E. Ehrenborg

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Plaque Evaluation by Ultrasound and Transcriptomics Reveals BCLAF1 as a Regulator of Smooth Muscle Cell Lipid Transdifferentiation in Atherosclerosis

P. Eriksson, J. Skogsberg, E. Treuter, 2022, Arteriosclerosis, thrombosis, and vascular biology.

Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia

M. Hayden, S. Young, A. Beigneux, 2010, Journal of Lipid Research.

Influence of common variants in the CETP, LPL, HL and APO E genes on LDL heterogeneity in healthy, middle-aged men.

A. Hamsten, F. Karpe, G. Olivecrona, 2003, Atherosclerosis.

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

M. Ridderstråle, L. Groop, M. Orho-Melander, 2009, Diabetologia.

Activation of peroxisome proliferator-activated receptor delta stimulates the proliferation of human breast and prostate cancer cell lines.

A. Harris, C. Wolf, D. Knight, 2004, Cancer research.

Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content

J. Zierath, A. Krook, A. Chibalin, 2003, Cellular and Molecular Life Sciences CMLS.

MicroRNA 486-3P as a stability marker in acute coronary syndrome

A. Gabrielsen, L. Folkersen, T. Wei, 2016, Bioscience reports.

Acquired obesity increases CD68 and tumor necrosis factor-alpha and decreases adiponectin gene expression in adipose tissue: a study in monozygotic twins.

A. Rissanen, A. Hamsten, K. Pietiläinen, 2006, The Journal of clinical endocrinology and metabolism.

A Case-Control Study of Risk Markers and Mortality in Takotsubo Stress Cardiomyopathy.

P. Tornvall, Hans Järnbert-Petterson, E. Ehrenborg, 2016, Journal of the American College of Cardiology.

Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans.

R. Kim, B. Ekblom, A. Kotronen, 2012, International journal of molecular medicine.

PPARalpha regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes.

U. Andersson, H. Hellmold, I. Cotgreave, 2008, Toxicology and applied pharmacology.

A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels.

A. Hamsten, P. Eriksson, F. Karpe, 1998, Arteriosclerosis, thrombosis, and vascular biology.

Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions.

M. Jagodic, U. Hedin, J. Pelisek, 2018, Molecular therapy : the journal of the American Society of Gene Therapy.

UvA-DARE ( Digital Academic Repository ) A single Ser 259 Arg mutation in the gene for lipoprotein lipase causes chylomicronemia in Moroccans of Berber ancestry

M. Hayden, J. Kastelein, L. Foubert, 1997 .

A single Ser259Arg mutation in the gene for lipoprotein lipase causes chylomicronemia in Moroccans of Berber ancestry

M. Hayden, J. Kastelein, L. Foubert, 1997, Human mutation.

Assessment of French patients with LPL deficiency for French Canadian mutations.

M. Hayden, L. Foubert, J. Girardet, 1997, Journal of medical genetics.

ACQUIRED OBESITY INCREASES CD68 AND TNF-α AND DECREASES ADIPONECTIN GENE EXPRESSION IN ADIPOSE TISSUE. A study in monozygotic twins.

A. Rissanen, A. Hamsten, K. Pietiläinen, 2006 .

Conservation of IGFBP structure during evolution: cloning of chicken insulin-like growth factor binding protein-5.

H. Luthman, D. Powell, S. Allander, 1995, Progress in growth factor research.

Regulation of Plasma PAI-1 Concentrations in HAART-Associated Lipodystrophy During Rosiglitazone Therapy

A. Hamsten, A. Silveira, P. Eriksson, 2003, Arteriosclerosis, thrombosis, and vascular biology.

Direct activation of glucose transport in primary human myotubes after activation of peroxisome proliferator-activated receptor delta.

P. Wretenberg, J. Skogsberg, J. Zierath, 2005, Diabetes.

PPARδ activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells

A. Hamsten, J. Skogsberg, B. Glinghammar, 2003 .

Evidence That Peroxisome Proliferator–Activated Receptor Delta Influences Cholesterol Metabolism in Men

A. Hamsten, P. Eriksson, J. Skogsberg, 2003, Arteriosclerosis, thrombosis, and vascular biology.

Genetic Variation in SULF2 Is Associated with Postprandial Clearance of Triglyceride-Rich Remnant Particles and Triglyceride Levels in Healthy Subjects

N. Lundbom, J. Borén, M. Orho-Melander, 2013, PloS one.

A PPAR response element regulates transcription of the gene for human adipose differentiation-related protein.

