Y. Kanaoka

发表

Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence

Yuichi Kanaoka, Takashi Miyata, Michael A. Raftery, 1984, Nature.

Total synthesis of aspidospermine.

T. Ōishi, Y. Kanaoka, Y. Ban, 1965, Tetrahedron letters.

A Novel Fluorometric Ultramicro Determination of Serum γ-Glutamyltranspeptidase Activity

Tetsuo Takahashi, H. Nakayama, Y. Kanaoka, 1981 .

Synthesis of a new fluorogenic substrate for cystine aminopeptidase.

T. Takahashi, H. Nakayama, Y. Kanaoka, 1982, Chemical & pharmaceutical bulletin.

Hydrolysis of N-Substituted Maleimides : Stability of Fluorescence Thiol Reagents in Aqueous Media

M. Machida, Y. Kanaoka, M. Machida, 1977 .

Fluorescence-labeled Streptomyces subtilisin inhibitor : analysis of the interaction with subtilisin and Streptomyces griseus proteases

Y. Kanaoka, K. Tanizawa, Sinya Watanabe, 1990 .

Remote Photocyclization. Photochemical Macrocyclic Synthesis with N-(w-Methylanilino)alkylphthalimides

M. Machida, Y. Kanaoka, Haruko Takeuchi, 1977 .

Photochemical cyclization of N-2-alkenyl- and N-3-alkenylphthalimides

M. Machida, K. Maruyama, K. Fukuyama, 1978 .

Photoreactions of cyclic imides. Examples of synthetic organic photochemistry

Y. Kanaoka, 1978 .

Synthesis of a Key Fluorogenic Amide, L-Arginine-4-methylcoumaryl-7-amide (L-Arg-MCA) and Its Derivatives. Fluorescence Assays for Trypsin and Papain

Tetsuo Takahashi, S. Sakakibara, H. Nakayama, 1977 .

Inverse substrates for trypsin and trypsin-like enzymes

Y. Kanaoka, K. Tanizawa, W. Lawson, 1987 .

A VERSATILE APPROACH FOR FUNCTIONALIZATION OF 3-ARYL-3-TRIFLUOROMETHYLDIAZIRINE PHOTOPHOR

M. Hashimoto, Y. Hatanaka, Y. Kanaoka, 1997 .

A Novel Family of Aromatic Diazirines for Photoaffinity Labeling

M. Hashimoto, Y. Hatanaka, H. Nakayama, 1994 .

A novel biotinylated heterobifunctional cross-linking reagent bearing an aromatic diazirine.

M. Hashimoto, Y. Hatanaka, Y. Kanaoka, 1994, Bioorganic & medicinal chemistry.

A Rapid and Efficient Method for Identifying Photoaffinity Biotinylated Sites within Proteins

M. Hashimoto, Y. Hatanaka, Y. Kanaoka, 1998 .

Fluorescence and structure of proteins as measured by incorporation of fluorophore. II. Synthesis of maleimide derivatives as fluorescence-labeled protein-sulfhydryl reagents.

M. Machida, Y. Kanaoka, Y. Ban, 1967, Chemical & pharmaceutical bulletin.

Synthesis of a Carbon-linked CMP-NANA Analog and Its Inhibitory Effects on GM3 and GD3 Synthases

M. Hashimoto, Y. Hatanaka, K. Hidari, 1996 .

A novel fluorometric ultramicro determination of serum leucine aminopeptidase using a coumarine derivative.

Y. Kanaoka, T. Sekine, T. Namihisa, 1978, Clinica chimica acta; international journal of clinical chemistry.

Fluorescence and structures of proteins as measured by incorporation of fluorophore

M. Machida, Y. Kanaoka, T. Sekine, 1970 .

'Inverse' substrates for butyrylcholinesterase.

Y. Kanaoka, K. Tanizawa, M. Nozawa, 1980, Biochimica et biophysica acta.

A Facile Synthesis of N-(2- and 4-Pyridyl)indoles

Y. Kanaoka, K. Seki, K. Ohkura, 1994 .

Preparation of anti-peptide antibodies and their application to the cardiac Na+ channel

T. Hanawa, H. Nakayama, Y. Kanaoka, 1993 .

Chemical and immunological characterization of binding sites for tetrodotoxin and dihydropyridine that are in close proximity to the external mouth of ion pore in the sodium and calcium channels

Y. Hatanaka, H. Nakayama, Y. Kanaoka, 1992 .

Photolabile μ‐conotoxins with a chromogenic phenyldiazirine

T. Abe, Y. Hatanaka, H. Nakayama, 1990 .

Photocyclizations of pharmacodynamic amines. V. Unusual rearrangements of the mescaline skeleton.

I. Karle, B. Witkop, Y. Kanaoka, 1970, Journal of the American Chemical Society.

Photocyclizations of pharmacodynamic amines. 3. Three-dimensional structure of 7-hydroxy-1,9,10-trimethoxy-4-azabicyclo [5.2.2] undeca-8,10-dien-3-one from mescaline.

I. Karle, B. Witkop, Y. Kanaoka, 1969, Journal of the American Chemical Society.

Proteolytic enzymes. VI. Aromatic amidines as competitive inhibitors of trypsin.

Y. Kanaoka, K. Tanizawa, S. Ishii, 1971, Journal of biochemistry.

The histochemical distribution of protein bound sulfhydryl groups in human epidermis by the new staining method.

Y. Kanaoka, H. Ogawa, T. Sekine, 1979, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Multifunctional cross-linking reagents. I. Synthesis and properties of novel photoactivable, thiol-directed fluorescent reagents.

H. Nakayama, Y. Kanaoka, T. Sekine, 1984, Chemical & pharmaceutical bulletin.

Transition-state inhibition of thrombin and trypsin by amidinophenylpyruvates.

Y. Kanaoka, K. Tanizawa, W. Lawson, 1985, Biological chemistry Hoppe-Seyler.

Fluorescent staining of microfilaments with heavy meromyosin labeled with N-(7-dimethylamino-4-methylcoumarinyl) maleimide.

