A. Koch

发表

Endocrine Dysfunction After Brain Tumor Therapy in Children

H. Dörr, A. Koch, T. Sauerwald, 1995 .

TNFα-induced GM-CSF release from human airway smooth muscle cells depends on activation of an ET-1 autoregulatory positive feedback mechanism

J. Knobloch, J. Strauch, A. Koch, 2009, Thorax.

Impaired TNFα-induced VEGF Expression in Human Airway Smooth Muscle Cells from Smokers with COPD: Role of MAPkinases and Histone Acetylation—Effect of Dexamethasone

P. Schneider, M. Raidl, J. Strauch, 2007, Cell Biochemistry and Biophysics.

Management of patients with idiopathic pulmonary fibrosis in clinical practice: the INSIGHTS-IPF registry

T. Welte, F. Herth, M. Kreuter, 2015, European Respiratory Journal.

Sex-specific associations of comorbidome and pulmorbidome with mortality in chronic obstructive pulmonary disease: results from COSYCONET

C. Kropf-Sanchen, H. Kauczor, H. Watz, 2022, Scientific reports.

&bgr;‐Blockers in COPD: A Cohort Study From the TONADO Research Program

F. Maltais, U. Bothner, R. Buhl, 2018, Chest.

Effect of lipoteichoic acid on IL-2 and IL-5 release from T lymphocytes in asthma and COPD.

J. Knobloch, A. Koch, Zeynep Mat, 2012, International immunopharmacology.

IL-5 release of CD4+ non-effector lymphocytes is increased in COPD--modulating effects of moxifloxacin and dexamethasone.

J. Knobloch, A. Koch, D. Jungck, 2011, International immunopharmacology.

Quantitative Secretome Analysis of Activated Jurkat Cells Using Click Chemistry-Based Enrichment of Secreted Glycoproteins.

B. Sitek, D. A. Megger, M. Eisenacher, 2017, Journal of proteome research.

Direct and indirect costs of COPD and its comorbidities: Results from the German COSYCONET study.

R. Holle, A. Peters, J. Heinrich, 2016, Respiratory medicine.

One-Year Safety of Olodaterol Once Daily via Respimat® in Patients with GOLD 2–4 Chronic Obstructive Pulmonary Disease: Results of a Pre-Specified Pooled Analysis

D. Niewoehner, C. Vogelmeier, U. Bothner, 2015, COPD.

Lung function efficacy and symptomatic benefit of olodaterol once daily delivered via Respimat® versus placebo and formoterol twice daily in patients with GOLD 2–4 COPD: results from two replicate 48-week studies

E. Pizzichini, P. Paggiaro, M. De Salvo, 2014, International journal of chronic obstructive pulmonary disease.

Cyclooxygenase‐2 expression in lung cancer cells evaluated by immunocytochemistry

H. Fohlin, B. Gustafsson, A. Koch, 2010, Diagnostic cytopathology.

TLR3 and TLR4 expression in healthy and diseased human endometrium

R. Kimmig, I. Gashaw, A. Koch, 2008, Reproductive biology and endocrinology : RB&E.

Sex-specific associations of comorbidome and pulmorbidome with mortality in chronic obstructive pulmonary disease: results from COSYCONET

C. Kropf-Sanchen, H. Kauczor, H. Watz, 2022, Scientific reports.

P230 Symptomatic benefit of olodaterol QD delivered via Respimat® vs placebo and formoterol BID in patients with COPD: combined analysis from two 48-week studies

E. Pizzichini, P. Paggiaro, M. De Salvo, 2013, Thorax.

Lung function efficacy of olodaterol QD delivered via Respimat® vs placebo and formoterol BID in patients with COPD: Two 48-week studies

E. Pizzichini, P. Paggiaro, A. Koch, 2013 .

The T-helper cell type 1 immune response to gram-negative bacterial infections is impaired in COPD.

J. Knobloch, J. Rupp, E. Schweda, 2011, American journal of respiratory and critical care medicine.

Resveratrol Impairs the Release of Steroid-Resistant Inflammatory Cytokines from Human Airway Smooth Muscle Cells in Chronic Obstructive Pulmonary Disease

E. Stoelben, J. Knobloch, J. Strauch, 2010, Journal of Pharmacology and Experimental Therapeutics.

Comprehensive assessment of the safety of olodaterol 5 µg in the Respimat® device for maintenance treatment of COPD: comparison with the long-acting β2-agonist formoterol

H. Watz, M. R. Maleki-Yazdi, U. Bothner, 2017, npj Primary Care Respiratory Medicine.

TNFα-induced airway smooth muscle cell proliferation depends on endothelin receptor signaling, GM-CSF and IL-6.

