H. Iwata

发表

Distinctive Expression Patterns of Heparan Sulfate O-Sulfotransferases and Regional Differences in Heparan Sulfate Structure in Chick Limb Buds*

Hiroaki Suzuki, K. Kimata, H. Habuchi, 2004, Journal of Biological Chemistry.

Relationship of matrix metalloproteinases and their inhibitors to cartilage proteoglycan and collagen turnover: analyses of synovial fluid from patients with osteoarthritis.

N. Ishiguro, H. Iwata, A. Robin Poole, 1999, Arthritis and rheumatism.

TNF-α-Dependent Activation of NF-κB in Human Osteoblastic HOS-TE85 Cells Is Repressed in Vector-Averaged Gravity Using Clinostat Rotation

H. Seo, R. Gruener, F. Kambe, 2000 .

Tumor Necrosis Factor α Induces Expression of Genes for Matrix Degradation in Human Chondrocyte‐like HCS‐2/8 Cells Through Activation of NF‐κB: Abrogation of the Tumor Necrosis Factor α Effect by Proteasome Inhibitors

H. Seo, F. Kambe, M. Takigawa, 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Distraction Osteogenesis Enhanced by Osteoblastlike Cells and Collagen Gel

N. Ishiguro, H. Kitoh, T. Kitakoji, 2002, Clinical orthopaedics and related research.

Comparative studies on effect of risedronate and alfacalcidol against glucocorticoid-induced osteoporosis in rheumatoid arthritic patients.

T. Toriyama, T. Nakajima, H. Iwata, 2007, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Detection of stromelysin in synovial fluid and serum from patients with rheumatoid arthritis and osteoarthritis

N. Ishiguro, K. Obata, Naoki Ishiguro, 1994, Clinical Rheumatology.

Negative prognostic impact of renal replacement therapy in adult living-donor liver transplant recipients: preoperative recipient condition and donor factors.

K. Shiraki, Y. Takei, K. Sugimoto, 2014, Transplantation proceedings.

The SHAP-HA complex in sera from patients with rheumatoid arthritis and osteoarthritis.

N. Ishiguro, K. Kimata, H. Iwata, 1999, The Journal of rheumatology.

Characterization of gene expression induced by RET with MEN2A or MEN2B mutation.

M. Ichihara, Y. Murakumo, Masahide Takahashi, 2002, The American journal of pathology.

The activity of dipeptidyl peptidase II and dipeptidyl peptidase IV in mice immunized with type II collagen.

T. Nagatsu, H. Iwata, K. Fujita, 1992, Biochemical medicine and metabolic biology.

Activities of dipeptidyl peptidase II, dipeptidyl peptidase IV, prolyl endopeptidase, and collagenase-like peptidase in synovial membrane from patients with rheumatoid arthritis and osteoarthritis.

T. Nagatsu, H. Iwata, T. Miura, 1991, Biochemical medicine and metabolic biology.

Activities of dipeptidyl peptidase II and dipeptidyl peptidase IV in synovial fluid from patients with rheumatoid arthritis and osteoarthritis.

T. Nagatsu, H. Iwata, T. Miura, 1989, Clinical chemistry.

The occurrence of a wide variety of dermatan sulfate-chondroitin sulfate copolymers in fibrous cartilage.

T. Yamagata, S. Suzuki, H. Habuchi, 1973, The Journal of biological chemistry.

Properties of Functionally Gradient Composite Consisting of Hydroxyapatite Containing Glass Coated Titanium and Characters for Bioactive Implant

S. Ban, S. Maruno, H. Iwata, 1992 .

Effects of Glucocorticoids on Tumor Necrosis Factor α‐Dependent Activation of Nuclear Factor κB and Expression of the Intercellular Adhesion Molecule 1 Gene in Osteoblast‐Like ROS17/2.8 Cells

H. Seo, F. Kambe, N. Ishiguro, 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Demineralized bone matrix and native bone morphogenetic protein in orthopaedic surgery.

T. Bauer, S. Sakano, H. Iwata, 2002, Clinical orthopaedics and related research.

Abnormal occurrence of a large chondroitin sulfate proteoglycan, PG-M/versican in osteoarthritic cartilage.

Y. Nishida, K. Kimata, H. Iwata, 1994, Osteoarthritis and cartilage.

Unusual Back Pain Caused by Intervertebral Disc Degeneration Associated With Schmorl Node at Th11/12 in a Young Athlete, Successfully Treated by Anterior Interbody Fusion: A Case Report

K. Shimizu, K. Miyamoto, A. Iwata, 2009, Spine.

Low-selenium diet, bone, and articular cartilage in rats.