Y. Kanaoka, T. Sekine, T. Namihisa, 1980, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Heavy Meromyosin Labeled with N -(7-Dimethylamino-4-Methylcoumarinyl) al'

Y. Kanaoka, T. Sekine, T. Namihisa, 1980 .

A photoaffinity labeling of the active site of α‐chymotrypsin with TPDK

H. Nakayama, Y. Kanaoka, 1973 .

"Inverse substrates" for trypsin-like enzymes.

Y. Kanaoka, K. Tanizawa, M. Nozawa, 1980, Journal of pharmacobio-dynamics.

New fluorogenic, photoactivable, heterobifunctional crosslinking thiol reagents.

Y. Kanaoka, T. Sekine, T. Ueno, 1984, Analytical biochemistry.

Efficient synthetic method for ethyl (+)-(2S,3S)-3-[(S)-3-methyl- 1-(3-methylbutylcarbamoyl)butylcarbamoyl]-2-oxiranecarb oxylate (EST), a new inhibitor of cysteine proteinases.

M. Murata, Y. Kanaoka, M. Tamai, 1987, Chemical & pharmaceutical bulletin.

A novel chiral microenvironmental probe at the active site of trypsin. Extrinsic cotton effects of acyl-trypsin possessing an enantiomeric pair of chromophores.

B. Witkop, H. Nakayama, Y. Kanaoka, 1980, European journal of biochemistry.

Fluorescence and Structure of Proteins as measured by Incorporation of Fluorophore. III. Fluorescence Characteristics of N-[p-(2-Benzoxazolyl) phenyl] maleimide and the Derivatives

M. Machida, H. Kokubun, Y. Kanaoka, 1968 .

Differentiation of tryptic enzymes based on enantiomeric specificity at the deacylation step

H. Yamada, Y. Kanaoka, K. Tanizawa, 1988, FEBS letters.

Behavior of trypsin and related enzymes toward amidinophenyl esters.

Y. Kanaoka, K. Tanizawa, H. Moriya, 1981, Journal of pharmacobio-dynamics.

Trypsin substrates derived from benzamidine: application to active site titration and isolation of acyl-enzyme intermediate.

Y. Kanaoka, K. Tanizawa, S. Ishii, 1968, Biochemical and biophysical research communications.

Photocyclization of benzanilides to phenanthridones with elimination of the ortho-methoxy-group

Y. Kanaoka, K. Itoh, 1973 .

Photo-Arylation. IV. Synthesis of 2-Arylpyridines by Photo-Reaction of 2-Iodopyridine with Substituted Benzenes

Y. Kanaoka, C. Yoshida, K. Seki, 1985 .

Ionization Potentials of Some Organic Molecules. V. Heterocyclic Compounds Containing Nitrogen

Y. Kanaoka, K. Higasi, H. Baba, 1957 .

Photocycloadditions of N-Methylmonothiophthalimide with Styrene Derivatives Accompanied by 1,2-Dithiane Formation

M. Machida, Y. Kanaoka, K. Oda, 1985 .

Chemical Identification of Binding Sites for Calcium Channel Antagonists

H. Nakayama, Y. Kanaoka, 1996 .

A Facile Synthesis of 2-Substituted Benzoxazoles

Y. Kanaoka, M. Terashima, M. Ishii, 1982 .

A Facile Synthesis of 2-Substituted Benzoxazoles

Y. Kanaoka, M. Terashima, M. Ishii, 1982 .

Polyphosphate Ester as a Synthetic Agent. XII. A Convenient Synthesis of Nitriles by the Dehydration of Amides with PPE

T. Kuga, Y. Kanaoka, K. Tanizawa, 1970 .

Photoreactions of Succinimides with an N-Acyl Group in the Side Chain. Synthesis and Stereochemistry of Tricyclic Pyrrolo[1, 2-α]pyrazine Ring Systems

M. Machida, Y. Nishibata, Y. Kanaoka, 1986 .

Photochemical Synthesis of Multicyclic Fused Imidazolidines, Hydropyrazines, and Hydro-1,4-diazepines

M. Machida, Y. Kanaoka, H. Takechi, 1982 .

Photoreaction of 4-Iodopyridine with Heteroaromatics

Y. Kanaoka, K. Seki, K. Ohkura, 1986 .

Polyphosphate Ester as a Synthetic Agent. XIII. Syntheses of 2-Substituted Benzoxazoles and Benzthiazoles with PPE

Y. Kanaoka, O. Yonemitsu, T. Hamada, 1970 .

Synthesis of 2,3,9,10-Tetramethoxy-5,6,6a,7,12,13-hexahydro-13- methyldibenzo(b,flquinolizinium Iodide, Chem.Pharm.Bull., 7, 595-597 (1959).

Y. Kanaoka, Kenta Higashi, I. Omura, 2003 .

The Plancher rearrangement of 2,3-disubstituted 3H-indoles

Y. Kanaoka, O. Yonemitsu, K. Miyashita, 1969 .

Photoreaction of phthalimides possessing an ortho-methylphenyl group in their N-side chain: synthesis of tetracyclic nitrogen heterocycles

M. Machida, Y. Kanaoka, H. Takechi, 1987 .

Photochemistry of the phthalimide system. VI. Photocyclization of N-alicyclic phthalimides. Synthesis of multicyclic benzazepine systems

I. Karle, B. Witkop, J. Flippen, 1974 .

POLYPHOSPHATE ESTERS AS SYNTHETIC REAGENT. I. SYNTHESIS OF 2-SUBSTITUTED BENZIMIDAZOLES.

