J. Hawkins

发表

Process Development of CuI/ABNO/NMI-Catalyzed Aerobic Alcohol Oxidation

Christopher J. Welch, Joel M. Hawkins, Joseph R. Martinelli, 2015 .

Experimental Limiting Oxygen Concentrations for Nine Organic Solvents at Temperatures and Pressures Relevant to Aerobic Oxidations in the Pharmaceutical Industry

Christopher J. Welch, Joel M. Hawkins, Joseph R. Martinelli, 2014, Organic process research & development.

Osmylation of C60: proof and characterization of the soccer-ball framework

J. Hawkins, 1992 .

Flow Heck reactions using extremely low loadings of phosphine-free palladium acetate.

Joel M Hawkins, K. E. Price, Patrick Cyr, 2013, Organic letters.

Flow Heck Reactions Using Extremely Low Loadings of Phosphine-Free Palladium Acetate.

K. E. Price, J. Hawkins, P. Cyr, 2014 .

Evaluation of Kilogram-Scale Sonagashira, Suzuki, and Heck Coupling Routes to Oncology Candidate CP-724,714

Barbara J. Sitter, J. E. Phillips, D. Ripin, 2005 .

Crystal Structure of Osmylated C60: Confirmation of the Soccer Ball Framework

T. Lewis, F. Hollander, J M Hawkins, 1991, Science.

Optically Active Carbon: Kinetic Resolution of C76 by Asymmetric Osmylation

J. Hawkins, A. Meyer, 1993, Science.

Crystal Structure of Osmylated C60: Confirmation of the Soccer Ball Framework

T. Lewis, F. Hollander, J. Hawkins, 1991, Science.

The Open Reaction Database.

Connor W. Coley, Michael R. Maser, Michael R Maser, 2021, Journal of the American Chemical Society.

Reduction of Aromatic Disulfides with Triphenylphosphine.

R. E. Humphrey, J. Hawkins, 1964 .

Regiochemistry of the bisosmylation of fullerene C60: ortho, meta, and para in three dimensions

T. Ebbesen, T. Lewis, U. Bunz, 1992 .

Resolution and Configurational Stability of the Chiral Fullerenes C76, C78, and C84: A Limit for the Activation Energy of the Stone-Wales Transformation

M. Nambu, J. Hawkins, A. Meyer, 1994 .

Osmylation of C70: reactivity versus local curvature of the fullerene spheroid

J. Hawkins, A. Meyer, Michael Solow, 1993 .

A crystallographic analysis of C60(Buckminsterfullerene)

J. Heath, T. Lewis, R. Saykally, 1991 .

Asymmetric bisosmylation of fullerene C60: novel chiral .pi.-systems

M. Nambu, J. Hawkins, A. Meyer, 1993 .

Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13.

J. Barberia, T. Carty, J. Liras, 2005, Bioorganic & medicinal chemistry letters.

2D nuclear magnetic resonance analysis of osmylated C60

J. Hawkins, A. Meyer, S. Loren, 1991 .

Efficient, continuous N-Boc deprotection of amines using solid acid catalysts

Bryan M. Li, S. Scott, Jing Wu, 2021, Reaction Chemistry & Engineering.

Continuous Process for Preparing the Difluoromethylating Reagent [(DMPU)2Zn(CF2H)2] and Improved Synthesis of the ICHF2 Precursor

Adam R. C. Brown, Yuan-Qing Fang, J. Hawkins, 2020 .

Asymmetric Michael reactions of 3,5-dihydro-4H-dinaphth[2,1-c:1',2'-e]azepine with methyl crotonate

G. C. Fu, J. Hawkins, 1986 .

Mild and selective heterogeneous catalytic hydration of nitriles to amides by flowing through manganese dioxide.

S. Ley, C. Battilocchio, J. Hawkins, 2014, Organic letters.

Alkene isomerizations with boron trichloride-hydrogen chloride solutions

J. Hawkins, Young-Kyoon Kim, S. Loren, 1991 .

A Versatile Room-Temperature Route to Di- and Trisubstituted Allenes Using Flow-Generated Diazo Compounds**

Claudio Battilocchio, Joel M Hawkins, Steven V Ley, 2015, Angewandte Chemie.

