriatrics & gerontology international.

Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis

H. Saito, T. Naoe, Koji Yamamoto, 2008, International journal of hematology.

L1503R is a member of group I mutation and has dominant‐negative effect on secretion of full‐length VWF multimers: an analysis of two patients with type 2A von Willebrand disease

T. Naoe, T. Murate, J. Takamatsu, 2008, Haemophilia : the official journal of the World Federation of Hemophilia.

Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy

T. Naoe, Jean Y. J. Wang, C. Jamieson, 2008, International journal of hematology.

Mutational analysis of SOS1 gene in acute myeloid leukemia

T. Naoe, Y. Ishikawa, K. Kaibuchi, 2008, International journal of hematology.

Periosteum-derived podoplanin-expressing stromal cells regulate nascent vascularization during epiphyseal marrow development

W. Fujii, F. Hayakawa, T. Matsushita, 2022, The Journal of biological chemistry.

Periosteum-derived podoplanin-expressing stromal cells regulate nascent vascularization during epiphyseal marrow development

F. Hayakawa, T. Matsushita, A. Takagi, 2021, bioRxiv.

Protein C Nagoya, an elongated mutant of protein C, is retained within the endoplasmic reticulum and is associated with GRP78 and GRP94.

T. Senda, M. Hamaguchi, H. Saito, 1996, Blood.

Donor single nucleotide polymorphism in the CCR9 gene affects the incidence of skin GVHD

Y. Kodera, T. Naoe, R. Suzuki, 2010, Bone Marrow Transplantation.

RHOF PROMOTES MURINE MARGINAL ZONE B CELL DEVELOPMENT

T. Naoe, M. Ikawa, H. Kiyoi, 2014, Nagoya journal of medical science.

Recurrent Intramural Hematoma of the Small Intestine in a Severe Hemophilia A Patient with a High Titer of Factor VIII Inhibitor: A Case Report and Review of the Literature

T. Naoe, Koji Yamamoto, J. Takamatsu, 2006, International journal of hematology.

Fatal thrombosis of antithrombin‐deficient mice is rescued differently in the heart and liver by intercrossing with low tissue factor mice

H. Saito, T. Naoe, M. Hayashi, 2006, Journal of thrombosis and haemostasis : JTH.

Myh9 R702C is associated with erythroid abnormality with splenomegaly in mice

Y. Ishikawa, H. Saito, H. Kiyoi, 2021, Nagoya journal of medical science.

dominant mutations of oligomeric proteins retention and degradation of heterodimers: a possible general mechanism for Type 1 von Willebrand disease mutation Cys1149Arg causes intracellular

J. Eikenboom, J. Sadler, E. Tuley, 2013 .

Protein S-Leu17Pro disrupts the hydrophobicity of its signal peptide causing a proteasome-dependent degradation.

F. Hayakawa, W. Fujii, T. Matsushita, 2021, Thrombosis research.

Apparent synonymous mutation F9 c.87A>G causes secretion failure by in-frame mutation with aberrant splicing.

F. Hayakawa, T. Matsushita, A. Takagi, 2019, Thrombosis research.

Structural organization and promoter activity of the human ryudocan gene.

S. Tsuzuki, A. Takagi, M. Hamaguchi, 1996, Journal of biochemistry.

Molecular basis of a hereditary type I protein S deficiency caused by a substitution of Cys for Arg474.

J. Takamatsu, M. Hamaguchi, I. Sugiura, 1996, Blood.

A novel RUNX1-C11orf41 fusion gene in a case of acute myeloid leukemia with a t(11;21)(p14;q22).

T. Naoe, N. Emi, A. Katsumi, 2012, Cancer Genetics.

Aberrant X chromosomal rearrangement through multi‐step template switching during sister chromatid formation in a patient with severe hemophilia A

F. Hayakawa, T. Matsushita, A. Takagi, 2020, Molecular genetics & genomic medicine.

BCR‐ABL‐independent and RAS / MAPK pathway‐dependent form of imatinib resistance in Ph‐positive acute lymphoblastic leukemia cell line with activation of EphB4

T. Naoe, N. Emi, H. Kiyoi, 2010, European journal of haematology.

Definite diagnosis in Japanese patients with protein C deficiency by identification of causative PROC mutations

T. Naoe, T. Murate, Koji Yamamoto, 2009, International journal of hematology.

Molecular cloning, genomic organization, promoter activity, and tissue-specific expression of the mouse ryudocan gene.

