C. Loncle

发表

Genetic inactivation of Nupr1 acts as a dominant suppressor event in a two-hit model of pancreatic carcinogenesis

J. Iovanna, N. Dusetti, C. Cano, 2013, Gut.

p8 Expression controls pancreatic cancer cell migration, invasion, adhesion, and tumorigenesis

J. Dagorn, J. Iovanna, C. Cano, 2011, Journal of cellular physiology.

Deciphering the cellular source of tumor relapse identifies CD44 as a major therapeutic target in pancreatic adenocarcinoma

J. Iovanna, N. Dusetti, S. Garcia, 2015, Oncotarget.

IL17 Functions through the Novel REG3β-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer.

P. Dubus, J. Iovanna, G. Lomberk, 2015, Cancer research.

Pivotal Role of the Chromatin Protein Nupr1 in Kras-Induced Senescence and Transformation

J. Iovanna, G. Lomberk, R. Urrutia, 2015, Scientific Reports.

Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma

R. Tomasini, J. Iovanna, G. Bidaut, 2015, Proceedings of the National Academy of Sciences.

Gene expression profiling of patient‐derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts

J. Qi, J. Bradner, J. Iovanna, 2017, EMBO molecular medicine.

IER 3 supports KRASG 12 D-dependent pancreatic cancer development by sustaining ERK 1 / 2 phosphorylation

R. Tomasini, J. Iovanna, G. Lomberk, 2022 .

Synthesis and antifungal activity of cholesterol-hydrazone derivatives.

J. Brunel, M. Dherbomez, C. Loncle, 2004, European journal of medicinal chemistry.

Squalamine: An Appropriate Strategy against the Emergence of Multidrug Resistant Gram-Negative Bacteria?

J. Fantini, J. Pagés, J. Brunel, 2008, PloS one.

Synthesis, Physical Characterization, Antibacterial and Antifungal Activities of 2-((E)-1-(2-((E)-1-(2-Hydroxyphenyl)ethylideneamino) phenylamino) ethyl) phenol

B. Trzaskowski, A. Jalbout, J. Brunel, 2006 .

New stereoselective titanium reductive amination synthesis of 3-amino and polyaminosterol derivatives possessing antimicrobial activities.

J. Brunel, C. Loncle, N. Vidal, 2008, European journal of medicinal chemistry.

Synthesis and antifungal activity of oxygenated cholesterol derivatives

J. Brunel, M. Dherbomez, C. Loncle, 2005, Steroids.

Efficient preparation of secondary aminoalcohols through a Ti(IV) reductive amination procedure. Application to the synthesis and antibacterial evaluation of new 3β-N-[hydroxyalkyl]aminosteroid derivatives

J. Brunel, C. Loncle, Y. Letourneux, 2008 .

Dendrimeric nanosystem consistently circumvents heterogeneous drug response and resistance in pancreatic cancer

Xing-jie Liang, E. Laurini, D. Marson, 2021, Exploration.

Further Characterization of HDAC and SIRT Gene Expression Patterns in Pancreatic Cancer and Their Relation to Disease Outcome

J. Iovanna, D. Lombardo, B. Sastre, 2014, PloS one.

A subgroup of pancreatic adenocarcinoma is sensitive to the 5-aza-dC DNA methyltransferase inhibitor

J. Iovanna, N. Dusetti, P. Viens, 2014, Oncotarget.

Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma

R. Tomasini, J. Iovanna, N. Dusetti, 2013, Proceedings of the National Academy of Sciences.

Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer

G. Kroemer, J. Iovanna, C. Cano, 2012, EMBO molecular medicine.

Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts

J. Iovanna, N. Dusetti, R. Urrutia, 2017, Cell reports.

Cancer-associated fibroblast-derived annexin A6+ extracellular vesicles support pancreatic cancer aggressiveness.

S. Granjeaud, C. Brun, A. Sergé, 2016, The Journal of clinical investigation.

IER3 supports KRASG12D-dependent pancreatic cancer development by sustaining ERK1/2 phosphorylation.

R. Tomasini, J. Iovanna, G. Lomberk, 2014, The Journal of clinical investigation.

The pancreatitis-associated protein VMP1, a key regulator of inducible autophagy, promotes KrasG12D-mediated pancreatic cancer initiation

J. Iovanna, N. Dusetti, G. Lomberk, 2016, Cell Death and Disease.

A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT

J. Iovanna, N. Dusetti, S. Garcia, 2016, Oncotarget.

Transcriptomic analysis predicts survival and sensitivity to anticancer drugs of patients with a pancreatic adenocarcinoma.

J. Iovanna, N. Dusetti, P. Viens, 2015, The American journal of pathology.

BTN3A is a prognosis marker and a promising target for Vγ9Vδ2 T cells based-immunotherapy in pancreatic ductal adenocarcinoma (PDAC)

D. Olive, J. Dagorn, J. Iovanna, 2018, Oncoimmunology.

Synthesis of new 7-aminosterol squalamine analogues with high antimicrobial activities through a stereoselective titanium reductive amination reaction

J. Brunel, C. Loncle, Y. Letourneux, 2007 .

Squalamine: a polyvalent drug of the future?

J. Brunel, C. Loncle, N. Vidal, 2005, Current cancer drug targets.

Antimicrobial Activities of 3-Amino- and Polyaminosterol Analogues of Squalamine and Trodusquemine

M. Laget, C. Loncle, N. Vidal, 2008 .

New 3-Aminosteroid Derivatives as a New Family of Topical Antibacterial Agents Active against Methicillin-Resistant Staphylococcus aureus (MRSA)

J. Brunel, M. Laget, C. Loncle, 2008 .

p8 Expression controls pancreatic cancer cell migration, invasion, adhesion, and tumorigenesis

J. Dagorn, J. Iovanna, C. Cano, 2011, Journal of cellular physiology.