Liren Wang

发表

CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos

Dali Li, Ming-Yu Liu, Dali Li, 2014, Nature Protocols.

Amelioration of hemophilia B through CRISPR/Cas9 induced homology-independent targeted integration

Mingyao Liu, Dali Li, Jiazhi Hu, 2021 .

Amelioration of hemophilia B through CRISPR/Cas9 induced homology-independent targeted integration

Ming-Yu Liu, Mingyao Liu, Dali Li, 2021, bioRxiv.

Amelioration of an Inherited Metabolic Liver Disease through Creation of a De Novo Start Codon by Cytidine Base Editing.

Ming-Yu Liu, Mingyao Liu, Dali Li, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

Increasing the efficiency and targeting range of cytidine base editors through fusion of a single-stranded DNA-binding protein domain

Ming-Yu Liu, Mingyao Liu, Dali Li, 2020, Nature Cell Biology.

GATA zinc finger domain‐containing protein 2A (GATAD2A) deficiency reactivates fetal haemoglobin in patients with β‐thalassaemia through impaired formation of methyl‐binding domain protein 2 (MBD2)‐containing nucleosome remodelling and deacetylation (NuRD) complex

Dali Li, Yukio Nakamura, R. Kurita, 2021, British journal of haematology.

Long-term correction of haemophilia B through CRISPR/Cas9 induced homology-independent targeted integration.

Ming-Yu Liu, Dali Li, Jiazhi Hu, 2022, Journal of genetics and genomics = Yi chuan xue bao.

A natural DNMT1 mutation elevates the fetal hemoglobin via epigenetic de-repression of γ-globin gene in β-thalassemia.

Tizhen Yan, Wenxia Yu, Yuhua Ye, 2020, Blood.

Long-term amelioration of an early-onset familial atrial fibrillation model with AAV-mediated in vivo gene therapy

Dali Li, Mingyao Liu, W. Peng, 2022, Fundamental Research.

Stable Transgenic Mouse Strain with Enhanced Photoactivatable Cre Recombinase for Spatiotemporal Genome Manipulation

Ming-Yu Liu, L. Hui, Longnian Lin, 2022, Advanced science.

Dual base editor catalyzes both cytosine and adenine base conversions in human cells

Mingyao Liu, Xiufeng Pang, Dali Li, 2020, Nature Biotechnology.

CRISPR–Cas9-mediated gene editing of the BCL11A enhancer for pediatric β0/β0 transfusion-dependent β-thalassemia

Ming-Yu Liu, Dali Li, Fangping Chen, 2022, Nature Medicine.

Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Ming-Yu Liu, Dali Li, C. Yi, 2022, Nature Biotechnology.

CRISPR/Cas9‐mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse

Mingyao Liu, Dali Li, Qi Li, 2016, EMBO molecular medicine.

Knockdown of lactate dehydrogenase by adeno‐associated virus‐delivered CRISPR/Cas9 system alleviates primary hyperoxaluria type 1

Dali Li, Liren Wang, Xi Chen, 2020, Clinical and translational medicine.

CRISPR/Cas9-mediated metabolic pathway reprogramming in a novel humanized rat model ameliorates primary hyperoxaluria type 1.

Dali Li, Liren Wang, Rui Zheng, 2020, Kidney international.

Characterization of novel cytochrome P450 2E1 knockout rat model generated by CRISPR/Cas9.

Mingyao Liu, Dali Li, Yanjiao Shao, 2016, Biochemical pharmacology.

Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice

M. Surette, S. Ng, C. Klein, 2021, Nature Genetics.

Gene editing and its applications in biomedicine

Jin Wang, Haoyi Wang, Wensheng Wei, 2022, Science China Life Sciences.