N. Ishiguro, H. Iwata, O. Habuchi, 1994, Nutrition.

TNF‐α Increases Expression of IL‐6 and ICAM‐1 Genes Through Activation of NF‐κB in Osteoblast‐like ROS17/2.8 Cells

H. Seo, F. Kambe, N. Ishiguro, 1998 .

Effect of high-molecular-weight sodium hyaluronate on immobilized rabbit knee.

H. Iwata, T. Miura, H. Itoh, 1994, Clinical orthopaedics and related research.

Prevention of bone loss by percutaneous estradiol implants in ovariectomized rats.

T. Nabeshima, T. Yotsuyanagi, H. Iwata, 1995, Journal of biomedical materials research.

Matrix metalloproteinases, tissue inhibitors of metalloproteinases, and glycosaminoglycans in synovial fluid from patients with rheumatoid arthritis.

N. Ishiguro, K. Miyazaki, H. Iwata, 1999, The Journal of rheumatology.

Collagen and alkaline phosphatase gene expression during bone morphogenetic protein (BMP)-induced cartilage and bone differentiation.

Y. Murata, K. Sato, S. Sakano, 1993, Clinical orthopaedics and related research.

Bone morphogenetic protein-induced muscle- and synovium-derived cartilage differentiation in vitro.

T. Sato, H. Iwata, K. Sato, 1993, Clinical orthopaedics and related research.

Increased pentosidine, an advanced glycation end product, in plasma and synovial fluid from patients with rheumatoid arthritis and its relation with inflammatory markers.

M. Nangaku, T. Miyata, K. Kurokawa, 1998, Biochemical and biophysical research communications.

Relationships of matrix metalloproteinases and their inhibitors to cartilage proteoglycan and collagen turnover and inflammation as revealed by analyses of synovial fluids from patients with rheumatoid arthritis.

A. Poole, T. Kojima, N. Ishiguro, 2001, Arthritis and rheumatism.

The expression of matrix metalloproteinases and inhibitors in acute rupture of the anterior cruciate ligament

T. Kojima, N. Ishiguro, H. Iwata, 2000, Modern rheumatology.

mRNA expression of matrix metalloproteinases and tissue inhibitors of metalloproteinase in interface tissue around implants in loosening total hip arthroplasty.

I. Nagaya, N. Ishiguro, Y. Hasegawa, 1996, Journal of biomedical materials research.

Rapid one-step sandwich enzyme immunoassay for tissue inhibitor of metalloproteinases. An application for rheumatoid arthritis serum and plasma.

K. Iwata, K. Yamashita, H. Iwata, 1990, Journal of immunological methods.

Anticancer effects of adriamycin-loaded hydroxyapatite implants determined in a Swarm rat chondrosarcoma model.

T. Nabeshima, T. Yotsuyanagi, H. Iwata, 1994, Japanese journal of pharmacology.

The covalent complex formation of hyaluronan with heavy chains of inter-α-trypsin inhibitor family is important for its functions

K. Kimata, M. Yoneda, Naoki Ishiguro, 2002 .

Determination of stromelysin-1, 72 and 92 kDa type IV collagenase, tissue inhibitor of metalloproteinase-1 (TIMP-1), and TIMP-2 in synovial fluid and serum from patients with rheumatoid arthritis.

N. Fujimoto, N. Ishiguro, K. Obata, 1996, The Journal of rheumatology.

Characterization of the glycosphingolipids of pig cortical bone and cartilage.

T. Yamagata, M. Ito, H. Iwata, 1989, Biochimica et biophysica acta.

Collagenase-like (CL) peptidase activity in synovial fluid from patients with rheumatoid arthritis.

T. Nagatsu, H. Iwata, T. Miura, 1987, Clinica chimica acta; international journal of clinical chemistry.

Occurrence of PG-Lb, a leucine-rich small chondroitin/dermatan sulphate proteoglycan in mammalian epiphyseal cartilage: molecular cloning and sequence analysis of the mouse cDNA.

K. Kurita, K. Kimata, M. Zako, 1996, The Biochemical journal.

Synthesis of antibiotic-loaded hydroxyapatite beads and in vitro drug release testing.

T. Yotsuyanagi, H. Iwata, K. Yamamura, 1992, Journal of biomedical materials research.

TISSUE INHIBITOR OF METALLOPROTEINASES AND COLLAGENASE ACTIVITY IN SYNOVIAL FLUID OF HUMAN RHEUMATOID ARTHRITIS

K. Iwata, K. Yamashita, H. Iwata, 1991 .

Uptake of glycosaminoglycan polysulfate by articular and meniscus cartilage: a biochemical and autoradiographic investigation.