J. McLauchlan, P. Targett-Adams, E. Ehrenborg, 2005, Biochimica et biophysica acta.

Peroxisome proliferator-activated receptor delta and cardiovascular disease.

J. Skogsberg, E. Ehrenborg, 2013, Atherosclerosis.

Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed‐forward loop between LXR and autophagy

J. Borén, S. Humphries, A. Smit, 2019, Journal of internal medicine.

Relationship between lipoprotein lipase and high density lipoprotein cholesterol in mice: modulation by cholesteryl ester transfer protein and dietary status.

M. Hayden, G. Shen, L. Miao, 1997, Journal of lipid research.

Activation of Peroxisome Proliferator-Activated Receptor Stimulates the Proliferation of Human Breast and Prostate Cancer Cell Lines

A. Harris, C. Wolf, D. Knight, 2004 .

MicroRNA-9 regulates the expression of peroxisome proliferator-activated receptor δ in human monocytes during the inflammatory response

D. Grandér, M. Corcoran, R. Fisher, 2013, International journal of molecular medicine.

PPARδ in humans: genetic and pharmacological evidence for a significant metabolic function

F. Karpe, E. Ehrenborg, 2009, Current opinion in lipidology.

Efficient adenovirus-mediated ectopic gene expression of human lipoprotein lipase in human hepatic (HepG2) cells.

M. Hayden, P. Denéfle, D. Ginzinger, 1997, Human gene therapy.

Childhood‐onset chylomicronaemia with reduced plasma lipoprotein lipase activity and mass: identification of a novel GPIHBP1 mutation

G. Olivecrona, E. Ehrenborg, P. González-Sántos, 2011, Journal of internal medicine.

Characterization and chromosomal localization of the human insulin-like growth factor-binding protein 6 gene

C. Larsson, H. Luthman, S. Lagercrantz, 1999, Mammalian Genome.

Inactivation of lipoprotein lipase occurs on the surface of THP-1 macrophages where oligomers of angiopoietin-like protein 4 are formed.

T. Olivecrona, G. Olivecrona, E. Makoveichuk, 2012, Biochemical and biophysical research communications.

Upregulated Autophagy in Calcific Aortic Valve Stenosis Confers Protection of Valvular Interstitial Cells

A. Franco‐Cereceda, P. Eriksson, Oscar Persson, 2019, International journal of molecular sciences.

Effects of prolonged exercise on left ventricular mechanical synchrony in long-distance runners: importance of previous exposure to endurance races.

A. Sahlén, A. Manouras, F. Braunschweig, 2010, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

Allele-specific regulation of MTTP expression influences the risk of ischemic heart disease[S]

J. Borén, A. Hamsten, A. Franco‐Cereceda, 2010, Journal of Lipid Research.

Allele-specifi c regulation of MTTP expression infl uences the risk of ischemic heart disease

J. Borén, A. Hamsten, A. Franco‐Cereceda, 2010 .

Characterization of the human peroxisome proliferator activated receptor delta gene and its expression.

C. Larsson, A. Hamsten, J. Skogsberg, 2000, International Journal of Molecular Medicine.

The minor allele of the missense polymorphism Ser251Pro in perilipin 2 (PLIN2) disrupts an α‐helix, affects lipolysis, and is associated with reduced plasma triglyceride concentration in humans

J. Borén, F. Karpe, M. Neville, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

In the lipodystrophy associated with highly active antiretroviral therapy, pseudo-Cushing’s syndrome is associated with increased regeneration of cortisol by 11β-hydroxysteroid dehydrogenase type 1 in adipose tissue

A. Hamsten, B. Walker, E. Korsheninnikova, 2004, Diabetologia.

The human insulin-like growth factor-binding protein 4 gene maps to chromosome region 17q12-q21.1 and is close to the gene for hereditary breast-ovarian cancer.

H. Huynh, P. Tonin, G. Lenoir, 1993, Genomics.

Structure and chromosomal localization of human insulin-like growth factor-binding protein genes.

C. Larsson, H. Luthman, D. Powell, 1993, Growth regulation.

Multi-hormonal regulation of IGFBP-6 expression in human neuroblastoma cells.