S. Tsuzuki, I. Sugiura, H. Saito, 1997, Journal of biochemistry.

Human Ryudocan from Endothelium-like Cells Binds Basic Fibroblast Growth Factor, Midkine, and Tissue Factor Pathway Inhibitor (*)

T. Muramatsu, T. Nagasaka, A. Katsumi, 1996, The Journal of Biological Chemistry.

Establishment of a Stroma-Dependent Human Acute Myelomonocytic Leukemia Cell Line, NAMO-2, with FLT3 Tandem Duplication

T. Naoe, N. Emi, H. Kiyoi, 2006, International journal of hematology.

Humoral and cellular immunity to an encoded protein induced by direct DNA injection.

N. Emi, H. Saito, A. Abe, 1994, Human gene therapy.

VWF‐Gly2752Ser, a novel non‐cysteine substitution variant in the CK domain, exhibits severe secretory impairment by hampering C‐terminal dimer formation

H. Kiyoi, F. Hayakawa, T. Matsushita, 2022, Journal of thrombosis and haemostasis : JTH.

Prognostic analysis of aberrant somatic hypermutation of RhoH gene in diffuse large B cell lymphoma

T. Naoe, T. Kinoshita, H. Kiyoi, 2007, Leukemia.

Prognostic Analysis of Aberrant Somatic Hypermutation of RhoH in Diffuse Large B Cell Lymphoma.

T. Naoe, T. Kinoshita, H. Kiyoi, 2006 .

Targeted disruption of mouse ortholog of the human MYH9 responsible for macrothrombocytopenia with different organ involvement: hematological, nephrological, and otological studies of heterozygous KO mice.

T. Naoe, Masahide Takahashi, M. Hayashi, 2004, Biochemical and biophysical research communications.

High Titer of ADAMTS13 Inhibitor Associated with Thrombotic Microangiopathy of the Gut and Skeletal Muscle after Allogeneic Hematopoietic Stem Cell Transplantation

T. Naoe, M. Hayashi, H. Saito, 2006, International journal of hematology.

In vitro exploration of latent prothrombin mutants conveying antithrombin resistance.

A. Takagi, T. Kojima, S. Tamura, 2017, Thrombosis research.

Skewed X chromosome inactivation in fraternal female twins results in moderately severe and mild haemophilia B

T. Naoe, T. Murate, T. Matsushita, 2008, Haemophilia : the official journal of the World Federation of Hemophilia.

Impact of variation in reagent combinations for one‐stage clotting assay on assay discrepancy in nonsevere haemophilia A

H. Kiyoi, T. Matsushita, T. Kojima, 2020, International journal of laboratory hematology.

Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation

T. Naoe, T. Murate, Koji Yamamoto, 2010, International journal of hematology.

A CASE OF DELAYED ERYTHROPOIESIS AFTER BONE MARROW TRANSPLANTATION FROM AN ABO-COMPATIBLE SIBLING DONOR FOR ACQUIRED CHRONIC PURE RED CELL APLASIA

T. Naoe, H. Kiyoi, A. Katsumi, 2017 .

Localization of Disulfide Bonds in the Cystine Knot Domain of Human von Willebrand Factor*

J. Sadler, E. Tuley, I. Bodó, 2000, The Journal of Biological Chemistry.

Severe Factor VII Deficiency Caused by a Novel Mutation His348 to Gln in the Catalytic Domain

H. Saito, T. Matsushita, I. Sugiura, 2000, Thrombosis and Haemostasis.

Essential role of a carboxyl‐terminal α‐helix motif in the secretion of coagulation factor XI

F. Hayakawa, T. Matsushita, A. Takagi, 2021, Journal of thrombosis and haemostasis : JTH.

Prognostic implication and biological roles of RhoH in acute myeloid leukaemia

T. Naoe, Y. Ishikawa, K. Kaibuchi, 2008, European journal of haematology.

Y654 of β‐catenin is essential for FLT3/ITD‐related tyrosine phosphorylation and nuclear localization of β‐catenin

T. Naoe, H. Kiyoi, A. Katsumi, 2012, European journal of haematology.

Development and validation of a novel qualitative test for plasma fibrinogen utilizing clot waveform analysis

T. Matsushita, S. Tamura, A. Katsumi, 2022, Scientific Reports.

Genetic analysis of protein C deficiency in nineteen Japanese families: five recurrent defects can explain half of the deficiencies.