H. Iwata, G. Kajino, M. Kaneko, 1980, Clinical orthopaedics and related research.

The retention of abnormal type I procollagen and correlated expression of HSP 47 in fibroblasts from a patient with lethal osteogenesis imperfecta

S. Saga, T. Kojima, N. Ishiguro, 1998, The Journal of pathology.

Alteration of the kinetics of type I procollagen synthesis in human osteosarcoma cells by 1,25‐dihydroxyvitamin D3

S. Saga, T. Kojima, N. Ishiguro, 1997, Journal of cellular biochemistry.

Alterations of proteoglycan synthesis in rabbit articular cartilage induced by intra-articular injection of papain.

K. Tokuyasu, H. Iwata, S. Miyauchi, 1993, Osteoarthritis and cartilage.

Correction of abnormal matrix formed by cmd/cmd chondrocytes in culture by exogenously added cartilage proteoglycan

S. Suzuki, K. Kimata, H. Iwata, 1986, The Journal of cell biology.

The effect of egg phosphatidylcholine on antibiotics retention and release from hydroxyapatite

H. Iwata, K. Yamamura, X. Zhao, 1992 .

Sensitivity of Osteoinductive Activity of Demineralized and Defatted Rat Femur to Temperature and Duration of Heating

Y. Murata, H. Sugiura, S. Sakano, 1995, Clinical orthopaedics and related research.

Surgical excision of hemophilic pseudotumor of the ilium.

N. Ishiguro, T. Kamiya, H. Iwata, 1992, Clinical orthopaedics and related research.

Rapidly destructive arthropathy of the hip in haemophilia

J. Takamatsu, N. Ishiguro, H. Iwata, 2001, Haemophilia : the official journal of the World Federation of Hemophilia.

Rapidly destructive arthropathy of the hip in haemophilia.

J. Takamatsu, N. Ishiguro, H. Iwata, 2001 .

Effects of sodium hyaluronate on experimental osteoarthritis in rabbit knee joints.

N. Ishiguro, H. Iwata, T. Ito, 1999, Nagoya journal of medical science.

Hemophilic arthropathy of the elbow.

N. Ishiguro, H. Iwata, S. Yasuo, 1995, Journal of pediatric orthopedics.

Pharmacologic and clinical aspects of intraarticular injection of hyaluronate.

H. Iwata, 1993, Clinical orthopaedics and related research.

Immunogenicity of hylan g-f 20 in Guinea pigs and mice.

Masanori Sasaki, Toyomi Takahashi, H. Iwata, 2004, The Journal of rheumatology.

Tumor necrosis factor alpha induces expression of genes for matrix degradation in human chondrocyte-like HCS-2/8 cells through activation of NF-kappaB: abrogation of the tumor necrosis factor alpha effect by proteasome inhibitors.

H. Seo, F. Kambe, M. Takigawa, 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Bone bonding behavior of the hydroxyapatite containing glass-titanium composite prepared by the Cullet method.

H Iwata, S. Maruno, H. Iwata, 2001, Biomaterials.

Bone morphogenesis in implants of insoluble bone gelatin.

M. Urist, R. McDowell, H. Iwata, 1973, Proceedings of the National Academy of Sciences of the United States of America.

Preservation and biodegradation of the morphogenetic property of bone matrix.

M. Urist, H. Iwata, 1973, Journal of theoretical biology.

Osteogenesis in sintered bone combined with bovine bone morphogenetic protein.

H. Iwata, K. Sato, T. Miura, 1993, Clinical orthopaedics and related research.

Bone morphogenesis in implants of residues of radioisotope labelled bone matrix

M. Urist, K. M. Kimball, H. Iwata, 2005, Calcified Tissue Research.

OBSERVATIONS IMPLICATING AN EXTRACELLULAR ENZYMIC MECHANISM OF CONTROL OF BONE MORPHOGENESIS

M. Urist, H. Iwata, P. L. Ceccotti, 1974, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Chemosterilized autolyzed antigen-extracted allogeneic (AAA) bone matrix gelatin for repair of defects from excision of benign bone tumors: a preliminary report.

K. Ida, H. Iwata, H. Hanamura, 1981, Clinical orthopaedics and related research.

Solubilized bone morphogenetic protein (BMP) from mouse osteosarcoma and rat demineralized bone matrix.

M. Urist, H. Iwata, M. Nakagawa, 1980, Clinical orthopaedics and related research.

Protein polysaccharide of bone morphogenetic matrix.

M. Urist, H. Iwata, 1972, Clinical orthopaedics and related research.

A study of the bone morphogenetic protein derived from bovine demineralized dentin matrix.

