G. Andrei

发表

Synthesis and anti-HIV-1 and anti-HCMV activity of 1-substituted 3-(3,5-dimethylbenzyl)uracil derivatives.

E. De Clercq, C. Pannecouque, J. Balzarini, 2006, Chemical & pharmaceutical bulletin.

The large tumor antigen: a "Swiss Army knife" protein possessing the functions required for the polyomavirus life cycle.

G. Andrei, R. Snoeck, D. Topalis, 2013, Antiviral research.

The novel phosphoramidate derivatives of NSAID 3-hydroxypropylamides: synthesis, cytostatic and antiviral activity evaluations.

E. De Clercq, K. Pavelić, M. Kralj, 2009, European journal of medicinal chemistry.

Inhibitory effect of selected antiviral compounds on arenavirus replication in vitro.

E. De Clercq, E. Clercq, G. Andrei, 1990, Antiviral research.

Activities of Different Classes of Acyclic Nucleoside Phosphonates against BK Virus in Primary Human Renal Cells

R. Snoeck, D. Topalis, G. Andrei, 2011, Antimicrobial Agents and Chemotherapy.

Dual infection with polyomavirus BK and acyclovir‐resistant herpes simplex virus successfully treated with cidofovir in a bone marrow transplant recipient

E. De Clercq, G. Opdenakker, R. Snoeck, 2007, Transplant infectious disease : an official journal of the Transplantation Society.

SURVEY AND SUMMARY Distribution and effects of amino acid changes in drug-resistant (cid:2) and (cid:3) herpesviruses DNA polymerase

R. Snoeck, D. Topalis, G. Andrei, 2016 .

Differential antiviral activity of derivatized dextrans.

S. Ikeda, J. Neyts, D. Letourneur, 1995, Biochemical pharmacology.

Activities of various compounds against murine and primate polyomaviruses

E. De Clercq, E. Clercq, G. Andrei, 1997, Antimicrobial agents and chemotherapy.

Antivaccinia Activities of Acyclic Nucleoside Phosphonate Derivatives in Epithelial Cells and Organotypic Cultures

E. De Clercq, J. J. van den Oord, G. Andrei, 2002, Antimicrobial Agents and Chemotherapy.

Resistance of herpes simplex virus type 1 against different phosphonylmethoxyalkyl derivatives of purines and pyrimidines due to specific mutations in the viral DNA polymerase gene.

R. Esnouf, E. De Clercq, G. Opdenakker, 2000, The Journal of general virology.

Human Brain Tumour Cell Lines as Cell Substrate to Demonstrate Sensitivity/Resistance of Herpes Simplex Virus Types 1 and 2 to Nucleoside Analogues

E. De Clercq, R. Snoeck, G. Andrei, 1994 .

Comparative activity of various compounds against clinical strains of herpes simplex virus

E. Clercq, G. Andrei, R. Snoeck, 1992, European Journal of Clinical Microbiology and Infectious Diseases.

Antiviral activity of a sulphated polysaccharide from the red seaweed Nothogenia fastigiata.

E. Damonte, S. Ikeda, J. Neyts, 1994, Biochemical pharmacology.

Molecular approaches for the treatment of hemorrhagic fever virus infections.

E. De Clercq, G. Andrei, G. Andrei, 1993, Antiviral research.

New Polyacetal Polysulphate Active against Human Immunodeficiency Virus and other Enveloped Viruses

A. Van Schepdael, E. De Clercq, R. Pauwels, 1992 .

In vitro Sensitivity of Kaposi's Sarcoma Cells to Various Chemotherapeutic Agents Including Acyclic Nucleoside Phosphonates

E. De Clercq, G. Andrei, R. Snoeck, 1999, Antiviral chemistry & chemotherapy.

Synthesis and antiviral activity evaluation of some new aminoadamantane derivatives. 2.

E. De Clercq, J. Neyts, J. Balzarini, 1996, Journal of medicinal chemistry.

Antiviral activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide and related compounds

E. De Clercq, N. Minakawa, A. Matsuda, 1991, Antimicrobial Agents and Chemotherapy.

Structure-antiviral activity relationship in the series of pyrimidine and purine N-[2-(2-phosphonomethoxy)ethyl] nucleotide analogues. 1. Derivatives substituted at the carbon atoms of the base.

E. De Clercq, J. Balzarini, G. Andrei, 1999, Journal of medicinal chemistry.

Antiproliferative effects of acyclic nucleoside phosphonates on human papillomavirus (HPV)-harboring cell lines compared with HPV-negative cell lines.

