S. Michel

Epigenetics and allergy: from basic mechanisms to clinical applications.

Harald Renz, J. Tost, H. Renz, 2017, Epigenomics.

Preventing ATP Degradation by ASO-Mediated Knockdown of CD39 and CD73 Results in A2aR-Independent Rescue of T Cell Proliferation

R. Klar, J. Festag, S. Michel, 2020, Molecular therapy. Nucleic acids.

ANGPTL4 silencing via antisense oligonucleotides reduces plasma triglycerides and glucose in mice without causing lymphadenopathy

S. Kersten, G. Olivecrona, Masoumeh Motamedi Joibari, 2022, Journal of lipid research.

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

D. Munn, S. Mehrotra, D. Marchion, 2019, Nature Communications.

Loss of diphthamide pre-activates NF-κB and death receptor pathways and renders MCF7 cells hypersensitive to tumor necrosis factor

I. Pastan, U. Brinkmann, T. Racek, 2015, Proceedings of the National Academy of Sciences.

A highly efficient modality to block the degradation of tryptophan for cancer immunotherapy: locked nucleic acid-modified antisense oligonucleotides to inhibit human indoleamine 2,3-dioxygenase 1/tryptophan 2,3-dioxygenase expression

A. Zippelius, R. Klar, S. Michel, 2019, Cancer Immunology, Immunotherapy.

Development and characterization of DNAzyme candidates demonstrating significant efficiency against human rhinoviruses

C. Bachert, N. Papadopoulos, S. Johnston, 2018, The Journal of allergy and clinical immunology.

Antisense oligonucleotide targeting CD39 improves anti-tumor T cell immunity

A. Zippelius, R. Klar, J. Festag, 2019, Journal of Immunotherapy for Cancer.