H. Iwata, H. Mizutani, M. Ueda, 1996, Nagoya journal of medical science.

Chondroosteogenetic response to crude bone matrix proteins bound to hydroxyapatite.

H. Iwata, K. Sato, T. Miura, 1987, Clinical orthopaedics and related research.

Solubilization and purification of bone morphogenetic protein (BMP) from Dunn osteosarcoma.

M. Urist, H. Iwata, M. Nakagawa, 1980, Clinical orthopaedics and related research.

Antitumor effects and distribution of adriamycin incorporated into hydroxyapatite implants in a cancer rat model bearing swarm rat chondrosarcoma.

T. Nabeshima, T. Yotsuyanagi, H. Iwata, 1994, Japanese journal of pharmacology.

Enhanced expression of fibronectin by cmd/cmd chondrocytes and its modulation by exogenously added proteoglycan.

S. Suzuki, K. Kimata, T. Tsukahara, 1991, Journal of cell science.

Arthrodesis of the ankle joint with rheumatoid arthritis: experience with the transfibular approach.

H. Iwata, Y. Sugiura, M. Kaneko, 1980, Clinical orthopaedics and related research.

TNF-alpha increases expression of IL-6 and ICAM-1 genes through activation of NF-kappaB in osteoblast-like ROS17/2.8 cells.

H. Seo, F. Kambe, N. Ishiguro, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Macrophage activation and migration in interface tissue around loosening total hip arthroplasty components.

H Iwata, S. Saga, T. Kojima, 1997, Journal of biomedical materials research.

The immunosuppressive effect of fresh allogeneic bone graft in mice

I. Nakashima, N. Ishiguro, H. Iwata, 1997, International Orthopaedics.

Analysis of Chondrex (YKL-40, HC gp-39) in the Cerebrospinal Fluid of Patients With Spine Disease

Y. Matsuyama, Y. Hasegawa, T. Tsuji, 2002, Spine.

Basic Fibroblast Growth Factor Has a Beneficial Effect on the Viability of Random Skin Flaps in Rats

Naoki Ishiguro, H. Iwata, Y. Yabe, 1994, Annals of plastic surgery.

The effect of da-fang-feng-tang on treatment of type II collagen-induced arthritis in DBA/1 mice.

H Iwata, N. Ishiguro, K. Sato, 1999, The American journal of Chinese medicine.

Effect of Chondroitinase ABC on Matrix Metalloproteinases and Inflammatory Mediators Produced by Intervertebral Disc of Rabbit In Vitro

N. Fujii, Toyomi Takahashi, H. Iwata, 2002, Spine.

Detection and purification of an abnormal protein from plasma of patients with rheumatoid arthritis.

K. Maeda, K. Ohta, N. Yamanaka, 1988, Clinica chimica acta; international journal of clinical chemistry.

Serum cartilage‐derived retinoic acid‐sensitive protein (CD‐RAP) levels in Swarm rat chondrosarcoma

S. Kondo, H. Sugiura, Kenji Kobayashi, 2002, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Nature of bone morphogenetic protein (BMP) from decalcified rabbit bone matrix.

S. Takahashi, H. Iwata, H. Hanamura, 1987, Nihon Seikeigeka Gakkai zasshi.

Hyaluronic acid production and removal during bone morphogenesis in implants of bone matrix in rats.

M. Urist, H. Iwata, 1973, Clinical orthopaedics and related research.

Abnormal collagen fibrillogenesis in epiphyseal cartilage of CMD (cartilage matrix deficiency) mouse.

M. Kobayakawa, K. Kimata, H. Iwata, 1985, Collagen and related research.

Protooncogene expression in osteogenesis induced by bone morphogenetic protein.

Y. Murata, K. Sato, S. Sakano, 1997, Clinical orthopaedics and related research.

Uni‐axial cyclic stretch induces the activation of transcription factor nuclear factor κB in human fibroblast cells

K. Naruse, M. Sokabe, N. Ishiguro, 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Effects of high-molecular-weight sodium hyaluronate on experimental osteoarthrosis induced by the resection of rabbit anterior cruciate ligament.

H. Iwata, T. Obara, T. Miura, 1994, Clinical orthopaedics and related research.

Analysis of cartilage-derived retinoic-acid-sensitive protein (CD-RAP) in synovial fluid from patients with osteoarthritis and rheumatoid arthritis.

N. Ishiguro, Y. Hasegawa, L. Sandell, 2002, The Journal of bone and joint surgery. British volume.

Ocular anti-inflammatory and systemic immunosuppressive effects of topically applied fluorometholone.