Y. Kanaoka, Y. Ban, O. Yonemitsu, 1964, Chemical & pharmaceutical bulletin.

Intramolecular Photoreactions of Phthalimide-Alkene Systems. Oxetane Formation of N-(ω-Indol-3-ylalkyl)phthalimides

M. Machida, Y. Kanaoka, Haruko Takechi, 1988 .

PHOTOCHEMISTRY OF THE AMIDE SYSTEM. V. SYNTHETIC PHOTOCHEMISTRY WITH HETEROCYCLIC ANILIDES. STEREOCHEMISTRY OF THE INTRAMOLECULAR 1,5-HYDROGEN SHIFTS IN NONOXIDATIVE PHOTOCYCLIZATION OF BENZO(B)THIOPHENE-2-CARBOXANILIDES

I. Karle, Y. Hatanaka, B. Witkop, 1976 .

Stereochemistry of Nonoxidative Photocyclization of Indole-2-carboxanilides to an Indolo[2,3-c]quinoline System

Y. Hatanaka, Y. Kanaoka, S. Nakao, 1976 .

Photochemistry of the amide system. V. Synthetic photochemistry with heterocyclic anilides. Stereochemistry of the intramolecular 1,5-hydrogen shifts in nonoxidative photocyclization of benzo[b]thiophene-2-carboxanilides

I. Karle, Y. Hatanaka, B. Witkop, 1975 .

Photocyclization of n-[ω-(cycloalken-1-yl)alkyl]-and n-[ω-(inden-3-yl)alkyl]phthalimides : Synthesis of spiro-nitrogen multicyclic systems

M. Machida, Y. Kanaoka, K. Oda, 1985 .

Intramolecular Photoreactions of Phthalimide-Alkene Systems. Macrocyclic Synthesis through the Remote Paterno-Buchi Reaction of Phthalimide with Indole Derivatives

M. Machida, Y. Kanaoka, H. Takechi, 1994 .

Application of Remote Photocyclization with a Pair System of Phthalimide and Methylthio Groups. A Photochemical Synthesis of Cyclic Peptide Models

Y. Hatanaka, Y. Kanaoka, H. Nakai, 1992 .

A removable functional group in a photochemical macrocyclic synthesis : Remote photocyclization with a pair system of phthalimide and 1,3-dithiolanyl groups

Y. Hatanaka, Y. Kanaoka, H. Nakai, 1982 .

Photodecarboxylation of N-Phthaloyl-α-amino Acids

Y. Hatanaka, Y. Kanaoka, H. Nakai, 1982 .

Intramolecular photocycloaddition of 3-substituted dithiosuccinimides: facile synthesis and the crystal structure of highly strained multicyclic fused thietane system

M. Machida, Y. Nishibata, Y. Kanaoka, 1986 .

Photoreaction of N-substituted monothiophthalimides with styrene derivatives. An example of formation and fission of the thietane ring

M. Machida, Y. Kanaoka, K. Oda, 1986 .

Intermolecular Photocycloaddition of Ring-Substituted Cyclic Dithioimides with 2,3-Dimethyl-2-butene: A Facile Synthesis of Spiro-Thietanes

M. Machida, Y. Kanaoka, K. Oda, 1986 .

INTRAMOLECULAR PHOTOCYCLOADDITION OF THIOSUCCINIMIDES WITH ALKENYL N-SIDE CHAINS : SYNTHESIS OF STRAINED MULTICYCLIC SPIRO-THIETANES

M. Machida, Y. Kanaoka, K. Oda, 1985 .

Photocycloaddition of arylcarbothioamides with unsaturated systems. Synthesis of 3,5-diaryl-1,2,4-thiadiazoles and 3-aryl-4,4,5,5-tetramethylisothiazolines via photogenerated nitrile sulfides☆

M. Machida, Y. Kanaoka, K. Oda, 1984 .

Application of the remote photocyclization with a pair system of phthalimide and methylthio groups

Y. Hatanaka, Y. Kanaoka, H. Nakai, 1983 .

Photocyclization of ω-Anilinoalkylphthalimides : A Photochemical Macrocyclic Synthesis

M. Machida, Y. Kanaoka, H. Takechi, 1982 .

Photochemical cyclization of N-2-alkenyl- and N-3-alkenylphthalimides

M. Machida, K. Maruyama, K. Fukuyama, 1978 .

A synthetic approach to cyclic peptide models by regioselective remote photocyclization of sulfide-containing phthalimides☆☆☆

Y. Kanaoka, H. Nakai, T. Mizoguchi, 1976 .

Photochemistry of the phthalimide system. VII. Regioselective remote photocyclization. Examples of a photochemical macrocyclic synthesis with sulfide-containing phthalimides

Y. Hatanaka, Y. Kanaoka, Y. Sato, 1976 .

Photochemistry of the phthalimide system. IV. Photocyclization of N-alkylphthalimides to benzazepinone lactams: Unusual two-fold norrish type II reactions☆

Y. Kanaoka, K. Kôyama, H. Nakai, 1973 .

Photo-dearomatization of n-methylphthalimides: an example of nucleophilic aromatic photoaddition of alcohol1,2

I. Karle, Y. Hatanaka, E. Duesler, 1985 .

Photoarylation. I. Photochemical Synthesisn of Benzothieno[2,3-c][1,x]diazanaphthalene Systems by Intramolecular Dehydrochlorination

Y. Kanaoka, K. Itoh, M. Terashima, 1977 .

Polyphosphate Ester as a Synthetic Agent. XI. Synthesis of 2-(1'-Aminoalkyl) benzimidazoles from N-Benzoylamino Acids

Y. Kanaoka, O. Yonemitsu, K. Tanizawa, 1969 .

Polyphosphate ester as a synthetic agent—XI

Y. Kanaoka, Y. Ban, O. Yonemitsu, 1969 .

Polyphosphate Ester as a Synthetic Agent. VII. The Beckmann Rearrangement and Formation of Amidines with PPE

Y. Kanaoka, Y. Ban, O. Yonemitsu, 1968 .

Polyphosphate ester as a synthetic agent. VI. The Bischler-Napieralski reaction of tryptamine and tryptophan derivates by means of polyphosphate ester.