P. Delvenne, E. De Clercq, J. Piette, 1998, Oncology research.

Broad-Spectrum Antiviral Activity and Mechanism of Antiviral Action of the Fluoroquinolone Derivative K-12

E. De Clercq, C. Pannecouque, A. Vandamme, 1998, Antiviral chemistry & chemotherapy.

Synthesis and antiviral properties of (+/-)-5'-noraristeromycin and related purine carbocyclic nucleosides. A new lead for anti-human cytomegalovirus agent design.

E. De Clercq, M. Hosoya, J. Balzarini, 1992, Journal of medicinal chemistry.

Synthesis and Antiviral Activity of 2 and 3-Substituted Imidazo[1,2-a]pyrimidine

F. Fauvelle, E. Clercq, R. Snoeck, 1995 .

Potent and selective inhibition of varicella-zoster virus (VZV) by nucleoside analogues with an unusual bicyclic base.

E. De Clercq, A. Brancale, J. Balzarini, 1999, Journal of medicinal chemistry.

Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents.

E. De Clercq, J. Balzarini, M. Witvrouw, 1996, Journal of medicinal chemistry.

Imidazothiadiazine dioxides: synthesis and antiviral activity.

E. De Clercq, J. Balzarini, R. Snoeck, 1999, Bioorganic & medicinal chemistry.

New neplanocin analogues. 6. Synthesis and potent antiviral activity of 6'-homoneplanocin A1.

E. De Clercq, S. Shuto, R. Snoeck, 1996, Journal of medicinal chemistry.

An epimer of 5'-noraristeromycin and its antiviral properties.

E. De Clercq, S. Ikeda, J. Balzarini, 1994, Journal of medicinal chemistry.

New neplanocin analogues. 7. Synthesis and antiviral activity of 2-halo derivatives of neplanocin A.

E. De Clercq, S. Shuto, A. Matsuda, 1996, Journal of medicinal chemistry.

New neplanocin analogues. 1. Synthesis of 6'-modified neplanocin A derivatives as broad-spectrum antiviral agents.

E. De Clercq, S. Shuto, M. Hosoya, 1992, Journal of medicinal chemistry.

The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine.

E. De Clercq, P. Herdewijn, R. Snoeck, 2000, Journal of medicinal chemistry.

Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymerase

G. Andrei, R. Snoeck, D. Topalis, 2016, Nucleic acids research.

Epithelial raft cultures for investigations of virus growth, pathogenesis and efficacy of antiviral agents.

J. J. van den Oord, G. Andrei, R. Snoeck, 2010, Antiviral research.

Activity of a Sulfated Polysaccharide Extracted from the Red Seaweed Aghardhiella Tenera against Human Immunodeficiency Virus and Other Enveloped Viruses

E. De Clercq, R. Pauwels, S. Ikeda, 1994 .

Sulphated Polymers are Potent and Selective Inhibitors of Various Enveloped Viruses, Including Herpes Simplex Virus, Cytomegalovirus, Vesicular Stomatitis Virus, Respiratory Syncytial Virus, and Toga-, Arena- and Retroviruses

E. De Clercq, R. Pauwels, M. Hosoya, 1990 .

Insights into the mechanism of action of cidofovir and other acyclic nucleoside phosphonates against polyoma- and papillomaviruses and non-viral induced neoplasia.

G. Andrei, R. Snoeck, D. Topalis, 2015, Antiviral research.

Comparative activity of selected antiviral compounds against clinical isolates of human cytomegalovirus

E. Clercq, D. Schols, R. Snoeck, 1991, European Journal of Clinical Microbiology and Infectious Diseases.

In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?

E. De Clercq, G. Andrei, R. Snoeck, 2004, Antiviral research.

Specific therapies for human papilloma virus infections.

E. De Clercq, G. Andrei, R. Snoeck, 1998, Current opinion in infectious diseases.

Comparative activity of selected antiviral compounds against clinical isolates of varicella-zoster virus

E. Clercq, G. Andrei, R. Snoeck, 1995, European Journal of Clinical Microbiology and Infectious Diseases.

New neplanocin analogues. VIII. Synthesis and biological activity of 6'-C-ethyl, -ethenyl, and -ethynyl derivatives of neplanocin A.

E. De Clercq, S. Shuto, A. Matsuda, 1997, Chemical & pharmaceutical bulletin.

Synthesis, biological evaluation, and structure analysis of a series of new 1,5-anhydrohexitol nucleosides.