Flow chemistry as a discovery tool to access sp2–sp3 cross-coupling reactions via diazo compounds† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c4sc03072a Click here for additional data file.

Claudio Battilocchio, Steven V. Ley, Joel M. Hawkins, 2014, Chemical science.

Process Intensification for the Continuous Flow Hydrogenation of Ethyl Nicotinate

Claudio Battilocchio, Steven V. Ley, Joel M. Hawkins, 2014 .

Asymmetric epoxidation models: An alkyl hydroperoxide dependent change in mehanism

J. Hawkins, K. B. Sharpless, 1987 .

Mild and selective heterogeneous catalytic hydration of nitriles to amides by flowing through manganese dioxide.

Claudio Battilocchio, Joel M Hawkins, Steven V Ley, 2014, Organic Letters.

Continuous Flow Hydration of Pyrazine-2-carbonitrile in a Manganese Dioxide Column Reactor

S. Ley, C. Battilocchio, J. Hawkins, 2017, Organic Syntheses.

Sustainable flow Oppenauer oxidation of secondary benzylic alcohols with a heterogeneous zirconia catalyst.

Claudio Battilocchio, Joel M Hawkins, Steven V Ley, 2013, Organic letters.

A mild and efficient flow procedure for the transfer hydrogenation of ketones and aldehydes using hydrous zirconia.

S. Ley, C. Battilocchio, J. Hawkins, 2013, Organic letters.

Directed Ortho Metalation of Neopentyl Benzoates with LDA: Preparation of Arylboronic Acids

S. Caron, J. Hawkins, 1998 .

DBU catalysis of N,N'-carbonyldiimidazole-mediated amidations.

Brian P. Jones, K. E. Price, J. Hawkins, 2010, Organic letters.

Mild and efficient DBU-catalyzed amidation of cyanoacetates.

Jason Mustakis, Joel M Hawkins, Rajappa Vaidyanathan, 2009, Organic letters.

Synthesis of trovafloxacin using various (1α,5α,6α)-3-azabicyclo[3.1.0]hexane derivatives

T. Norris, J. Hawkins, M. Butters, 2000 .

Asymmetric Lewis Acid-Dienophile Complexation: Secondary Attraction versus Catalyst Polarizability

M. Nambu, J. Hawkins, S. Loren, 1994 .

Flow‐Based, Cerium Oxide Enhanced, Low‐Level Palladium Sonogashira and Heck Coupling Reactions by Perovskite Catalysts

S. Ley, C. Battilocchio, Benjamin J. Deadman, 2014 .

Synthesis of an H3 Antagonist via Sequential One-Pot Additions of a Magnesium Ate Complex and an Amine to a 1,4-Ketoester followed by Carbonyl-Directed Fluoride Addition

S. M. Chesnut, J. Hawkins, R. Vaidyanathan, 2012 .

Asymmetric catalysis in the pharmaceutical industry.

J. Hawkins, T. Watson, 2004, Angewandte Chemie.

An asymmetric ammonia synthon for Michael additions

T. Lewis, J. Hawkins, 1992 .

Asymmetric synthesis of erythro and threo .alpha.-substituted .beta.-amino esters

T. Lewis, J. Hawkins, 1994 .

Streamlined Processes for the Synthesis of a Farnesyl Transferase Inhibitor Drug Candidate

J. Lyssikatos, M. D’Occhio, J. Hawkins, 2004 .

A Systems Approach towards an Intelligent and Self-Controlling Platform for Integrated Continuous Reaction Sequences**

Richard J Ingham, Claudio Battilocchio, Joel M Hawkins, 2014, Angewandte Chemie.

Cyclopropanation using flow-generated diazo compounds.

Richard J Ingham, Claudio Battilocchio, Joel M Hawkins, 2015, Organic & biomolecular chemistry.

Threo-N,N'-Bis(.alpha.-methylbenzyl)sulfamide: a readily available chiral ligand for asymmetric lithium aluminum hydride reductions

J. Hawkins, K. B. Sharpless, 1984 .

Two-point-binding asymmetric Diels-Alder catalysts : aromatic alkyldichloroboranes

J. Hawkins, S. Loren, 1991 .

Alkene Isomerizations with Boron Trifluoride-Hydrogen Chloride Solutions.