Y. Kanaoka, Y. Ban, E. Sato, 1967, Chemical & pharmaceutical bulletin.

Polyphosphate Ester as a Synthetic Agent. V. The Fischer Indole Synthesis with Polyphosphate Ester

Y. Kanaoka, Y. Ban, O. Yonemitsu, 1966 .

Bischler-napieralski reaction by means of polyphosphate esters and synthesis of 5H-2-benzazepine derivatives☆☆☆

Y. Kanaoka, Y. Ban, O. Yonemitsu, 1964 .

Organic Photochemistry of Imides

Y. Kanaoka, 1975 .

Enantiomeric specificity at the deacylation process of tryptic catalysis.

H. Yamada, Y. Kanaoka, K. Tanizawa, 1987, Biochimica et biophysica acta.

Photo-Affinity Labeling. II. Photolysis of Amido Derivatives of Nitrophenyl Azides

H. Nakayama, Y. Kanaoka, M. Nozawa, 1979 .

Direct conversion of N-methylindoles into indoxyl, oxindole, and dioxindole o-benzoates

Y. Kanaoka, S. Hariya, M. Aiura, 1971 .

Photochemistry of the Semicyclic Imide System. I. Evidence for Competitive Type I and Type II Processes

M. Machida, A. Sakushima, Y. Kanaoka, 1981 .

Photoaddition of olefins to cyclic imides: intermolecular oxetane formation and ring expansion

Y. Hatanaka, Y. Kanaoka, Kenji Yoshida, 1979 .

Photochemistry of the Phthalimide System, 37. Thiazacycloalkanols by Photocyclization of S‐Substituted N‐(Thioalkyl)phthalimides

Y. Hatanaka, Y. Kanaoka, H. Nakai, 1985 .

Organic fluorescent reagents: XIV. Novel fluorogenic substrates for microdetermination of chymotrypsin and aminopeptidase: Bimane fluorescence appears after hydrolysis

Y. Kanaoka, E. Kosower, E. Sato, 1988 .

Photochemistry of N-But-3-enyl Thiophthalimides. Intramolecular Thietane Formation

M. Machida, Y. Kanaoka, K. Oda, 1992 .

Photochemistry of the nitrogen-thiocarbonyl systems. Application to syntheses of nitrogen-heterocycles.

M. Machida, Y. Kanaoka, K. Oda, 1986 .

EFFECTIVE SYNTHESIS OF OPTICALLY ACTIVE 3-PHENYL-3-(3-TRIFLUOROMETHYL) DIAZIRINYL BISHOMOPHENYLALANINE DERIVATIVES

M. Hashimoto, Yuta Murai, Y. Hatanaka, 2009 .

Biotinyl Diazirine Photophore: An Approach to High-Resolution Photoaffinity Labeling for Probing Receptor-Ligand Interface

Y. Hatanaka, Y. Kanaoka, 1998 .

A NEW CLEAVABLE CARBENE-GENERATING REAGENT WITH 3-PHENYL-3-TRIFLUOROMETHYLDIAZIRINE PHOTOPHORE

Y. Hatanaka, Y. Kanaoka, Uwe Kempin, 1998 .

Synthesis and characterization of a carbene-generating biotinylated N-acetylglucosamine for photoaffinity labeling of beta-(1-->4)-galactosyltransferase.

H. Narimatsu, S. Nishihara, Y. Kanaoka, 1996, Carbohydrate research.

Syntheses of Nitro-Substituted Aryl Diazirines. An Entry to Chromogenic Carbene Precursors for Photoaffinity Labeling

M. Hashimoto, Y. Hatanaka, H. Nakayama, 1994 .

Identification of 1,4-dihydropyridine binding regions within the alpha 1 subunit of skeletal muscle Ca2+ channels by photoaffinity labeling with diazipine.

W. Catterall, H. Glossmann, H. Nakayama, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Synthesis and characterization of a carbene-generating biotinylated lactosylceramide analog as a novel chromogenic photoprobe for GM3 synthase.

M. Hashimoto, Y. Hatanaka, K. Hidari, 1996, Chemical and pharmaceutical bulletin.

Photoaffinity labeling of the electroplax sodium channel with tetrodotoxin derivatives. II. Comparison of the photoreactivity of different photoactivable groups in the tetrodotoxin binding site.

Y. Hatanaka, H. Nakayama, Y. Kanaoka, 1990, Chemical and pharmaceutical bulletin.

An improved synthesis of 4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic acid for photoaffinity labeling

Y. Hatanaka, H. Nakayama, Y. Kanaoka, 1993 .

Chromogenic diazirine: A new spectrophotometric approach for photoaffinity labeling

Y. Hatanaka, H. Nakayama, Y. Kanaoka, 1989 .

Topographical analysis of trypsin active site structure by means of the “inverse substrate” method

Y. Kanaoka, K. Tanizawa, M. Nakano, 1987 .

Synthesis and evaluation of nitro 5-deazaflavin-pyrrolecarboxamide(s) hybrid molecules as novel DNA targeted bioreductive antitumor agents.

Y. Kanaoka, Y. Ikeuchi, Y. Mikata, 1998, Bioorganic & medicinal chemistry.

Photochemistry of N‐But‐3‐enyl Thiophthalimides. Intramolecular Thietane Formation.

M. Machida, Y. Kanaoka, K. Oda, 1992 .

Photochemistry of the Nitrogen-Thiocarbonyl Systems

M. Machida, Y. Kanaoka, K. Oda, 1987 .

Organic fluorescence reagents in the study of enzymes and proteins.

Y. Kanaoka, 1977, Angewandte Chemie.

Effective Synthesis of Optically Active 3‐Phenyl‐3‐(3‐trifluoromethyl) Diazirinyl Bishomophenylalanine Derivatives.

M. Hashimoto, Yuta Murai, Y. Hatanaka, 2009 .

An Improved Synthesis of 4-(3-(Trifluoromethyl)-3H-diazirin-3-yl) benzoic Acid for Photoaffinity Labeling.