E. De Clercq, J. Rozenski, J. Balzarini, 1995, Journal of medicinal chemistry.

Antiviral enantiomeric preference for 5'-noraristeromycin.

E. De Clercq, S. Ikeda, J. Balzarini, 1994, Journal of medicinal chemistry.

Novel carbocyclic nucleosides containing a cyclobutyl ring. Guanosine and adenosine analogues.

E. De Clercq, J. Balzarini, R. Snoeck, 1998, Nucleosides and Nucleotides.

Activity and Mechanism of Action of HDVD, a Novel Pyrimidine Nucleoside Derivative with High Levels of Selectivity and Potency against Gammaherpesviruses

J. J. van den Oord, Y. Cheng, C. K. Chu, 2013, Journal of Virology.

Advances in the treatment of varicella-zoster virus infections.

G. Andrei, R. Snoeck, G. Andrei, 2013, Advances in pharmacology.

3-deaza- and 7-deaza-5'-noraristeromycin and their antiviral properties.

E. De Clercq, S. Ikeda, J. Balzarini, 1995, Journal of medicinal chemistry.

Synthesis and antiviral activities of 8-alkynyl-, 8-alkenyl-, and 8-alkyl-2'-deoxyadenosine analogues.

E. De Clercq, S. Ikeda, R. Snoeck, 1994, Journal of medicinal chemistry.

Synthesis and Antiviral Activity of 1,3-Disubstituted Uracils against HIV-1 and HCMV

E. De Clercq, C. Pannecouque, J. Balzarini, 2003, Antiviral chemistry & chemotherapy.

Thienothiadiazine 2,2-Dioxide Acyclonucleosides: Synthesis and Antiviral Activity

E. De Clercq, J. Balzarini, R. Snoeck, 2000, Antiviral chemistry & chemotherapy.

Discovery of type II (covalent) inactivation of S-adenosyl-L-homocysteine hydrolase involving its "hydrolytic activity": synthesis and evaluation of dihalohomovinyl nucleoside analogues derived from adenosine.

E. De Clercq, R. Borchardt, J. Balzarini, 1998, Journal of medicinal chemistry.

3-Benzamido, ureido and thioureidoimidazo[1,2-a]pyridine derivatives as potential antiviral agents.

E. De Clercq, C. Pannecouque, A. Kherbeche, 2001, Chemical & pharmaceutical bulletin.

Synthesis of imidazo[1,2-a]pyridines as antiviral agents.

E. De Clercq, J. Balzarini, M. Witvrouw, 1998, Journal of medicinal chemistry.

Influence of 2-substituent on the activity of imidazo[1,2-a] pyridine derivatives against human cytomegalovirus.

E. De Clercq, J. Balzarini, R. Snoeck, 2002, Bioorganic & medicinal chemistry.

Synthesis and antiviral activity of 6-chloropurine arabinoside and its 2'-deoxy-2'-fluoro derivative.

E. De Clercq, M. Witvrouw, Y. Takahashi, 1996, Chemical & pharmaceutical bulletin.

Susceptibilities of several drug-resistant herpes simplex virus type 1 strains to alternative antiviral compounds

E. De Clercq, R. Snoeck, G. Andrei, 1995, Antimicrobial agents and chemotherapy.

Synthesis and biological evaluation of 1,2-disubstituted carbonucleosides of 6-substituted purine and 8-azapurine.

E Uriarte, L. Santana, E. Uriarte, 1999, Nucleosides & nucleotides.

Synthesis and Biological Activity of Some 2-Aminopurine Carbonucleosides

L. Santana, E. Uriarte, M. Teijeira, 1997 .

Synthesis and antiviral activity of carbocyclic oxetanocin analogues (C-OXT-A, C-OXT-G) and related compounds. II.

E. De Clercq, M. Hosoya, J. Balzarini, 1993, Chemical & pharmaceutical bulletin.

Human cytomegalovirus (HCMV) strains selected under selective pressure of phosphonoformate (PFA) are resistant for both PFA and phosphonylmethoxyethyl (PME) derivatives in vitro

E. Clercq, R. Snoeck, G. Andrei, 1995 .

Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro

E. Clercq, R. Snoeck, G. Andrei, 1996, European Journal of Clinical Microbiology and Infectious Diseases.

Dipyridamole Potentiates the Activity of Various Acyclic Nucleoside Phosphonates against Varicella-Zoster Virus, Herpes Simplex Virus and Human Cytomegalovirus

E. De Clercq, J. Balzarini, G. Andrei, 1994 .

Synthesis and Antiviral Activities of 8-Alkynyl-, 8-Alkenyl-, and 8- Alkyl-2′-deoxyadenosine Analogues.