T. Miyata, A. Shirahata, H. Kato, 1998, Thrombosis research.

Two Distinct Novel Splice Site Mutations in a Compound Heterozygous Patient with Protein S Deficiency

H. Saito, S. Tsuzuki, I. Sugiura, 1997, Thrombosis and Haemostasis.

A Novel Nonsense Mutation Associated with an Exon Skipping in a Patient with Hereditary Protein S Deficiency Type I

H. Saito, J. Takamatsu, Y. Okamoto, 1996, Thrombosis and Haemostasis.

The carboxyl-terminal region of protein C is essential for its secretion.

T. Senda, H. Umeyama, I. Sugiura, 2000, Blood.

A Quantitative Protein S Deficiency Associated with a Novel Nonsense Mutation and Markedly Reduced Levels of Mutated mRNA

H. Saito, J. Takamatsu, M. Hamaguchi, 1995, Thrombosis and Haemostasis.

Virus-associated hemophagocytic syndrome caused by pandemic swine-origin influenza A (H1N1) in a patient after unrelated bone marrow transplantation.

T. Naoe, H. Kiyoi, T. Matsushita, 2011, Journal of clinical and experimental hematopathology : JCEH.

F9 mRNA splicing aberration due to a deep Intronic structural variation in a patient with moderate hemophilia B.

F. Hayakawa, T. Matsushita, K. Nogami, 2022, Thrombosis research.

Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice

T. Naoe, T. Suda, T. Kinoshita, 2007, Leukemia.

Identification of amino acid residues essential for heparin binding by the A1 domain of human von Willebrand factor.

T. Naoe, H. Saito, T. Matsushita, 2006, Biochemical and biophysical research communications.

Mutation of ARHGAP9 in patients with coronary spastic angina

T. Naoe, T. Takenawa, K. Kaibuchi, 2010, Journal of Human Genetics.

Protein S (PS) is a vitamin K-dependent plasma glycoprotein that acts as a cofactor for activated protein C (APC) in the inactivation of the procoagulant factors Va and Villa (1). PS also directly inhibits fac

H. Saito, J. Takamatsu, Y. Okamoto, 2018 .

FLT3/ ITD regulates leukaemia cell adhesion through α4β1 integrin and Pyk2 signalling

T. Naoe, K. Kaibuchi, T. Senga, 2011, European journal of haematology.

Rho‐kinase and myosin II activities are required for cell type and environment specific migration

K. Kaibuchi, M. Amano, M. Takefuji, 2005, Genes to cells : devoted to molecular & cellular mechanisms.

Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1–RUNX1T1 leukemia with t(8;12;21)

T. Kameyama, A. Mayeda, N. Emi, 2018, International Journal of Hematology.

LRP16 is fused to RUNX1 in monocytic leukemia cell line with t(11;21)(q13;q22)

T. Naoe, N. Emi, H. Kiyoi, 2007, European journal of haematology.

Truncated RUNX1 Generated by the Fusion of RUNX1 to Antisense GRIK2 via a Cryptic Chromosome Translocation Enhances Sensitivity to Granulocyte Colony-Stimulating Factor

Hideyuki Yamamoto, N. Emi, A. Tomita, 2020, Cytogenetic and Genome Research.

Molecular basis of SERPINC1 mutations in Japanese patients with antithrombin deficiency.

F. Hayakawa, T. Matsushita, A. Takagi, 2019, Thrombosis research.

Carrier Detection and Prenatal Diagnosis of Hemophilia B Using DNA Polymorphisms of the Factor IX Gene in Japanese Subjects

J. Takamatsu, H. Saito, T. Matsushita, 1996 .

Analysis for antithrombin gene polymorphisms in Japanese subjects and cosegregation studies in families with hereditary antithrombin deficiency.

S. Tsuzuki, J. Takamatsu, I. Sugiura, 1996, Thrombosis Research.

Impaired secretion of carboxyl-terminal truncated factor VII due to an F7 nonsense mutation associated with FVII deficiency.

T. Naoe, T. Murate, T. Matsushita, 2010, Thrombosis research.

The Carboxyl-Terminal Region of Protein C Is Essential for Its Secretion

H. Saito, T. Senda, H. Umeyama, 1998 .

Molecular Pathogenesis of Protein C-Nagoya, a Hereditary Type I Protein C Deficiency

H. Saito, T. Kojima, I. Sugiura, 1996 .

Acute lymphoblastic leukaemia in a child with hereditary elliptocytosis

H. Russcher, C. Rehder, A. Dorgalaleh, 2022 .