Y. Hatanaka, H. Nakayama, Y. Kanaoka, 1994 .

A carbene-generating biotinylated lactosylceramide analog as novel photoreactive substrate for GM3 synthase

M. Hashimoto, Y. Hatanaka, K. Hidari, 1995 .

Photoaffinity labeling of the electroplax sodium channel with a photoreactive mu-conotoxin carrying a radioactive and chromogenic diazirine.

Y. Hatanaka, H. Nakayama, Y. Kanaoka, 1992, Chemical & pharmaceutical bulletin.

A Versatile Approach for Functionalization of 3‐Aryl‐3‐trifluoromethyldiazirine Photophor.

M. Hashimoto, Y. Hatanaka, Y. Kanaoka, 1998 .

Syntheses of Nitro‐Substituted Aryl Diazirines. An Entry to Chromogenic Carbene Precursors for Photoaffinity Labeling.

M. Hashimoto, Y. Hatanaka, H. Nakayama, 1994 .

A Novel Family of Aromatic Diazirines for Photoaffinity Labeling.

M. Hashimoto, Y. Hatanaka, H. Nakayama, 1994 .

Synthesis and Characterization of a Carbene-Generating Biotinylated N- Acetylglucosamine for Photoaffinity Labeling of β-(1 → 4)- Galactosyltransferase.

M. Hashimoto, Y. Hatanaka, H. Narimatsu, 1997 .

A New Cleavable Carbene-Generating Reagent with 3-Phenyl-3-trifluoromethyldiazirine Photophore.

Y. Hatanaka, Y. Kanaoka, Uwe Kempin, 1999 .

Synthesis and Properties of Diazipine, a Novel Photoaffinity Probe for Calcium Channel-Linked Dihydropyridine Receptors

H. Nakayama, Y. Kanaoka, M. Taki, 1993 .

Photolabeled sites with a tetrodotoxin derivative in the domain III and IV of the electroplax sodium channel.

Y. Hatanaka, H. Nakayama, Y. Kanaoka, 1992, Biochemical and biophysical research communications.

Diazipine, a novel photoaffinity probe for dihydropyridine receptors of calcium channels

H. Nakayama, Y. Kanaoka, M. Taki, 1991, FEBS letters.

Synthesis and Characterization of a Carbene‐Generating Biotinylated Lactosylceramide Analogue as a Novel Chromogenic Photoprobe for GM3 Synthase.

M. Hashimoto, Y. Hatanaka, K. Hidari, 1996 .

Y. Kanaoka, E. Sato, K. Kimura, 1990, Journal of pharmacobio-dynamics.

Y. Kanaoka, A. Suzuki, E. Sato, 1990, Journal of pharmacobio-dynamics.

M. Machida, Y. Kanaoka, E. Sato, 1980 .

Reaction of thiouracil and thiouridine with 2-hydroxy-5-nitrobenzyl bromide.

Y. Kanaoka, E. Sato, 1971, Biochimica et biophysica acta.

Photoreducation of 4- and 2-thiouracil and 4-thiouridine.

Y. Kanaoka, E. Sato, 1969, Tetrahedron letters.

Y. Kanaoka, E. Sato, 1974 .

Fluorescence Reagents as an Analytical Tool for Studies of Thio-nucleosides. Their Reactions with Thiouridines

M. Machida, Y. Kanaoka, E. Sato, 1980 .

Hydrogen Fluoride as an Agent in Organic Reactions. I. Degradation of Polynucleotides with Liquid Hydrogen Fluoride

Y. Kanaoka, K. Itoh, A. Nomura, 1970 .

Intramolecular photocycloaddition reaction in the 2-(4-pentenyl)-5-aryl-substituted tetrazole system

A. Padwa, Y. Kanaoka, E. Sato, 1982 .

Photoaddition of 2-thiopyridone and 2-thiopyrimidone to olefins

Y. Kanaoka, M. Hasebe, E. Sato, 1988 .

Y. Kanaoka, E. Sato, 1974 .

New Aspects of the Aromatic Photosubstitution with Iodopyridines

Y. Kanaoka, K. Seki, K. Ohkura, 1993 .

Photoinduced reactions. 39. Photochemistry of the imide system. 9. Norrish type I reaction of aliphatic cyclic imides. General reaction pattern, competition with type II processes, and some synthetic application

Y. Hatanaka, Y. Kanaoka, H. Okajima, 1979 .

Photochemistry of Succinimides with an Ether or a Thioether in Their Side-chains. g- and d-Hydrogen Abstraction

Y. Kanaoka, H. Nakai, T. Mizoguchi, 1977 .

Photochemical Synthesis of 5,10,11,12,12a, 12b-Hexahydro-12b-hydroxyisoindolo [2,1-α] benz [cd] indol-5-one

Y. Kanaoka, K. Kôyama, M. Terashima, 1978 .

Photoaddition Reactions of N-Methylphthalimide with Toluenes and Amines

Y. Hatanaka, Y. Kanaoka, K. Sakai, 1975 .

The pyridyl cation as a reactive intermediate in the photoreaction of iodopyridines with benzenes

Y. Kanaoka, K. Seki, K. Ohkura, 1989 .

Studies on calcium ion-induced conformation changes in the actin-tropomyosin-troponin system by fluorimetry. III. Changes in the conformation of tropomyosin associated with functional states.

Y. Kanaoka, T. Ohyashiki, T. Sekine, 1976, Biochimica et biophysica acta.

Studies on calcium ion-induced conformation changes in the actin-tropomyosin-troponin system by fluorimetry. II. Effect of tropomyosin, troponin and calcium ion on conformation of anilinonaphthylmaleimide-labeled f-actin.

Y. Kanaoka, T. Sekine, T. Oyashiki, 1974, Biochimica et biophysica acta.

Studies on calcium ion-induced conformation changes in the actin-tropomyosin-troponin system by fluorimetry. I. Conformation changes around the fluorescence-labeled sulfhydryl group of actin.