H. Iwata, T. Iso, H. Yamauchi, 1979, Japanese Journal of Pharmacology.

Serum collagenase-like peptidase activity correlated with bone mineral density. A study of 102 elderly women.

T. Nagatsu, H. Iwata, A. Harada, 1993, Acta orthopaedica Scandinavica.

Bone morphogenetic protein and proteinase in the guinea pig.

M. Urist, B. Strates, H. Iwata, 1972, Clinical orthopaedics and related research.

Molecular Heterogeneity of the SHAP-Hyaluronan Complex

M. Mörgelin, K. Kimata, M. Yoneda, 2003, Journal of Biological Chemistry.

Activity of dipeptidyl peptidase IV and post-proline cleaving enzyme in sera from osteoporotic patients.

T. Nagatsu, H. Iwata, T. Miura, 1988, Clinical chemistry.

Selective Neutrophil Depletion with Monoclonal Antibodies Attenuates Ischemia/Reperfusion Injury in Skeletal Muscle

Takuya Shimizu, N. Ishiguro, Naoki Ishiguro, 1998, Journal of reconstructive microsurgery.

Osteoclast induction from bone marrow cells is due to pro-inflammatory mediators from macrophages exposed to polyethylene particles: a possible mechanism of osteolysis in failed THA.

N. Ishiguro, H. Iwata, S. Kondo, 2001, Journal of biomedical materials research.

Thermal and Electrical Transport Properties of Porous Si Thin Films

K. Miyazaki, H. Iwata, H. Hagino, 2015 .

Examination of synovial fluid and serum hyaluronidase activity as a joint marker in rheumatoid arthritis and osteoarthritis patients (by zymography)

Y. Hasegawa, Haruo Ito, H. Iwata, 1999, Annals of the rheumatic diseases.

Characterization and Biological Application of Hydroxyapatite-Glass-Titanium (HA-G-Ti) Functional Gradient Composite Material

Kenji Yamada, N. Ishiguro, Y. Hasegawa, 1999 .

Heat tolerance of activity toward ectopic bone formation by rabbit bone matrix protein.

T. Sato, H. Iwata, M. Takahashi, 1993, Annales chirurgiae et gynaecologiae. Supplementum.

Chemosterilized autolyzed antigen-extracted allogeneic (AAA) bone matrix gelatin for repair of defects from excision of bone tumors

H. Iwata, 1981 .

Up-regulation of COX2 expression by uni-axial cyclic stretch in human lung fibroblast cells.

Keiji Naruse, T. Kojima, N. Ishiguro, 1998, Biochemical and biophysical research communications.

Effect of hydroxyapatite containing glass coating on the bonding between bone and titanium implants

S. Maruno, H. Iwata, H. Itoh, 1993 .

Bone morphogenesis of rabbit bone morphogenetic protein-bound hydroxyapatite-fibrin composite.

T. Sato, K. Sato, H. Iwata, 1991, Clinical orthopaedics and related research.

Characterization and Stability of Bioactive HA-G-Ti Composite Materials and Bonding to Bone

S. Ban, T. Hanaichi, S. Maruno, 1994 .

Cartilaginous transdifferentiation of rat tenosynovial cells under the influence of bone morphogenetic protein in tissue culture.

K. Sato, H. Iwata, T. Miura, 1988, Clinical orthopaedics and related research.

Effect of Elevated Temperature on Experimental Swarm Rat Chondrosarcoma

H. Sugiura, S. Sakano, H. Iwata, 1995, Clinical orthopaedics and related research.

TNF-alpha-dependent activation of NF-kappa B in human osteoblastic HOS-TE85 cells is repressed in vector-averaged gravity using clinostat rotation.

H. Seo, R. Gruener, F. Kambe, 2000, Biochemical and biophysical research communications.

Micro-observation and characterization of bonding between bone and HA-glass-titanium functionally gradient composite.

T. Ishikawa, S. Ban, S. Maruno, 1991, Biomaterials.

The role of prostaglandins in experimental ocular inflammations

H. Iwata, T. Iso, H. Yamauchi, 1979, Agents and Actions.

Genetic association between rheumatoid arthritis and estrogen receptor microsatellite polymorphism.

H. Iwata, H. Takagi, T. Kanamono, 2000, The Journal of rheumatology.

Effects of bisphosphonate on bone metabolism in tail-suspended rats.

Y. Murata, S. Ohmori, H. Iwata, 1996, Environmental medicine : annual report of the Research Institute of Environmental Medicine, Nagoya University.

Differential display analysis of murine collagen‐induced arthritis: cloning of the cDNA‐encoding murine ATPase inhibitor

I. Nakashima, N. Ishiguro, H. Iwata, 1997, Immunology.