Jason R. Thonhoff

发表

Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis

S. Appel, D. Beers, Weihua Zhao, 2020, Scientific Reports.

Compatibility of human fetal neural stem cells with hydrogel biomaterials in vitro

Jason R. Thonhoff, Dianne I. Lou, Paivi M. Jordan, 2008, Brain Research.

Identification of early disease progression in an ALS rat model

Jason R. Thonhoff, P. M. Jordan, J. R. Karam, 2007, Neuroscience Letters.

Extracellular Vesicles Derived From Ex Vivo Expanded Regulatory T Cells Modulate In Vitro and In Vivo Inflammation

S. Appel, D. Beers, Weihua Zhao, 2022, Frontiers in Immunology.

Mutant SOD1 microglia-generated nitroxidative stress promotes toxicity to human fetal neural stem cell-derived motor neurons through direct damage and noxious interactions with astrocytes.

Junling Gao, Jason R. Thonhoff, Ping Wu, 2012, American journal of stem cells.

ALS patients' regulatory T lymphocytes are dysfunctional, and correlate with disease progression rate and severity.

E. Shpall, S. Appel, D. Beers, 2017, JCI insight.

Modulation of spontaneous motor unit potentials by a new motor cortical magnetic stimulation method in amyotrophic lateral sclerosis

D. Rosenfield, S. Helekar, S. Appel, 2022, Journal of Neurology.

Combined Regulatory T-Lymphocyte and IL-2 Treatment Is Safe, Tolerable, and Biologically Active for 1 Year in Persons With Amyotrophic Lateral Sclerosis

S. Paganoni, M. Cudkowicz, S. Appel, 2022, Neurology: Neuroimmunology & Neuroinflammation.

Neuroinflammatory mechanisms in amyotrophic lateral sclerosis pathogenesis

S. Appel, E. Simpson, Jason R. Thonhoff, 2018, Current opinion in neurology.

Tregs Attenuate Peripheral Oxidative Stress and Acute Phase Proteins in ALS

S. Appel, D. Beers, Weihua Zhao, 2022, Annals of neurology.

Serum programmed cell death proteins in amyotrophic lateral sclerosis

S. Appel, D. Beers, Weihua Zhao, 2021, Brain, behavior, & immunity - health.

Expanded autologous regulatory T-lymphocyte infusions in ALS

M. Cudkowicz, J. Berry, S. Appel, 2018, Neurology: Neuroimmunology & Neuroinflammation.

Modulation of spontaneous motor unit potentials by a new motor cortical magnetic stimulation method in amyotrophic lateral sclerosis

D. Rosenfield, S. Helekar, S. Appel, 2022, Journal of Neurology.

Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer’s disease

J. Masdeu, Hong Zhao, S. Appel, 2022, Acta Neuropathologica Communications.

Human Neural Stem Cell Transplantation-Mediated Alteration of Microglial/Macrophage Phenotypes after Traumatic Brain Injury

D. Prough, D. Dewitt, Junling Gao, 2016, Cell transplantation.

Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls

C. Svendsen, L. Ornelas, H. Goodridge, 2020, iScience.

Increased activation ability of monocytes from ALS patients

S. Appel, Weihua Zhao, Jinghong Wang, 2020, Experimental Neurology.

Functional alterations of myeloid cells during the course of Alzheimer’s disease

J. Masdeu, B. Pascual, S. Appel, 2018, Molecular Neurodegeneration.

Critical Role of PI3K/Akt/GSK3β in Motoneuron Specification from Human Neural Stem Cells in Response to FGF2 and EGF

Junling Gao, Kristopher G. Hooten, Jason R. Thonhoff, 2011, PloS one.

Restoring regulatory T-cell dysfunction in Alzheimer’s disease through ex vivo expansion

J. Masdeu, B. Pascual, S. Appel, 2020, Brain communications.

Stem cell-derived motor neurons: applications and challenges in amyotrophic lateral sclerosis.

Jason R. Thonhoff, Ping Wu, Luis Ojeda, 2009, Current stem cell research & therapy.

Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson’s disease

S. Appel, E. Lai, D. Beers, 2021, NPJ Parkinson's disease.

Critical role of PI 3 K / Akt / GSK 3 β in motoneuron specification from human neural stem cells in response to FGF 2 and EGF

Junling Gao, Kristopher G. Hooten, Jason R. Thonhoff, 2017 .

Lipoic acid enhances survival of transplanted neural stem cells by reducing transplantation-associated injury

Junling Gao, Jason R. Thonhoff, Ping Wu, 2013, Journal of neurorestoratology.

Generation of spinal motor neurons from human fetal brain‐derived neural stem cells: Role of basic fibroblast growth factor

Junling Gao, D. Boehning, Jason R. Thonhoff, 2009, Journal of neuroscience research.

Multifocal Noninvasive Magnetic Stimulation of the Primary Motor Cortex in Type 1 Myotonic Dystrophy -A Proof of Concept Pilot Study.

D. Rosenfield, S. Helekar, Jason R. Thonhoff, 2021, Journal of neuromuscular diseases.

Functional alterations of myeloid cells during the course of Alzheimer’s disease

J. Masdeu, B. Pascual, S. Appel, 2018, Molecular Neurodegeneration.

Safety and efficacy of rozanolixizumab in patients with generalised myasthenia gravis (MycarinG): a randomised, double-blind, placebo-controlled, adaptive phase 3 study

Denny J. Padgett, Adam L. Comer, Yi-Chung Lee, 2023, The Lancet Neurology.

Immunological, oxidative, and structural factors and their responses to regulatory t lymphocyte therapy in amyotrophic lateral sclerosis

S. Appel, D. Beers, Weihua Zhao, 2023, Ageing and Neurodegenerative Diseases.

A phase 1 proof-of-concept study evaluating safety, tolerability, and biological marker responses with combination therapy of CTLA4-Ig and interleukin-2 in amyotrophic lateral sclerosis

D. Beers, Weihua Zhao, Jinghong Wang, 2024, Frontiers in neurology.