B. Cerra

发表

Flow nanoprecipitation of size-controlled d-leucine nanoparticles for spray-drying formulations

G. Mosca, M. Ricci, A. Gioiello, 2019, Reaction Chemistry & Engineering.

Beyond bile acids: targeting Farnesoid X Receptor (FXR) with natural and synthetic ligands.

R. Pellicciari, A. Macchiarulo, A. Gioiello, 2014, Current topics in medicinal chemistry.

BF3·Et2O-Promoted Decomposition of Cyclic α-Diazo-β-Hydroxy Ketones: Novel Insights into Mechanistic Aspects

R. Pellicciari, E. Camaioni, F. Venturoni, 2018, Catalysts.

Optimisation by Design of Experiment of Benzimidazol-2-One Synthesis under Flow Conditions

E. Banoglu, B. Cerra, Tuğçe Gür Maz, 2019, Molecules.

Binding Mode and Structure–Activity Relationships of ITE as an Aryl Hydrocarbon Receptor (AhR) Agonist

F. Quintana, P. Puccetti, G. Servillo, 2018, ChemMedChem.

Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor

A. De Luca, M. Redinbo, S. Mani, 2019, Journal of medicinal chemistry.

Synthesis of atypical bile acids for use as investigative tools for the genetic defect of 3β-hydroxy-Δ5-C27-steroid oxidoreductase deficiency

K. Setchell, G. Costantino, R. Pellicciari, 2014, The Journal of Steroid Biochemistry and Molecular Biology.

Selected cholesterol biosynthesis inhibitors produce accumulation of the intermediate FF-MAS that targets nucleus and activates LXRα in HepG2 cells.

L. Macchioni, R. Roberti, A. Gioiello, 2017, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Identification and quantification of oxo-bile acids in human faeces with liquid chromatography-mass spectrometry: A potent tool for human gut acidic sterolbiome studies.

J. Fiori, P. Simoni, E. Porru, 2019, Journal of chromatography. A.

Combining molecular modeling approaches to establish the chromatographic enantiomer elution order in the absence of pure enantiomeric standards: A study case with two tetracyclic quinolines

A. Gioiello, A. Carotti, R. Sardella, 2022, SEPARATION SCIENCE PLUS.

Development of 3α,7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-sulfate sodium salt (INT-767): Process optimization, synthesis and characterization of metabolites.

Anna Maria Lozza, I. Baxendale, R. Pellicciari, 2022, European journal of medicinal chemistry.

Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms

C. Supuran, A. Gioiello, A. Nocentini, 2018, Journal of enzyme inhibition and medicinal chemistry.

Selective continuous flow synthesis of hydroxy lactones from alkenoic acids

Anna Maria Lozza, A. Gioiello, B. Cerra, 2017 .

Integrating experimental and computational techniques to study chromatographic enantioresolutions of chiral tetrahydroindazole derivatives.

A. Gioiello, R. Galarini, G. Saluti, 2020, Journal of chromatography. A.

A streamlined synthesis of the neurosteroid 3β-methoxypregnenolone assisted by a statistical experimental design and automation

Antimo Gioiello, Valentina Mancino, Bruno Cerra, 2020 .

Enantioselective HPLC Analysis to Assist the Chemical Exploration of Chiral Imidazolines

A. Macchiarulo, E. Camaioni, A. Gioiello, 2020, Molecules.

First Total Synthesis of Piperenol B and Configuration Revision of the Enantiomers Piperenol B and Uvarirufol A

Michael J. Fink, M. Mihovilovic, Florian Rudroff, 2015 .

9. The Systems Biology of Transporters – Targeting the Regulatory System for Transporters (FXR/RXR)

R. Pellicciari, A. Macchiarulo, A. Gioiello, 2017 .

Continuous Flow Synthesis of 16-Dehydropregnenolone Acetate, a Key Synthon for Natural Steroids and Drugs

A. Gioiello, B. Cerra, A. Piccinno, 2018 .

Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification.

R. Pellicciari, A. Macchiarulo, A. Gioiello, 2018, European journal of medicinal chemistry.

The Medicinal Chemistry in the Era of Machines and Automation: Recent Advances in Continuous Flow Technology

Anna Maria Lozza, A. Gioiello, B. Cerra, 2020, Journal of medicinal chemistry.

Turning a Tumor Microenvironment Pitfall into Opportunity: Discovery of Benzamidoxime as PD-L1 Ligand with pH-Dependent Potency

E. Puxeddu, S. Moretti, A. Macchiarulo, 2023, International journal of molecular sciences.

The Stone Guest: How Does pH Affect Binding Properties of PD‐1/PD‐L1 Inhibitors?

E. Puxeddu, S. Moretti, A. Mammoli, 2020, ChemMedChem.

Concepts and Optimization Strategies of Experimental Design in Continuous-Flow Processing

Antimo Gioiello, Valentina Mancino, Paolo Filipponi, 2016, Journal of Flow Chemistry.

Bile acid derivatives as ligands of the farnesoid x receptor: molecular determinants for bile acid binding and receptor modulation.

R. Pellicciari, A. Macchiarulo, A. Gioiello, 2014, Current topics in medicinal chemistry.

Integrating multicomponent flow synthesis and computational approaches for the generation of a tetrahydroquinoline compound based library

A. Macchiarulo, A. Gioiello, B. Cerra, 2016 .

Exploiting Chemical Toolboxes for the Expedited Generation of Tetracyclic Quinolines as a Novel Class of PXR Agonists.

Roccaldo Sardella, Andrea Carotti, Antonio Macchiarulo, 2018, ACS medicinal chemistry letters.

Merging Continuous Flow Technology, Photochemistry and Biocatalysis to Streamline Steroid Synthesis

A. Gioiello, B. Cerra, F. Mutti, 2023, Advanced Synthesis & Catalysis.

Chemical exploration of TGR5 functional hot-spots: Synthesis and structure-activity relationships of C7- and C23-Substituted cholic acid derivatives.

R. Pellicciari, A. Gioiello, A. Carotti, 2023, European journal of medicinal chemistry.

Patented farnesoid X receptor modulators: a review (2019 - present).

A. Gioiello, Emiliano Rosatelli, B. Cerra, 2024, Expert Opinion on Therapeutic Patents.