M. Machida, Y. Kanaoka, T. Ohyashiki, 1974, Biochimica et biophysica acta.

Photoaddition of 2-Pyridones and 2-Quinolones to Conjugated Dienes

Y. Kanaoka, E. Sato, Y. Ikeda, 1989 .

Photoaddition of 2-pyridones to conjugated dienes

Y. Kanaoka, E. Sato, Y. Ikeda, 1989 .

A topographical study of the electroplax sodium channel with site-directed antibodies.

Y. Nonomura, K. Kangawa, H. Matsuo, 1993, Biochimica et biophysica acta.

Polyphosphate ester as a synthetic agent. IV. A novel preparation of aryl esters.

Y. Kanaoka, Y. Ban, K. Tanizawa, 1967, Chemical & pharmaceutical bulletin.

Fluorescence and structure of proteins as measured by incorporation of fluorophore. IV. Synthesis and fluorescence characteristics of N-(p-(2-benzimidazolyl)phenyl) maleimide.

M. Machida, Y. Kanaoka, T. Sekine, 1970, Biochimica et Biophysica Acta.

Fluorescent thiol reagents. XII. Fluorescent tracer method for protein SH groups using N-(7-dimethylamino-4-methyl coumarinyl) maleimide. An application to the proteins separated by SDS-polyacrylamide gel electrophoresis.

K. Yamamoto, Y. Kanaoka, S. Takamitsu, 1977, Analytical biochemistry.

Fluorescent thiol reagents. VI. N-(1-Anilinonaphthyl-4)maleimide; a fluorescent hydrophobic probe directed to thiol groups in protein.

M. Machida, Y. Kanaoka, T. Sekine, 1973, Biochimica et biophysica acta.

SYNTHESES OF THIENO(2,3-C)-, PYRROLO(2,3-C)-, AND INDOLO(2,3-C)DIAZANAPHTHALENES BY PHOTOCYCLIZATION OF ACYLAMINOPYRIDINES

Y. Hatanaka, M. Machida, Y. Kanaoka, 1977 .

PHOTO-FRIES REARRANGEMENT OF HETEROAROMATIC ACID PHENYL ESTERS

Y. Hatanaka, Y. Kanaoka, 1974 .

Amino acids and peptides. II. Cyclodehydration of some tryptophan-dipeptides and their derivatives with polyphosphate ester.

Y. Kanaoka, O. Yonemitsu, E. Sato, 1968, Tetrahedron.

N-(7-Dimethylamino-4-methyl-coumarinyl) maleimides (DACM) : Novel Fluorescent Thiol Reagents

M. Machida, Y. Kanaoka, M. Machida, 1975 .

Fluorescent thiol reagents. V. Microfluorometry of thiol compounds with a fluorescent-labeled maleimide.

M. Machida, Y. Kanaoka, T. Sekine, 1972, Analytical biochemistry.

Synthesis and Metabolism of 6-Hydroxycatecholamines*

J. Daly, B. Witkop, Y. Kanaoka, 1965 .

Photochemistry of Conjugated Nitrogen-Thiocarbonyl Systems. VII. : Photoaddition of Quinoline-, Isoquinoline- and Phthalazine-Thione Systems to Olefins

Y. Kanaoka, E. Sato, Y. Ikeda, 1990 .

Photochemistry of the N-acyllactam and acyclic thioimide systems. Competition between Paterno-Büchi type and Norrish type 1 reactions

M. Machida, Y. Kanaoka, K. Oda, 1988 .

Photochemistry of the nitrogen-thiocarbonyl systems. 2. Photochemistry of the thioimide systems: imide-thietanes

M. Machida, Y. Kanaoka, K. Oda, 1985 .

A synthesis of 1, 2-tetramethylene-3, 4-dihydro-beta-carboline.

Y. Kanaoka, M. Terashima, S. Sugasawa, 1956, Pharmaceutical bulletin.

Photochemistry of Conjugated Nitrogen-Thiocarbonyl Systems. Part 7. Photoaddition of Quinoline-, Isoquinoline-, and Phthalazinethione Systems to Olefins.

Y. Kanaoka, E. Sato, Y. Ikeda, 1991 .

Photochemistry of Conjugated Nitrogen-Thiocarbonyl Systems. V. : Two-Fold Photoaddition of Vinyl Ethers to Aza-Aromatic Thiones(Organic,Chemical)

Y. Kanaoka, E. Sato, Y. Ikeda, 1987 .

The Norrish type II reaction of thiophthalimides having a benzylic hydrogen in an N-alkyl side chain.

M. Machida, Y. Kanaoka, K. Oda, 1989 .

Photochemistry of the Nitrogen-Thiocarbonyl Systems. Part 12. Photochemistry of the N-Acyllactam and Acyclic Thioimide Systems. Competition Between Paterno-Buechi Type and Norrish Type 1 Reactions.

M. Machida, Y. Kanaoka, K. Oda, 1989 .

Photoaddition of Olefins to Quinolin-, Isoquinolin-, and Phthalazin-thione Systems

Y. Kanaoka, E. Sato, Y. Ikeda, 1987 .

The norrish type II reaction of the cyclic thioimides with a benzylic hydrogen

M. Machida, Y. Kanaoka, K. Oda, 1985 .

Synthesis of heteroarylquinolines by the photolysis of 2-, 3-, and 4-iodoquinolines

Y. Kanaoka, K. Seki, K. Ohkura, 1990 .

FLUORESCENT THIOL REAGENTS. XII. A NOVEL FLUORESCENT THIOL REAGENT- SYNTHESES AND ELECTRONIC SPECTRA OF N-(7-DIMETHYLAMINO-4-METHYL-3-COUMARINYL)MALEIMIDE (DACM-3) AND THE RELATED COMPOUNDS

Tetsuo Takahashi, M. Machida, Y. Kanaoka, 1977 .

