W. Zeng

发表

Regulation of Cl−/ HCO3 −Exchange by Cystic Fibrosis Transmembrane Conductance Regulator Expressed in NIH 3T3 and HEK 293 Cells*

M. G. Lee, Min Goo Lee, S. Muallem, 1999, The Journal of Biological Chemistry.

Structures of the Calcium-activated Non-Selective Cation Channel TRPM4

X. Bai, J. She, Youxing Jiang, 2017, Nature.

Structural mechanisms of phospholipid activation of the human TPC 2 1 channel 2

X. Bai, J. She, Youxing Jiang, 2022 .

Spinophilin/neurabin reciprocally regulate signaling intensity by G protein‐coupled receptors

P. Greengard, P. Allen, S. Muallem, 2007, The EMBO journal.

Spinophilin regulates Ca 2 + signalling by binding the N-terminal domain of RGS 2 and the third intracellular loop of G-protein-coupled receptors

P. Greengard, P. Allen, S. Muallem, 2005 .

Sodium and potassium competition in potassium-selective and non-selective channels

D. Sauer, Youxing Jiang, Y. Lam, 2013, Nature Communications.

Slc26a6 regulates CFTR activity in vivo to determine pancreatic duct HCO3− secretion: relevance to cystic fibrosis

S. Muallem, P. Thomas, C. Marino, 2006, The EMBO journal.

Serine-threonine kinase with-no-lysine 4 (WNK4) controls blood pressure via transient receptor potential canonical 3 (TRPC3) in the vasculature

Min Goo Lee, S. Muallem, J. Y. Kim, 2011, Proceedings of the National Academy of Sciences.

Structural and functional characterization of an otopetrin family 1 proton channel 2

X. Bai, J. She, W. Zeng, 2019 .

A New Mode of Ca2+ Signaling by G Protein-Coupled Receptors Gating of IP3 Receptor Ca2+ Release Channels by Gβγ

Don-On Daniel Mak, Weizhong Zeng, Qin Li, 2003, Current Biology.

Gβγ Transduces [Ca2+]i Oscillations and Gαq a Sustained Response during Stimulation of Pancreatic Acinar Cells with [Ca2+]i-mobilizing Agonists*

S. Muallem, W. Zeng, Xin Xu, 1996, The Journal of Biological Chemistry.

Membrane-specific Regulation of Cl− Channels by Purinergic Receptors in Rat Submandibular Gland Acinar and Duct Cells*

M. G. Lee, Min Goo Lee, S. Muallem, 1997, The Journal of Biological Chemistry.

Characterization and Localization of P2 Receptors in Rat Submandibular Gland Acinar and Duct Cells*

M. G. Lee, S. Muallem, W. Zeng, 1997, The Journal of Biological Chemistry.

The Mammalian Sec6/8 Complex Interacts with Ca2+ Signaling Complexes and Regulates Their Activity

S. Muallem, D. Shin, M. Mozhayeva, 2000, The Journal of cell biology.

Signaling Complexes and Regulates their Activity

S. Muallem, D. Shin, M. Mozhayeva, 2000 .

Regulation of the Inositol 1,4,5-Trisphosphate-activated Ca Channel by Activation of G Proteins (*)

S. Muallem, W. Zeng, Xin Xu, 1996, The Journal of Biological Chemistry.

Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors

P. Greengard, P. Allen, S. Muallem, 2005, Nature Cell Biology.

IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct.

K. Mikoshiba, I. So, S. Muallem, 2008, The Journal of clinical investigation.

Structural Insight into the Ion-Exchange Mechanism of the Sodium/Calcium Exchanger

Weizhong Zeng, David B. Sauer, Youxing Jiang, 2012, Science.

Peptidyl-Prolyl Isomerase FKBP52 Controls Chemotropic Guidance of Neuronal Growth Cones via Regulation of TRPC1 Channel Opening

Joseph P. Yuan, P. Worley, G. Ming, 2009, Neuron.

SOAR and the polybasic STIM1 domains gate and regulate the Orai channels

Joseph P. Yuan, P. Worley, S. Muallem, 2009, Nature Cell Biology.

Polarized Expression of Ca2+ Channels in Pancreatic and Salivary Gland Cells

Min Goo Lee, S. Muallem, R. Wojcikiewicz, 1997, The Journal of Biological Chemistry.

