K. Keef

发表

ANO1 in intramuscular interstitial cells of Cajal plays a key role in the generation of slow waves and tone in the internal anal sphincter

S. Ward, K. Sanders, M. Zhu, 2017, The Journal of physiology.

Cotransmission from sympathetic vasoconstrictor neurons: differences in guinea-pig mesenteric artery and vein

S. Ward, V. Mutafova-Yambolieva, J. Bobalova, 2000, Autonomic Neuroscience.

Expression and function of KCNH2 (HERG) in the human jejunum.

A. Farrelly, S. Ro, B. Callaghan, 2003, American journal of physiology. Gastrointestinal and liver physiology.

in rabbit portal vein myocytes by recombinant G? subunits

B. Callaghan, J. Zhong, K. Keef, 2006 .

Muscarinic M2 Receptor Stimulation of Cav1.2b Requires Phosphatidylinositol 3-Kinase, Protein Kinase C, and c-Src

B. Callaghan, S. D. Koh, K. Keef, 2004, Circulation research.

Muscarinic M 2 Receptor Stimulation of Cav 1 . 2 b Requires Phosphatidylinositol 3-Kinase , Protein Kinase C , and cSrc

B. Callaghan, S. D. Koh, K. Keef, 2004 .

Rhythmic calcium transients in smooth muscle cells of the mouse internal anal sphincter

S. Baker, C. Cobine, K. Keef, 2020, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Inhibitory Neural Regulation of the Ca2+ Transients in Intramuscular Interstitial Cells of Cajal in the Small Intestine

K. Sanders, S. Baker, C. Cobine, 2018, Front. Physiol..

Relationship between interstitial cells of Cajal, fibroblast-like cells and inhibitory motor nerves in the internal anal sphincter

S. Ward, K. Sanders, G. Hennig, 2011, Cell and Tissue Research.

Distribution of interstitial cells of Cajal in tunica muscularis of the canine rectoanal region.

S. Ward, K. Keef, K. Horiguchi, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Interstitial cells of Cajal and electrical activity in ganglionic and aganglionic colons of mice.

S. Ward, K. Sanders, M. Gershon, 2002, American journal of physiology. Gastrointestinal and liver physiology.

Interstitial cells of Cajal in the cynomolgus monkey rectoanal region and their relationship to sympathetic and nitrergic nerves.

S. Ward, G. Hennig, W. Hatton, 2010, American journal of physiology. Gastrointestinal and liver physiology.

Functional evidence for purinergic inhibitory neuromuscular transmission in the mouse internal anal sphincter.

S. Ward, K. Keef, M. Fong, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Loss of the &agr;7 Integrin Promotes Extracellular Signal-Regulated Kinase Activation and Altered Vascular Remodeling

P. Scowen, C. Singer, W. Gerthoffer, 2007, Circulation research.

Comparison of central versus peripheral nerve pathways to the guinea pig inferior mesenteric ganglion determined electrophysiologically after chronic nerve section.

D. Kreulen, K. Keef, 1990, Journal of the autonomic nervous system.

Cyclic GMP-dependent Protein Kinase Activates Cloned BKCa Channels Expressed in Mammalian Cells by Direct Phosphorylation at Serine 1072*

B. Horowitz, F. Britton, M. Fukao, 1999, The Journal of Biological Chemistry.

Basal activation of ATP-sensitive potassium channels in murine colonic smooth muscle cell.

K. Sanders, B. Horowitz, S. D. Koh, 1998, Biophysical journal.

Characterization of delayed rectifier K+ currents in rabbit coronary artery cells near resting membrane potential.

T. Ishikawa, D. Eckman, K. Keef, 1997, Canadian journal of physiology and pharmacology.

Intracellular divalent cations block smooth muscle K+ channels.

T. Ishikawa, J. Hume, K. Keef, 1993, Circulation research.

Comparison of the actions of acetylcholine and BRL 38227 in the guinea‐pig coronary artery

D. Eckman, K. Keef, J. Frankovich, 1992, British journal of pharmacology.

Measurements of the membrane potential of arterial smooth muscle in anesthetized animals and its relationship to changes in artery diameter.