E. Ehrenborg, D. Chambéry, B. de Gallé, 2000, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Common variants in genes encoding plasma lipid-transfer and lipolytic proteins are associated with increased LDL particle size

A. Hamsten, F. Karpe, G. Olivecrona, 2002 .

Differential expression of peroxisomal proliferator activated receptors alpha and delta in skeletal muscle in response to changes in diet and exercise.

A. Hamsten, J. Zierath, A. Chibalin, 2006, International journal of molecular medicine.

Deficiency in perilipin 5 reduces mitochondrial function and membrane depolarization in mouse hearts.

J. Borén, A. Kimmel, Y. Lee, 2017, The international journal of biochemistry & cell biology.

ATG16L1 Expression in Carotid Atherosclerotic Plaques Is Associated With Plaque Vulnerability

A. Franco‐Cereceda, P. Eriksson, P. Kovanen, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass index.

F. Karpe, C. Skoglund-Andersson, E. Ehrenborg, 2002, Journal of lipid research.

Two common functional polymorphisms in the promoter region of the coagulation factor VII gene determining plasma factor VII activity and mass concentration.

A. Hamsten, A. Silveira, P. Eriksson, 1999, Blood.

The Q/E27 polymorphism in the β2‐adrenoceptor gene is associated with increased body weight and dyslipoproteinaemia involving triglyceride‐rich lipoproteins

A. Hamsten, P. Eriksson, V. Large, 2000, Journal of internal medicine.

Expression of adipogenic transcription factors, peroxisome proliferator-activated receptor gamma co-activator 1, IL-6 and CD45 in subcutaneous adipose tissue in lipodystrophy associated with highly active antiretroviral therapy

A. Hamsten, K. Gertow, E. Korsheninnikova, 2003, AIDS.

Structure and localization of the human insulin-like growth factor-binding protein 2 gene.

C. Larsson, H. Luthman, K. Brøndum‐Nielsen, 1991, Biochemical and biophysical research communications.

Regulation of Skeletal Muscle Physiology and Metabolism by Peroxisome Proliferator-Activated Receptor δ

A. Krook, E. Ehrenborg, 2009, Pharmacological Reviews.

Localization of the human insulin-like growth-factor-binding protein 4 gene to chromosomal region 17q12–21.1

C. Larsson, H. Luthman, K. Brøndum‐Nielsen, 1992, Human Genetics.

Contiguous localization of the genes encoding human insulin-like growth factor binding proteins 1 (IGBP1) and 3 (IGBP3) on chromosome 7.

C. Larsson, H. Luthman, D. Powell, 1992, Genomics.

The gene for insulin-like growth factor-binding protein-1 is localized to human chromosomal region 7p14-p12.

L. Zech, H. Luthman, E. Ehrenborg, 1990, Genomics.

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM

Valentina Paloschi, Per Eriksson, Mattias Vesterlund, 2016, Arteriosclerosis, thrombosis, and vascular biology.

Melatonin receptor 1B gene associated with hyperglycemia in bipolar disorder

C. Östenson, H. Gu, D. Erlinge, 2016, Psychiatric genetics.

Promoter analysis of the murine squalene epoxidase gene. Identification of a 205 bp homing region regulated by both SREBP'S and NF-Y.

E. Ehrenborg, M. Gåfvels, C. Murphy, 2006, Biochimica et biophysica acta.

Alternative splicing of human peroxisome proliferator-activated receptor delta (PPARdelta):effects on translation efficiency and trans-activation ability

A. Hamsten, E. Ehrenborg, Petra Thulin, 2007, BMC Molecular Biology.

Characterization of the chromosomal gene and promoter for human insulin-like growth factor binding protein-5.

C. Larsson, H. Luthman, D. Powell, 1994, The Journal of biological chemistry.

Lack of genetic susceptibility in takotsubo cardiomyopathy: a case-control study

P. Tornvall, P. Saliba-Gustafsson, E. Ehrenborg, 2018, BMC Medical Genetics.

Differential expression of peroxisomal proliferator activated receptors α and δ in skeletal muscle in response to changes in diet and exercise

A. Hamsten, J. Zierath, A. Chibalin, 2006 .

Ethnic variation and in vivo effects of the -93t-->g promoter variant in the lipoprotein lipase gene.

M. Hayden, J. Ordovás, J. Kastelein, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Effects of rosiglitazone on gene expression in subcutaneous adipose tissue in highly active antiretroviral therapy-associated lipodystrophy.