PAK1IP1, a ribosomal stress-induced nucleolar protein, regulates cell proliferation via the p53–MDM2 loop

Z. Yi, Dali Li, Jian Luo, 2010, Nucleic acids research.

Large genomic fragment deletion and functional gene cassette knock-in via Cas9 protein mediated genome editing in one-cell rodent embryos

Liang Li, Yanlin Ma, Dali Li, 2015, Scientific Reports.

Heritable gene targeting in the mouse and rat using a CRISPR-Cas system

Yongxiang Zhao, Dali Li, Ming-Yu Liu, 2013, Nature Biotechnology.

Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia.

Dali Li, Yafeng Li, Yukio Nakamura, 2021, American Journal of Human Genetics.

CRISPR/Cas9 system: a powerful technology for in vivo and ex vivo gene therapy

Ming-Yu Liu, Mingyao Liu, Dali Li, 2017, Science China Life Sciences.

Enhanced genome editing to ameliorate a genetic metabolic liver disease through co-delivery of adeno-associated virus receptor

Mingyao Liu, Dali Li, N. Shen, 2020, Science China Life Sciences.

Cas9-nickase–mediated genome editing corrects hereditary tyrosinemia in rats

L. Hui, Mingyao Liu, Dali Li, 2018, The Journal of Biological Chemistry.

Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouse

Longnian Lin, Mingyao Liu, Dali Li, 2020, Proceedings of the National Academy of Sciences.

Correction to: Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants

Mingyao Liu, Dali Li, Liren Wang, 2018, Protein & Cell.

Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants

Ming-Yu Liu, Liren Wang, Rui Zheng, 2018, Protein & Cell.

Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants

Mingyao Liu, Dali Li, Liren Wang, 2018, Protein & Cell.

Feedback activation of EGFR/wild-type RAS signaling axis limits KRASG12D inhibitor efficacy in KRASG12D-mutated colorectal cancer

Xiufeng Pang, Cun-Yu Wang, Liren Wang, 2023, Oncogene.

Increasing the efficiency and targeting range of cytidine base editors through fusion of a single-stranded DNA-binding protein domain

Ming-Yu Liu, Dali Li, Weishi Yu, 2020, Nature Cell Biology.

Engineering a precise adenine base editor with minimal bystander editing

Ming-Yu Liu, Dali Li, C. Yi, 2022, Nature Chemical Biology.

Structure and function of Norrin in assembly and activation of a Frizzled 4–Lrp5/6 complex

Chen Chen, L. Miller, H. Xu, 2013, Genes & development.

Engineering precise adenine base editor with infinitesimal rates of bystander mutations and off-target editing

Ming-Yu Liu, Dali Li, C. Yi, 2022, bioRxiv.

Improving adenine and dual base editors through introduction of TadA-8e and Rad51DBD

Ming-Yu Liu, P. Zhu, Liren Wang, 2023, Nature Communications.

Modulation of β-Catenin Signaling by Glucagon Receptor Activation

L. Miller, H. Xu, B. Williams, 2012, PloS one.

Structure and function of Norrin in assembly and activation of a Frizzled 4 – Lrp 5 / 6 complex

L. Miller, H. Xu, B. Williams, 2013 .

Reactivation of γ-globin expression through Cas9 or base editor to treat β-hemoglobinopathies

Mingyao Liu, Dali Li, Yukio Nakamura, 2020, Cell Research.

Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryos.

Alexander A. Sousa, Ming-Yu Liu, Bo Feng, 2023, Nature biotechnology.

Engineering IscB to develop highly efficient miniature editing tools in mammalian cells and embryos

Yuting Guan, Liren Wang, Xi Chen, 2024, Molecular Cell.

Engineering APOBEC3A deaminase for highly accurate and efficient base editing.

C. Yi, Haowei Meng, Yuting Guan, 2024, Nature chemical biology.

Efficient expansion and CRISPR-Cas9-mediated gene correction of patient-derived hepatocytes for treatment of inherited liver diseases.

Jin Cen, Liren Wang, X. Yuan, 2024, Cell stem cell.