T. Neild, K. Keef, 1985, Microvascular research.

Modulation of K+ and Ca2+ channels by histamine H1‐receptor stimulation in rabbit coronary artery cells.

T. Ishikawa, J. Hume, K. Keef, 1993, The Journal of physiology.

Mechanism of cyclic AMP-induced hyperpolarization in canine colon.

K. Sanders, C. Du, K. Keef, 1994, The Journal of pharmacology and experimental therapeutics.

Regulation of BK(Ca) channels expressed in human embryonic kidney 293 cells by epoxyeicosatrienoic acid.

B. Horowitz, M. Fukao, K. Keef, 2001, Molecular pharmacology.

Electrophysiological Mechanisms of Minoxidil Sulfate-Induced Vasodilation of Rabbit Portal Vein

N. Leblanc, J. Hume, K. Keef, 1989, Circulation research.

An unusual Ca(2+) entry pathway activated by protein kinase C in dog splenic artery.

A. D. Smith, L. Gregory, K. Keef, 1999, The Journal of pharmacology and experimental therapeutics.

Adenosine-induced hyperpolarization in guinea pig coronary artery involves A2b receptors and KATP channels.

V. Mutafova-Yambolieva, K. Keef, 1997, American journal of physiology. Heart and circulatory physiology.

Endothelium‐dependent relaxation and hyperpolarization in guinea‐pig coronary artery: role of epoxyeicosatrienoic acid

D. Eckman, K. Keef, N. Hopkins, 1998, British journal of pharmacology.

Cyclic GMP‐independent relaxation and hyperpolarization with acetylcholine in guinea‐pig coronary artery

D. Eckman, I. Buxton, K. Keef, 1994, British journal of pharmacology.

Spatial organization and coordination of slow waves in the mouse anorectum

S. Ward, K. Hall, C. Cobine, 2014, The Journal of physiology.

Anchoring protein is required for cAMP-dependent stimulation of L-type Ca(2+) channels in rabbit portal vein.

J. Hume, J. Zhong, K. Keef, 1999, The American journal of physiology.

Anchoring protein is required for cAMP-dependent stimulation of L-type Ca2+ channels in rabbit portal vein.

J. Hume, J. Zhong, K. Keef, 1999, American journal of physiology. Cell physiology.

Excitatory motor innervation in the canine rectoanal region: Role of changing receptor populations

K. O’Driscoll, I. Buxton, K. Keef, 2002, British journal of pharmacology.

Modulation of cholinergic neuromuscular transmission by nitric oxide in canine colonic circular smooth muscle.

K. Keef, M. Khoyi, M. Rae, 1998, The American journal of physiology.

Multiple P2Y receptors mediate contraction in guinea pig mesenteric vein.

T. K. Harden, V. Mutafova-Yambolieva, K. Keef, 2000, General pharmacology.

The mechanism and spread of pacemaker activity through myenteric interstitial cells of Cajal in human small intestine.

S. Ward, K. Sanders, G. Hennig, 2007, Gastroenterology.

Control of motility patterns in the human colonic circular muscle layer by pacemaker activity

K. Sanders, K. Keef, N. Fleming, 1998, The Journal of physiology.

Parallel pathways mediate inhibitory effects of vasoactive intestinal polypeptide and nitric oxide in canine fundus

K. Sanders, K. Keef, B. Hagen, 1999, British journal of pharmacology.

rapid communication Anchoring protein is required for cAMP-dependent stimulation of L-type Ca 2 1 channels in rabbit portal vein

J. Hume, J. Zhong, K. Keef, 1999 .

Involvement of cyclic GMP in non‐adrenergic, non‐cholinergic inhibitory neurotransmission in dog proximal colon

S. Ward, K. Sanders, I. Buxton, 1992, British journal of pharmacology.

Modification of the response to nerve stimulation in small arteries of guinea‐pig caused by distension of the artery.