E. Stoelben, J. Knobloch, A. Koch, 2016, Biochemical pharmacology.

LABAs and p38MAPK Inhibitors Reverse the Corticosteroid-Insensitivity of IL-8 in Airway Smooth Muscle Cells of COPD

E. Stoelben, J. Knobloch, Kazuhiro Ito, 2019, Journal of clinical medicine.

Superior anti‐inflammatory effects of narrow‐spectrum kinase inhibitors in airway smooth muscle cells from subjects with chronic obstructive pulmonary disease

E. Stoelben, J. Knobloch, C. Charron, 2017, The Journal of allergy and clinical immunology.

Mitogen-activated protein kinase modulation of nuclear factor-kappaB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages.

I. Adcock, K. Chung, P. Barnes, 2004, American journal of respiratory cell and molecular biology.

A Systemic Defect in Toll-like Receptor 4 Signaling Increases 1 Lipopolysaccharide-induced Suppression of Il-2-dependent T-cell Proliferation in Copd 2 3 Running Head: Defective Il-2 Dependent Infection Defense in Copd 17

J. Knobloch, J. Rupp, A. Koch, 2022 .

Resveratrol Attenuates the Release of Inflammatory Cytokines from Human Bronchial Smooth Muscle Cells Exposed to Lipoteichoic Acid in Chronic Obstructive Pulmonary Disease

E. Stoelben, J. Knobloch, M. Feldmann, 2014, Basic & clinical pharmacology & toxicology.

Exposure to welding fumes suppresses the activity of T-helper cells.

T. Brüning, J. Knobloch, J. Rupp, 2020, Environmental research.

Resveratrol impairs the release of steroid-resistant cytokines from bacterial endotoxin-exposed alveolar macrophages in chronic obstructive pulmonary disease.

J. Knobloch, A. Koch, D. Jungck, 2011, Basic & clinical pharmacology & toxicology.

Biomarkers for Comorbidities Modulate the Activity of T-Cells in COPD

J. Knobloch, A. Koch, D. Jungck, 2021, International journal of molecular sciences.

Real‐life effectiveness of biological therapies on symptoms in severe asthma with comorbid CRSwNP

M. Gröger, M. Canis, J. Behr, 2021, Clinical and translational allergy.

Inflammatory responses of airway smooth muscle cells and effects of endothelin receptor antagonism.

J. Behr, E. Stoelben, J. Knobloch, 2013, American journal of respiratory cell and molecular biology.

Effect of smoking on MAP kinase-induced modulation of IL‐8 in human alveolar macrophages

I. Adcock, S. Lim, M. Giembycz, 2004, European Respiratory Journal.

Olfactory Receptors Modulate Physiological Processes in Human Airway Smooth Muscle Cells

E. Stoelben, S. Philippou, J. Knobloch, 2016, Front. Physiol..

Activation of immune cell proteasomes in peripheral blood of smokers and COPD patients: implications for therapy

H. Schulz, Yuqin Wang, S. Hauck, 2021, European Respiratory Journal.

Reproductive Biology and Endocrinology Open Access Tlr3 and Tlr4 Expression in Healthy and Diseased Human Endometrium

R. Kimmig, I. Gashaw, A. Koch, 2008 .

Regulation of matrix metalloproteinases and their inhibitors in uterine endometrial cells of patients with and without endometriosis.

M. Neher, S. Prifti, B. Runnebaum, 2001, European journal of obstetrics, gynecology, and reproductive biology.

Effect of celecoxib on survival in patients with advanced non-small cell lung cancer: a double blind randomised clinical phase III trial (CYCLUS study) by the Swedish Lung Cancer Study Group.

Bengt Bergman, Erik Holmberg, Lars Thaning, 2011, European journal of cancer.

Clinical Aspects of Inflammation in Non-small Cell Lung Cancer

A. Koch, 2011 .

Apoptosis induction by thalidomide: critical for limb teratogenicity but therapeutic potential in idiopathic pulmonary fibrosis?

J. Knobloch, A. Koch, D. Jungck, 2011, Current molecular pharmacology.

Distinguishing synchronous from metachronous manifestation of distant metastases: a prognostic feature in differentiated thyroid carcinoma

H. Biersack, I. Binse, S. Ezziddin, 2017, European Journal of Nuclear Medicine and Molecular Imaging.

IL-12-induced T-bet expression and IFNgamma release in lymphocytes from asthmatics--role of MAPkinases ERK-1/-2, p38(MAPK) and effect of dexamethasone.

H. Büning, Sibille Humme, M. Raidl, 2007, Respiratory medicine.

Asthma features in severe COPD: Identifying treatable traits.

