E. Parkin

发表

Dual Mechanisms for Shedding of the Cellular Prion Protein*

N. Hooper, A. Turner, E. Parkin, 2004, Journal of Biological Chemistry.

Structure-activity relationship of hydroxamate-based inhibitors on the secretases that cleave the amyloid precursor protein, angiotensin converting enzyme, CD23, and pro-tumor necrosis factor-alpha.

N. Hooper, R. Mayer, A. Faller, 2002, Biochemistry.

Structure−Activity Relationship of Hydroxamate-Based Inhibitors on the Secretases that Cleave the Amyloid Precursor Protein, Angiotensin Converting Enzyme, CD23, and Pro-Tumor Necrosis Factor-α†

N. Hooper, R. Mayer, A. Faller, 2002 .

ADAMs family members as amyloid precursor protein α‐secretases

N. Hooper, A. Turner, E. Parkin, 2003 .

ADAMs family members as amyloid precursor protein alpha-secretases.

N. Hooper, A. Turner, E. Parkin, 2003, Journal of neuroscience research.

Herpes simplex virus interferes with amyloid precursor protein processing

R. Itzhaki, E. Parkin, C. Dobson, 2005, BMC Microbiology.

The Amyloid Precursor Protein Represses Expression of Acetylcholinesterase in Neuronal Cell Lines*

N. Nalivaeva, A. Turner, E. Parkin, 2013, The Journal of Biological Chemistry.

Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein

E. Parkin, B. Harris, Isabel Pereira, 2009, Brain Research.

A disintegrin and metalloproteinase (ADAM)‐mediated ectodomain shedding of ADAM10

E. Parkin, B. Harris, 2009, Journal of neurochemistry.

Tumor Necrosis Factor-α Convertase (ADAM17) Mediates Regulated Ectodomain Shedding of the Severe-acute Respiratory Syndrome-Coronavirus (SARS-CoV) Receptor, Angiotensin-converting Enzyme-2 (ACE2)

N. Hooper, A. Turner, A. Smith, 2005, Journal of Biological Chemistry.

Zinc Metalloproteinases and Amyloid Beta-Peptide Metabolism: The Positive Side of Proteolysis in Alzheimer's Disease

E. Parkin, Mallory Gough, Catherine A. Parr-Sturgess, 2010, Biochemistry research international.

ZincMetalloproteinases and Amyloid Beta-Peptide Metabolism : The Positive Side of Proteolysis in Alzheimer ’ s Disease

E. Parkin, Mallory Gough, Catherine A. Parr-Sturgess, 2010 .

The E1 Copper Binding Domain of Full - Length Amyloid Precursor Protein Promotes Epithelial to Mesenchymal Transition in DU145 Cells in an Isoform - Specific Manner

Craig Delury, E. Parkin, Mallory Gough, 2015 .

Ectodomain shedding of the Notch ligand Jagged1 is mediated by ADAM17, but is not a lipid-raft-associated event.

D. Rushton, E. Parkin, Catherine A. Parr-Sturgess, 2010, The Biochemical journal.

Cellular prion protein regulates β-secretase cleavage of the Alzheimer's amyloid precursor protein

N. Hooper, C. Eckman, J. Manson, 2007, Proceedings of the National Academy of Sciences.

The role of proteolysis in Alzheimer's disease.

N. Hooper, E. Parkin, A. Trew, 2000, Advances in experimental medicine and biology.

The ectodomain shedding of angiotensin-converting enzyme is independent of its localisation in lipid rafts

N. Hooper, R. Skidgel, A. Turner, 2003, Journal of Cell Science.

Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase.

N. Hooper, E. Parkin, A. Turner, 2001, The Biochemical journal.

The Amyloid Precursor Protein Is Not Enriched in Caveolae‐Like, Detergent‐Insoluble Membrane Microdomains

N. Hooper, I. Hussain, A. Turner, 1997, Journal of neurochemistry.

The orphan drug dichloroacetate reduces amyloid beta-peptide production whilst promoting non-amyloidogenic proteolysis of the amyloid precursor protein

E. Parkin, Jessica E. Hammond, M. Hodges, 2021 .

Angiogenesis , Metastasis , and the Cellular Microenvironment Copper Modulates Zinc Metalloproteinase-Dependent Ectodomain Shedding of Key Signaling and Adhesion Proteins and Promotes the Invasion of Prostate Cancer Epithelial Cells

N. Clarke, Michael D Brown, C. Hart, 2012 .

the Invasion of Prostate Cancer Epithelial Cells Shedding of Key Signaling and Adhesion Proteins and Promotes Copper Modulates Zinc Metalloproteinase-Dependent Ectodomain

N. Clarke, Michael D Brown, C. Hart, 2012 .

Epithelial Cells Proteins and Promotes the Invasion of Prostate Cancer Ectodomain Shedding of Key Signaling and Adhesion Copper Modulates Zinc Metalloproteinase-Dependent

N. Clarke, Michael D Brown, C. Hart, 2012 .

Role of ADAMs in the Ectodomain Shedding and Conformational Conversion of the Prion Protein*

N. Hooper, A. Ashcroft, David R. Taylor, 2009, The Journal of Biological Chemistry.

A Point Mutation in the Juxtamembrane Stalk of Human Angiotensin I-converting Enzyme Invokes the Action of a Distinct Secretase*

N. Hooper, E. Sturrock, R. Jacob, 2001, The Journal of Biological Chemistry.

Cellular pion protein regulates beta-secretase cleavage of the Alzheimers amyloid precurs protein.