T. Funahashi, Y. Matsuzawa, A. Hamsten, 2004, American journal of physiology. Endocrinology and metabolism.

Perilipin 5 is protective in the ischemic heart.

J. Borén, P. Eriksson, A. Kimmel, 2016, International journal of cardiology.

The Microsomal Triglyceride Transfer Protein Gene-493T Variant Lowers Cholesterol But Increases the Risk of Coronary Heart Disease

P. Macfarlane, F. Karpe, M. Neville, 2004, Circulation.

Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.

J. Borén, A. Mardinoğlu, A. Franco‐Cereceda, 2019, Journal of molecular and cellular cardiology.

The Ile128Thr polymorphism influences stability and ligand binding properties of the microsomal triglyceride transfer protein Published, JLR Papers in Press, April 14, 2006.

L. Ottosson, M. Sunnerhagen, E. Ehrenborg, 2006, Journal of Lipid Research.

A common functional polymorphism in the promoter region of the MTP gene influences the plasma LDL level

A. Hamsten, P. Eriksson, F. Karpe, 1998 .

An ex vivo RT-qPCR-based assay for human peripheral leukocyte responsiveness to glucocorticoids in surgically induced inflammation

L. Strömmer, A. Wikström, M. Uzunel, 2015, Journal of inflammation research.

The tyrosine kinase inhibitor nilotinib targets the discoidin domain receptor DDR2 in calcific aortic valve stenosis

A. Franco‐Cereceda, P. Eriksson, M. Bäck, 2022, British journal of pharmacology.

Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts.

L. Groop, P. Talmud, B. Isomaa, 2009, European journal of endocrinology.

Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men

A. Hamsten, F. Karpe, C. Packard, 2003, Journal of internal medicine.

Stereotyping at the undergraduate level revealed during interprofessional learning between future doctors and biomedical scientists

Max Scheja, M. Lewitt, E. Ehrenborg, 2010, Journal of interprofessional care.

Overexpression of 11beta-hydroxysteroid dehydrogenase-1 in adipose tissue is associated with acquired obesity and features of insulin resistance: studies in young adult monozygotic twins.

A. Rissanen, A. Hamsten, K. Pietiläinen, 2004, The Journal of clinical endocrinology and metabolism.

Troglitazone stimulates IGF-binding protein-1 by a PPARγ-independent mechanism

J. Skogsberg, M. Lewitt, K. Hall, 2003 .

Genes Associated with Increased Fasting Glucose in Patients with Schizophrenia Spectrum Disorders

C. Östenson, H. Gu, D. Erlinge, 2016 .

Allelic variation in the promoter region of the LDL receptor gene: analysis of an African-specific variant in the FP2 cis-acting regulatory element.

M. Hayden, D. Rubinsztein, P. Amouyel, 2003, Molecular and cellular probes.

Genetic variants of increased waist circumference in psychosis

C. Östenson, H. Gu, G. Edman, 2017, Psychiatric genetics.

Uva-dare (digital Academic Repository) a Single Ser 259arg Mutation in the Gene for Lipoprotein Lipase Causes Chylomicronemia in Moroccans of Berber Ancestry a Single Ser259arg Mutation in the Gene for Lipoprotein Lipase Causes Chylomicronemia in Moroccans of Berber Ancestry

J. Kastelein, L. Foubert, P. Benlian, 2022 .

Novel mutations in microsomal triglyceride transfer protein including maternal uniparental disomy in two patients with abetalipoproteinemia

M. Tosi, E. Ehrenborg, C. Duponchel, 2012, Clinical genetics.

PPARdelta activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells.

A. Hamsten, J. Skogsberg, B. Glinghammar, 2003, Biochemical and biophysical research communications.

IGFBP-1 protease activity and IGFBP-1 fragments in a patient with multiple myeloma.

H. Jörnvall, M. Ståhlberg, M. Lewitt, 2009, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

PPARδ increases expression of the human apolipoprotein A-II gene in human liver cells

J. Skogsberg, B. Glinghammar, E. Ehrenborg, 2008 .

Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed‐forward loop between LXR and autophagy

J. Borén, S. Humphries, A. Smit, 2019, Journal of internal medicine.

Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts.

L. Groop, P. Talmud, B. Isomaa, 2009, European journal of endocrinology.