Spacial Compartmentalization of Ca2+ Signaling Complexes in Pancreatic Acini*

S. Muallem, W. Zeng, Xin Xu, 1996, The Journal of Biological Chemistry.

RGS Proteins Determine Signaling Specificity of Gq-coupled Receptors*

S. Muallem, S. Offermanns, I. Davignon, 1999, The Journal of Biological Chemistry.

TRPC channels as STIM1-regulated store-operated channels.

Min Goo Lee, Joseph P. Yuan, P. Worley, 2007, Cell calcium.

STIM1 carboxyl-terminus activates native SOC, Icrac and TRPC1 channels

Joseph P. Yuan, P. Worley, S. Muallem, 2006, Nature Cell Biology.

Gating of CFTR by the STAS domain of SLC26 transporters

S. Muallem, H. Goto, L. Millen, 2004, Nature Cell Biology.

Polarized Expression of Ca2+ Pumps in Pancreatic and Salivary Gland Cells

S. Muallem, F. Wuytack, W. Zeng, 1997, The Journal of Biological Chemistry.

Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter

X. Bai, J. She, Youxing Jiang, 2019, Cell.

STIM1 gates TRPC channels, but not Orai1, by electrostatic interaction.

Joseph P. Yuan, Min Seuk Kim, P. Worley, 2008, Molecular cell.

STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels

Joseph P. Yuan, P. Worley, S. Muallem, 2007, Nature Cell Biology.

Ectopic expression of a rice plasma membrane intrinsic protein (OsPIP1;3) promotes plant growth and water uptake.

G. Calamita, Xiaodong Ding, Aoxue Wang, 2019, The Plant journal : for cell and molecular biology.

Cell-specific Behavior of P2X7 Receptors in Mouse Parotid Acinar and Duct Cells*

S. Muallem, Xiang Luo, Qin Li, 2003, Journal of Biological Chemistry.

Structural mechanism of allosteric activation of TRPML1 by PI(3,5)P2 and rapamycin

Youxing Jiang, W. Zeng, Yan Han, 2022, Proceedings of the National Academy of Sciences.

Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel

Youxing Jiang, W. Zeng, Yan Han, 2021, Neuron.

TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase

N. Grishin, J. Pei, Junmei Wang, 2021, eLife.

TMEM120 is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase

N. Grishin, J. Pei, Junmei Wang, 2021, bioRxiv.

Structural mechanisms of gating and selectivity of human rod CNGA1 channel

Youxing Jiang, W. Zeng, Yan Han, 2021, Neuron.

Figures and figure supplements Structural and functional characterization of an otopetrin family proton channel

X. Bai, J. She, Youxing Jiang, 2019 .

Structural mechanisms of phospholipid activation of the human TPC2 channel

Weizhong Zeng, Youxing Jiang, X. Bai, 2019, eLife.

Structural mechanisms of phospholipid activation of the human TPC2 channel

Weizhong Zeng, Youxing Jiang, X. Bai, 2019, eLife.

Structural insights into the voltage and phospholipid activation of mammalian TPC1 channel

X. Bai, J. She, Youxing Jiang, 2018, Nature.

Structure of Voltage-gated Two-pore Channel TPC1 from Arabidopsis thaliana

Youxing Jiang, Liping Chen, Yi Yang, 2015, Nature.

Ca2+-regulated Ca2+ channels with an RCK gating ring control plant symbiotic associations

Sunghoon Kim, Jean-Michel Ané, Muthusubramanian Venkateshwaran, 2019, Nature Communications.

Structural studies of ion permeation and Ca2+ blockage of a bacterial channel mimicking the cyclic nucleotide-gated channel pore

Youxing Jiang, A. Alam, W. Zeng, 2010, Proceedings of the National Academy of Sciences.

nNOS and Ca2+ influx in rat pancreatic acinar and submandibular salivary gland cells.

S. Muallem, S. Pandol, X. Xu, 1997, Cell calcium.

Distinct gating mechanisms revealed by the structures of a multi-ligand gated K+ channel

D. Sauer, Youxing Jiang, Liping Chen, 2012, eLife.

Crucial points within the pore as determinants of K⁺ channel conductance and gating.

Youxing Jiang, N. Shi, S. Ye, 2011, Journal of molecular biology.