T. Neild, K. Keef, 1982, The Journal of physiology.

Cellular mediators of nitrergic neurotransmission in GI smooth muscles: no easy answer

K. Sanders, K. Keef, K. Sanders, 2015, The Journal of physiology.

Nitrergic neuromuscular transmission in the mouse internal anal sphincter is accomplished by multiple pathways and postjunctional effector cells.

S. Ward, K. Sanders, C. Cobine, 2014, American journal of physiology. Gastrointestinal and liver physiology.

Purinergic relaxation and hyperpolarization in guinea pig and rabbit coronary artery: role of the endothelium.

D. Eckman, K. Keef, J. Pasco, 1992, The Journal of pharmacology and experimental therapeutics.

Regulation of L‐type Ca2+ channels in rabbit portal vein by G protein αs and βγ subunits

C. Dessauer, J. Hume, J. Zhong, 1999 .

Regulation of cardiac and smooth muscle Ca(2+) channels (Ca(V)1.2a,b) by protein kinases.

J. Hume, J. Zhong, K. Keef, 2001, American journal of physiology. Cell physiology.

β‐Adrenergic receptor stimulation of L‐type Ca2+ channels in rabbit portal vein myocytes involves both αs and βγ G protein subunits

J. Hume, J. Zhong, K. Keef, 2001 .

Modulation of Ca2+ channels by cyclic nucleotide cross activation of opposing protein kinases in rabbit portal vein.

J R Hume, K D Keef, V. Ruiz-Velasco, 1998, Circulation research.

Regulation of Ca2+ channels by cAMP and cGMP in vascular smooth muscle cells.

T. Ishikawa, J. Hume, K. Keef, 1993, Circulation research.

Basal release of nitric oxide induces an oscillatory motor pattern in canine colon.

K. Sanders, K. Keef, T. K. Smith, 1997, The Journal of physiology.

Enteric inhibitory neural regulation of human colonic circular muscle: role of nitric oxide.

S. Ward, K. Sanders, C. Du, 1993, Gastroenterology.

Comparison of neurotransmission with nerve trunk and transmural field stimulation in guinea‐pig mesenteric artery.

D. Kreulen, K. Keef, O. Hottenstein, 1991, The Journal of physiology.

Electrical Responses of Guinea Pig Coronary Artery to Transmural Stimulation

D. Kreulen, K. Keef, 1988, Circulation research.

Electrophysiological and neuromuscular relationships in extramural blood vessels

D. Kreulen, K. Keef, 2011 .

NG-nitro L-arginine methyl ester and other alkyl esters of arginine are muscarinic receptor antagonists.

I L Buxton, D. Eckman, D J Cheek, 1993, Circulation research.

Relationship between nitric oxide and vasoactive intestinal polypeptide in enteric inhibitory neurotransmission

C. Shuttleworth, K. Sanders, N. Publicover, 1994, Neuropharmacology.

Nitrergic Neurotransmission in the Enteric Nervous System

K. Sanders, K. Keef, 2000 .

Functional role of vasoactive intestinal polypeptide in inhibitory motor innervation in the mouse internal anal sphincter

S. Saxton, C. Cobine, K. Keef, 2013, The Journal of physiology.

A novel intramuscular Interstitial Cell of Cajal is a candidate for generating pacemaker activity in the mouse internal anal sphincter

S. Ward, K. Sanders, S. Baker, 2020, Scientific Reports.

Species dependent differences in the actions of sympathetic nerves and noradrenaline in the internal anal sphincter

C. Cobine, K. Keef, M. Fong, 2007, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Control of Motility in the Internal Anal Sphincter

C. Cobine, K. Keef, Caroline A Cobine, 2019, Journal of neurogastroenterology and motility.

Generation of Spontaneous Tone by Gastrointestinal Sphincters.

