N. Watt

发表

Dual Mechanisms for Shedding of the Cellular Prion Protein*

N. Hooper, A. Turner, E. Parkin, 2004, Journal of Biological Chemistry.

Reduced insulin and IGF-1 signalling synergistically extend healthspan in male mice

N. Yuldasheva, M. Kearney, R. Cubbon, 2019, bioRxiv.

PTPRD and DCC Are Novel BACE1 Substrates Differentially Expressed in Alzheimer’s Disease: A Data Mining and Bioinformatics Study

K. Simmons, P. Meakin, N. Watt, 2022, International journal of molecular sciences.

Cellular prion protein regulates β-secretase cleavage of the Alzheimer's amyloid precursor protein

N. Hooper, C. Eckman, J. Manson, 2007, Proceedings of the National Academy of Sciences.

The prion protein and neuronal zinc homeostasis.

N. Hooper, N. Watt, 2003, Trends in biochemical sciences.

Cixutumumab reveals a critical role for IGF-1 in adipose and hepatic tissue remodelling during the development of diet-induced obesity

N. Yuldasheva, M. Kearney, K. Simmons, 2022, Adipocyte.

Inorganic Nitrate Promotes Glucose Uptake and Oxidative Catabolism in White Adipose Tissue Through the XOR-Catalyzed Nitric Oxide Pathway

J. Griffin, M. Kearney, R. Cubbon, 2020, Diabetes.

Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle

J. Griffin, Ben D. McNally, R. Bauer, 2022, Nature Communications.

α-cleavage of the prion protein occurs in a late compartment of the secretory pathway and is independent of lipid rafts

N. Hooper, David R. Taylor, A. Walmsley, 2009, Molecular and Cellular Neuroscience.

Reactive Oxygen Species-mediated β-Cleavage of the Prion Protein in the Cellular Response to Oxidative Stress*

N. Hooper, David R. Taylor, Daniel A. Thomas, 2005, Journal of Biological Chemistry.

Protective effect of prion protein via the N‐terminal region in mediating a protective effect on paraquat‐induced oxidative injury in neuronal cells

B. Elmoualij, N. Hooper, O. Pierard, 2008, Journal of neuroscience research.

Endothelial Insulin Receptors Promote VEGF-A Signaling via ERK1/2 and Sprouting Angiogenesis

N. Yuldasheva, P. Carmeliet, M. Kearney, 2021, Endocrinology.

Neuronal zinc regulation and the prion protein

N. Hooper, N. Watt, Heledd H. Griffiths, 2013, Prion.

Cellular pion protein regulates beta-secretase cleavage of the Alzheimers amyloid precurs protein.

N. Hooper, C. Eckman, J. Manson, 2007 .

Assigning functions to distinct regions of the N-terminus of the prion protein that are involved in its copper-stimulated, clathrin-dependent endocytosis

N. Hooper, David R. Taylor, N. Watt, 2005, Journal of Cell Science.

Reactive oxygen species (ROS)-mediated β-cleavage of the prion protein in the mechanism of the cellular response to oxidative stress

N. Hooper, N. Watt, 2005 .

The response of neurones and glial cells to elevated copper

N. Hooper, N. Watt, 2001, Brain Research Bulletin.

Reactive oxygen species-mediated beta-cleavage of the prion protein in the cellular response to oxidative stress.

N. Hooper, David R. Taylor, Daniel A. Thomas, 2005, The Journal of biological chemistry.

Prion protein facilitates uptake of zinc into neuronal cells

N. Hooper, David R. Taylor, J. Rushworth, 2012, Nature Communications.

Mechanism of the metal-mediated endocytosis of the prion protein.

N. Hooper, David R. Taylor, N. Watt, 2008, Biochemical Society transactions.

The Role of Zinc in Alzheimer's Disease

N. Hooper, N. Watt, I. J. Whitehouse, 2010, International journal of Alzheimer's disease.

Prion Protein-mediated Toxicity of Amyloid-β Oligomers Requires Lipid Rafts and the Transmembrane LRP1*

N. Hooper, J. Rushworth, N. Watt, 2013, The Journal of Biological Chemistry.

Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance-related vascular damage

A. Maqbool, N. Yuldasheva, A. Shah, 2020, American journal of physiology. Cell physiology.

Lipid rafts: linking prion protein to zinc transport and amyloid-β toxicity in Alzheimer's disease

N. Hooper, N. Watt, Heledd H. Griffiths, 2014, Front. Cell Dev. Biol..

Reactive oxygen species (ROS)-mediated beta-cleavage of the prion protein in the mechanism of the cellular response to oxidative stress.

N. Hooper, N. Watt, 2005, Biochemical Society transactions.

Cellular prion protein protects against reactive-oxygen-species-induced DNA damage.

N. Hooper, C. Wild, M. Routledge, 2007, Free radical biology & medicine.

Linking the unfolded protein response to bioactive lipid metabolism and signalling in the cell non‐autonomous extracellular communication of ER stress

N. Watt, L. Roberts, Anna McGrane, 2023, BioEssays : news and reviews in molecular, cellular and developmental biology.

Prion protein and Alzheimer's disease

N. Hooper, N. Watt, 2007 .

Paracrine role for endothelial IGF-1 receptor in white adipocyte beiging

N. Yuldasheva, M. Kearney, K. Simmons, 2021, bioRxiv.

Tethering the N‐terminus of the prion protein compromises the cellular response to oxidative stress

N. Hooper, A. Walmsley, N. Watt, 2003, Journal of neurochemistry.

1 PRION PROTEIN-MEDIATED TOXICITY OF AMYLOID-β OLIGOMERS REQUIRES LIPID RAFTS AND THE TRANSMEMBRANE LRP 1

N. Hooper, J. Rushworth, N. Watt, 2013 .

Factors Affecting the Unplanned Hospital Readmission of Elderly Patients with Cardiovascular Disease

B. J. McConnell, J. McElnay, M. Scott, 2001 .

Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase–Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance

N. Yuldasheva, S. Schurmans, M. Kearney, 2017, Diabetes.

Endothelial IGF‐1 receptor mediates crosstalk with the gut wall to regulate microbiota in obesity

N. Yuldasheva, I. Teh, J. Boyle, 2021, EMBO reports.