Kuo-Sen Huang

发表

Protein-protein interactions involved in the recognition of p27 by E3 ubiquitin ligase.

S. Reed, L. Vassilev, F. Podlaski, 2003, The Biochemical journal.

High-throughput screening for inhibitors of the Cks1-Skp2 interaction.

L. Vassilev, Kuo-Sen Huang, 2005, Methods in enzymology.

Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators.

Qing Xiang, Xiaolei Zhang, Y. Qian, 2013, Bioorganic & medicinal chemistry letters.

N-substituted sultam carboxylic acids as novel glycogen synthase activators

Qing Xiang, Xiaolei Zhang, Y. Qian, 2013 .

Protein – protein interactions involved in the recognition of p 27 by E 3 ubiquitin ligase

S. Reed, L. Vassilev, F. Podlaski, 2003 .

A selective phosphatase of regenerating liver phosphatase inhibitor suppresses tumor cell anchorage-independent growth by a novel mechanism involving p130Cas cleavage.

N. Fotouhi, D. Heimbrook, J. Reidhaar-Olson, 2008, Cancer research.

Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetes.

C. Rondinone, Yingsi Chen, Y. Qian, 2011, Journal of medicinal chemistry.

Modulation of E-selectin Structure/Function by Metal Ions

M. Anostario, Kuo-Sen Huang, 1995, The Journal of Biological Chemistry.

A Homogeneous Fluorescence Polarization Assay Adaptable for a Range of Protein Serine/Threonine and Tyrosine Kinases

J. Sportsman, Wei Huang, Yan Zhang, 2003, Journal of biomolecular screening.

Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization

Charles A. Wartchow, N. Fotouhi, Seng-Lai Tan, 2020, Science Advances.

High-throughput methods for measuring heparanase activity and screening potential antimetastatic and anti-inflammatory agents.

J. Roberts, L. Reik, W. Levin, 2004, Analytical biochemistry.

Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dyslipidemia.

S. So, I. Klein, Y. Qian, 2014, Journal of medicinal chemistry.

Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains

Kuo-Sen Huang, B. Graves, P. Familletti, 1994, Nature.

Two human 35 kd inhibitors of phospholipase A2 are related to substrates of pp60v-src and of the epidermal growth factor receptor/kinase

J. Browning, R. Mattaliano, R. Tizard, 1986, Cell.

[10] Delipidation, renaturation, and reconstitution of bacteriorhodopsin

H. Khorana, H. Bayley, E. London, 1982 .

Biosensor-based small molecule fragment screening with biolayer interferometry

David Mark, Xiaolei Zhang, Shirley Li, 2011, J. Comput. Aided Mol. Des..

Introducing Bayesian Thinking to High-Throughput Screening for False-Negative Rate Estimation

Lin Gao, Xin Wei, Xiaolei Zhang, 2013, Journal of biomolecular screening.

Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors.

Johannes C. Hermann, D. Carvajal, C. Lukacs, 2015, ACS medicinal chemistry letters.

A Novel Strategy for Identifying Non-covalent KRas Inhibitors

P. Tolias, M. Sabio, U. Gubler, 2020 .

Allosteric antibody inhibition of human hepsin protease.

P. Cramer, G. Georges, S. Hansen, 2012, The Biochemical journal.

Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target

E. Winzeler, M. Llinás, E. Istvan, 2023, Science Translational Medicine.

Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization

Thelma Thompson, David Fry, Kuo-Sen Huang, 2012, Proceedings of the National Academy of Sciences.

Kinetic Measurements of Cell Surface E-Selectin/Carbohydrate Ligand Interactions

Cheng Zhu, Mian Long, Hong Zhao, 2001, Annals of Biomedical Engineering.

Design of Libraries Targeting Protein–Protein Interfaces

Harald Mauser, Martin Stahl, Binh Vu, 2013, ChemMedChem.

Allosteric antibody inhibition of human hepsin protease.

P. Cramer, G. Georges, S. Hansen, 2012, The Biochemical journal.

Kinetic Measurements of Cell Surface E-Selectin/Carbohydrate Ligand Interactions

M. Long, Kuo-Sen Huang, Hong-yuan Zhao, 2001, Annals of Biomedical Engineering.