TRPC channels as STIM1-regulated SOCs

Joseph P. Yuan, Min Seuk Kim, P. Worley, 2009, Channels.

Alternate Coupling of Receptors to Gs and Gi in Pancreatic and Submandibular Gland Cells*

S. Muallem, S. Mumby, I. Davignon, 1999, The Journal of Biological Chemistry.

Structure of mammalian endolysosomal TRPML1 channel in nanodiscs

X. Bai, J. She, Youxing Jiang, 2017, Nature.

Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1*

Joseph P. Yuan, Min Seuk Kim, P. Worley, 2009, Journal of Biological Chemistry.

Cryo-EM structure of the mitochondrial calcium uniporter

V. Mootha, Yifan Cheng, J. Armache, 2018, Nature.

Molecular determinants of fast Ca2+-dependent inactivation and gating of the Orai channels

P. Worley, I. So, S. Muallem, 2009, Proceedings of the National Academy of Sciences.

Ca2+ Signaling in Microdomains

P. Worley, S. Muallem, M. Dehoff, 2007, Journal of Biological Chemistry.

Homer proteins in Ca2+ signaling by excitable and non-excitable cells.

Joseph P. Yuan, Min Seuk Kim, P. Worley, 2007, Cell calcium.

ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice

S. Muallem, J. Stull, D. Ron, 2006, Journal of Cell Science.

Protein-protein interaction and functionTRPC channels

S. Muallem, J. Y. Kim, W. Zeng, 2005, Pflügers Archiv.

Tuning the ion selectivity of two-pore channels

Youxing Jiang, W. Zeng, Jiangtao Guo, 2017, Proceedings of the National Academy of Sciences.

Voltage-gating and cytosolic Ca2+ activation mechanisms of Arabidopsis two-pore channel AtTPC1

Youxing Jiang, Wei Yang, W. Zeng, 2021, Proceedings of the National Academy of Sciences.

Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations

X. Bai, Youxing Jiang, W. Zeng, 2020, eLife.

The Lysosomal Potassium Channel TMEM175 Adopts a Novel Tetrameric Architecture

Sunghoon Kim, J. She, Youxing Jiang, 2017, Nature.

Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites

D. Sauer, Youxing Jiang, N. Shi, 2010, Proceedings of the National Academy of Sciences.

Protein interactions central to stabilizing the K+ channel selectivity filter in a four-sited configuration for selective K+ permeation

D. Sauer, Youxing Jiang, W. Zeng, 2011, Proceedings of the National Academy of Sciences.

Structural implications of weak Ca2+ block in Drosophila cyclic nucleotide–gated channels

Youxing Jiang, Y. Lam, W. Zeng, 2015, The Journal of general physiology.

Regulatory interaction between CFTR and the SLC26 transporters.

S. Muallem, P. Thomas, S. Ko, 2006, Novartis Foundation symposium.

Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel.

J. Liou, Youxing Jiang, Wan-Ru Lee, 2023, Molecular cell.

The conserved potassium channel filter can have distinct ion binding profiles: Structural analysis of rubidium, cesium, and barium binding in NaK2K

D. Sauer, Youxing Jiang, Y. Lam, 2014, The Journal of general physiology.

Ionic interactions of Ba2+ blockades in the MthK K+ channel

Liping Chen, S. Ye, H. Cui, 2014, The Journal of general physiology.

Cryo-EM structure of human TPC2 channel in the ligand-bound closed state

X. Bai, J. She, Youxing Jiang, 2019 .

Analyses of RGS protein control of agonist-evoked Ca2+ signaling.

S. Muallem, Xiang Luo, W. Zeng, 2004, Methods in enzymology.

Native Store-operated Ca2+ Influx Requires the Channel Function of Orai1 and TRPC1*

Joseph P. Yuan, Min Seuk Kim, P. Worley, 2009, Journal of Biological Chemistry.

Structural mechanisms of the human cardiac sodium-calcium exchanger NCX1

M. Ottolia, Youxing Jiang, W. Zeng, 2023, Nature communications.

Cryo-EM structure of the mitochondrial calcium uniporter

V. Mootha, Yifan Cheng, J. Armache, 2018, Nature.

TRPML1 gating modulation by allosteric mutations and lipids

Youxing Jiang, W. Zeng, Yan Han, 2024, bioRxiv.