N. Hooper, C. Eckman, J. Manson, 2007 .

Differential Regulation of E-Cadherin Expression by the Soluble Ectodomain and Intracellular Domain of Jagged1

Craig Delury, E. Parkin, S. Broughton, 2013 .

Glycosylation and Glycosylphosphatidylinositol Membrane Anchors

N. Hooper, A. Turner, E. Parkin, 1997 .

A role for calcium and annexins in the formation of caveolae.

N. Hooper, E. Parkin, A. Turner, 1996, Biochemical Society transactions.

Osteonectin as a screening marker for pancreatic cancer: A prospective study

A. Papavassiliou, G. Sgourakis, D. Raptis, 2018, Journal of International Medical Research.

Modulation of phosphatidylcholine biosynthesis in celery by exogenous fatty acids.

C. Rolph, E. Parkin, 1999, Phytochemistry.

Phosphatidylcholine biosynthesis and cell growth in Apium graveolens

L. Goad, C. Rolph, E. Parkin, 1995 .

Development of a proteolytically stable retro-inverso peptide inhibitor of beta-amyloid oligomerization as a potential novel treatment for Alzheimer's disease.

D. Mann, M. Gobbi, D. Allsop, 2010, Biochemistry.

Pyruvate dehydrogenase kinase inhibition: Reversing the Warburg effect in cancer therapy

E. Parkin, H. Bell, 2016 .

Characterization of Detergent‐Insoluble Complexes Containing the Familial Alzheimer’s Disease‐Associated Presenilins

N. Hooper, E. Karran, I. Hussain, 1999, Journal of neurochemistry.

Angiotensin-converting enzyme as a GPIase: a critical reevaluation

N. Hooper, Lilia Leisle, A. Turner, 2005, Nature Medicine.

The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein.

N. Hooper, E. Sturrock, T. Condon, 2004, European journal of biochemistry.

BACE1 Overexpression Reduces SH-SY5Y Cell Viability Through a Mechanism Distinct from Amyloid-β Peptide Accumulation: Beta Prime-Mediated Competitive Depletion of sAβPPα.

Alexandre Benedetto, N. Dawson, E. Parkin, 2022, Journal of Alzheimer's disease : JAD.

Gene therapy-mediated enhancement of protective protein expression for the treatment of Alzheimer’s disease

Alexandre Benedetto, C. Gaffney, N. Dawson, 2021, Brain Research.

Membrane raft actin deficiency and altered Ca2+-induced vesiculation in stomatin-deficient overhydrated hereditary stomatocytosis.

E. J. Turner, N. Hooper, G. Stewart, 2008, Biochimica et biophysica acta.

Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein.

N. Hooper, E. Parkin, A. Turner, 1999, The Biochemical journal.

Stroma-induced Jagged1 expression drives PC3 prostate cancer cell migration; disparate effects of RIP-generated proteolytic fragments on cell behaviour and Notch signaling.

N. Clarke, Craig Delury, Michael D Brown, 2016, Biochemical and biophysical research communications.

Secretase-mediated cell surface shedding of the angiotensin-converting enzyme.

N. Hooper, A. Turner, E. Parkin, 2004, Protein and peptide letters.

The histidine composition of the amyloid-β domain, but not the E1 copper binding domain, modulates β-secretase processing of amyloid-β protein precursor in Alzheimer's disease.

E. Parkin, Mallory Gough, S. Blanthorn-Hazell, 2014, Journal of Alzheimer's disease : JAD.

Isolation and characterization of two distinct low-density, Triton-insoluble, complexes from porcine lung membranes.

N. Hooper, E. Parkin, A. Turner, 1996, The Biochemical journal.

The E1 copper binding domain of full-length amyloid precursor protein mitigates copper-induced growth inhibition in brain metastatic prostate cancer DU145 cells

Craig Delury, E. Parkin, Mallory Gough, 2014, Biochemical and Biophysical Research Communications - BBRC.

The E1 copper binding domain of full-length amyloid precursor protein mitigates copper-induced growth inhibition in brain metastatic prostate cancer DU145 cells

Craig Delury, E. Parkin, Mallory Gough, 2014, Biochemical and biophysical research communications.