S. Ikeda, E. Clercq, R. Snoeck, 1994 .

Monitoring drug resistance for herpesviruses.

E. De Clercq, G. Opdenakker, R. Snoeck, 2000, Methods in molecular medicine.

Synthesis of 2′‐Aminomethyl Derivatives of N‐(2‐(Phosphonomethoxy) ethyl) Nucleotide Analogues as Potential Antiviral Agents.

J. Balzarini, E. Clercq, R. Snoeck, 1996 .

Antiviral Activity of 3-(3,5-Dimethylbenzyl)Uracil Derivatives Against Hiv-1 and HCMV

E. De Clercq, C. Pannecouque, J. Balzarini, 2007, Nucleosides, nucleotides & nucleic acids.

Bicyclic anti-VZV nucleosides: Thieno analogues retain full antiviral activity.

P. Savy, E. De Clercq, A. Brancale, 2001, Bioorganic & medicinal chemistry letters.

Novel potential agents for human cytomegalovirus infection: synthesis and antiviral activity evaluation of benzothiadiazine dioxide acyclonucleosides.

E. De Clercq, J. Balzarini, R. Snoeck, 1999, Journal of medicinal chemistry.

Drug targets in cytomegalovirus infection.

E. De Clercq, R. Snoeck, G. Andrei, 2009, Infectious disorders drug targets.

Polyanion inhibitors of human immunodeficiency virus and other viruses. Part 2. Polymerized anionic surfactants derived from amino acids and dipeptides.

E. De Clercq, S. Ikeda, J. Neyts, 1996, Journal of medicinal chemistry.

Polyanion inhibitors of HIV and other viruses. 7. Polyanionic compounds and polyzwitterionic compounds derived from cyclodextrins as inhibitors of HIV transmission.

E. De Clercq, C. Pannecouque, J. Neyts, 1998, Journal of medicinal chemistry.

Polyanion inhibitors of human immunodeficiency virus and other viruses. 6. Micelle-like anti-HIV polyanionic compounds based on a carbohydrate core.

E. De Clercq, M. Witvrouw, J. Esté, 1997, Journal of medicinal chemistry.

Polyanion inhibitors of human immunodeficiency virus and other viruses. 5. Telomerized anionic surfactants derived from amino acids.

E. De Clercq, J. Montero, M. Witvrouw, 1997, Journal of medicinal chemistry.

Polyanion inhibitors of human immunodeficiency virus and other viruses. 1. Polymerized anionic surfactants.

P. Barthélémy, A. Bousseau, J. Roque, 1995, Journal of medicinal chemistry.

Cidofovir in the treatment of HPV-associated lesions.

E. De Clercq, G. Andrei, R. Snoeck, 2001, Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie.

Ovine Skin Organotypic Cultures Applied to the Ex vivo Study of Orf Virus Infection

E. Clercq, A. Guercio, R. Snoeck, 2005, Veterinary Research Communications.

Differential Susceptibility of Several Drug-Resistant Strains of Herpes Simplex Virus Type 2 to Various Antiviral Compounds

E. De Clercq, R. Snoeck, G. Andrei, 1997 .

Synthesis and antiviral activity of three pyrazole analogues of distamycin A.

E. De Clercq, U. Ragnarsson, J. Balzarini, 1994, Acta chemica Scandinavica.

Synthesis and antiviral activity of 5'-deoxypyrazofurin.

E. De Clercq, S. Ikeda, J. Balzarini, 1993, Journal of medicinal chemistry.

Synthesis of 1-[ω-(Bromophenoxy)alkyl]-3-naphthalenylmethyl Derivatives of Uracil and Their Analogues As Probable Inhibitors of Human Cytomegalovirus Replication

S. Kochetkov, R. Snoeck, G. Andrei, 2023, Doklady Biochemistry and Biophysics.

Synthesis of 1-[ω-(Bromophenoxy)alkyl]-3-Naphthalenylmethyl Uracil Derivatives and Their Analogues as Probable Inhibitors of Human Cytomegalovirus Replication

S. Kochetkov, R. Snoeck, G. Andrei, 2022, Doklady Biochemistry and Biophysics.