D. Castven

发表

Activation of a Ductal-to-Endocrine Transdifferentiation Transcriptional Program in the Pancreatic Cancer Cell Line PANC-1 Is Controlled by RAC1 and RAC1b through Antagonistic Regulation of Stemness Factors

H. Lehnert, G. Riemekasten, J. Marquardt, 2021, Cancers.

Ginkgo biloba induces different gene expression signatures and oncogenic pathways in malignant and non-malignant cells of the liver

P. Galle, S. Heilmann-Heimbach, S. Strand, 2018, PloS one.

Cluster of differentiation 44 promotes osteosarcoma progression in mice lacking the tumor suppressor Merlin

B. Bartosch, M. Giovannini, P. Herrlich, 2020, International journal of cancer.

Markers of cell death predict therapy response in patients with cirrhosis and hepatorenal syndrome

C. Labenz, M. Kirstein, T. Austgen, 2022, United European gastroenterology journal.

Colorectal Cancer Progression Is Potently Reduced by a Glucose-Free, High-Protein Diet: Comparison to Anti-EGFR Therapy

C. Sina, J. Marquardt, M. Ragab, 2021, bioRxiv.

Contribution of the Cancer Stem Cell Phenotype to Hepatocellular Carcinoma Resistance

J. Marquardt, D. Castven, C. Czauderna, 2017 .

Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer.

S. Thorgeirsson, P. Galle, V. Factor, 2015, Journal of hepatology.

Severe metabolic alterations in liver cancer lead to ERK pathway activation and drug resistance

Z. Nwosu, N. Battello, W. Piorońska, 2020, EBioMedicine.

Translational Considerations to Improve Response and Overcome Therapy Resistance in Immunotherapy for Hepatocellular Carcinoma

P. Galle, J. Marquardt, D. Castven, 2020, Cancers.

Establishment and Molecular Characterization of Two Patient-Derived Pancreatic Ductal Adenocarcinoma Cell Lines as Preclinical Models for Treatment Response

M. Spielmann, M. Drenckhan, A. Künstner, 2023, Cells.

The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC-1—A Useful Model to Study Clonal Heterogeneity and EMT Subtype Shifting

H. Oster, J. Marquardt, Rüdiger Braun, 2022, Cancers.

Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis

S. Thorgeirsson, H. Binder, M. Odenthal, 2021, JCI insight.

Application of patient‐derived liver cancer cells for phenotypic characterization and therapeutic target identification

S. Thorgeirsson, P. Galle, S. Heilmann-Heimbach, 2018, International journal of cancer.

Context-Dependent Role of NF-κB Signaling in Primary Liver Cancer—from Tumor Development to Therapeutic Implications

J. Marquardt, F. Mahn, D. Castven, 2019, Cancers.

Adverse genomic alterations and stemness features are induced by field cancerization in the microenvironment of hepatocellular carcinomas

S. Thorgeirsson, P. Galle, S. Heilmann-Heimbach, 2017, Oncotarget.

Acquired Resistance to Antiangiogenic Therapies in Hepatocellular Carcinoma Is Mediated by Yes‐Associated Protein 1 Activation and Transient Expansion of Stem‐Like Cancer Cells

S. Thorgeirsson, P. Galle, S. Heilmann-Heimbach, 2021, Hepatology communications.

Dynamics and predicted drug response of a gene network linking dedifferentiation with beta-catenin dysfunction in hepatocellular carcinoma.

J. Zucman‐Rossi, E. Hanert, G. Couchy, 2019, Journal of hepatology.

Application of patient derived liver cancer cell lines for phenotypic characterization and therapeutic target identification

S. Thorgeirsson, P. Galle, S. Heilmann-Heimbach, 2018, Zeitschrift für Gastroenterologie.

Dynamics and predicted drug response of a gene network linking dedifferentiation with β-catenin dysfunction in hepatocellular carcinoma

J. Zucman‐Rossi, E. Hanert, G. Couchy, 2018, bioRxiv.

Chromosome 8p engineering reveals increased metastatic potential targetable by patient-specific synthetic lethality in liver cancer

B. Goeppert, S. Roessler, D. Castven, 2023, Science advances.