C. Cobine, K. Keef, Caroline A Cobine, 2019, Advances in experimental medicine and biology.

Relaxation induced by KCl, NaCl and sucrose in rabbit coronary arteries

G. Ross, K. Keef, 1987, Pflügers Archiv.

Inhibition of nitric oxide synthesis reveals non‐cholinergic excitatory neurotransmission in the canine proximal colon

K. Sanders, K. Keef, C. Shuttleworth, 1993, British journal of pharmacology.

Ca(2+)-induced inhibition of 45Ca2+ influx and Ca2+ current in smooth muscle of the rat vas deferens.

T. Ishikawa, K. Keef, M. Khoyi, 1996, The American journal of physiology.

Changes in neuromuscular transmission in the W/Wv mouse internal anal sphincter

Á. M. Duffy, C. Cobine, K. Keef, 2012, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Roles of peptides in enteric neuromuscular transmission

K. Keef, C. Shuttleworth, 1995, Regulatory Peptides.

Beta-adrenergic inhibition of electrical and mechanical activity in canine colon: role of cAMP.

S. Ward, K. Sanders, W. Gerthoffer, 1993, The American journal of physiology.

Electrical and mechanical effects of acetylcholine and substance P in canine colon

S. Ward, K. Sanders, K. Keef, 1992 .

Electrical activity induced by nitric oxide in canine colonic circular muscle.

S. Ward, K. Sanders, K. O’Driscoll, 2002, American journal of physiology. Gastrointestinal and liver physiology.

Differential expression of P2X‐purinoceptor subtypes in circular and longitudinal muscle of canine colon

K. Sanders, B. Horowitz, K. Keef, 2005, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

Role of L-type calcium channels and PKC in active tone development in rabbit coronary artery.

B. Callaghan, C. Cobine, K. Keef, 2007, American journal of physiology. Heart and circulatory physiology.

Action of alpha 2A-adrenergic receptors in circular smooth muscle of canine proximal colon.

I. Buxton, L. Zhang, M. E. Bradley, 1992, American Journal of Physiology.

Comparison of inhibitory neuromuscular transmission in the Cynomolgus monkey IAS and rectum: special emphasis on differences in purinergic transmission

M. Mckechnie, C. Cobine, K. Keef, 2018, The Journal of physiology.

Regulation of Ca 2 + Channels by cAMP and cGMP in Vascular Smooth Muscle Cells

T. Ishikawa, J. Hume, K. Keef, 2005 .

Frequency dependent alpha(2)-adrenoceptor mediated modulation of excitatory junction potentials in guinea-pig mesenteric artery.

V. Mutafova-Yambolieva, K. Keef, 2001, European Journal of Pharmacology.

Effect of ACh on electrical and mechanical activity in guinea pig coronary arteries.

K. Keef, S. Bowen, 1989, American Journal of Physiology.

Septal interstitial cells of Cajal conduct pacemaker activity to excite muscle bundles in human jejunum.

S. Ward, K. Sanders, G. Hennig, 2007, Gastroenterology.

Spatial localization and properties of pacemaker potentials in the canine rectoanal region.

S. Ward, A. Farrelly, V. Mutafova-Yambolieva, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Modulation of cholinergic neuromuscular transmission by nitric oxide in canine colonic circular smooth muscle.

K. Keef, M. Khoyi, M. Rae, 1998, American journal of physiology. Gastrointestinal and liver physiology.

Peripheral nerve pathways to neurons in the guinea pig inferior mesenteric ganglion determined electrophysiologically after chronic nerve section.

D. Kreulen, K. Keef, 1990, Journal of the autonomic nervous system.

Template switching within exons 3 and 4 of KV11.1 (HERG) gives rise to a 5' truncated cDNA.

A. Farrelly, T. Ordog, K. Keef, 2006, Biochemical and biophysical research communications.

Venous mechanoreceptor input to neurones in the inferior mesenteric ganglion of the guinea‐pig.

D. Kreulen, K. Keef, 1986, The Journal of physiology.

potentials in the canine rectoanal region Spatial localization and properties of pacemaker

S. Ward, A. Farrelly, V. Mutafova-Yambolieva, 2016 .

Changes in neuromuscular transmission in the W/Wv mouse internal anal sphincter

K. Keef, A. M. Duffy, Caroline A Cobine, 2012, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.