A Novel Fluorescent Thiol Reagent : Syntheses and Electronic Spectra of N-(7-Dimethylamino-4-methyl-3-coumarinyl)-maleimide (DACM-3) and the Related Compounds

Tetsuo Takahashi, M. Machida, Y. Kanaoka, 1977 .

Photo-Arylation. VII. : Photoreaction of 2-Halopyridine with Indole

Y. Kanaoka, K. Seki, K. Ohkura, 1988 .

Photochemistry of the phthalimide system. III. Photocyclization with favored δ-hydrogen abstraction☆

Y. Kanaoka, H. Nakai, Yasuhiko Sato, 1973 .

Fluorescent thiol reagents. X. Fluorimetric estimation of the reactivity of thiols; examples in small molecular compounds, Taka-amylase A and myosin A.

M. Machida, Y. Kanaoka, T. Sekine, 1974, Biochimica et biophysica acta.

STUDIES ON PROTEIN-SULFHYDRYL REAGENTS. I. SYNTHESIS OF BENZIMIDAZOLE DERIVATIVES OF MALEIMIDE; FLUORESCENT LABELING OF MALEIMIDE.

M. Machida, Y. Kanaoka, Y. Ban, 1964, Chemical and pharmaceutical bulletin.

Photochemistry of the phthalimide system. V photocyclization of the phthalimides with a sulfide chain: synthesis of aza-cyclols by δ, ε, and ς hydrogen abstraction

Y. Kanaoka, H. Nakai, T. Mizoguchi, 1973 .

Photorearrangement of N, N-Diacetyl Derivatives of Aniline and Naphthylamines

Y. Kanaoka, K. Itoh, K. Kôyama, 1973 .

A new fluorogenic substrate for aminopeptidase.

H. Nakayama, Y. Kanaoka, T. Takahashi, 1977, Chemical & pharmaceutical bulletin.

Fluorogenic bimane substrates with dabsyl group for endopeptidases; chymotrypsin, collagenase and thermolysin.

Y. Kanaoka, E. Sato, H. Hattori, 1991, Journal of pharmacobio-dynamics.

Photocyclizations of pharmacodynamic amines. II. X-ray analysis of a noncentrosymmetric tetracyclic indole.

I. Karle, B. Witkop, Y. Kanaoka, 1968, Journal of the American Chemical Society.

Specific spin-labeling at trypsin active site. Application of 'inverse substrate' to the structural analysis of the active site.

Y. Kanaoka, K. Tanizawa, T. Fujioka, 1980, Biochimica et biophysica acta.

Design of biospecific compounds which simulate enzyme-substrate interaction

Y. Kanaoka, K. Tanizawa, 1986 .

Proteolytic enzymes. 7. "Inverse substrates" for trypsin. Efficient enzymic hydrolysis of certain esters with a cationic center in the leaving group

Y. Kanaoka, K. Tanizawa, Y. Kasaba, 1977 .

Chemical evidence showing involvement of sulfhydryl groups in protein synthesis with E. coli system.

A. Watanabe, M. Machida, Y. Kanaoka, 1971, Biochemical and biophysical research communications.

Fluorescence Thiol Reagents : Syntheses and Properties of N-Acridinylmaleimides and Their Derivatives

Tetsuo Takahashi, M. Machida, Y. Kanaoka, 1978 .

Photoisomerization of 4-t-Butyl-2-piridones and Chemical Properties of the Resulting 2-Azabicyclo[2.2.0]hex-5-en-3-one and the Hexan-3-one Systems

Y. Kanaoka, H. Okajima, E. Sato, 1987 .

Photochemistry of Conjugated Nitrogen‐Carbonyl Systems. Part 4. Photoisomerization of 4‐tert‐Butyl‐2‐pyridones and Chemical Properties of the Resulting 2‐Azabicyclo(2.2.0)hex‐5‐en‐3‐one and the Hexan‐3‐one Systems.

Y. Kanaoka, H. Okajima, E. Sato, 1987 .

Efficient Synthetic Method for Ethyl (+)‐(2S,3S)‐3‐((S)‐3‐Methyl‐1‐(3‐ methylbutylcarbamoyl)butylcarbamoyl)‐2‐oxiranecarboxylate (EST), a New Inhibitor of Cysteine Proteinases.

M. Murata, Y. Kanaoka, M. Tamai, 1987 .

Photosensitized Oxyganetion of 2-Pyridones

Y. Kanaoka, E. Sato, Y. Ikeda, 1987 .

Photochemistry of the Conjugated Nitrogen-Carbonyl Systems. Part 2. Photosensitized Oxygenation of 2-Pyridones.

Y. Kanaoka, E. Sato, Y. Ikeda, 1987 .

3H-Indoles. IV. Photo-and Peroxide-induced Oxygenation of 2-Ethyl-3H-indoles

Y. Kanaoka, O. Yonemitsu, K. Miyashita, 1970 .

3H-indoles--II. Synthesis of 3-alkyl-3H indoles by the alkylation of 2,3-disubstituted indoles with polyphosphate ester and some reactions of the 3H-indole system.

Y. Kanaoka, O. Yonemitsu, K. Miyashita, 1969, Tetrahedron.

Polyphosphate esters as a synthetic agent. 3. Amide and peptide syntheses.

M. Machida, Y. Kanaoka, Y. Ban, 1965, Chemical & pharmaceutical bulletin.

New water-soluble fluorogenic amine. 7-Aminocoumarin-4-methanesulfonic acid (ACMS) and related substrates for proteinases.

Y. Kanaoka, A. Matsuhisa, E. Sato, 1988, Chemical & pharmaceutical bulletin.

New fluorogenic substrates for subtilisin.

H. Nakayama, Y. Kanaoka, K. Tanizawa, 1985, Chemical & pharmaceutical bulletin.

Proteolytic enzymes. V. Further application of p-nitrophenyl p-amidinobenzoate as a titrant of trypsin.