Jürgen Behr, Sandhya Matthes, C. Neurohr, 2018, Respiratory medicine.

Biomarkers in Lung Diseases : from Pathogenesis to Prediction to New Therapies A systemic defect in Toll-like receptor 4 signaling increases lipopolysaccharide-induced suppression of IL-2-dependent T-cell proliferation in COPD

J. Knobloch, J. Rupp, A. Koch, 2015 .

Endothelin Receptor B Protects Granulocyte Macrophage Colony-Stimulating Factor mRNA from Degradation

E. Stoelben, J. Knobloch, A. Koch, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Running Title : Endothelin Receptor B Protects GM-CSF mRNA from Degradation

E. Stoelben, J. Knobloch, A. Koch, 2015 .

Endothelin Receptor Antagonists Attenuate the Inflammatory Response of Human Pulmonary Vascular Smooth Muscle Cells to Bacterial Endotoxin

E. Stoelben, J. Knobloch, M. Feldmann, 2013, The Journal of Pharmacology and Experimental Therapeutics.

Microsoft Word-5143-file00

E. Stoelben, J. Knobloch, M. Feldmann, 2013 .

β-Blockers in COPD

F. Maltais, U. Bothner, R. Buhl, 2018, Chest.

Pulmonary , gastrointestinal and urogenital pharmacology Simvastatin requires activation in accessory cells to modulate T-cell responses in asthma and COPD

J. Knobloch, A. Koch, D. Jungck, 2016 .

Fraction of exhaled nitric oxide is associated with disease burden in the German Asthma Net severe asthma cohort

M. Idzko, S. Zehetmayer, E. Hamelmann, 2022, European Respiratory Journal.

Prognostic Significance of C-Reactive Protein and Smoking in Patients with Advanced Non-small Cell Lung Cancer Treated with First-Line Palliative Chemotherapy

H. Fohlin, A. Koch, S. Sörenson, 2009, Journal of Thoracic Oncology.

The Molecular Mechanisms of Thalidomide Teratogenicity and Implications for Modern Medicine.

J. Knobloch, A. Koch, D. Jungck, 2017, Current molecular medicine.

Effect of bacterial endotoxin LPS on expression of INF-gamma and IL-5 in T-lymphocytes from asthmatics.

J. Knobloch, Cathrin Dammhayn, A. Ruppert, 2007, Clinical immunology.

The German severe asthma register

K. Bergmann, S. Korn, P. Kardos, 2012 .

Symptoms and quality of life in relation to lung function and comorbidities in patients with idiopathic pulmonary fibrosis: INSIGHTS-IPF registry

A. Prasse, J. Behr, M. Kreuter, 2016 .

Mitogen-activated protein kinase modulation of nuclear factor-kappaB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages.

I. Adcock, Kazuhiro Ito, Sam Lim, 2004, American journal of respiratory cell and molecular biology.

Serum BNP levels in COPD, asthma-COPD-overlap-syndrome, smokers and never-smokers

J. Knobloch, A. Koch, D. Jungck, 2016 .

CALL FOR PAPERS Biomarkers in Lung Diseases: from Pathogenesis to Prediction to New Therapies A systemic defect in Toll-like receptor 4 signaling increases lipopolysaccharide-induced suppression of IL-2-dependent T-cell proliferation in COPD

J. Rupp, J. Knobloch, A. Koch, 2016 .

A systemic defect in Toll-like receptor 4 signaling increases lipopolysaccharide-induced suppression of IL-2-dependent T-cell proliferation in COPD.

J. Knobloch, A. Koch, D. Jungck, 2016, American journal of physiology. Lung cellular and molecular physiology.

Quantitative Secretome Analysis of Activated Jurkat Cells Using Click Chemistry-Based Enrichment of Secreted Glycoproteins.

B. Sitek, D. A. Megger, M. Eisenacher, 2017, Journal of proteome research.

Simvastatin requires activation in accessory cells to modulate T-cell responses in asthma and COPD.

A. Koch, D. Jungck, Barbara Grensemann, 2016, European journal of pharmacology.

48-week administration of olodaterol QD via Respimat® vs placebo and formoterol BID in patients with COPD: Pooled safety analysis

L. Mcgarvey, K. Tetzlaff, G. Ferguson, 2013 .

The monocyte-dependent immune response to bacteria is suppressed in smoking-induced COPD

J. Knobloch, J. Rupp, A. Koch, 2019, Journal of Molecular Medicine.

Modification of surface antigens in blood CD8+ T-lymphocytes in COPD: effects of smoking

A. Rubbert, P. Staib, A. Koch, 2006, European Respiratory Journal.