J. Van den Eynden

发表

Somatic Mutation Patterns in Hemizygous Genomic Regions Unveil Purifying Selection during Tumor Evolution

E. Larsson, S. Basu, J. Van den Eynden, 2016, PLoS genetics.

Lack of detectable neoantigen depletion signals in the untreated cancer genome

Martin L. Miller, E. Larsson, A. Jiménez-Sánchez, 2019, Nature Genetics.

Glycine enhances microglial intracellular calcium signaling. A role for sodium-coupled neutral amino acid transporters

J. Rigo, N. Hellings, P. Steels, 2011, Pflügers Archiv - European Journal of Physiology.

11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma.

H. Carén, K. Beiske, R. Palmer, 2020, Cell reports.

Benchmark of tools for in silico prediction of MHC class I and class II genotypes from NGS data

K. Marchal, J. Van den Eynden, A. Claeys, 2022, bioRxiv.

An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34a

E. Larsson, P. Johnsson, J. Serviss, 2017, Cell Death & Disease.

A clinically annotated post-mortem approach to study multi-organ somatic mutational clonality in normal tissues

A. Vral, E. Larsson, T. Lammens, 2022, Scientific Reports.

Benchmark of tools for in silico prediction of MHC class I and class II genotypes from NGS data

K. Marchal, J. Van den Eynden, A. Claeys, 2022, bioRxiv.

The inhibitory neurotransmitter glycine modulates macrophage activity by activation of neutral amino acid transporters

J. Rigo, N. Hellings, P. Stinissen, 2010, Journal of neuroscience research.

Dorsal unpaired median neurons of locusta migratoria express ivermectin- and fipronil-sensitive glutamate-gated chloride channels.

J. Rigo, C. Derst, J. Van den Eynden, 2007, Journal of neurophysiology.

Novel human-derived EML4-ALK fusion cell lines identify ribonucleotide reductase RRM2 as a target of activated ALK in NSCLC.

R. Doebele, A. Le, R. Palmer, 2022, Lung cancer.

Low immunogenicity of common cancer hot spot mutations resulting in false immunogenic selection signals

K. Marchal, J. Van den Eynden, A. Claeys, 2021, PLoS genetics.

Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events

Erik Larsson, Jimmy Van den Eynden, E. Larsson, 2016, Nature Communications.

Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib

E. Larsson, R. Palmer, B. Hallberg, 2018, Cold Spring Harbor molecular case studies.

Network-Based Analysis to Identify Drivers of Metastatic Prostate Cancer Using GoNetic

K. Marchal, M. Larmuseau, J. Van den Eynden, 2021, Cancers.

ATR inhibition enables complete tumour regression in ALK-driven NB mouse models

R. Palmer, B. Hallberg, G. Umapathy, 2021, Nature Communications.

Loss of RET Promotes Mesenchymal Identity in Neuroblastoma Cells

R. Palmer, B. Hallberg, Wancun Zhang, 2021, Cancers.

Phosphoproteome and gene expression profiling of ALK inhibition in neuroblastoma cell lines reveals conserved oncogenic pathways

E. Larsson, J. Koster, R. Palmer, 2018, Science Signaling.

ALK ligand ALKAL2 potentiates MYCN‐driven neuroblastoma in the absence of ALK mutation

T. Masudi, J. Koster, R. Palmer, 2021, The EMBO journal.

A clinically annotated post-mortem approach to study multi-organ somatic mutational clonality in histologically healthy tissues

A. Vral, E. Larsson, T. Lammens, 2022, bioRxiv.

Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers

E. Larsson, A. Ståhlberg, S. Filges, 2018, bioRxiv.

Recurrent promoter mutations in melanoma are defined by an extended context-specific mutational signature

Erik Larsson, Anders Ståhlberg, Jimmy Van den Eynden, 2017, bioRxiv.

Targeting Filamin A Reduces Macrophage Activity and Atherosclerosis.

G. Bergström, J. Borén, E. Larsson, 2019, Circulation.

Quantification of Neoantigen-Mediated Immunoediting in Cancer Evolution-Letter.

J. Van den Eynden, A. Claeys, 2023, Cancer research.

Mutational Signatures Are Critical for Proper Estimation of Purifying Selection Pressures in Cancer Somatic Mutation Data When Using the dN/dS Metric

E. Larsson, J. Van den Eynden, 2017, Front. Genet..

Pathway Relevance Ranking for Tumor Samples through Network-Based Data Integration

Kathleen Marchal, Piet Demeester, Jan Fostier, 2015, PloS one.

ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression

R. Doebele, A. Le, R. Palmer, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Pharmacologic RNA splicing modulation: a novel mechanism to enhance neoantigen-directed anti-tumor immunity and immunotherapy response

J. Nilsson, K. Elliott, J. Van den Eynden, 2021, Signal Transduction and Targeted Therapy.

A highly reliable and budget‐friendly Peltier‐cooled camera for biological fluorescence imaging microscopy

M. Ameloot, M. Vandeven, J. Van den Eynden, 2007, Journal of microscopy.

Lack of detectable neoantigen depletion signals in the untreated cancer genome

Martin L. Miller, A. Jiménez-Sánchez, J. Van den Eynden, 2019, Nature Genetics.

An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34a

E. Larsson, P. Johnsson, J. Serviss, 2017, bioRxiv.

The genetic structure of the Belgian population

E. Goetghebeur, J. Vermeesch, S. Demarest, 2018, Human Genomics.

11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma.

H. Carén, K. Beiske, R. Palmer, 2020, Cell reports.

Targeting Filamin A Reduces Macrophage Activity and Atherosclerosis.

G. Bergström, J. Borén, E. Larsson, 2019, Circulation.

Benchmark of tools for in silico prediction of MHC class I and class II genotypes from NGS data

K. Marchal, J. Van den Eynden, A. Claeys, 2023, BMC Genomics.