Y. Kanaoka, T. Ikenaka, K. Tanizawa, 1970, Chemical & pharmaceutical bulletin.

Efficient tryptic hydrolysis of aryl esters with a cationic center in the leaving group. Further characterization of "inverse substrates".

Y. Kanaoka, K. Tanizawa, M. Nozawa, 1980 .

"Inverse substrates" for trypsin. Efficient enzymatic hydrolysis of certain esters with a cationic center in the leaving group1.

Y. Kanaoka, K. Tanizawa, Y. Kasaba, 1977, Journal of the American Chemical Society.

Photoreactions of thiobarbiturates with olefins; Thietane formation by intermolecular photocycloaddition.

M. Machida, Y. Kanaoka, H. Takechi, 1989 .

Photochemistry of the Nitrogen-Thiocarbonyl System. Part 14. Photoreactions of Thiobarbiturates with Olefines. Thietane Formation by Intermolecular Photocycloaddition.

M. Machida, Y. Kanaoka, H. Takechi, 1990 .

Photochemistry of the Nitrogen-Thiocarbonyl-Systems. Part 13. The Norrish Type II Reaction of Thiophthalimides Having a Benzylic Hydrogen in an N-Alkyl Side Chain.

M. Machida, Y. Kanaoka, K. Oda, 1989 .

Intramolecular Photocyclization of 3-Substituted Alicyclic Dithioimides: Facile Synthesis of 2-Azabicycloalkanes via the Norrish Type II Process.

M. Machida, Y. Kanaoka, K. Oda, 1987 .

Intermolecular Photoreactions of Phthalimide-Alkene Systems. Regio-and Stereoselective Oxetane Formation from N -Methylphthalimide and N -Acetylindole Derivatives

M. Machida, Y. Kanaoka, H. Takechi, 1988 .

Structural characterization of the dihydropyridine receptor-linked calcium channel from porcine heart.

Y. Hatanaka, H. Nakayama, A. Kuniyasu, 1992, Journal of biochemistry.

Photochemistry of the Phthalimide System, 39. Photoinduced Reactions, 84. Photochemistry of ω‐Phthalimidoalkanoic Acid Derivatives Syntheses of Multicyclic Fused Hydropyrazines and 1,4‐Diazepines

M. Machida, Y. Kanaoka, H. Takechi, 1986 .

Synthesis of diazipine and [3H]diazipine: novel dihydropyridines as photoaffinity probes of calcium channels.

H. Nakayama, A. Kuniyasu, Y. Kanaoka, 1991, Chemical and pharmaceutical bulletin.

Novel fluorogenic substrates for phosphodiesterase I.

M. Yoshikawa, Y. Kanaoka, E. Sato, 1990, Chemical & pharmaceutical bulletin.

New fluorogenic substrates containing bimane system for ribonuclease T1.

Y. Kanaoka, E. Sato, S. Itoh, 1991, Journal of Pharmacobio-Dynamics.

New fluorogenic substrates for microdetermination of cathepsin C.

K. Matsuda, Y. Kanaoka, E. Sato, 1990, Chemical & pharmaceutical bulletin.

New fluorogenic substrates for microdetermination of carboxypeptidase A.

Y. Kanaoka, E. Sato, 1988, Chemical & pharmaceutical bulletin.

Novel fluorogenic substrates containing bimane system for microdetermination of angiotensin I converting enzyme.

S. Nishikawa, Y. Kanaoka, E. Sato, 1989, Chemical & pharmaceutical bulletin.

Predominant transesterification reaction catalyzed by immobilized trypsin.

Y. Kanaoka, K. Tanizawa, 1984, Chemical & pharmaceutical bulletin.

Modification of carboxyl groups in the binding sites of trypsin with the Meerwein reagent.

H. Nakayama, Y. Kanaoka, K. Tanizawa, 1970, Biochemical and biophysical research communications.

Immobilized chymotrypsin by means of Schiff base copper(II) chelate.

Y. Kanaoka, K. Moriya, K. Tanizawa, 1989, Biochemical and biophysical research communications.

Oxidation of Kynuramine Derivatives by Monoamine Oxidase and the Enzymatic Conversion of Dihydronorkynuramine to Indigo

H. Weissbach, B. Witkop, Y. Kanaoka, 1961 .

Photocyclization of N-Aminoalkylphthalamides. Syntheses of Multicyclic Fused Hexahydropyrazines and Hexahydro-1,4-diazepines

M. Machida, Y. Kanaoka, H. Takechi, 1980 .

PHOTOCHEMISTRY OF THE PHTHALIMIDE SYSTEM. PART 19. PHOTOCYCLIZATION OF N-AMINOALKYLPHTHALIMIDES. SYNTHESES OF MULTICYCLIC FUSED HEXAHYDROPYRAZINES AND HEXAHYDRO-1,4-DIAZEPINES

M. Machida, Y. Kanaoka, H. Takechi, 1981 .

Photoreactions of Benzoylaminopyridines

Y. Kanaoka, K. Itoh, 1974 .

Synthesis of Heterocyclic-Condensed Quinolones by Oxidative Photochemical Cyclization of Amide systems1

Y. Kanaoka, K. Itoh, 1972 .

Schiff base copper(II) chelate as a tool for intermolecular cross-linking and immobilization of protein.

Y. Kanaoka, K. Moriya, K. Tanizawa, 1989, Biochemical and biophysical research communications.

Comparison of Streptomyces griseus and bovine trypsin by active site analysis using fluorescent acyl groups.

Y. Kanaoka, K. Tanizawa, M. Nakano, 1987, Biochimica et biophysica acta.

Anhydrosubtilisin‐catalyzed peptide synthesis

Y. Kanaoka, K. Tanizawa, A. Sugimura, 1992, FEBS letters.

Proteolytic Enzymes

Y. Kanaoka, K. Tanizawa, S. Ishii, 2010 .