J. Hawkins, Young-Kyoon Kim, S. Loren, 2010 .

A mild and efficient flow procedure for the transfer hydrogenation of ketones and aldehydes using hydrous zirconia.

Claudio Battilocchio, Joel M Hawkins, Steven V Ley, 2013, Organic letters.

Asymmetric Lewis Acid-Catalyzed Diels−Alder Reactions of α,β-Unsaturated Ketones and α,β-Unsaturated Acid Chlorides

M. Nambu, J. Hawkins, S. Loren, 2003 .

Force-field modeling of the stereoselective Michael additions of an optically active amine and its lithium amide to acrylates

K. Houk, R. Loncharich, J. Hawkins, 1988 .

Process Research and Scale-up of the κ-Opioid Receptor Agonist CJ-15,161 Drug Candidate

Nga M. Do, Arun K. Ghosh, S. Caron, 2006 .

Electrochemical oxidation coupled with liquid chromatography and mass spectrometry to study the oxidative stability of active pharmaceutical ingredients in solution: A comparison of off-line and on-line approaches.

R. Szucs, J. Hawkins, Todd Zelesky, 2016, Journal of pharmaceutical and biomedical analysis.

Substituent effects on sulfonate ester based olefinations

T. Lewis, A. Raw, J. Hawkins, 1990 .

Organic chemistry of C60 (Buckminsterfullerene): chromatography and osmylation.

J. Heath, T. Lewis, R. Saykally, 1991, The Journal of organic chemistry.

Rapid Synthesis of Pharmaceutical Oxidation Products Using Electrochemistry: A Systematic Study of N-Dealkylation Reactions of Fesoterodine Using a Commercially Available Synthesis Cell

R. Szucs, A. Pettman, J. Hawkins, 2015 .

Systematic Optimization of Liquid–Liquid Extraction for Isolation of Unidentified Components

Ivo Leito, Koji Muteki, Joel M. Hawkins, 2017, ACS omega.

Continuous Processing in the Pharmaceutical Industry

Joel M. Hawkins, Peter J. Dunn, A. Wells, 2010 .

Stoichiometry identification of pharmaceutical reactions using the constrained dynamic response surface methodology

Shane T. Grosser, C. Georgakis, J. McMullen, 2019, AIChE Journal.

The application of electrochemistry to pharmaceutical stability testing--comparison with in silico prediction and chemical forced degradation approaches.

R. Szucs, A. Pettman, J. Hawkins, 2015, Journal of Pharmaceutical and Biomedical Analysis.

Constrained Version of the Dynamic Response Surface Methodology for Modeling Pharmaceutical Reactions

Yachao Dong, Christos Georgakis, Jason Mustakis, 2019, Industrial & Engineering Chemistry Research.

Statistical incorporation of carbon-13 13C2 units into C60 (buckminsterfullerene)

J. Hawkins, A. Meyer, S. Loren, 1991 .

Integration of enabling methods for the automated flow preparation of piperazine-2-carboxamide

Richard J Ingham, Claudio Battilocchio, Joel M Hawkins, 2014, Beilstein journal of organic chemistry.

Flow‐Based, Cerium Oxide Enhanced, Low‐Level Palladium Sonogashira and Heck Coupling Reactions by Perovskite Catalysts.

S. Ley, C. Battilocchio, Benjamin J. Deadman, 2014 .

One-Pot, Metal- and Azide-Free Synthesis of 1,2,3-Triazoles from α-Ketoacetals and Amines

S. Sutton, J. Hawkins, L. Zehnder, 2019, Synlett.

Precompetitive Collaboration on Enabling Technologies for the Pharmaceutical Industry

Christopher J. Welch, Joel M. Hawkins, Jean W. Tom, 2014 .

Organic chemistry: Streamlining drug synthesis

Joel M. Hawkins, J. Hawkins, 2015, Nature.

Mild and Efficient DBU‐Catalyzed Amidation of Cyanoacetates.

K. E. Price, Jason Mustakis, J. Hawkins, 2009 .

A Crystallographic Analysis of C60 (Buckminsterfullerene).

J. Heath, T. Lewis, R. Saykally, 1992 .